건진센터 수검자 자료를 이용한 비만지표에 대한 연구

김상만,최희정,이득주,김광민,윤수진 대한비만학회 1997 The Korean journal of obesity Vol.6 No.2

We have examined l5145 persons(7468 men 7677 women) to determine the role of Obesity Index(body mass index, WHR, body fat percent) on the risk of various chronic disease. All the subjects were pooled from Health Examination Center who took the annual health examination from June, 1994 through Jan, 1997, BMI(Body mass index, kg/㎡), WHR(Waist hip ratio) were measured and correlated with the frequency of chronic disease. In order to evaluated the BMI, WHR, Body Fat as an independent factors on rnorbidity, analysis of covariance was applied adjusted for age. The risk of variows chronic diseases were also analyzed with obesity, defined by BMI above 26kg/㎡ (men), 25kg/㎡ (women), by logistic regression adjusted age and sex. Risk of hypertension was 2.6 with 95% eonfidence interval of 1.9-2.8 in obese group. Risk of diabetes mel1itus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.2(2.3-4.4), 1.2(0.9-1.4), 2.1(1.7-2.8), 1.4(1.1-2.6) and 1.3(0.8-2.3) respectiveiy. The risk of various chronic diseases were also analyzed with obesity, WHR above 0.9(men), 0.81(women), by logistic regression adjusted age and sex. Risk of hypertension was 1.7 with 95% confidence interval of 1.4 -2.1 in obese group. Risk of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.1(2.3-4.0), 1.2(0.9-l.4), 1.4(1.1-2.6), 2.4(l.8-4.8) and 2.1(1.2-4.1) respectively. The BMI, WHR were independent risk factors for various chronic diseases.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

히터를 내장한 고온 산소센서의 개발

이광만,고성택 경북대학교 센서기술연구소 1993 연차보고서 Vol.1993 No.-

마이크로머시닝 기술과 반도체 공정기술을 활용하여 히터가 내장된 고온 산소센서를 개발하였다. 얇은 실리콘 다이아프램 위에 백금히터와 온도감지기를 내장시켜 작은 전력으로 구동되고 on-site 온도측정이 가능하였다. 약 2와트 부근의 전력에서 약 800℃의 온도를 얻었다. 고주파 반응성 스퍼터링법으로 형성된 이트리아가 약 8몰%가 함유된 지르코니아(YSZ)박막을 고체전해질로 사용하였다 제조된 산소센서는 산소함량이 0에서 18몰%의 범위 내에서 산소함량과 측정전류의 상관관계가 직선적인 응답 특성을 보였다. A high temperature oxygen sensor is developed using micromachining techniques and microelectronic fabrication technology. It is possible to have low power diriving and on-site temperature measurement due to the on-chip platinum heater and temperature detector on the thin silicon diaphragm. The sensor can be operated up to 800℃ and require about two watts power. The YSZ thin films as a solid electrolyte were deposited by reactive suputtering method with the target (8mol% of Y-2O_3 in the ZrO^2). The fabricated oxygen sensors have been shown a linear relationship between the oxygen content and the current from the measurement within 0 to 18 mol% of the oxygen contents.

