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      • KCI등재

        Tailoring physical and chemical microenvironments by polyether-amine in blended membranes for efficient CO2 separation

        Xia Lv,Xueqin Li,Lu Huang,Siyuan Ding,Yin Lv,Jinli Zhang 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.3

        Pebax® MH 1657 (Pebax)-based blend membranes with different polyether-amine (PEA) loadings were designed and fabricated for efficient CO2 separation. The CO2 separation performance of Pebax/PEA blend membranes was greatly improved in comparison with that of pure membranes. This was mainly because the introduced PEA tailored the physical and chemical microenvironments in blend membranes. Specifically, PEA was a liquid-like additive, which was beneficial to reduce the mass transfer resistance of gases and increase CO2 permeability. Meanwhile, PEA contained amino groups that acted as mobile carriers to tailor the chemical microenvironment in blend membranes. The mobile carriers preferentially reacted reversibly with CO2 molecules, facilitating CO2 transport in membranes. Compared with CO2/CH4 separation performance of pure Pebax membrane, CO2 permeability and CO2/CH4 separation factor of Pebax/PEA-3 increased by 144.8% and 29.4%, respectively. This study suggests that PEA is a promising membrane material for tailoring the physical and chemical microenvironments in blend membranes for efficient CO2 separation.

      • KCI등재

        Expression, Purification, and Characterization of a Recombined Fibrinolytic Enzyme from Endophytic Paenibacillus polymyxa EJS-3 in Escherichia coli

        Fengxia Lv,Chong Zhang,Fangfang Guo,Yingjian Lu,Xiaomei Bie,Hui Qian,Zhaoxin Lu 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.1

        The gene encoding the fibrinolytic enzyme (PPFE-I) from Paenibacillus polymyxa EJS-3 was cloned and sequenced (Genbank No. KC176802). The 1773 bp gene encoded 590 amino acids and had low homology with other known fibrinolytic enzymes. PPFE-I was soluble and expressed in E. coli BL21 to enhance the activity. The recombinant enzyme (rPPFE-I) was purified to homogeneity, and enzymatic properties were characterized. The optimal temperature and pH for rPPFE-I were 37℃ and 7.5, respectively. Observed activities of rPPFE-I were highest in the presence of Zn2+, Mg2+, and Fe2+ and the lowest in the presence of Ca2+ and Cu2+. The rPPFE-I activity was strongly inhibited by PMSF. The α-chain was affected by the rPPFE-I cleavage speed of fibrinogen, followed by the b and γ chains. The inhibitory effects of rPPFE-I against ADP-induced human platelet aggregation were dosedependent with an IC50 value of 1.54 μM.

      • SCIESCOPUSKCI등재

        Frequency-Code Domain Contention in Multi-antenna Multicarrier Wireless Networks

        Lv, Shaohe,Zhang, Yiwei,Li, Wen,Lu, Yong,Dong, Xuan,Wang, Xiaodong,Zhou, Xingming The Korea Institute of Information and Commucation 2016 Journal of communications and networks Vol.18 No.2

        Coordination among users is an inevitable but time-consuming operation in wireless networks. It severely limit the system performance when the data rate is high. We present FC-MAC, a novel MAC protocol that can complete a contention within one contention slot over a joint frequency-code domain. When a node takes part in the contention, it generates randomly a contention vector (CV), which is a binary sequence of length equal to the number of available orthogonal frequency division multiplexing (OFDM) subcarriers. In FC-MAC, different user is assigned with a distinct signature (i.e., PN sequence). A node sends the signature at specific subcarriers and uses the sequence of the ON/OFF states of all subcarriers to indicate the chosen CV. Meanwhile, every node uses the redundant antennas to detect the CVs of other nodes. The node with the minimum CV becomes the winner. The experimental results show that, the collision probability of FC-MAC is as low as 0.05% when the network has 100 nodes. In comparison with IEEE 802.11, contention time is reduced by 50-80% and the throughput gain is up to 200%.

