양측성 전정장애 환자들의 전정기능검사

이근호,김재일,정필섭,전범석,이광우 대한신경과학회 1996 대한신경과학회지 Vol.14 No.4

다랑 토혈 후 발생한 뇌경색으로 인하여 간질중첩증을 보인 간성 뇌중 1예

오형근,정두신,이경복,양광익,박형국 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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의료정책에 따른 종합병원의 로비공간 변화

한광호,함욱,박창근,이낙운 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.B

The purpose of this study are observing changing direction of lobby space that happen by change of medical environment investigating lobby space of General Hospital by our country's medical policy change time and supply pabulum that need in forward Hospital Architecture planning. Results of this study are as follows ; Since Whole National Insurance enforcement from 1993 to 1995, form of general hospital lobby is form that outpatient entrance and inpatient entrance are detached. And lobby function divided to waiting space for medication, requisition space and also that is appearing being detached with rest space for user. ntil 1999 since 1996 that is since Medical Treatment Information System construction, the biggest characteristic of General Hospital lobby form is making Hospital Street itself do improving efficiency of flow planning being included in lobby

Global-MAHN에서 라우팅 오버헤드 개선에 대한 연구

張良根,金玄旭,李光培,吳世德,裵振勝,金在浩 明知大學校 産業技術硏究所 2007 産業技術硏究所論文集 Vol.26 No.-

In this Paper, we studied the mechanism that increases the network reliability and decreases network load in GMAHN environment based on the AODV routing protocol. This proposed algorithm is the research on the algorithm, minimizing network overhead by preventing unnecessary network overhead previously and adapting Local repair mechanism to efficient data transmission when route error happens in network, in GMAHN environment. To evaluate the proposed algorithm's performance, we analyzed the proposed algorithm and adapting in various experiment environment according to 5 experiment viewpoint such as node movement, gateway network zone, mobile node number, flow number. After evaluating the experiment, we confirmed better network improvement altogether through following result such as total average data reception rate's increase, average data transmission time's decrease, network overhead's decrease than existing GMAHN algorithm.

광학활성 B-Alkoxy-9broabicyclo[3.3.1]nonane-Potassium Hydride 환원계에 의한 라세미 에폭시화물의 분할

李光雨,孔亨根,車震淳 嶺南大學校附設 基礎科學硏究所 1986 基礎科學硏究 Vol.6 No.-

In this study, chiral B-alkoxy-9-borabicyclo[3.3.1]nonane-potassium hydride systems were applied to the resolution of representative racemic epoxides, namely 1,2-epoxybutane, 1,2-epoxyoctane and styrene oxide. Chiral B-alkoxy-9-BBN systems were synthesized from the reaction of 9-BBN with (-)-isopinocampheol and (-)-cis-myrtanol, respectively. The resolution of 2 equiv of racemic epoxide was carried out with 1 equiv of the reducing system at 0℃. Thus, the 1 equiv of epoxide was reduced to the alcohol, remaining the other 1 equiv of epoxide intact. The resolving ability of these systems in terms of optical purity of the alcohol appeared to be 25-40% in the case of aliphatic epoxide and 9-12% in the case of styrene oxide. The absolute configuration of the alcohols is consistent with (R)-(-)-aliphatic alcohol and (S)-(-)-1-phenylethanol.

강원도 인제군 원대리 자연습지의 식물상

박완근,유석인,박광서 강원대학교 삼림과학연구소 2000 Journal of Forest Science Vol.16 No.-

강원도 인제군 남면 원대리 자연습지를 대상으로 1999년 4월부터 동년 10월까지 관속식물상을 조사한 결과 71과 175속 228종 1아종 33변종 3품종, 총 265종류가 분포하는 것으로 나타났으며, 이 가운데 갈대, 달뿌리풀, 삿갓사초, 골풀, 구릿대, 버드나무 등의 수생 및 관속식물은 19과 24속 31종 5변종 1품종, 총 37종류가 분포하고 있었다. 본 조사지역내 식생의 특성을 파악하기 위해 식물사회학적조사를 실시한 결과 갈대군락, 갯버들-횐물봉선아군락, 조팝나무-사철쑥아군락으로 분류되었다. This study was to estabilish the composition and vegetation of vascular plants on natural mashes in Wondae-ri(710m; 37˚ 58' 30" N, 128˚ 12' 15" E). This work was conducted from April to October, 1999. Vascular plants were composed of 71 families, 175 genera, 228 species, 1 subspecies, 33 varieties and 3 formae, totaling 265 taxa. Among the investigated vascular plants, 19 families, 24 genera, 31 species, 5 varieties 1 formae, totaling 37 taxa(13.9%) were hydrophytes and hygrophytes. The forest vegetation was classified Into 1 community and 2 subcommunities ; A.Phragmites japonica community A-1.Salix gracilistyla-Impatiens noli-tangere subcommunity A-2.Spiraea prunifolia var. simpliciflora-Artemisia capillaries subcommunity Key words : natural mashes, hydrophytes and hygrophytes

고령화와 임금피크제

지광수,조기전,이영근 朝鮮大學校 經營經濟硏究所 2007 經營經濟硏究 = Management and economics research Vol.30 No.2