유착성 견관절낭염 환자에서 견갑상신경과 견갑배신경의 병합 차단술의 효과

이삼규,노성만,선광진 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Objective : To investigate the effect of combined nerve block of suprascpular and dorsal scapular nerve as a means of pain management in adhesive capsulitis of shoulder. Method : Of the 55 patients with adhesive capsulitis of shoulder, 30 patients〔age: 62.55(47.2-72-7) years, symptom duration: 60(3-365) days, 12 males and 28 females〕were treated with combined nerve blocks of suprascpular and dorsal scapular nerve as a means of pain management, But, 25 patients〔age : 54.0(25.0-75.0) years, symptom duration: 90(3-730)days, 11 males and 14 females〕were not treated with nerve block. We measured the ROM of flexion and external rotation(˙) as degree via AMA method and VAS(mm). as a degree of shoulder pain weekly. We defined therapeutic duration as above 80% recovery of normal active ROM in flexion and external rotation and below 40mm in VAS. Results : 1) There were significantly decreased VAS from 90mm to 30mm in postnerve block group during serial follow-up exam(p<0.001). 2) There were significantly increased ROM of shoulder flexion from 150˚ to 170˚ in post-nerve block group duing serial follow-up exam (p<0001). 3) There were significantly increased ROM of shoulder external rotation form 40˚ to 60˚ in post-nerve block group during serial follow-up exam(p<0.001). 4) There was significantly increased in exercise compliance(sself-exercise time duration per day) from 60.0 minute to 92.0 minute and decreased in therapeutic duration from 6 weeks to 3 weeks(p<0.001). Conclusion : We concluded that the combined nerve blocks of suprascapular and dorsal scapular nerve were simple, safe, and effective procedure and beneficial to pain relief and shortening of the theraprtic duration of rehabilitative management in patients with adhesive capsulitis of shoulder.

센서응용을 이한 CMOS열전대의 공정기술 개발

이광만,김진섭,이춘흥,Liu, C.C. 경북대학교 센서기술연구소 1995 연차보고서 Vol.1995 No.-

마이크로 열전센서는 마이크로히터와 열전소자로 구성된다. 열전도율이 낮고 내부응력이 최소화된 NON절연막 다이아프램을 LPCVD법, APCVD법 및 실리콘 이방성식각법을 각각 활용하여 형성하였다. Si_3N_4 및 SiO_2의 두께가 각각 1500Å 및 3000Å의 조합인 NON막이 가장 양호한 응력특성을 나타내었다. 고주파 스퍼터링법으로 형성된 백금박막을 이용한 히터와 온도감지기로 형성된 마이크로 가스유량센서를 제조하고 그 동작특성을 측정하였다. 유량센서의 동작특성은 100∼500sccm의 유량범위에서 양호한 선형성을 보였다. CMOS공정기술과 호환성을 갖는 마이크로 유량센서의 마스크패턴과 공정을 각각 설계하였다. A micro thermosensor is composed of a microheater and a thermo element. NON insulator diaphragm with low thermal conductivity and minimum internal stress was fabricated^by using LPCVD, APCVD and silicon anisotropic etch techniques. The deposited NON film represented the best stress characteristics when the thickness of Si_3N_4 and SiO_2 are 1500Å and 3000Å, respectively. A micro gas-flow sensor was fabricated and characterized that is consist of platinum thin film heater and temperature detector. The performance characteristics of the micro gas-flow sensor shows a good linearity within 100-500sccm flow rate range. Mask pattern and CMOS process of micro gas-flow sensor have been designed according to CMOS process technology.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

실리콘 미세가공 기술을 이용한 마이크로 진공 센서

이광만,고성택,김영민,고희선 濟州大學校 工科大學 産業技術硏究所 1998 尖端技術硏究所論文集 Vol.9 No.1

A micro-vacuum sensor has been fabricated by using silicon micromachining techniques and platinum thin film. NON insulator was deposited by LPCVD and APCVD methods. The insulator diaphragm was fabricated by silicon anisotropic etching in TMAH solution. Thin film platinum heater and temperature detector were deposited by rf sputtering method and patterning was performed by means of lift-off method. Deposited platinum heater and temperature detector have been shown a linear Ⅰ-Ⅴ characteristics. TCR(temperature coefficient of resistance) of thin film platinum heater and temperature detector was about 0.0042/℃. Fabricated vacuum sensor was measured in the range of 1x10­³Torr to 1×10² Torr, and shows a good linear operating characteristics in the range of 1x10­² Torr에서 1x10˚Torr.