      • KCI등재

        Identification and characterization of presence/absence variation in maize genotype Mo17

        Lu Jiang,Yuanda Lv,Tan Li,Han Zhao,Tifu Zhang 한국유전학회 2015 Genes & Genomics Vol.37 No.6

        Presence/absence variation (PAV), a major class of genome structure variation, is pervasive in the maize genome. PAVs present in the B73 but absent from the Mo17 genome have been reported in previous studies. Here, the next-generation sequencing was used to identify the PAVs present in Mo17 but absent from B73. A total of 119 PAVs were identified, of which 57 were validated by PCR. Using the intermated B73 9 Mo17 segregating population, 57 validated PAVs were mapped into the genetic map. These PAVs were dispersed on the ten chromosomes. Also, several large genetic regions of PAVs were identified. This suggested the possibility that large genetic fragments in Mo17 were absent from the B73 genome. Several PAVs were also found to be related to disease resistance suggesting that presence/absence variations in the genome may play a role in disease resistances in maize. In addition, the majority of the genes within PAV were transcriptionally silenced or expressed at low levels in some tissues, especially for PAVs related to disease resistance. The results of this study not only provided the identities of additional PAVs in maize but also helped understand the functional role of PAVs in this agriculturally important crop.

      • KCI등재

        Pattern Recognition of Partial Discharge in Power Transformer Based on InfoGAN and CNN

        Lv Fangcheng,Liu Guilin,Wang Qiang,Lu Xiuquan,Lei Shengfeng,Wang Shenghui,Ma Kang 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.2

        As an important equipment in the power system, it has a significant meaning in scientifically diagnosing the insulation state of oil-immersed power transformers. At present, the pattern recognition of partial discharge (PD) in a transformer has the problem of the insufficient generalization ability of the classifier due to scarcity and imbalance of samples, resulting in low recognition accuracy. To solve this problem, this paper proposes a pattern recognition of the PD method based on information maximizing generative adversarial nets (InfoGAN) and convolutional neural networks. In this method, phase-resolved partial discharge (PRPD) maps, constructed from pulse current waveforms, are chosen as the training samples. First, the InfoGAN is trained to generate new samples which expanded the original sample database, then various classifiers are trained by using the expanded sample database to realize the pattern recognition. Results of the test show that the proposed method can generate new highly similar samples more stable than other data enhancement methods, and effectively enrich the data diversity. In addition, the classifier trained by the expanded sample database has better generalization ability and is applicable to different classifiers, while residual network 18 has the highest recognition rate of 99.0%. This method can effectively balance and expand PRPD samples, and improve the recognition accuracy of the classifier to a certain extent. It has a good application prospect in PD diagnosis engineering.

      • Efficacy and Safety of Endostar<sup>®</sup> Combined with Chemotherapy in Patients with Advanced Soft Tissue Sarcomas

        Zhang, Lu-Ping,Liao, Xing-Yun,Xu, Yan-Mei,Yan, Lv-Jun,Yan, Gui-Fang,Wang, Xin-Xin,Duan, Yu-Zhong,Sun, Jian-Guo Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

        Background: Soft tissue sarcomas (STS) are a heterogeneous group of tumors, and approximately 40-50% of patients with STS develop metastatic disease. The median overall survival of those patients was 12 months and their 5-year survival rate was 8%. Therefore, study on more effective treatment, especially the targeting therapies, is urgently needed. Objective: To evaluate the efficacy and safety of Endostar$^{(R)}$ combined with chemotherapy in patients with advanced STS. Methods: A retrospective case-series study was conducted in Cancer Institute of PLA, Xinqiao Hospital. A total of 71 patients suffering from advanced STS (IIB - IV) were included, of whom 49 cases treated with chemotherapy alone were defined as the control group and the rest 22 cases treated with the traditional chemotherapy combined with Endostar$^{(R)}$ were defined as the test group. The short-term therapeutic effects including objective response rate (ORR), disease control rate (DCR) and safety were evaluated in the two groups. In the follow-up, progression-free survival (PFS) and overall survival (OS) were also observed. Results: In the test and control groups, the ORR was 18.2% and 12.2%, respectively (P=0.767), and the DCR was 86.4% and 61.2%, respectively (P=0.034). The median time to progression in the test and control groups was 120 days and 70 days with significant difference (P = 0.017), while the median overall survival was 452 days and 286 days without significant difference (P=0.503). The one-year survival rate in the test group and control group was 56.2% and 35.4%, respectively, while the two-year survival rate was 30.2% and 26.5%, respectively. No significant difference in the side effects was found between the two groups. Conclusions: Endostar$^{(R)}$ combined with chemotherapy resulted in a higher DCR and longer PFS in the patients with advanced STS, and the toxicity was tolerable.

