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A Study on Innovation in Technology and Design Variation for Super Tall Buildings
Kim, Hyeong-Il,Shin, Sungwoo Architectural Institute of Japan 2011 JOURNAL OF ASIAN ARCHITECTURE AND BUILDING ENGINEE Vol.10 No.1
<P>The paper presented Design Variation and Technology for Super Tall Buildings, the topic presented in the 12th International Symposium of Korea Super Tall Building Forum by Hyeong-il Kim. In this paper, author review examples of technological innovations in tall building design, illustrating the interaction between architectural form and design tools. It also traces current approaches in architectural form generation and possible design solutions. It is a multidisciplinary problem and an integrated work that involves engineering, architecture, state-of-art construction technology and digital design tools. The study will show a clear linkage of generative design encouraged by technological innovations to design problems in tall building design practice, in addition to its diversely effected results by computerized design tools and construction using CAD/CAM technology.</P>
Kim, Sungwoo,Kim, Taehoon,Im, Sang Hyuk,Seok, Sang Il,Kim, Kang Wook,Kim, Sungjee,Kim, Sang-Wook Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.39
<P>Bandgap-engineered monodisperse HgTe NCs of different sizes were synthesized by means of a facile temperature-control method, a non-aqueous and non-Te-gas process. The photo-physical properties of the synthesized NCs in a simple photovoltaic device were tested. It was shown that this cell is capable of processing signals up to the 100 kHz level below 3 dB and hence is suitable for use in NIR photodetection.</P> <P>Graphic Abstract</P><P>Bandgap-engineered monodisperse HgTe NCs were synthesized by temperature-control method, a non-aqueous and non-Te-gas process. The NCs were tested in a simple photovoltaic device, which showed that this cell is capable of processing signals up to the 100 kHz level below 3 dB. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm12436f'> </P>
Fate of Astrocytes in The Gerbil Hippocampus After Transient Global Cerebral Ischemia
Kim, Hyeyoung,Park, Joon Ha,Shin, Myoung Cheol,Cho, Jun Hwi,Lee, Tae-Kyeong,Kim, Hyunjung,Song, Minah,Park, Cheol Woo,Park, Young Eun,Lee, Jae-Chul,Ryoo, Sungwoo,Kim, Young-Myeong,Kim, Dae Won,Hwang, MDPI 2019 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.20 No.4
<P>Neuronal death and reactive gliosis are major features of brain tissue damage following transient global cerebral ischemia (tgCI). This study investigated long-term changes in neuronal death and astrogliosis in the gerbil hippocampus for 180 days after 5 min of tgCI. A massive loss of pyramidal neurons was found in the hippocampal CA1 area (CA1) area between 5 and 30 days after tgCI by Fluoro-Jade B (FJB, a marker for neuronal degeneration) histofluorescence staining, but pyramidal neurons in the CA2/3 area did not die. The reaction of astrocytes (astrogliosis) was examined by glial fibrillary acidic protein (GFAP) immunohistochemistry. Morphological change or degeneration (death) of the astrocytes was found in the CA1 area after tgCI, but, in the CA2/3 area, astrogliosis was hardly shown. GFAP immunoreactive astrocytes in the CA1 area was significantly increased in number with time and peaked at 30 days after tgCI, and they began to be degenerated or dead from 40 days after tgCI. The effect was examined by double immunofluorescence staining for FJB and GFAP. The number of FJB/GFAP<SUP>+</SUP> cells (degenerating astrocytes) was gradually increased with time after tgCI. At 180 days after tgCI, FJB/GFAP<SUP>+</SUP> cells were significantly decreased, but FJB<SUP>+</SUP> cells (dead astrocytes) were significantly increased. In brief, 5 min of tgCI induced a progressive degeneration of CA1 pyramidal neurons from 5 until 30 days with an increase of reactive astrocytes, and, thereafter, astrocytes were degenerated with time and dead at later times. This phenomenon might be shown due to the death of neurons.</P>
Kim, Sungwoo,Kang, Meejae,Kim, Seajin,Heo, Jin-Hyuk,Noh, Jun Hong,Im, Sang Hyuk,Seok, Sang Il,Kim, Sang-Wook American Chemical Society 2013 ACS NANO Vol.7 No.6
