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      • COMMON STATIONARY POINTS OF MULTI-VALUED F-CONTRACTIONS WITH δ-DISTANCE

        Liu1 Zeqing,Liu Ying,Kang Shin Min 경남대학교 기초과학연구소 2019 Nonlinear Functional Analysis and Applications Vol.24 No.1

        Three common stationary point theorems for some multi-valued F-contractions with δ-distance in bounded complete metric spaces are proved. The results obtained in this paper are extended or are different from several results in the literature. Three nontrivial examples are given.

      • KCI등재

        한ㆍ중 고사성어 대조 연구

        LIU YING 국제한국언어문화학회 2014 한국언어문화학 Vol.11 No.2

        한국과 중국의 역사를 살펴보면 한국과 중국은 지리상으로 인접해있어 수천 년 전부터 교류를 시작한 사실을 알 수 있다. 양국의 크고 작은 교류를 통해 중국의 한자어가 한국으로 전파되었다. 고사를표현하는 형식이 간 결하고 독특한 언어형식인 고사성어(故事成語)도한자어의 일부분으로서 한국으로 전파되어 수천 년의 세월 동안 한국의 정치, 경제, 사회, 문화의 영향을 받으면서 발전해왔다. 마찬가지로 중국에서도 고사성어는 중국 의 정치, 경제, 사회, 문화에 영향을 받으면서 발전해 온 결과로 한국과 중국의 일부 고사성어는 개념과 형식, 그리고 용법이 서로 상이하게 변하였다. 1992년 한 중양국이 수교하면서 중국인 한국어 학습자가 점차 증가하 였다. 한국사회생활에 많이 쓰이는 고사성어는 한국어 학습자에게도 중요한학습 내용이다. 뿐만 아니라 한국 어능력시험(TOPIK-Test of Proficiencyin Korean)에도 거의 매번 고사성어가 출제되고 있다. 중국인 한국어 학습자에게 한국의 고사성어는 중국어와 동일한 부분도많으나 유사하거나 상이한 부분도 있어 한국의 고사성 어 학습에 어려움이 있을 수 있다. 이 논문은 우선 한국에서 중요하게 사용되고 있는 고사성어를 선정하기 위해 TOPIK 문제집(7회부터 33회까지 ), 한국의 중학교 한문교과서 및 고등학교 한문교과서를 조사하여 여기에 나타난 고사성어를 연구대상으로 하 였다. 형식과 의미 두 가지 관점에서 한국의 고사성어와 중국어의 대응 형식을 대조하고, 한국의 고사성어와 중국의 고사성어 형식과 의미상의 차이와 그 차이가 나타난 원인을 분석하였다. 그리고 대조와 분석을 통해 중국인 한국어 학습자에게 한국 고사성어를 가르칠 때 유의해야 할 점을 제시하였다. (하얼빈사범대학교) Liu Ying. 2014. A Comparative Analysis of the story-basedidioms between Chinese and Korean. Journal of the InternationalNetwork for Korean Language and Culture 11-2, 53-78. The timewhen the Chinese characters began to be introduced to Koreacan be dated back to thousands of years ago, followed by theexport of idioms with their stories as an integrate part ofChinese characters. Since the establishment of diplomatic relationbetween the P.R.C and the R.O.K in 1992, South Korea hasreceived an increasing number of Chinese students who foundthemselves more and more frequently exposed to idioms andstories in their daily life in South Korea. Furthermore, theseidioms and their stories is a must in the S- TOPIK. Important asit is, the Chinese are prone to confuse the meaning of theseidioms with their versions in China. This thesis, focused on idioms and their stories selected from theS-TOPIK (the 7th–the 33rd) and Chinese literature textbooks ofjunior high and senior high. The differences of the idioms andtheir stories from the perspective of form and meaning areanalyzed in this paper, and it provides Chinese students withinstructions and guidelines to follow in learning Korean. (HarbinNormal University)

      • KCI등재

        朝鮮人視城中的乾隆皇帝 : 以《熱河日記》爲中心

        劉广銘,金英今 中韓人文科學硏究會 2008 한중인문학연구 Vol.24 No.-

        박지원 등이 창조한 건륭황제의 형상은 '객관화'됨으로써 동시대와 후세의 조선인들이 건륭황제를 묘사하는 데 있어서 원초적인 경험을 제공해주는 '기본 텍스트'로 작용하여 왔고 앞으로도 장기간에 걸쳐 건륭황제와 그 가족을 해석하는 기틀로 작용하게 될 것이다. 박지원이 묘사한 건륭황제는 조선조시기라는 역사적인 배경에서 이루어진 것인 동시에 박지원은 또한 조선조시기라는 역사적인 배경을 이루는 한 요소이기도 하다. 다시 말하면 사회집단의 상상력과 텍스트 사이의 관계는 전자가 후자를 제약하는 단선적인 영향관계가 아니라 양자가 서로 영향주는 관계, 일종의 교호적인 대화과정에 처해 있으며 부단한 대화과정에서 끊임없이 새로운 의의가 생성되고 새로운 형상이 탄생하게 되는 것이다. The objective image of Emperor Qianlong created by Pak Chi-Won is regarded as the pre-interpretation of the emperor. Such an image not only made the foundation for those Koreans in the same and following periods but also constrained the followers' interpretation of Qianlong and his family for a long time. Though the interpretation of Qianlong by Pak Chi-Won was constrained in the context of Li Dynasty, his interpretation also contributed to the creation of the context. It means the relation between virtual world of the community and text is not that the former one influences and constrains the later one but they interact with each other. They have an iterative dialogue relation. In such iterative dialogues new meanings and new images are continuously created.