실리콘 미세가공 기술을 이용한 마이크로 진공 센서

이광만,고성택,김영민,고희선 濟州大學校 産業技術硏究所 1998 산업기술연구소논문집 Vol.9 No.1

A micro-vacuum sensor has been fabricated by using silicon micromachining techniques and platinum thin film. NON insulator was deposited by LPCVD and APCVD methods. The insulator diaphragm was fabricated by silicon anisotropic etching in TMAH solution. Thin film platinum heater and temperature detector were deposited by rf sputtering method and patterning was performed by means of lift-off method. Deposited platinum heater and temperature detector have been shown a linear I-V characteristics. TCR( temperature coefficient of resistance) of thin film platinum heater and temperature detector was about 0.0042/℃. Fabricated vacuum sensor was measured in the range of 1X 10^(-3) Torr to 1X10^(2) Torr. and shows a good linear operating characteristics in the range of 1x1^(-2) Torr에서 1X10^(0) Torr.

히터를 내장한 고온 산소센서의 개발(Ⅱ)

이광만,고성택 경북대학교 센서기술연구소 1994 연차보고서 Vol.1994 No.-

반도체 공정기술과 마이크로머시닝 기술을 활용하여 히터가 내장된 고온 산소센서를 개발하였다. 얇은 절연막다이아프램 위에 백금히터와 온도감지기를 내장시켜 0.6와트의 작은 전력으로 약 800℃ 의 온도를 얻었다. 고주파 반응성 스퍼터링법으로 형성된 이트리아로 안정화된 지르코니아(YSZ)박막을 고체전해질로 사용하였다. 제조된 산소센서는 산소함량이 0에서 18몰%의 범위 내에서 전류구동법으로 동작하여 음극영역의 감도는 -3.65㎂/pO_2의 양호한 선형성을 보였으며 2초 이내의 빠른 응답을 보였다. A high temperature oxygen sensor has been developed using micromachining techniques and microelectronic fabrication technology. It is possible to have temperature 800℃ using on-chip platinum heater and temperature detector on the thin insulating diaphragm with applying 0.6 watts. The YSZ thin films as solid electrolyte were deposited by reactive RF suputtering method. The fabricated oxygen sensors have been shown a semi-logarithmic relationship between the oxygen content and current from the measurement within 0 to 18 mol% of the oxygen contents. The sensitivity and response time of the oxygen sensor were -3.65㎂/pO_2 and less than 2 seconds, respectively.

자동차 실내 환경제어용 센서시스템 개발

이광만,도양희 경북대학교 센서기술연구소 1997 연차보고서 Vol.1997 No.-

자동차 실내 환경제어용 센서시스템을 개발하기 위하여 마이크로 가스유량 센서와 습도센서를 설계하고 제조공정을 수행하였다. 1차년도의 연구결과를, 바탕으로 가스유량 센서의 경우, 히터와 반도체열전대를 NON 절연막 브리지에 형성한 구조를 하고있다. 습도센서의 경우, 단일 히터만이 NON 절연막 브리지 위에 형성된 간단한 구조를 하고 있다. 이들 마이크로 센서들을 CMOS공정과 실리콘 미세가공기술을 이용하여 제조하였다. 마이크로 센서시스템을 위한 기초연구로 가스유량센서와 습도센서를 동일 칩상에 조합하고 구동회로를 함께 집적한 스마트센서를 설계하였다. 설계된 구동회로와 마이크로 센서를 검증하였다. A micro gas-flow sensor and humidity sensor have been designed and fabricated for the development of the sensor system which can be applicable to the automotive interior environmental control. For the case of gas-flow sensor, a heater and semiconductor thermocouples were formed on the NON bridge based on the results of first research year's. For the case of humidity sensor, it have a simple structure compose of single heater formed on the NON bridge. These micro sensors were fabricated by CMOS process and silicon micromachining techniques. A smart sensor composed of gas-flow sensor, humidity sensor and driving circuits was designed for the basic research. The designed driving circuits and micro sensors were verified.