<P>We report the first synthesis of colloidal CuInTe<SUB>2</SUB>, CuInTe<SUB>2–<I>x</I></SUB>Se<SUB><I>x</I></SUB> gradient alloyed quantum dots (QDs) through a simple hot injection method. We confirmed the composition of synthesized QDs to cationic rich phase of CuIn<SUB>1.5</SUB>Te<SUB>2.5</SUB> and Cu<SUB>0.23</SUB>In<SUB>0.36</SUB>Te<SUB>0.19</SUB>Se<SUB>0.22</SUB> with XPS and ICP analysis, and we have also found that the gradient alloyed Cu<SUB>0.23</SUB>In<SUB>0.36</SUB>Te<SUB>0.19</SUB>Se<SUB>0.22</SUB> QDs exhibit greatly improved stability over the CuIn<SUB>1.5</SUB>Te<SUB>2.5</SUB> QDs. The solution-processed solar cell based on the gradient alloyed Cu<SUB>0.23</SUB>In<SUB>0.36</SUB>Te<SUB>0.19</SUB>Se<SUB>0.22</SUB> QDs exhibited 17.4 mA/cm<SUP>2</SUP> of short circuit current density (<I>J</I><SUB>sc</SUB>), 0.40 V of open circuit voltage (<I>V</I><SUB>oc</SUB>), 44.1% of fill factor (FF), and 3.1% of overall power conversion efficiency at 100 mW/cm<SUP>2</SUP> AM 1.5G illumination.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-6/nn401274e/production/images/medium/nn-2013-01274e_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn401274e'>ACS Electronic Supporting Info</A></P>
Kim, Suji,Lee, Kyu-Sun,Choi, Seunghwan,Kim, Joohwan,Lee, Dong-Keon,Park, Minsik,Park, Wonjin,Kim, Tae-Hoon,Hwang, Jong Yun,Won, Moo-Ho,Lee, Hansoo,Ryoo, Sungwoo,Ha, Kwon-Soo,Kwon, Young-Guen,Kim, Youn American Society for Biochemistry and Molecular Bi 2018 The Journal of biological chemistry Vol.293 No.49
<P>Inflammatory cytokines, including tumor necrosis factor-α (TNFα), were elevated in patients with cardiovascular diseases and are also considered as crucial factors in the pathogenesis of preeclampsia; however, the underlying pathogenic mechanism has not been clearly elucidated. This study provides novel evidence that TNFα leads to endothelial dysfunction associated with hypertension and vascular remodeling in preeclampsia through down-regulation of endothelial nitric-oxide synthase (eNOS) by NF-κB–dependent biogenesis of microRNA (miR)-31-5p, which targets eNOS mRNA. In this study, we found that miR-31-5p was up-regulated in sera from patients with preeclampsia and in human endothelial cells treated with TNFα. TNFα-mediated induction of miR-31-5p was blocked by an NF-κB inhibitor and NF-κB p65 knockdown but not by mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase inhibitors, indicating that NF-κB is essential for biogenesis of miR-31-5p. The treatment of human endothelial cells with TNFα or miR-31-5p mimics decreased endothelial nitric-oxide synthase (eNOS) mRNA stability without affecting <I>eNOS</I> promoter activity, resulting in inhibition of eNOS expression and NO/cGMP production through blocking of the functional activity of the eNOS mRNA 3′-UTR. Moreover, TNFα and miR-31-5p mimic evoked endothelial dysfunction associated with defects in angiogenesis, trophoblastic invasion, and vasorelaxation in an <I>ex vivo</I> cultured model of human placental arterial vessels, which are typical features of preeclampsia. These results suggest that NF-κB–responsive miR-31-5p elicits endothelial dysfunction, hypertension, and vascular remodeling via post-transcriptional down-regulation of eNOS and is a molecular risk factor in the pathogenesis and development of preeclampsia.</P>
Registrational setbacks in Insecticide Items failed in Reviews
Sungwoo Kim,Young-lim Kim,In-Young Lee,Jae-eup Park 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05
In pesticide registration, the most of applicants are manufacturing companies which have richly experience in applying registration. With their experience, registration applications of pesticide shows excellent ratio of pass, but still some of application still fail to pass, and are judged as disqualifications or to be returned for supplement. In 2009, There were 6 items failed in registrational reviews. Two of them were for their active ingredient contents lower than specifications, Other two were for trials conducted wrong, so sent back to applicants to add supplement. But the rest of them, two items showed low efficiency in one trial, and were judged as disqualifications, which mean that ingredient cannot be registered for that target crop forever. Disqualification from low efficiency has highly strict criterion and usually don't have any flexibility to lower efficiency than criteria, unless there was no pesticide available for that pest. The way to remedy this criterion is very delicate and controversial issue, and needs more reconciliation of various views.