      • Detection and Analysis of Residual Pesticides Based On Surface Raman Spectra of Spinach

        Liu Ying-Nan,Yi Shu-Juan 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.12

        This paper with spinach as the research object, to chlorpyrifos pesticide as detection object, using Raman spectroscopy technique surface pesticides in spinach residual detection method and rapid detection research. Starting from the detection method, study of the classic method and method for rapid detection of current situation of the development, Raman spectroscopy detection method as a means of detection, the selected object of study; master the Raman spectroscopy for rapid detection of the basic principles and originpro 9.0 software acquisition function using, lay the foundation for the subsequent detection of. After the actual test to determine Raman spectroscopy instrument laser wavelength to 473nm, acquisition time 2s spinach sample testing effect Best result. After no medicine Raman spectra to obtain the surface of spinach were denoising analysis results show that wavelet de noise method compared to the adjacent averaging, savitzky Golay method smoothing, median method effect better. On Spinach with different concentrations of chlorpyrifos Raman spectroscopy analysis that accorded with the residual linear relationship. The peak intensity method were selected to establish models were detected in spinach surface of pesticide chlorpyrifos. Raman spectroscopy detection method can of spinach surface of pesticide residues detection analysis. It solves the traditional measurement method for sample pretreatment is complex and long detection time, low efficiency of the measured defect

      • KCI등재

        Involvement of the Ca2+ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation

        Ying-Xiao Fu,Jian-Hong Gu,Yi Wang,Yan Yuan,Xue-Zhong Liu,Jian-Chun Bian,Zong-Ping Liu 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.2

        The purpose of this study was to determine whether the Ca2+ signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were incubated with macrophage colony-stimulating factor (M-CSF) + receptor activator of nuclear factor-κB ligand (RANKL) to stimulate osteoclastogenesis and then treated with different concentrations of OPG, an inhibitor of osteoclast differentiation. The intracellular Ca2+ concentration [Ca2+]i and phosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in the different treatment groups were measured by flow cytometry and Western blotting, respectively. The results confirmed that M-CSF + RANKL significantly increased [Ca2+]i and CaMKII phosphorylation in osteoclasts (p < 0.01), and that these effects were subsequently decreased by OPG treatment. Exposure to specific inhibitors of the Ca2+ signaling pathway revealed that these changes varied between the different OPG treatment groups. Findings from the present study indicated that the Ca2+ signaling pathway is involved in both the regulation of osteoclastogenesis as well as inhibition of osteoclast differentiation and activation by OPG.

      • ReaxFF Molecular Dynamics Simulations of Water Stability of Interpenetrated Metal–Organic Frameworks

        Liu, Xiu Ying,Pai, Sung Jin,Han, Sang Soo American Chemical Society 2017 JOURNAL OF PHYSICAL CHEMISTRY C - Vol.121 No.13

        <P>Molecular dynamics (MD) simulations using the reactive force field (ReaxFF) have been performed to elucidate the underlying water-induced disruption mechanism of several prototypical interpenetrated MOFs (IRMOF-9, IRMOF-13, and SUMOF4). Through the comparison to the corresponding noninterpenetrated MOFs (IRMOF-10 and IRMOF-14), for both the interpenetrated and noninterpenetrated MOFs, structural collapse was always accompanied by the dissociation of the water molecules, with the produced OH- and H+ forming chemical bonds with the Zn2+ ion and O atom of the ligand, respectively. However, the water stability of the interpenetrated MOFs is less than that of the corresponding noninterpenetrated structures. The reasons for the differences between the MOFs in the resistance to water attack are clarified. The water resistance of the noninterpenetrated MOFs is mainly attributed to the strength of the Zn-O-ligand, but, the hydrogen bond has little effect. However, a trade-off between the strength of the Zn-O-ligand bond and the hydrogen bond determines the water stability of the interpenetrated MOFs. We expect that our understanding of the water-disruption mechanisms of MOFs will provide helpful guidance for the design of MOFs with a high water-resistance. Additionally, this work shows that ReaxFF simulations could be a useful technique for predicting the hydrothermal stability of MOFs.</P>

      • Effect of Intraoperative Glucose Fluctuation and Postoperative IL-6, TNF-α, CRP Levels on the Short-term Prognosis of Patients with Intracranial Supratentorial Neoplasms

        Liu, Tie-Cheng,Liu, Qi-Ran,Huang, Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

