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      • KCI등재

        댄스스포츠 참가에 따른 부부갈등해소와 결혼만족과의 관계

        이경일(Kyung Il Lee),정명수(Myung Soo Jung),김경란(Kyung Ran Kim) 한국사회체육학회 2001 한국사회체육학회지 Vol.16 No.-

        The purpose of this study is to investigate the relationship between house wife`s participation on dance sports, marital conflict resolution, and marriage satisfaction. Specifically, it aims to examine: The influence of the dance sports involvement on marital conflict resolution, and marriage satisfaction. The subjects of this study was selected by cluster random sampling of involvement(participation 561, non-participation 177) in dance program facility of Seoul, Kyung-ki, Daejun, and Kwang-ju. The questionnaire for the marital conflict resolution had been developed by Hyun(1994). And also the marriage satisfaction had been developed by Kwon & Chei(1998) The statistical methods such as factor analysis and multiple regression analysis. Marital conflict resolution of dance sport participant house wife are partially influence marriage satisfaction. Among marital conflict resolution of sub-factor, higher dissatisfaction, attack behavior, sex trouble, common time conflict is higher of control and evasion lower of adjustment.

      • 유아의 다중지능 향상을 위한 요리 활동프로그램의 효과 검증

        김혜란 ( Hye Ran Kim ),이경화 ( Kyung Hwa Lee ),서호찬 ( Ho Chan Seo ) 국제뇌교육종합대학원대학교 뇌교육연구소 2014 뇌교육연구 Vol.14 No.-

        본 연구는 유아기의 다중지능 발달의 중요성을 인식하고 유아를 위한 효율적인 교육프로그램을 제공할 수 있는 기초자료를 확보하고자 요리활동 프로그램을 제작하고 적용해봄으로써 요리활동이 유아의 다중지능 향상에 미치는 영향을 알아보는데 교육적 의의를 가진다. 연구의 대상자는 서울시에 소 재한 S유치원의 만 5세 유아 30명을 무선 선정한 후 실험집단과 통제집단에 15명씩 무선 배치하였다. 연구도구는 만 3, 4, 5세를 대상으로 개발하여 표준화시킨 유아 다중지능 검사 도구를 사용하였으며, 수집된 자료는 사전·사후 검사로 t-test를 실시하여 집단 간의 차이를 확인하였다. 8주간의 요리활동으로 실험집단과 통제집단을 비교하여 볼 때 실험집단에서 유아들의 다중지능 향상에 도움을 주었으며 구체적으로 언어 지능, 논리·수학 지능, 시각·공간 지능, 신체운동감각 지능, 음악 지능, 개인이해 지능, 자연탐구 지능에 각각 유 의미한 결과를 나타내었다. 이상과 같은 결과로 요리활동은 유아의 오감을 모두 사용하는 최적의 활동으로 지식이나 기술 습득뿐 아니라 공감과 만족감을 맛볼 수 있다는 점에서 가치 있는 활동으로 제시될 수 있으며 유아 개개인이 지니고 있는 각자의 다 양한 지적 특성에 적합한 교육적 경험의 기회로 요리활동이 활용되어지기를 기대한다. This study has its educational significance in the sense that I have tried to identify the importance of multiple intelligence development during ch ildhood and find out whether or not children``s multiple intelligence can be improved by such programs as cooking activities that have been produced and applied for the purpose of securing basic materials that can provide young children with efficient programs. To attain at its gold of study, I have established the following assumptions and verified its effects. The targets of research were randomly selected from 5-aged 30 children of S kindergarten located in Seoul and 30 of them were arranged into a test group and a control group. The measurement in this research were taken using inspection tools for children``s multiple intelligence developed and standardized for ages of 3, 4, and 5 by Kyung-Hwa Lee. The collected materials have been processed using t-test to find out effect of pre and post-examination through t-test in order to verify significance between those two groups. These are summaries of the result carried out on this study. At first, cooking activities have had impact on children``s linguistic intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s linguistic intelligence. Second, cooking activities have had impact on children``s logics`` math intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s logics`` math intelligence. Third. cooking activities have had impact on children``s visual`` spacial intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s visual`` spacial intelligence. Fourth, cooking activities have had impact on children``s music intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s music intelligence. Fifth, cooking activities have had impact on children``s inter-personal intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s inter-personal intelligence. Sixth, cooking activities have had impact on children``s personal understanding intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s personal understanding intelligence. As a result of taking universal consideration of such results of the study, cooking activities is regarded as a worthy activity not only for acquiring knowledge or technology as an optimal activity that uses all of children``s five senses, but also for experiencing successive feeling and satisfaction. Accordingly, I hope that these cooking activities might be utilized as a educational opportunity from which children enjoy various intellectual characteristics of their own.

