Mediterranean Diet and Overactive Bladder

Yunus Erol Bozkurt,Gökhan Temeltaş,Talha Müezzinoğlu,Oktay Üçer 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.2

Purpose: The relationship between nutrition and overactive bladder (OAB) has yet to be elucidated. Therefore, this study investigated the relationship between the Mediterranean diet and OAB. Methods: The 14-item Mediterranean Diet Adherence Screener (MeDAS) and Overactive Bladder-Validated 8-question Screener (OAB-V8), validated in Turkish, were administered to 500 patients over the age of 18 who presented to outpatient clinics other than urology outpatient clinics. Of those patients, 174 with chronic diseases and urinary tract infections (based on urinalysis and a detailed medical history) were excluded. Therefore, 326 patients’ data were analyzed. Results: There was a negative correlation between the MeDAS and OAB-V8 scores. High OAB-V8 scores were associated with obesity (body mass index ≥30 kg/m2 ), being single, and a low education level. Conclusions: Dietary patterns represent a broader perspective on food and nutrient consumption and may therefore be more predictive of disease risk. The Mediterranean type should be recommended in the first-line treatment of patients with OAB symptoms. It is easily possible to determine the compliance of patients with this diet by using the 14-item MeDAS.

Concurrent Assay for Four Bacterial Species Including Alloiococcus Otitidis in Middle Ear, Nasopharynx and Tonsils of Children with Otitis Media with Effusion: A Preliminary Report

Emine Aydın,Eren Taştan,,Filiz Aydoğan,,Esra Karakoç,Yunus Kantekin,Münir Demirci,Mihriban Yücel,Necmi Arslan 대한이비인후과학회 2012 Clinical and Experimental Otorhinolaryngology Vol.5 No.2

Objectives. To detect the prevalences of Alloiococcus otitidis, as well as Haemophilus influenzae, Streptococcus pneumoniae,and Moraxella catarrhalis in children with chronic otitis media with effusion (OME) and to simultaneously investigate the colonization of these bacteria in the nasopharynx and palatine tonsils of these patients. Methods. The study included 34 pediatric patients with OME, and 15 controls without OME. In the study group, A. otitidis,H. influenzae, S. pneumoniae, and M. catarrhalis were investigated in the samples obtained from middle ear effusions (MEE), nasopharyngeal swabs (NPS) and tonsillar swabs (TS), using multiplex polymerase chain reaction (PCR) and conventional culture methods. Only the samples obtained from NPS and TS were studied with the same techniques in the control group. Results. A. otitidis was isolated only in MEE and only with multiplex PCR method. A. otitidis, S. pneumoniae, M. catarrhalis,H. influenzae were identified in 35%, 8.8%, 8.8%, and 2.9%, respectively, in 34 MEE. A. otitidis was not isolated in NPS or TS of the study and the control groups. Conclusion. The prevalence of A.otitidis is high in children with OME and A.otitidis doesn’t colonize in the nasopharynx or tonsil. Objectives. To detect the prevalences of Alloiococcus otitidis, as well as Haemophilus influenzae, Streptococcus pneumoniae,and Moraxella catarrhalis in children with chronic otitis media with effusion (OME) and to simultaneously investigate the colonization of these bacteria in the nasopharynx and palatine tonsils of these patients. Methods. The study included 34 pediatric patients with OME, and 15 controls without OME. In the study group, A. otitidis,H. influenzae, S. pneumoniae, and M. catarrhalis were investigated in the samples obtained from middle ear effusions (MEE), nasopharyngeal swabs (NPS) and tonsillar swabs (TS), using multiplex polymerase chain reaction (PCR) and conventional culture methods. Only the samples obtained from NPS and TS were studied with the same techniques in the control group. Results. A. otitidis was isolated only in MEE and only with multiplex PCR method. A. otitidis, S. pneumoniae, M. catarrhalis,H. influenzae were identified in 35%, 8.8%, 8.8%, and 2.9%, respectively, in 34 MEE. A. otitidis was not isolated in NPS or TS of the study and the control groups. Conclusion. The prevalence of A.otitidis is high in children with OME and A.otitidis doesn’t colonize in the nasopharynx or tonsil.