        Objective: To investigate the effect of intraoperative glucose fluctuation and postoperative interlukin-6 (IL-6), tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), C-reactive protein (CRP) levels on the short-term prognosis of patients with intracranial supratentorial neoplasms. Materials and Methods: Eighty-six patients undergoing intracranial excision were selected in The Second Hospital of Jilin University. According to the condition of glucose fluctuation, the patients were divided into group A (glucose fluctuation <2.2 mmol/L, n=57) and group B (glucose fluctuation ${\geq}2.2mmol/L$, n=29). Glucose was assessed by drawing 2 mL blood from internal jugular vein in two groups in the following time points, namely fasting blood glucose 1 d before operation ($T_0$), 5 min after anesthesia induction ($T_1$), intraoperative peak glucose ($T_2$), intraoperative lowest glucose ($T_3$), 5 min after closing the skull ($T_4$), immediately after returning to intensive care unit (ICU) ($T_5$) and 2 h after returning to ICU ($T_6$). 1 d before operation and 1, 3 and 6 d after operation, serum IL-6 and TNF-${\alpha}$ levels were detected with enzyme-linked immunosorbent assay (ELISA), and CRP level with immunoturbidimetry. Additionally, postoperative adverse reactions were monitored. Results: There was no statistical significance between two groups regarding the operation time, anesthesia time, amount of intraoperative bleeding and blood transfusion (P>0.05). The glucose levels in both groups at $T_1{\sim}T_6$ went up conspicuously compared with that at $T_0$ (P<0.01), and those in group B at $T_2$, $T_4$, $T_5$ and $T_6$ were significantly higher than in group A (P<0.01). Serum IL-6, TNF-${\alpha}$ and CRP levels in both groups 1, 3 and 6 d after operation increased markedly compared with 1 d before operation (P<0.01), but the increased range in group A was notably lower than in group B (P<0.05 or P<0.01). Postoperative incidences of hypoglycemia, hyperglycemia and myocardial ischemia in group A were significantly lower than in group B (P<0.05), and respiratory support time obviously shorter than in group B (P<0.01). Conclusions: The glucose fluctuation of patients undergoing intracranial excision is related to postoperative IL-6, TNF-${\alpha}$ and CRP levels and those with small range of glucose fluctuation have better prognosis.

      • KCI등재

        Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment

        Ying Xing,Jie Ming,Tao Liu,Nana Zhang,Dingjun Zha,Ying Lin 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.9

        Purpose: Previous reports have shown that hyperglycemia-induced inhibition of transient receptor potential vanilloid sub type 4 (TRPV4), a transient receptor potential ion channel, affects the severity of hearing impairment (HI). In this study, we explored the role of TRPV4 in HI using HEI-OC1 cells exposed to high glucose (HG). Materials and Methods: HEI-OC1 cells were cultured in a HG environment (25 mM D-glucose) for 48 hours, and qRT-PCR and Western blotting were used to analyze the expression of TRPV4 at the mRNA and protein level. TRPV4 agonist (GSK1016790A) or antagonist (HC-067047) in cultured HEI-OC1 cells was used to obtain abnormal TRPV4 expression. Functional TRPV4 activity was assessed in cultured HEI-OC1 cells using the MTT assay and a cell death detection ELISA. Results: TRPV4 agonists exerted protective effects against HG-induced HI, as evidenced by increased MTT levels and inhibition of apoptosis in HEI-OC1 cells. TRPV4 overexpression significantly increased protein levels of phosphorylated p38 mitogen-activatedprotein kinase (p-p38 MAPK), while TRPV4 antagonists had the opposite effect. Our results indicated that TRPV4 is a hyperglycemia-related factor that can inhibit cell proliferation and promote cell apoptosis by activating the MAPK signaling pathwayin HEI-OC1 cells. Conclusion: Our results show that the overexpression of TRPV4 can attenuate cell death in HEI-OC1 cells exposed to HG.

      • KCI등재

        Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions

        Ying-Xiao Fu,Jian-Hong Gu,Yi-Ran Zhang,Xi-Shuai Tong,Hong-Yan Zhao,Yan Yuan,Xue-Zhong Liu,Jian-Chun Bian,Zong-Ping Liu 대한수의학회 2013 Journal of Veterinary Science Vol.14 No.4

        The purpose of this study was to determine whether osteoprotegerin (OPG) could affect osteoclat differentiation and activation under serum-free conditions. Both duck embryo bone marrow cells and RAW264.7 cells were incubated with macrophage colony stimulatory factor (M-CSF) and receptor activator for nuclear factor κB ligand (RANKL) in serum-free medium to promote osteoclastogenesis. During cultivation, 0,10, 20, 50, and 100 ng/mL OPG were added to various groups of cells. Osteoclast differentiation and activation were monitored via tartrate-resistant acid phosphatase (TRAP) staining,filamentous-actin rings analysis, and a bone resorption assay. Furthermore, the expression osteoclast-related genes, such as TRAP and receptor activator for nuclear factor κB (RANK),that was influenced by OPG in RAW264.7 cells was examined using real-time polymerase chain reaction. In summary,findings from the present study suggested that M-CSF with RANKL can promote osteoclast differentiation and activation,and enhance the expression of TRAP and RANK mRNA in osteoclasts. In contrast, OPG inhibited these activities under serum-free conditions.

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