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- 저자 : Manna Zhang (검색결과 3 건)
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Propagation Dynamics of a Finite-energy Airy Beam with Sinusoidal Phase in Optical Lattice
Xiaoyuan Huang,Manna Chen,Geng Zhang,Ye Liu,Hongcheng Wang 한국광학회 2020 Current Optics and Photonics Vol.4 No.4
The propagation of a truncated Airy beam with spatial phase modulation (SPM) is investigated in Kerr nonlinearity with an optical lattice. Before the truncated Airy beam enters the optical lattice, a sinusoidal phase is introduced on the wave-front of the beam. The effect of the spatial phase modulation and optical lattice on propagation behavior is analyzed by direct numerical simulation. It is found that the propagation direction of a truncated Airy beam can be effectively controlled by adjusting the values of phase shift. The effects of optical amplitude, truncation factor, spatial modulation frequency, lattice period and lattice depth on the propagation are discussed in detail. By choosing a high modulation depth, the finite-energy Airy beam can be deflected with a large deflection angle in an optical lattice.
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Nayak, Uma,Kanungo, Suman,Zhang, Dadong,Ross Colgate, E.,Carmolli, Marya P.,Dey, Ayan,Alam, Masud,Manna, Byomkesh,Nandy, Ranjan Kumar,Kim, Deok Ryun,Paul, Dilip Kumar,Choudhury, Saugato,Sahoo, Sushama John Wiley and Sons Inc. 2017 Maternal & child nutrition Vol.13 No.4
<P><B>Abstract</B></P><P>The lipid composition of breast milk may have a significant impact on early infant growth and cognitive development. Comprehensive breast milk data is lacking from low‐income populations in the Indian subcontinent impeding assessment of deficiencies and limiting development of maternal nutritional interventions. A single breast milk specimen was collected within 6 weeks postpartum from two low‐income maternal cohorts of exclusively breastfed infants, from Dhaka, Bangladesh (<I>n</I> = 683) and Kolkata, India (<I>n</I> = 372) and assayed for percentage composition of 26 fatty acids. Mature milk (>15 days) in Dhaka (<I>n</I> = 99) compared to Kolkata (<I>n</I> = 372) was higher in total saturated fatty acid (SFA; mean 48% vs. 44%) and disproportionately lower in ω3‐polyunsaturated fatty acid (PUFA), hence the ω6‐ and ω3‐PUFA ratio in Dhaka were almost double the value in Kolkata. In both sites, after adjusting for days of lactation, increased maternal education was associated with decreased SFA and PUFA, and increasing birth order or total pregnancies was associated with decreasing ω6‐PUFA or ω3‐PUFA by a factor of 0.95 for each birth and pregnancy. In Dhaka, household prosperity was associated with decreased SFA and PUFA and increased ω6‐ and ω3‐PUFA. Maternal height was associated with increased SFA and PUFA in Kolkata (1% increase per 1 cm), but body mass index showed no independent association with either ratio in either cohort. In summary, the socioeconomic factors of maternal education and household prosperity were associated with breast milk composition, although prosperity may only be important in higher cost of living communities. Associated maternal biological factors were height and infant birth order, but not adiposity. Further study is needed to elucidate the underlying mechanisms of these effects.</P>
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IL28B Is Associated with Outcomes of Chronic HBV Infection
Xiaodong Shi,Junqi Niu,Xiumei Chi,Yu Pan,Yanhang Gao,Wanyu Li,Chen Yang,Jin Zhong,Damo Xu,Manna Zhang,Gerald Minuk,Jing Jiang 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.3
Purpose: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes. Materialsand Methods: IL28B genetic variations (rs12979860) were genotyped by pyrosequencingof DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34 chronic hepatitis B (CHB), 27 cirrhosis, 26 hepatocellular carcinoma (HCC)], and 19 healthy controls. IL28A/B mRNA expression in peripheralblood mononuclear cells was determined by qRT-PCR, and serum IL28B proteinwas measured by ELISA. Results: Patients with IL28B C/C genotype had greater IL28A/B mRNA expression and higher IL28B protein levels than C/T patients. Within the various disease stages, compared to IC and healthy controls, IL28B expression was reduced in the CHB, cirrhosis, and HCC cohorts (CHB vs. IC, p=0.02; cirrhosis vs. IC, p=0.01; HCC vs. IC, p=0.001; CHB vs. controls, p<0.01; cirrhosis vs. controls, p<0.01; HCC vs. controls, p<0.01). When stratified with respect to serum HBV markers in the IC and CHB cohorts, IL28B mRNA and protein levels were higher in HBeAg-positive than negative individuals (p=0.01). Logistic regression analysis revealed that factors associated with high IL28B proteinlevels were C/C versus C/T genotype [p=0.016, odds ratio (OR)=0.25, 95% confidence interval (CI)=0.08‒0.78], high alanine aminotransferase values (p<0.001, OR=8.02, 95% CI=2.64‒24.4), and the IC stage of HBV infection (p<0.001). Conclusion: Our data suggest that IL28B genetic variations may play an important role in long-term development of disease in chronic HBV infections.
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