Shaphylococcus enterotoxin B와 lipopolysaccharide를 작용시킨 사람 섬유아 세포에서 생성된 Transforming Growth Factor-β₁의 정량적 분석

이성근,김광혁,김욱규,김종렬,정인교,양동규 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

TGF-β1 is a potent chemotactic factor for inflammatory cells and fibroblasts. It also stimulates the celluar source and components of extracellular matrix and the production of proteinase inhibitors. Collectively, these biologic activities lead to the accumulation and stabilization of the nascent matrix, which is vital to infection control. The objective of this study is to investigate production of TGF-β in vitro fibroblast culture in the presence of Staphylococcus enterotoxin B(SEB) and/or lipopolysaccharide(LPS) and to elucidate the role of TGF-β1 which may be responsible for infection control. The fibroblasts were originated from gingiva and facial dermis in 26 year-old male patient. In the presence of LPS(0.01㎍, 0.1㎍, 1.0㎍), SEB(0.01㎍, 0.l㎍, 1.0㎍) respectively, cells(5×103ml) were cultivated in vitro. At 1, 3, and 5 days after incubation, cells were counted. Also, cells(2.5×105ml) were cultivated in EMEM with LPS(0.01, 0.1 and 1.0㎍), SEB(0.01, 0.1 and 1.0㎍) respectively and LPS(0.1㎍) and SEB (0.1㎍) in combination for 24,48, and 72 hours respectively. Culture supernatants were harvested at 1, 2, and 3 days after incubation period and triplicate culture supernatants were pooled and TGF-β1 was assayed in duplicate. The results were as follows. 1.In gingival fibroblast induced with SEB and LPS respectively or in combination, the suppression of cell Proliferation occurred very significantly since 3 days after incubation, compared with the control and the production of TGF-β1 occurred very significantly at 1 day after incubation, compared with the control. 2.In facial dermal fibroblast induced with SEB and LPS respectively or in combination. the suppression of cell proliferation occurred very significantly at 1 day after incubation, compared with the control. In SEB exposure, the production of TGF-β1 was decreased very significantly at 1 day after incubation, compared with the control. However, in LPS, SEB and LPS exposure, the production of TGF-β1 was increased very significantly at 1 day after incubation, compared with the control. In conclusion, the concentration of bacterial toxins and the incubation period correlated with cell proliferation and production of TGF-β1 very significantly. The gingival and facial dermal fibroblasts have different phenotype each other The orchestrated understanding of fibroblast proliferation and TGF-β1 production play an important part in host defense against the bacterial Infection and may prevent tissue necrosis such as necrotizing fasciitis and life-threatening syndrome such as multiple organ failure.

다량 토혈 후 발생한 뇌경색으로 인하여 간질증첩증을 보인 간성 뇌증 1예

오형근,정두신,이경복,양광익,박형국 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

Status epilepticus (SE) has been described as a rare manifestation of hepatic encephalopathy. Massive bleeding and subsequent anemia may precipitate atherothrombotic cerebral infarction. Stroke is one of the possible causes of SE. A 69-year-o1d male with decompensated alcoholic liver cirrhosis presented with altered mental state and generalized convulsive SE after massive hematemesis due to varix bleeding. The hemoglobin level was 5.5 mg/dL and blood ammonia level was more than twice the normal level. The seizure was resolved after prompt and aggressive treatment for SE. The blood ammonia level was normalized after treatment for hepatic encephalopathy, but the patient' s mental state was not recovered. Brain MRI revealed multiple ischemic lesions in the both cerebral hemisphere. We present the patient as SE after acute ischemic stroke associated with anemia in hepatic encephalopathy.

가열식품중의 Acrylamide : 검출농도, 생성기작, 그리고 독성을 중심으로 Detection Level, Formation Mechanism, and Toxicity of Acrylamide

이광근 한국산업식품공학회 2003 산업 식품공학 Vol.7 No.2

Since the Swedish National Administration (NFA) and researchers from Stockhorm University announced that acrylamide, a toxic potentially cancer-causing chemical, was formed in many types of food cooked at high temperature in April 2002, there have been a lot of international meetings and researches dealing with formation mechanism and toxicity of arylamide. It is hard to surely figure out the mechanism and toxicity of acrylamide at present time. This article deals with the detection levels in various foods, toxicity and formation mechanism o acrylamide. Acrylamide formation during food processing and cooking was confirmed by researchers of UK, Sweden, Switzerland and United States. They insisted that acrylamide in heated foods was formed by Maillard reaction between asparagine and glucose during cooking and food processing. It is well-know that heating time and temperature are significant factors for acrylamide formation in food processing. Regarding to the toxicity of acrylamide we need more experimental data to conclude its toxicity for humans. So far there is no credible evidence that acrylamide in foods poses a human cancer risk. Though acrylamide increased the incidnece of tumors in the high-dose rodent test, it is difficult to relate its toxicity to the human carcinogens. In the future, more accurate analysis of acrylamide in various foods, the human toxicity, and reduction study based on the formation mechanism should be investigated to prevent consumer's confusion.