Effect of Glucose and Formic Acid on the Quality of Napiergrass Silage After Treatment With Urea

Yunus, M.,Ohba, N.,Tobisa, M.,Shimojo, M.,Masuda, Y. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.2

Urea as a silage additive increases crude protein but reduces fermentation quality of silage by increasing pH and enhancing clostridial bacteria growth, especially in low sugar forages. Glucose and formic acid might be expected to compensate these defects caused by urea addition to grass silage. Thus, in this experiment urea formic acid or urea with glucose was applied to improve N content and the quality of napiergrass (Pennisetum purpureum Schumach.) silage. The first growth of napiergrass was harvested at 85 days of age and about 700 g of the grass was ensiled in laboratory silos (1.0 liter polyethylene containers) for 2, 7, 14, and 30 days at room temperature ($28^{\circ}C$). The treatments were no additives (control), urea, urea+glucose or urea+formic acid. Urea was added before ensiling at 0.5% of fresh weight of napiergrass and glucose and formic acid were added at 1% of fresh weight, respectively. After opening the silo, pH, dry matter content (DM), contents on DM basis of total N (TN), volatile basic nitrogen (VBN), lactic acid (LA), acetic acid (AA) and butyric acid (BA) were determined. The control at 30 days of fermentation showed 5.89 for pH with 13.8% for VBN/TN and 1.51% for AA. The addition of urea increased TN by about 1.5% units but decreased the fermentation quality by increasing pH from 5.89 to 6.86, increasing VBN/TN from 13.8% to 24.63%, increasing BA from 0.02% to 0.56%, and decreasing LA from 1.03% to 0.02%. Glucose addition with urea significantly decreased VBN/TN from 13.8% to 4.44% by reducing pH from 6.86 to 4.83 because of higher production of LA (2.62%). Adding urea and formic acid resulted in a more pronounced depression of VBN/TN and fermentation than the addition of urea and glucose. This study suggested that the combination of 1% glucose or 1% formic acid with 0.5% urea will improve nutritive value and fermentation quality of napiergrass silage.

Sensitivity of stabilized a-Se based X-ray photoconductors

M. Zahangir Kabir,M. Yunus,S.O. Kasap,O. Tousignant,H. Mani,P. Gauthier 한국물리학회 2006 Current Applied Physics Vol.6 No.3

A model explaining the ghosting mechanisms in amorphous selenium based X-ray image detectors is described by considering deeptrapping of charge carriers, trapped charges arising from previous exposures, trap lling eects, recombination between drifting andtrapped carriers, generation of X-ray induced new deep trap centers, space charge eects, carrier detrapping, and electric eld dependenttions, and the Poisson’s equation across the photoconductor for a pulse X-ray exposure by the nite dierence method. The numericalresults are compared with Monte Carlo simulations. The relative sensitivity decreases with increasing accumulative X-ray exposure anddecreasing applied electric eld. The sensitivity reduction at negative bias is greater than at positive bias. The theoretical model is tted toexperimental data. The comparison of the model with the experimental data reveals that the recombination between trapped and theoppositely charged drifting carriers, electric eld dependent charge carrier generation and X-ray induced new deep trap centers are mainly responsible for the sensitivity reduction in biased amorphous selenium based X-ray detectors.

Improving Fermentation and Nutritive Quality of Napiergrass Silage by Mixing with Phasey Bean

Yunus, M.,Ohba, N.,Tobisa, M.,Nakano, Y.,Shimojo, M.,Furuse, M.,Masuda, Y. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.7