      • KCI등재

        Operation start time and long-term outcome of hepatocellular carcinoma after curative hepatic resection

        Qiang Lu,Qing-Shan Li,Wei Zhang,Kang Liu,Tao Li,Jia-Wei Yu,Yi Lv,Xu-Feng Zhang 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.99 No.1

        Purpose: The objective of the current study was to examine the potential effects of surgery start times (morning vs. afternoon) on the long-term prognosis of patients after hepatic resection (HR) for hepatocellular carcinoma (HCC). Methods: All eligible patients were divided into 2 groups according to the start time of surgery: group M (morning surgery, 8 AM–1 PM) and group A (afternoon surgery, 1 PM–6 PM). Clinicopathologic and surgical parameters, as well as oncologic outcomes were compared between the 2 groups. Results: In total, 231 patients were included in the study. There was no difference in age, body mass index, comorbidities, tumor size, tumor location, tumor stages, surgical procedures, or surgical margin between morning and afternoon surgery (all P > 0.05). In contrast, patients in group M experienced longer operation duration than those in group A (median, 240 minutes vs. 195 minutes, P = 0.004). However, no differences of overall survival were observed between morning and afternoon surgery groups in the whole cohort or stratified by surgical margin (all P > 0.05). Conclusion: Surgery start times during the work day have no measurable influence on patient outcome following curative HR for HCC, indicating good self-regulation and professional judgment of surgeons for progressive fatigue during surgery

      • KCI등재

        The strength analysis and probabilistic design of a bogie frame with incomplete probabilistic information

        Hao Lu,Changyi Wang,Haibao Guo,Hao Lv,Yimin Zhang 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.3

        A bogie frame is a key component of high-speed rail; higher requirements of the safety and stability of the bogie frame are put forward with the continuous improvement of the train speed. In this study, we first performed a strength analysis of a bogie frame according to the JIS E 4207 standard by using finite element method. Then, we did a reliability analysis of the bogie frame. The reliability problems are defined as strength reliability and resonant frequency reliability, which indicate the structural safety and stability of the bogie frame. The reliability estimation is realized by experimental design, artificial neural network and stochastic perturbation theory. Additionally, reliability-based sensitivity indices were derived to measure the parameter importance of random input variables. An illustrative example of the bogie frame with incomplete probabilistic information was used to demonstrate the applications of the proposed method for reliability and reliability-based sensitivity estimation in terms of strength and resonant frequency reliability. The results indicate that vertical loads and the material density have more of an impact on reliability than other variables of the bogie frame.

      • KCI등재

        DMRUT-MCDS: Discovery Relationships in the Cyber-Physical Integrated Network

        Hongliang Lu,지아농챠오,Weiping Zhu,Xianlong Jiao,Shaohe Lv,Xiaodong Wang 한국통신학회 2015 Journal of communications and networks Vol.17 No.6

        In recent years, we have seen a proliferation of mobilenetwork- enabled smart objects, such as smart-phones and smartwatches, that form a cyber-physical integrated network to connect the cyber and physical worlds through the capabilities of sensing, communicating, and computing. Discovery of the relationship between smart objects is a critical and nontrivial task in cyber-physical integrated network applications. Aiming to find the most stable relationship in the heterogeneous and dynamic cyber-physical network, we propose a distributed and efficient relationship-discovery algorithm, called dynamically maximizing remaining unchanged time with minimum connected dominant set (DMRUT-MCDS) for constructing a backbone with the smallest scale infrastructure. In our proposed algorithm, the impact of the duration of the relationship is considered in order to balance the size and sustain time of the infrastructure. The performance of our algorithm is studied through extensive simulations and the results show that DMRUT-MCDS performs well in different distribution networks.

      • KCI등재

        Frequency-Code Domain Contention in Multi-antenna Multicarrier Wireless Networks

        Shaohe Lv,Yiwei Zhang,Wen Li,Yong Lu,Xuan Dong,Xiaodong Wang,Xingming Zhou 한국통신학회 2016 Journal of communications and networks Vol.18 No.2

        Coordination among users is an inevitable but timeconsumingoperation in wireless networks. It severely limit thesystem performance when the data rate is high. We present FCMAC,a novel MAC protocol that can complete a contention withinone contention slot over a joint frequency-code domain. When anode takes part in the contention, it generates randomly a contentionvector (CV), which is a binary sequence of length equalto the number of available orthogonal frequency division multiplexing(OFDM) subcarriers. In FC-MAC, different user is assignedwith a distinct signature (i.e., PN sequence). A node sendsthe signature at specific subcarriers and uses the sequence of theON/OFF states of all subcarriers to indicate the chosen CV. Meanwhile,every node uses the redundant antennas to detect the CVsof other nodes. The node with the minimum CV becomes the winner. The experimental results show that, the collision probabilityof FC-MAC is as low as 0.05% when the network has 100 nodes. In comparison with IEEE 802.11, contention time is reduced by50–80% and the throughput gain is up to 200%.

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