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      • KCI등재

        폐부종과 심정지가 발생한 페노바비탈 중독환자

        오동렬,이운정,박규남,김세경,김영민,이환,유은영,최경호,정시경 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

        Phenobarbital is a long-acting barbiturate causing generalized depression of neuronal activity in the brain. Its effect is primarily achieved through enhanced GABA-mediated synaptic inhibition. Its use as an antiepileptic agent was first described in 1912. Before the introduction of phenytoin, phenobarbital is used as sedative-hypnotics. It is used for the treatment of epilepsy and status epilepticus. All barbiturates, including phenobarbital, have a high potential for abuse. They were frequently used for suicide attempts in the past, but they have in large part been replaced by benzodiazepines. The onset of symptoms depends on the drug and the route of administration. Mild to moderate barbiturate intoxication resembles ethanol inebriation with slurred speech, ataxia, and lethargy. Severe acute barbiturate intoxication is life threatening. Early deaths are generally cardiovascular-related. Hypotension, shock, pulmonary edema, and cardiac arrest that occurs with large doses are caused by depression of central sympathetic tone and as well as by direct depression of cardiac contractility. The potentially fatal oral dose of phenobarbital is 6-10g. We describe an 23-year-old woman with pulmonary edema, and cardiac arrest ingestion of 18grams of phenobarbital. She was completely recovered by successful cardiopulmonary resuscitation and homoperfusion. We report a case with literature review.

      • 슬개골 골절과 동반된 후방 십자인대 손상

        오정환,신규철 건국대학교 의과학연구소 1994 건국의과학학술지 Vol.4 No.-

        Patellar fractures result from direct and/or indirect forces. The majority of the patellar fractures result from direct injuries and a fall on the knee or a direct blow sustained in the vehicular trauma is one of the common causes. Patellar fractures from indirect forces occur when the intrinsic strength of the patella is exceeded by the pull of the musculotendinous and ligamentous units attaching to it and typically occurs in the act of stumbling or partially falling. Posterior cruciate ligament disruption is generally caused by a posteriorly directed force on the proximal tibia, and hyperextension with abduction or external rotation movements have been also described in the production of posterior cruciate ligament injuries. Posterior cruciate ligament injuries are apt to be negelected frequently, and ipsilateral femoral shaft fracture or posterior dislocation of the hip also may be seen with direct injuries to the patella, but patellar fractures are rarely associated with posterior cruciate ligament injuries. So we are reporting four cases of the posterior cruciate ligament injuries as one of the combined entity, which had been neglected and associated with the patellar fracture after a review of the literatures.

      • KCI등재

        抗精神病藥物에 依한 無顆粒細胞症 治驗 1例

        吳東財,申榮宇,張煥一,趙京杉,朴康圭 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.1

        The authors experienced a female schizophrenic patient who revealed severely decreased leucocytes (350/㎣) with the manifestation of high fever, chillness and sore throat after the oral administration of neuroleptics. Agranulocytosis induced with the use of neuroleptic drugs has been well known complication in psychiatric practice although it is quite rare. In this case, following the combined use of neuroleptics (thioridazine halopondol and chlorproonazine), severe decrement of leucocytes (mainly lymphocytes with few neutrophils) was noticed on peripheral blood and marked decrement of erythroid series, especially of myeloid series, with decrement of total cellular elements were confirmed through the biopsy of bone marrow. She did not responded at all to the massive administration of antibiotics, but dramatic improvement was noticed both clinically and in the follow-up biopsy findings of bone marrow after two times trial of leukapheresis.

      • 경피적 강선고정을 이용한 요골 원위부 관절내 분쇄골절의 치료

        안의환,오정환,신규철 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

        From March 1991 to August 1995, twenty-eight cases of intraarticular comminuted distal radius fractures were treated by percutaneous pinning with closed reduction under fluoroscopy. From all cases, twenty two fractures(79%) were healed satisfactorily with no special problems. But in cases of fractures showing severe comminution or osteoporosis, the result was not good. We conclude that percutaneous pin fixation is an excellent technique for an unstable fractures in combination with external immobilization, provided the distal radius is not severly comminuted or osteoporotic.