To improve the low content of crude protein and low quality fermentation of napiergrass silage, ensiling with phasey bean was examined. Napiergrasses, (Pennisetum purpureum cv. Merkeron), hybrid napiergrass (Pennisetum purpureum${\times}$ Pennisetum typhoides) and phasey bean (Macroptilium lathyroides cv. Murray) were cultivated in Fukuoka, Japan. The first growth of napiergrasses and phasey bean were harvested at 90 days of age and chopped into about 1 cm lengths. The mixing levels of phasey bean with napiergrasses were 0, 25, 50 and 75; 700 g of plant materials were ensiled into a laboratory silo (1.0 litre. polyethylene container) and incubated for 30 days. After opening silos, pH, total nitrogen (TN), volatile basic nitrogen (VBN) and organic acids (lactic acid: LA, acetic acid: AA, butyric acid: BA) were determined. The experiment was a factorial design of $2{\times}4$ with 3 replicates. The data were analyzed statistically by two-way analysis of variance. Without inclusion of phasey bean, lower quality was observed for hybrid silage than for Merkeron silage. The inclusion of phasey bean at the rate of 25% increased DM and TN, and decreased pH value, VBN/TN, AA and BA in both Merkeron and hybrid napiergrass silages. The value of pH, TN, VBN/TN, AA and BA were not significantly different among 25, 50 and 75% mixing levels of phasey bean. LA production increased significantly with the increase in phasey bean mixing level in both hybrid and Merkeron silages. At all mixing levels of phasey bean, LA production did not show significant differences between Merkeron and hybrid silages.

Effects of Adding Urea and Molasses on Napiergrass Silage Quality

Yunus, M.,Ohba, N.,Shimojo, M.,Furuse, M.,Masuda, Y. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.11

To standardize proper formulation of urea and molasses, the former to increase crude protein content of tropical grass and the latter for improving its silage quality, we examined the fermentation quality of silage of fresh and wilted napiergrass (Pennisetum purpureum Schumach) with different levels of urea and molasses with or without lactic acid bacteria (LAB). Silage was made of napiergrass with conditions of fresh young (Exp. 1),young wilted for half day (Exp. 2) and fresh mature (Exp. 3). Chopped plant materials of about 1cm length were ensiled into a laboratory silo and incubated for one month at $25^{\circ}C$. The treatments were the combination of 0, 0.2 and 0.6% of urea and 0, 2 and 5% of molasses (fresh material basis) with or without LAB inoculation. After opening the silo, pH, organic acids, volatile basic nitrogen (VBN) and total nitrogen (TN) were determined. Addition of molasses significantly (p<0.01) lowered pH values in three experiments. Though molasses addition increased lactic acid production even at a higher level of urea, pH values at 0 and 2% molasses were significantly increased by urea in fresh and wilted young silages, but in fresh mature silage it occurred only when molasses was not added. VBN/TN at 0.6% urea were decreased significantly by the highest molasses in three experiments. Significant increases in TN by the increasing of urea addition were observed at all levels of molasses in wilted young and fresh mature silages. In conclusion, a combination of 5% molasses and 0.6% urea could improve the nutritive and fermentation qualities of napiergrass silage under young, wilting and mature conditions.

Effects of Preheated Additives on the Fermentation Quality of Napiergrass Silage

Yunus, M.,Ohba, N.,Tobisa, M.,Shimojo, M.,Masuda, Y. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.11

Hydrolysis of plant protein to non-protein nitrogen (N) or ammonia can reduce quality of silage crops. Heating or non-enzymatic browning is a treatment to inhibit this hydrolysis. This experiment was conducted to examine the effects of pre-heated soybean meal and molasses on the fermentation quality of napiergrass silage. The initial growth of napiergrass was harvested at 85 days of age and immediately chopped into about 1 cm length. About 700 g of the grass was ensiled into a laboratory silo (1.0 liter polyethylene container) and incubated for 30 days at room temperature ($28^{\circ}C$). No additives (control), molasses, soybean meal and molasses + soybean meal treatments were prepared. All additives were non-heated or heated in an oven at $150^{\circ}C$ for 30 minutes before ensiling. Molasses was added at 3% on the fresh weight basis and soybean meal was added at 0.5% N, respectively. After opening the silo, pH, total nitrogen (TN), volatile basic nitrogen (VBN), lactic acid (LA), acetic acid (AA), butyric acid (BA) and dry matter (DM) contents were determined. The data were analyzed statistically by analysis of variance. Compared with control, molasses addition significantly decreased pH value, VBN/TN, AA and BA and increased LA production. Soybean meal addition significantly increased TN and VBN/TN of silage. Both molasses and soybean meal addition significantly reduced pH value, AA, and BA and increased DM and LA contents of silage. The heating of additives was only effective to reduce VBN/TN production compared with non-heated additives in soybean meal and soybean meal with molasses addition.