Kim, Dae Hun,Lee, Young Hun,Lee, Dea Uk,Kim, Tae Whan,Kim, Sungwoo,Kim, Sang Wook Optical Society of America 2012 Optics express Vol.20 No.10
<P>High-efficiency organic photovoltaic (OPV) cells utilizing a poly(3-hexylthiophene) (P3HT) pillar layer containing ZnSe quantum dots (QDs) were fabricated by using a mixed solution method. Scanning electron microscopy and high-resolution transmission electron microscopy images showed that the ZnSe QDs were dispersed in the P3HT layer. The power conversion efficiency of the OPV cells with a P3HT pillar layer containing ZnSe QDs was as much as 100% higher than that of the OPV cells with a planar layer due to an enhancement of the photon-harvesting ability of the congregated P3HT particles containing ZnSe QDs and to an increase of the interfacial region for efficient charge transport.</P>
Kim, Do Hyun,Hong, Yong-Kil,Jeun, Sin-Soo,Park, Yong Jin,Kim, Soo Whan,Cho, Jin Hee,Kim, Boo Young,Han, Sungwoo,Jung, Young Hoon,Lee, Yong Joo,Kim, Sung Won SAGE Publications 2016 Otolaryngology-head and neck surgery Vol.154 No.6
<P>Objective We evaluated postoperative changes in nasal cavity dimensions and their effects on nasal functions and symptoms. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods We studied patients who underwent binostril, 4-hand endoscopic endonasal transsphenoidal approach surgery with the bilateral modified nasoseptal rescue flap technique. Pre- and postoperative paranasal computed tomography scans were used to assess nasal cavity dimensional changes at 4 levels. We also performed several pre- and postoperative tests, including the Connecticut Chemosensory Clinical Research Center test and the Cross-Cultural Smell Identification Test (n = 119) to evaluate olfactory functions. Also, the Nasal Obstruction Symptoms Evaluation, the Sino-Nasal Outcome Test-20, and a visual analog scale were used (n = 157) to record subjective symptoms. We compared these data with the pre- and postoperative nasal cavity dimensions. Results Two-dimensional objective increases in nasal passage dimensions were evident postoperatively (all cross-sectional areas, P < .001, except choana and left inferior turbinate). However, these did not correlate with subjectively assessed symptoms (Nasal Obstruction Symptoms Evaluation, all cross-sectional areas, P .05, except right middle turbinate; Sino-Nasal Outcome Test-20, all cross-sectional areas, P .05) or olfactory dysfunction evaluated with the Connecticut Chemosensory Clinical Research Center test (all cross-sectional areas, P .05) or the Cross-Cultural Smell Identification Test (all cross-sectional areas, P .05). Conclusion Endoscopic endonasal transsphenoidal approach surgery altered the patients' nasal anatomy, but the changes in nasal cavity dimensions did not affect nasal functions and symptoms. These results will help surgeons to appropriately expose the surgical field during endoscopic endonasal transsphenoidal approach surgery.</P>
Highly Luminescent InP/GaP/ZnSNanocrystals and TheirApplication to White Light-Emitting Diodes
Kim, Sungwoo,Kim, Taehoon,Kang, Meejae,Kwak, SeongKwon,Yoo, Tae Wook,Park, Lee Soon,Yang, Ilseung,Hwang, Sunjin,Lee, Jung Eun,Kim, Seong Keun,Kim, Sang-Wook American Chemical Society 2012 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.134 No.8
<P>Highly stable and luminescent InP/GaP/ZnS QDs with a maximum quantum yield of 85% were synthesized by in situ method. The GaP shell rendered passivation of the surface and removed the traps. TCSPC data showed an evidence for the GaP shell. InP/GaP/ZnS QDs show better stability than InP/ZnS. We studied the optical properties of white QD-LEDs corresponding to various QD concentrations. Among various concentrations, the white QD-LEDs with 0.5 mL of QDs exhibited a luminous efficiency of 54.71 lm/W, Ra of 80.56, and CCT of 7864 K.</P>