      • 금강 수서생태계의 구조와 기능에 관한 연구 : 수질 및 미생물

        이규승,김윤석,오덕환,이영하,임항식 忠南大學校 環境問題硏究所 1995 環境硏究 Vol.13 No.-

        소백산맥의 주봉인 덕유산에서 발원하여 군산지역에서 황해로 유입되는 금강의 본류는 총 유로연장이 401.4km에 이르는 우리나라 4대강 중의 하나이며, 대전광역시, 충청남북도 및 전라북도 일부지역의 생활용수 및 산업용수의 공급원으로서 대단히 중요한 역할을 담당하고 있다. 1960년대 이후 계속적으로 추진된 경제개발과 공업화 정책에 의해 인구의 도시집중화, 생활수준의 향상등이 이루어지고, 이에 따라 양질의 생활용수 및 산업용수에 대한 수요는 계속적으로 크게 증가하고 있는 실정이다. 그러나 금강의 경우 도시의 생활하수, 공업단지로부터의 공업폐수, 유역의 축산폐수 등에 의해 수질을 비롯한 수환경의 악화가 점차 심화되고 있으며, 이에 따른 수서생태계의 변화도 매우 큰 것으로 보고되고 있다. 특히 최근에 조성된 바 있는 금강 하구둑이 94년 8월부터 가동되고 있고, 또 1995년 이후 금강종합개발이 중류와 하류지역을 중심으로 대대적으로 시행될 예정이어서 금강 본류의 수환경은 장차 많은 변화가 예상된다. 수환경의 변화는 생육하는 생물들의 종조성은 물론 군집의 구조와 기능에 큰 영향을 미치기 때문에 금강 본류의 수서생태계에도 많은 변화가 수반될 것으로 예측되고 있다. 이와 같이 금강본류를 대상으로 하는 사업이 시행된 후 야기되는 수환경의 변화는 장기간에 걸친 조사를 요구하며, 이로부터 얻은 결과를 사업 시행 이전의 조사 결과와 비교함으로써만이 효과적으로 그 경향을 파악할 수 있다. 또한 이러한 비교 분석은 수질관리를 위한 대책 수립과 효율적인 사후 환경관리를 모색하는데 대단히 중요하다. 이에 반하여 지금까지 금강을 대상으로 한 수환경 및 수서생태계의 조사 연구는 단편적인 분야에 대하여 극히 단기간 수행된 것이 대부분이고 정량분석이 아닌 정성분석에만 치중되었기 때문에 금강의 수질 및 생태게보존을 위한 자료로서의 기능을 발휘하지 못하고 있다. 이러한 관점에서 본 환경문제연구소에서는 장기(향후 5년 이상)적인 계획하에 금강본류를 대상으로 수서생태계의 구조와 기능을 조사ㆍ분석하고, 이를 통하여 금강의 수질 및 생태계보존과 수환경관리를 위한 기초자료를 수립하고자 한다. 이와 같이 본 환경문제연구소가 장기적으로 추진하려 하는 금강 수서생태계학술조사는 금강 수서생태계의 현황은 물론 금강을 대상으로 하는 여러가지 형태의 사업에 의한 변화 양상을 정확하게 파악하고, 이에 대한 적절한 대처 방안을 강구하게 할 수 있는 기초자료를 제공하여 줄 것으로 기대된다. 지금까지 금강에 대한 종합적인 생태계 조사가 이루어지지 않고 있음을 고려할 때, 본 학술조사는 장차 금강 수서생태계에 대한 연구의 지침이 될 것으로 기대되며, 이는 본교가 금강 생태계의 보존과 관리를 통하여 지역사회에 기여하는 중추적 학술기관으로서의 위치를 확고히 마련하는 계기가 될 것이다. 본 보고서는 이러한 연구계획의 1차년도 연구결과로서 수질 및 미생물, 수생식물, 어류, 동식물 플랭크톤, 수서곤충을 중심으로 금강 중ㆍ하류 유역 수서생태계를 구성하고 있는 주요 생물군의 구조와 기능을 정량적으로 조사ㆍ분석하는데 그 목적을 두었다. Heterotrophic microbial populations and physicochemical parameters of water samples collected from six stations on the Keum River have been examined from November 1994 to July 1995. The ranges for BOD and COD were 1.5-11.3㎎/L and 2.1-13.7㎎/L, respectively. At the station closest to the estuary, the values of BOD and COD were higher than at other stations, but those of PO₄-P were lower. Metal ions including Cu, Mn, Pb, Cd, and Hg were not detected at all. The population densities of heterotrophic bacteria amounted to 13.7-22.0% of the total bacteria. The densities of coliforms, Salmonella-Shigella, and yeasts were in the range of 49-538 cfu/ml, 16-271 cfu/100ml, and 30-259 cfu/㎖, respectively.

