나프틸기를 포함하는 퓨록산 유도체의 합성

黃匡鎭,南賢祐 홍익대학교 산업기술연구소 2002 産業技術 Vol.12 No.-

Furoxan derivatives containing naphthyl group was designed and synthesised as pohtochemical nitric oxide precussor. Naphthyl furoxan 4 was prepared by the [2+3] cycloaddition of the nitrile oxide generated in situ from the iminoyl chloride 3. The preparation of iminoyl chloride 3 was proceeded from naphthyl aldehyde 1 by the reaction with N-chlorosuccinimide following oxime formation. Naphthyl furoxan 4 was irradiated on 300 nm in CH2Cl2 to give alkyne 5 confirming NO generation.

광중합복합레진의 두께에 따른 투명도 차이가 수복물의 색상에 미치는 영향

황인남,이광원 大韓齒科保存學會 1999 Restorative Dentistry & Endodontics Vol.24 No.4

니트로크라이센 유도체의 합성에 관한 연구

黃匡鎭,김진국,남현우 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-

In an attempt to provide a useful light-emitting material in the organic electroluminescence diode, nitrochrysene 5 was prepared by the nitration of the tetrahydrochrysene 4 using dinitrogen tetraoxide as a key step. The chrysene 4 was obtained from the methyl cinnamate in 3 steps. The mono-nitration was confirmed by the IR, ^1H-NMR and ^13C-NMR spectra of chrysene 5. The results suggest that the synthetic methods for the nitrochrysene 5 is applicable to the synthesis of various chrysene derivatives containing donor-acceptor groups at 2, 8-positions.

動力耕耘機Engine의 性態曲善에 關한 硏究

黃光性,許南秀 진주산업대학교 1988 論文集 Vol.26 No.-

This study was initiated to evaluate the performance of 8ps Diesel engines detached from power tiller and to find the possibility of offering a rational guide in selecting and inspecting the engines. For this purpose. 8ps engines of 3 different engine builders were used in measuring the maximum power, normal power. torque and fuel consumption rate at different engine speeds. The result of the study are summarized as follows: 1. The average of the normal powers specified by the 3 engines was 8ps at 2,200rpm. However, in the test the average power of 3 engines at 2,2000rpm was 7.9ps, 7.6ps and 7.8ps which was almost same. And 8ps which was presented as a rated power was measured around 2,230rpm. 2. The average of the maximum powers specified by the 3 engines was 14ps/2,400rpm, 12ps/2,200rpm, and 11ps/2,200rpm. However, in the test the average power of 3 engines at 12.3ps, 11.3ps and 10.6ps which was lower than the average of specified powers at the same engine speed. 3. Fuel consumption rates normal power was 1,900rpm and maximum power was 1.800rpm. Fuel consumption rates of 3 engines was almost same. 4. Torque was increased about 0.1kg.m/100rpm untim 2,000rpm at normal power and 2,100rpm at maximum power, after that time it was decreased gradually.

수출용 축양품종 가지의 염절임 공정의 최적화

남학식,김남우,황성희,윤광섭,신승렬 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

가지의 수출 경쟁력 향상을 위한 한 방안으로 수출용 가지품종인 축양품종을 염가공품으로 개발하기 위하여 염절임공정을 최적화하였다. 염절임 시간, 절임온도, 염농도를 독립변수로 하고 절임 후 수분함량, 염도, 표면과 내부의 색도 등을 종속변수로 하여, 중심합성계획법으로 실험을 설계하여 최적조건을 얻고자 하였다. 수립된 이차회귀모형으로 예측식을 수립할 수 있었으며 특히 수분함량이나 염도, 표면과 내부의 L과 b 값에 대하여 높은 적합도를 보여 최적조건을 수립하기 위한 제한 변수로 선정하였다. 염농도를 중심점(30%)에서 고정시켜서 얻은 절임시간과 온도는 각각 5.5~6.5일과 13-17℃였으며, 이때의 종속변수의 제한 요건으로는 수분함량 84%이하, 염도 14%이하 표면 L값 10-20, b값 0이하, 내부 L 값은 70-75, b 값이 16-18이었다. This study was conducted to the optimize salting process of eggplant for development new product and enhancement quality for export. Three variables by five level central composite design and response surface methodology were used to determine optimum conditions for salting time, temperature and salt concentration. Optimization of the process was conducted using the combination of the moisture content, salinity and color of surface and inside of salted eggplant. The regression polynomial model was suitable (P>0.05) by Lack-of-Fit analysis with highly significant. To optimize the process, based on surface response and contour plots, the individual contour plots of the response variables were superimposed. The optimum conditions for this process were 6 days and 15℃ at 30% concentration under the optimum of restricted variables as moisture content was below 84%, salinity was below 14%, L and b value of surface were 10 to 20 and below 0, L value and b value of inside were 70 to 75 and 16 to 18.

