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이관호,한승세,이동협,김성숙,이현우,이정철,최교원,정진홍,서정일 영남대학교 의과대학 1993 Yeungnam University Journal of Medicine Vol.10 No.2
전형 중심성 기관지 유암종과 비전형 기관지유암종을 기관지내시경하 생검 및 전산화 단층촬영하 생검으로 확진했으며 근치적 치료로 폐절제술을 시행한 치험 2례를 문헌 고찰과 아울러 보고하는 바이다. Bronchial carcinoid tumor was a low grade malignant and it was regarded as predictable clinical course and good survivality after surgical resection. But despite of its low grade malignant potentiality, bronchial carcinoid tumor was clearly capable of metastasizing and causing death. We present 2 cases of bronchial carcinoid tumors. One of them was typical carcinoid tumor in 44 year-old female and another was atypical carcinoid tumor in 53 year-old male patient. Currative therapeutic procedure was performed by lobectomy and wedge resection.
Relationship of Renal Echogenicity with Renal Pathology and Function
Lee, Jin Hee,Cho, Myung Hyun,Chung, Sung Ill,Lim, So Dug,Kim, Kyo Sun Korean Society of Pediatric Nephrology 2017 Childhood kidney diseases Vol.21 No.2
Purpose: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known. Method: Ultrasound examination was performed in 75 patients undergoing renal biopsy for suspected renal disease in Konkuk University Medical Center from August 2005 to November 2015. We compared renal echogenicity to pathologic findings and renal function. Renal echogenicity was scored as 0 to 2 by comparing adjacent liver echogenicity. Three histologic characteristics were evaluated: glomerular changes, interstitial infiltration or fibrosis, and tubular atrophy. These were graded as 0 to 3, according to increasing severity. Laboratory results included urine albumin excretion and estimated glomerular filtration rate (eGFR). Results: Among pathologic findings, renal echogenicity revealed a positive correlation with interstitial infiltration or fibrosis (r=0.259, P=0.025), and with tubular atrophy (r=0.268, P=0.02). Renal echogenicity and glomerular changes were not correlated. Renal echogenicity showed a positive correlation with microalbuminuria (r=0.283, P=0.014), but a negative correlation with eGFR (r=-0.352, P=0.002). Conclusion: Increased renal echogenicity suggested severe interstitial infiltration or fibrosis and tubular atrophy among the pathologic findings. Moreover, increased echogenicity is correlated with increased urine albumin excretion and decreased eGFR. Echogenicity on ultrasonography is useful for determining the status of renal pathology and function.
Shift Characteristics Analysis and Smooth Shift for an Automatic Power Transmission
Jeong, Heon-Sul,Lee, Kyo-Ill The Korean Society of Mechanical Engineers 2000 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.14 No.5
Smooth shift is one of the key issues in automatic power transmission control systems. However, the torque sensors are too expensive to be used in shift controllers on production vehicles. In order to provide a basic strategy for smooth shifting by using RPM sensors only and in order to accomplish the shift within a designated time, this paper studies detailed characteristics of the smooth shift for clutch-to-clutch shift mechanism. A desired trajectory of slip speed is proposed for smooth acceleration shift defined in this paper. Also the clutch torque needed to achieve this trajectory is derived, and it may be used as a open loop shift control law.
Jeong, Heon-Sul,Lee, Kyo-Ill The Korean Society of Mechanical Engineers 2000 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.14 No.5
For shift quality improvement, torque sensors are currently too expensive to be used on production vehicles. To achieve smooth acceleration shift, the reference trajectory of the clutch slip speed for accomplishing the shift process within a designated shift completion time and its relationship with the clutch actuating torque were suggested by Jeong and Lee (1999). In order to facilitate the proposed algorithm, nonlinear estimators for necessary information such as the axle shaft torque, clutch friction and turbine torque were designed using only speed sensors. Accounting for the modeling error, a control law for this indirect smooth shift was proposed based on the above mentioned suggestions. Simulation results of the proposed estimators and shift controller were presented and further considerations for practical applications are discussed.