      • 金屬薄膜導波管을 利用한 I/O Mode Filter

        박한규,오한솔,김명수 연세대학교 산업기술연구소 1981 논문집 Vol.13 No.2

        代表的인 3종류의 金屬薄膜導波管의 TEo-Mode와 TMo-Mode의 특성을 Computer Simulation에 의하여 비교 고찰하였다. 非對稱型平板薄膜導波管으로된 금속박막도파관은 TEo-Mode Filtering이 不可能하였다. 對稱型平板薄膜導波管으로된 금속박막도파관에서는 Film층과 그 외의 층과 굴절율 차이가 0.02 이하가 되면 TEo-Mode Filtering이 가능하며 TMo-Mode 의 損失이 10dB/cm이하가 되어 Mode Filter로서 使用可能함이 밝혀졌다. The typical three kinds of the Metal-Clad waveguides have been chosen, and the characteristics of TEo-Mode and TMo-Mode in them are investigated and compared with each other by computer simulation. TEo-Mode filtering has been impossible in the Metal-Clad waveguide made of the symmetric thin film slab waveguide. In the Metal-Clad waveguide made of the symmetric thin film slab waveguide, if the refraction index difference between the film layer and the other layers is below 0.02, it has made TEo-Mode filtering possible and has had TMo-Mode loss below 10dB/㎝. Therefore it has been improved that it can be used practically as a Mode Filter.

      • 대학생의 여가활동에 관한 연구

        이규동,오현환 建國大學校 敎育硏究所 1993 論文集 Vol.17 No.-

        The purpose of this study was to observe and analyze the recreational activities of the college students in terms of finding some possible ways to lead them into a sound, positive living mode. For this purpose, a total of 300 college students - 150 male and 150 female evenly- were given the questionnaire on which how to spend their leisure time was asked. The result is as follows : 1) According to the feedback, most collegian have the leisure times from 3 to 5 hours a day. 2) In a time-free from school classes, the 10% of them is engaged in some physical activities, which consists of the 3% for soccer, the 1.7% for pingpong and tennis, the 1.3% for basketball, and the 1% baseball. 3) The 14.3 precent of the total numbers spends their leisure times after all the classes are over in some physical activities. The 3.7% of the given percentage are playing tennis, the 2.7% playing soccer, the 2.3% going to health club, and the 2% pingpong. 4) A 17% of the percentage consists of those who are devoted to some physical activities for the recreation of the holidays and the weekends. Of the 17%, a 3.7% climbs mountain, a 3.3% is engaged in playing tennis, 2% in pingpong and health club, 1.7% in rope-skipping, and 1.7% in swimming. 5) Their attitudes toward the sport game in the leisure time were very serious to a degree of fighting to the last. 6) Most students tend to avoid having their physical activities early in the morning : therefore, it is necessary to encourage them to do physical activities in the morning. 7) Most of those who don't make use of their leisure time for doing something physical tend to spend their time in their home watching some sport game on T. V. rather than directly going to playing ground to see it because a number of broadcasting T. V. stations hookup a number of sport games.