식물플라크톤의 세포외배출유기물을 고려한 소양호의 1차생산과 유기물 부하

남궁현,김범철,황길순,최광순,김철구 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

The autochthonous and allochthonous organic carbon loading were measured in Lake Soyang, to estimate the amount of carbon loading into the lake and the contribution of their sources to the lake's carbon loading. Autochthonous carbon loading was estimated from phytoplankton primary production with the extracellular organic carbon(EOC). Allochthonous loding was determined by measuring dissolved organic carbon(DOC) and particulate organic carbon(POC) concentration in the main inflowing Soyang River. Both autochthonous and allochthonous organic carbon loading were high during the summer, from July to September, and accounted for 43.2% and 71.7% of the annual loading, respectively. Primary productivity was elevated up to 1,000 mgCm^(-2)d^(-1)during summer and lowest in winter. EOC production from phytoplankton was also large in summer, resulting in a high DOC concentration in the lake water. Primary production of phytoplankton and allochthonous organic matter loading from the watershed contributed to 53.6% and 46.4% of total loading, respectively. The EOC production accounted for 4.4~21.2% of POC primary production, implying that EOC production of phytolankton must be considered in estimation of primary production.

수술로 절제된 간의 국소 결절성 증식의 임상적 특징

황남철,최문석,이준혁,고광철,백승운,유병철,이종철,이광웅,조재원,박철근 대한간학회 2004 Clinical and Molecular Hepatology(대한간학회지) Vol.10 No.2

목적: 간의 국소 결정성 과형성은 일반적으로 특별한 치료가 필요 없는 양성 종양이다. 그러나 드물지만 합병증이 발생한 경우와 진단이 불확실한 경우에는 수술을 시행하게 된다. 이에 저자들은 간절제술을 시행한 국소 결절성 과형성의 임상적, 영상학적 특징들을 알아보고자 하였다. 대상과 방법: 1995년부터 2003년까지 수술을 시행하여 조직을 확인한 국소 결절성 과형성 환자 10명을 대상으로 연령, 성별, 실험실 검사 및 영상 소견과 조직 소견을 분석하였다. 결과: 연령의 중앙값은 37.5세, 남녀 비는 1.5:1이었다. 5예에서는 간세포선종이나 간세포암종을 감별할 수 없어서 수술을 시행하였으며, 수술 후 우연히 진단된 예는 4예이었다. 간세포암종의 위험 인자를 가지고 있었던 예는 4예(B형 간염 바이러스 보유자 3예, 간경변 2예)이었다. CT검사가 시행되었던 6예 중 5예는 동맥기에서 조영 증강을 보였고 문맥기 및 지연기로 감에 따라 주변과 동일(4예)한 또는 감소(2예)되는 양상을 보여 간세포암종과의 감별이 어려웠다. 크기는 3.2±2.2㎝이었으며 위치는 간우엽의 후하구역(S6)에 가장 많았다(30.0%). 4예에서 수술 전 침생검을 시행하였으나 고분화 간세포암종이나 간세포선종과의 감별이 어려웠다. 결론: 임상상, 영상검사 및 간침생검으로도 간세포암종이나 간세포선종과의 감별이 어려운 경우 수술을 시행하였으며 수술 전에는 발견하지 못하였지만 다른 질환으로 인한 수술시 우연히 발견된 경우도 있어 국소 결절성 과형성의 수술 전 진단이 어려운 경우가 적지 않음을 알 수 있었다. Background/Aims: Focal nodular hyperplasia (FNH) is a benign hepatic tumor with few serious complications and no malignant transformation. However, differential diagnosis between FNH and other liver tumors, especially hepatocellular carcinoma, is often difficult. Methods: Clinical features of surgically resected FNH were reviewed. From January, 1995 to February, 2003, 10 patients with surgically resected FNH were enrolled. Their age, sex, results of laboratory examination, imaging studies and pathologic findings were evaluated. Results: Median age was 37.5 years and sex ratio (male:female) was 1.5:1. In 5 cases, resection to exclude hepatic adenoma or HCC was performed. Four cases were diagnosed incidentally after surgery. Four patients had risk factors for HCC, such as hepatitis B virus infection, liver cirrhosis or both. The size of FNH was 3.2 2.2 cm. The most common site of the tumor was segment 6 (30.0%). Differential diagnosis with HCC was difficult in 5 of six cases in whom CT was performed. Although needle biopsies were performed preoperatively in 4 cases, it was difficult to distinguish FNH from hepatic adenoma or HCC. Conclusions: FNH was resected due to uncertainty of diagnosis, or incidentally during hepatectomy in patients with other liver disease. In the former, differential diagnosis with hepatic adenoma or HCC was a major problem despite extensive work-up including dynamic CT or biopsy. (Korean J Hepatol 2004;10:135-141)