CORRELATION BETWEEN TESTICLE MEASUREMENTS AND LIBIDO AND SEMEN QUALITY IN RAMS

Wahid, S.A.,Yunus, J.M. Asian Australasian Association of Animal Productio 1994 Animal Bioscience Vol.7 No.2

A study was conducted at Ijok, Malaysia, to determine the relationship of testicular measurements with libido and semen quality in tropical and imported temperate breeds of sheep. Ten rams each of Malin (M), Siamese Longtail (L), Cross of Merino with Border Leicester (C), Dorset (D) and Suffolk (S) were used for the study. Libido, semen volume and semen quality were recorded monthly for a year together with testicular length, width and circumference. The results showed that there were breed differences in volume and quality of semen where the tropical breeds had better semen compared to the temperate breeds. There was positive and significant correlation between testicle length and semen volume in all the breeds. Testicular length was found to be positively and significantly correlated with motility and sperm concentration in the tropical breeds (L and M). The relationship between libido and testicle measurements in the tropical breeds was not significant (p<0.05). There was variable relationship between the testicular measurements and libido in the temperate breeds where the relationship was significant and negative in breeds C and D and highly significant and positive in S. It was evident that the long testicles influenced the quality of the semen whereas testicles with greater circumference influenced the libido of the rams.

Effects of Substituting Cottonseed Meal with Sunflower Meal in Rations for Growing Buffalo Calves

Yunus, A.W.,Khan, A.G.,Alam, Z.,Sultan, J.I.,Riaz, M. Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.5

A growth trial of 60 days with 16 male buffalo calves (10 to 11 months age; 100${\pm}$7 kg live weight mean) was conducted to investigate comparative efficacy of cottonseed meal (CSM) and sunflower meal (SFM). Cottonseed meal was substituted isonitrogenously with SFM at 0, 12, 24 and 36% levels in four rations viz. A, B, C and D. Daily feed consumption was 5.07, 4.30, 4.17 and 3.20 kg, while daily weight gain was recorded to be 0.98, 0.74, 0.57 and 0.33 kg under rations A, B, C and D, respectively. In the digestibility and nitrogen balance trial using eight calves, digestibility of organic matter was 63.2, 62.9, 62.1 and 61.7, respectively. Nitrogen retained as percent of intake did not differ significantly. Sunflower meal was purchased at half the price of CSM but economics of weight gain did not favor SFM inclusion in rations. Results suggested that SFM should not be fed to buffalo calves gaining more than 0.7 kg/day.

DrugeDNA interaction: A theoretical study on the binding of thionine with DNAs of varying base composition

G. Yunus,S. Srivastava,M. Kuddus,V.D. Gupta 한국물리학회 2013 Current Applied Physics Vol.13 No.2

The recent studies carried out on the binding of small molecule to deoxyribonucleic acids suggested that the intercalation of a tricyclic heteroaromatic molecule, thionine, with natural DNAs provided thermal stabilization to the DNA complex. In the present study, we reported theoretical analysis of thionine binding with natural DNAs of varying base composition by using an amended Zimm and Bragg theory, to explain the melting behaviour and heat capacity of DNAs with and without thionine binding. We used experimental models of Paul et al. for implementing this study (Paul et al., 2010). The sharpness of transition has been examined in terms of half width and sensitivity parameter (DH/s). The results of theoretical analysis concluded that the various parameters such as heat capacity curve, transition profile, half widths and sharpness of the transition are in good agreement with the experimental measurements for binding of thionine determined through DSC. The theoretical analysis proposed in this study, therefore, may be useful to understand interaction of small molecules with deoxyribonucleic acids. This approach may also be applied to design DNA binding therapeutic molecules and in the process of drug formulation and development.