      • KCI등재

        最近 8年間의 精神神經科 入院 外來 및 患者에 對한 統計的 考察(1960年∼1967年)

        李哲奎,盧英一,張煥一,金明源,任允明,韓東洙,吳承煥,金光日 大韓神經精神醫學會 1969 신경정신의학 Vol.8 No.1

        1) The number of the out-and in-patients had increased year after year (Table Ⅰ & Ⅲ). 2) Schizophrenia was the greatest number of the in-patients and its rate to whole was 49.1 percent, and neurosis was the greatest number of the out-patients and its rate to whole was 41.66 per cent (Table Ⅰ & Ⅶ). 3) In in-patients, hysteria revealed relatively large in percentage as 11.8% than the other groups (Table Ⅰ). 4) The rate of the male hysteria patients to all male patients was 3.5 per cent and the rate of female hysteria was 20.5 per cent (Table Ⅱ). 5) In in-patients, all the patients of general paresis and alcoholism were only males in sex(Table Ⅱ). 6) In in-patients of schizophrenia, the ratio of the male patients to the female patients was 57.0 : 43.0, but the each rate of each total numbers of the all diseases of the both sexes was almost same (Table Ⅲ). 7) The largest age group of the all patients was between 21∼30 years old, and the next was between 31∼40 years in in-patients (Table Ⅲ). 8) The largest age group of schizophrenia patients was between 21∼30 years and that of M.D.R patients was between 31∼40 years in in-patients (Table Ⅲ). 9) In in-patients of hysteria, the largest age group was between 31∼40 years, and the next was between 21∼30 years (Table Ⅲ). 10) The results of treatment in in-patients were as followings; Recovered; 27.6% Much improved; 43.1% Slightly improved and no changed; 28.2% (Table Ⅳ) 11) The results of treatment in schizophrenia of the in-patients were as followings; Recovered; 19.1% Much improved; 48.3% Slightly improved and no changed; 32.1% (Table Ⅴ) 12) The mode of treatment had been somewhat changed during last 8 years from 1960 to 1967 in treatment of the in-patients (Table Ⅵ). (1) The combined therapy of tranquilizers and EST had been increased, but the therapy of tranquilizer alone or EST alone had been decreased, compared to 1960. (2) The therapy of ICT in the treatment of in-patients had been much decreased.

      • 알레르기성 비염 환자에서 절지동물성 특이항원의 양성율 및 항원간 일치율

        황규윤,남해선,박준수,권준택,백병준,김장묵,오천환,조성란 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

        The current study was designed to evaluate the positive rates of arthropod allergens by Korean inhalant panel of MAST-CLA in patients with allergic rhinitis. One hundred sixty patients, diagnosed to allergic rhinitis in an Out Patient Center of Soonchunhyang University Chunan Hopsital during Aug 1998 to July 2000, were studied. 1. The overall positive rate among 35 specific allergens was 59.4% (95 patients). 2. The arthropod related allergen accounted for 82.1% (78 patients) of the positive rate. 3. Each positive rate of Dermatophagoides farinae (Df), Dermatophagoides pteronyssinus (Dp), house dust (Hd), and cockroach mix (Cm) was 45.0% (72 patients), 43.1% (69 patients), 28.1% (45 patients), and 8.8% (14 patients), respectively. 4.Significant agreement between arthropod allergens was observer (P < 0.05). 5. The obseved agreement between Df and Dp was 95.6%, showing most significant Kappa index (Kappa = 0.911, P < 0.001). There results suggested that although MAST-CLA is a useful measure of identifying specific allergens, the specificity of two mite allergen relatively low, implying because of common allergen between mites in Korean panel of MAST-CLA. Our data also supported that arthropod is the major cause of allergen in patients with allergic rhinitis, however, the MAST-CLA should be modified in order to exclude common allergen of mite and to include more specific mite allergen.

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