Kim, Min-Jung,Lee, Kyo-Young,Min, Kyung-Hee,Lee, Myeong-Sok,Cheon, Choong-Ill,Song, Eun-Sook 한국유전학회 2003 Genes & Genomics Vol.25 No.2
In vitro translation of cytochrome c oxidase on mitochondria of mouse tissues was compared with the level of mitochondrial DNA (mtDNA) deletion and of the transcript during aging. Translation activity of mitochondria from old testis declined considerably compared with old brain and liver. In the region of 12S rRNA and URF6L spanning COXⅢ gene locus, age-related mtDNA deletion was considerable and multiple ranging from 7.4 kb to 9.17 kb deletion in old brain and testis, but barely detectable in old liver. The transcript amount of subunit Ⅲ of cytochrome c oxidase decreased substantially in old testis, while being little reduced in brain and liver. Deletion, transcription and translation levels seemed to be related to testis during aging but not in brain. Especially deletion level was not related with age in brain and liver. Present observation from testis suggests that, among the gene mutation and gene expression steps, translational alteration may play a major role in irreversible aging process.
황체퇴화시 황체막 Na<sup>+</sup>-K<sup>+</sup>-ATPase 활성도의 변화
김인교(Kim, In-Kyo),연동수(Yeoun, Dong-Soo),이승일(Lee, Syng-Ill) 대한생리학회 1982 대한생리학회지 Vol.16 No.2
Slices of rat corpora lutea(CL) incubated with. prostaglandin F<sub>2α</sub>(PGF<sub>2α</sub>) in Krebs-Hensenleit (K-H) Ringer solution showed a decrease in Na<sup>+</sup>-K<sup>+</sup>-ATPase activity after 60 min of incubation. However, PGF<sub>2α</sub> in vitro did not alter Na<sup>+</sup>-K<sup>+</sup>-ATPase activity of isolated luteal membrane fractions. Following PGF<sub>2α</sub> induced in vivo luteal regression, reduction of Vmax an elevation of the activation energy above transition temperature of the lipid phase of the membrane occurred without changes of Km, optimum pH and transition temperature. These results suggest that reduction of Na<sup>+</sup>-K<sup>+</sup>-ATPase activity after PGF<sub>2α</sub> treatment may be due to the reduction of the number of enzyme molecules or to masking of the active site of the enzyme without any change in enzyme characteristics. In addition, a change in membrane bound enzyme activity may be an early step in PGF<sub>2α</sub> induced luleolysis.
증례 : 소화기 ; 복강 내 종양으로 오인된 농양을 형성한 위궤양 천공 1예연세대학교 의과대학 강남세브란스병원 1소화기내과, 2영상의학과
유정환 ( Jung Hwan Yu ),장성일 ( Sung Ill Jang ),박정수 ( Jung Soo Park ),정교태 ( Kyo Tae Jung ),김주희 ( Joo Hee Kim ),김자경 ( Ja Kyung Kim ),이관식 ( Kwan Sik Lee ) 대한내과학회 2011 대한내과학회지 Vol.81 No.1
저자들은 복강 내 종양 의심 환자에서 위궤양 천공에 의한 복강 내 농양을 진단하고 약물치료만으로 완치된 예를 경험하여 이를 문헌고찰과 함께 보고하는 바이다. Gastric ulcer perforation usually results in panperitonitis, which requires surgical treatment. A peritoneal abscess also can occur with gastric ulcer perforation, but it is not a common complication of peptic ulcer disease. Here, we report a peritoneal abscess that mimicked a tumor and was caused by a gastric ulcer and provide a literature review. A 57-year-old woman was admitted to our hospital for evaluation of an abdominal mass found in another hospital, with no signs of infection. She underwent a left lobectomy of the liver due to choledocholithiasis. Abdominal computed tomography (CT) revealed a heterogeneous mass attached to the antrum of the stomach. At endoscopy, we confirmed that the gastric ulcer at the antrum of the stomach caused the abscess. After 4 weeks of antibiotics and proton pump inhibitor treatment, she was cured. In a patient with abdominal pain and a peritoneal abscess of unknown cause, the possibility of peptic ulcer perforation should be considered. (Korean J Med 2011;81:89-92)