金 合金中의 게르마늄 分析을 爲한 微分 펄스 폴라로그라피법

黃吉男,兪光植 울산대학교 1987 연구논문집 Vol.18 No.1

微量의 게르마늄을 gallic acid 와 착물을 형성시킨 다음에 10 M Ge 를 分析할 수 있는 폴라로그라피법을 개발하였다. 게르마늄의 微分펄스폴라로그람은 0.1M KCL용액에 0.02M 濃度의 gallic acid 를 가하고 pH를 1.0이 되도록 조절한 지지전해질에서 얻었다. Gallic acid의 濃度는 게르마늄의 約 10,000倍 以上일때에 Ge(Ⅳ)의 착물이 완성되고 만족한 환원전류를 얻을수 있었다. 게르마늄이 金과 共存할 때는 金의 환원파가 Ge(Ⅳ)의 것과 중첩되어 분리정량이 불가능하므로, 하이드라진을 가하여 Au(Ⅲ)만을 金屬으로 환원 제거 시키므로서 金합금주의 게르마늄分析이 可能하였다. As(Ⅴ), Sn(Ⅳ), Sb(Ⅴ), Fe(Ⅲ), Mo(Ⅲ), In(Ⅲ), 및 Cd(Ⅱ)등은 게르마늄분석에 영향을 미치지 않지만 Pb(Ⅱ)는 방해하였다. A polarographic determination method of trace amount of germanium has been developed by using gallic acid as complexing agent for 10-7M range of Ge. The polarogram of germanium was obtained in the supporting electrolyte of 0.1M kcl containing 0.02M gallic acid which was adjusted the pH to 1.0 Germanium-gallic acid complex seemed to be completed at the concentration of gallic acid over 10,000 times of germanium concentration and gave satisfactory reduction current of Ge(Ⅳ). The addition of hydrazine hydrate, however, made it possible to determine germanium in the presence of gold(Ⅲ). As(Ⅴ), Sn(Ⅳ), Sb(Ⅴ), Fe(Ⅲ), Mo(Ⅲ), In(Ⅲ), and Cd(Ⅱ) do not interfere for the germanium determination, but lead(Ⅱ) does.

구강 악성 흑색종에서 PCNA 발현에 관한 면역조직화학적 연구

황경균,남윤우,이재일,이종호,심광섭,김명진 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.6

Malignant melanoma arising from the mucosa of head and neck region was rare and showed poor prognosis. Some of malignant melanoma were transformed from benign melanotic lesion. Malignant melanoma had high cellular proliferation and rapid growth. The percentage of PCNA-positive cell (labeling index) is high in many malignant tumor. So we compared the pattern of PCNA expression in the melanotic lesion. We performed the immunohistochemical study in malignant melanoma(19 cases), benign melanotic macule(24 cases) and normal mucosa(20 cases) were diagnosed in Seoul National University Dental Hospital between 1980 and 2000. Positive PCNA staining was found mainly in malignant melanoma. The mean PCNA expression in malignant melanoma, melanotic macule, normal tissue were 29.2%, 1.4%, 0%, respectively. Significant differences in PCNA expression were noted between malignant melanoma and melanotic macule(p<0.01), normal mucosa(p<0.01). These result suggested that the PCNA expression seems to be used as a diagnostic indicator for malignancy in malignant melanoma and melanotic lesion.

可變構造에 의한 편로드 유압서어보실린더의 動的硏究

許南秀,黃光性 진주산업대학교 1988 論文集 Vol.26 No.-

This paper describes the application of the variable structure control concept for electrohydraulic servomotor system with single-rod cylinder. The result of variable structure system was compared to that of the fixed structure system when system parameter variations exit. 1. Dynamic Characteristics of fixed structure system were different from operating direction of poston, but those of VSS were same approximately. 2. VSS was realized rapid response without overshoot. 3. The large gradient of switching line was reached steady state rapidly within the range of reaching condition.