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Kim, Kyungsook,Kim, Min-Jung,Kim, Minkyeong,Ju, Sejin,Song, Eun-Jee IGI Global 2018 International journal of e-health and medical comm Vol.9 No.4
<P>The purpose of this article was to examine the effects of multicultural adolescents' trauma and hopelessness on problem behaviors. The research subjects consisted of 108 adolescents (boys = 54, girls = 54 from multicultural families. They were adolescents aged between 12 and 20. The measures of the current study include scales for assessing adolescents' trauma, hopelessness, and problem behaviors. The data was analyzed using Pearson correlations, SPSS 21.0 program and AMOS 18.0 Structural Equation Modeling (SEM). Results demonstrated that multicultural adolescents' trauma, hopelessness, and problem behaviors were significantly correlated. Also, trauma had an indirect effect through hopelessness, as well as a direct effect on problem behaviors of adolescents. The importance of adolescents' cognition was identified on problem behaviors.</P>
Kim, Sung-Ryul,Yang, Jung-Il,Moon, Sunok,Ryu, Choong-Hwan,An, Kyungsook,Kim, Kyung-Me,Yim, Jieun,An, Gynheung Blackwell Publishing Ltd 2009 The Plant journal Vol.59 No.5
<P>Summary</P><P>RNA editing is the alteration of RNA sequences via insertion, deletion and conversion of nucleotides. In flowering plants, specific cytidine residues of RNA transcribed from organellar genomes are converted into uridines. Approximately 35 editing sites are present in the chloroplasts of higher plants; six pentatricopeptide repeat genes involved in RNA editing have been identified in Arabidopsis. However, although approximately 500 editing sites are found in mitochondrial RNAs of flowering plants, only one gene in Arabidopsis has been reported to be involved in such editing. Here, we identified rice mutants that are defective in seven specific RNA editing sites on five mitochondrial transcripts. Their various phenotypes include delayed seed germination, retarded growth, dwarfism and sterility. Mutant seeds from heterozygous plants are opaque. This mutation, named <I>opaque and growth retardation 1</I> (<I>ogr1</I>), was generated by T-DNA insertion into a gene that encodes a pentatricopeptide repeat protein containing the DYW motif. The OGR1–sGFP fusion protein is localized to mitochondria. Ectopic expression of <I>OGR1</I> in the mutant complements the altered phenotypes. We conclude that OGR1 is essential for RNA editing in rice mitochondria and is required for normal growth and development.</P>
Autophagy Stimulation Upregulated Collagen Synthesis in Cultured Human Fibroblast
( Kyungsook Yoo ),( Jiyeon Park ),( Sungwoo Kim ),( Jongmi Lim ),( Heijin Song ),( Hyunjung Kim ),( Sekyoo Jeong ) 한국피부장벽학회 2016 한국피부장벽학회지 Vol.18 No.2
Autophagy can be defined as a self-digestive process, targeting internal or damaged organelles and misfolded proteins to lysosomal degradation. While its major role is a survival mechanism under stress conditions, such as nutrient restriction, it can also affect various cellular responses including inflammation, aging, and immune responses. Along with the clinical implications in various human diseases, such as neurodegenerative diseases, infection, and cancer, recent reports also suggested the potential involvement of autophagy in skin aging. In order to investigate the roles of autophagy in skin physiology, amino acid based chemical library was established and potential autophagy stimulating compounds were identified by measuring autophagic vacuole formation in cultured human fibroblast. Upregulation of autophgic flux by screened compounds were further investigated by measuring p62 and LC3-II expressions. Electron microscopic observation was also performed for observing the morphologic changes in cells. Among the screened compounds, S8_049, and S9_067 showed significant stimulating activities in cultured human skin fibroblast. In order to investigate the potential anti-aging effects of the selected compounds, expression of collagen and MMPs were also measured in cultured fibroblasts. As results, increased expression of collagen I was observed in S8_049 treated cells. Full thickness 3D culture model experiments also confirmed the increased expression of collagens in dermal layer in S8_049 treated tissue. Microarray experiments showed the increased expression of several sphingolipids synthesis and degrading enzymes, which suggested that the changes of intracellular sphingolipids levels might be, at least in part, underlying mechanism of autophagy stimulation.
Kim, Soo-Jin,Lee, Sang-Choon,Hong, Soon Kwan,An, Kyungsook,An, Gynheung,Kim, Seong-Ryong Springer-Verlag 2009 Molecules and cells Vol.27 No.4
<P>The OsAsrt cDNA clone was isolated from a cDNA library prepared from developing seed coats of rice (Oryza sativa L.). Low-temperature stress increased mRNA levels of OsAsr1 in both vegetative and reproductive organs. In situ analysis showed that OsAsr1 transcript was preferentially accumulated in the leaf mesophyll tissues and parenchyma cells of the palea and lemma. For transgenic rice plants that over-expressed full-length OsAsr1 cDNA in the sense orientation, the Fv/Fm values for photosynthetic efficiency were about 2-fold higher than those of wild type-segregating plants after a 24-h cold treatment. Seedlings exposed to prolonged low temperatures were more tolerant of cold stress, as demonstrated during wilting and regrowth tests. Interestingly, OsAsr1 was highly expressed in transgenic rice plants expressing the C-repeat/dehyhdration responsive element binding factor 1 (CBF1), suggesting the regulation of OsAsr1 by CBF1. Taken together, we suggest that OsAsr1 gene play an important role during temperature stress, and that this gene can be used for generating plants with enhanced cold tolerance.</P>
김경숙(Kim, Kyungsook) 언어과학회 2014 언어과학연구 Vol.0 No.71
This study investigates the usage of Korean color terms ``phalan`` and ``phuleun``. As in Chinese and Japanese, Korean indigenous color terms have been claimed to have no distinction between green and blue. Hence, the color that encompasses green and blue is often referred to as grue which amounts to a blend of green and blue. The study analyzes collocation patterns of ``phalan`` and ``phuleun`` on the one hand and perception patterns on the 24-color wheel on the other, by young-male, young-female, old-male, and old-female groups. It is argued that ``phalan`` was initially developed as a focal color of ``phuleun`` in the past and that more recently ``phalan`` came to be used for blue while ``phuleun`` has remained the same. Now, it seems that the younger generation begin to treat ``phalan`` as a new basic color term for blue while retaining ``phuleun`` as grue with its focal color being ``cholok``, which has the meaning of green. As a result, there are by now six, not five, basic color terms in Korean: black, white, red, yellow, blue, and green. The suggested change in the basic color system remains to be further verified in the coming years.