      • KCI등재

        댄스스포츠 참여가 의사소통 , 갈등해소 및 결혼만족에 미치는 영향

        정명수(Myung Soo Jung),이경일(Kyung Il Lee),김경란(Kyung Ran Kim) 한국사회체육학회 2001 한국사회체육학회지 Vol.16 No.-

        The purpose of this study is to investigate the relationship between house wife`s participation on dance sports, marital communication, marital conflict resolution, and marriage satisfaction. Specifically, it aims to examine: The difference of marital communication, marital conflict resolution, and marriage satisfaction by characteristics of dance sports participation-non participation. The subjects of this study was selected by cluster random sampling of involvement(participation 561, non-participation 177) in dance program facility of Seoul, Kyung-ki, Daejun, and Kwang-ju. The survey questionnaires were used to collect the data The questionnaire for the formalization factor marital communication, had been developed by Lee(1991). The questionnaire for the marital conflict resolution had been developed by Hyun(1994). And also the marriage satisfaction had been developed by Kwon & Chei(199h). The statistical methods such as factor analysis, ANCOVA, multiple classification analysis. Path analysis were used to analyze the collected data From the analyses of the data, the study reached the following conclusions: Marital communication, marital conflict Resolution, and marriage satisfaction are partially different by dance sport participation-non participation. That is, dance sports participant is higher reason attitude, conciliatory attitude among sub-factor of marital communication, dance sports participant is higher compromise among sub-factor of marital conflict resolution, but marriage satisfaction is not different.

      • KCI등재

        조선후기 同姓마을의 형성과 洞約의 성격 변화 : 慶尙道 丹城縣 法勿也面 洞案의 분석

        김경란(Kim, Kyung Ran) 한국외국어대학교 역사문화연구소 2020 역사문화연구 Vol.74 No.-

        조선후기에는 同姓마을이 급격하게 확산되었고, 이에 따라 향촌사회의 지배구조 및 지배조직에도 변화가 초래되었다. 그 대표적인 예가 洞約(洞契)의 변화였다. 동성마을이 확산됨에 따라 상당수의 동약이 族契化하면서 그 운영에 상당한 변화가 있었고, 이에 대한 구체적 분석이 이 글의 목적이다. 조선후기 慶尙道 丹城縣 法勿也面에서는 몇몇 有力 姓貫들을 중심으로 동약이 시행되었다. 그런데 商山 金氏에 의해 동성마을이 형성됨에 따라 법물야면의 동약은 인적인 구성과 지역적 범위에 변화가 초래되었다. 그 내용을 요약하면 다음과 같다. 18세기 초반 무렵 법물야면의 동약을 주도했던 상산 김, 무송 윤, 진주 유씨 등은 단성현의 유력 성관들이었고, 이들 사족가문에 의해 법물야면의 동약이 시행되었다. 법물야면의 동안은 양반층이 중심이 된 上洞案의 성격을 갖고 있었지만, 1730년대 이후부터는 일부 中庶層의 참여도 이루어지기 시작하였다. 상산 김씨의 庶子들을 비롯하여 이천 서씨 등 계층적으로 중서층에 해당하는 새로운 성관이 동안에 기재되기 시작했던 것이다. 동안 기재인물의 거주지 역시 18세기를 경과하면서 평지촌, 내당촌으로 집중되는 양상이 나타났다. 평지촌, 내당촌은 상산 김씨의 동성마을이 형성되었던 촌락이었고, 법물야면의 동약을 주도했던 성관 중에서 동성마을을 형성했던 성관은 상산 김씨가 유일하였다. 상산 김씨의 동성마을이 확대되어 감에 따라 법물야면의 동약은 상산 김씨의 족계적 성격으로 변모했던 것으로 보인다. 한편, 조선후기 법물야면의 동약 시행과 관련된 자료로 18세기 중반에 작성된 『洞內穀物息利有司姓名冊』과 19세기 전반에 작성된 『許廳案』이 현전하고 있다. 『有司姓名冊』과 『허청안』에 기재된 인물들은 법물야면의 동약을 운영하는 실무적인 역할을 했던 존재로 파악할 수 있다. 이들은 신흥 세력들로서 계층적으로는 中庶層에 속하였다. 이 중에서 특히 주목되는 성관은 경주 최씨였다. 경주 최씨는 상법촌에 집거하며 동약 운영에 참여하는 등 사회적 성장을 이루었던 신흥세력으로 볼 수 있다. 그럼에도 불구하고 19세기에 들어 상동안과 별도로 허청안이 작성되고, 여기에 법물야면의 신흥세력이었던 경주 최씨가 대거 기록된 점은 시사하는 바가 크다. 즉, 19세기 법물야면의 동약은 18세기와는 달리 신흥 세력들을 『허청안』으로 분리하여 그 명부를 작성하였다. 이는 19세기 이후 신분제적 위기를 느낀 양반사족들이 상하합계에서 상계, 하계를 분리하려는 경향이 법물야면에도 동일하게 나타났던 것으로 볼 수 있다. 18세기 이후 평지촌, 내당촌을 중심으로 동성마을을 확대시켜 갔던 상산 김씨는 법물야면의 동약을 족계화하였고, 새롭게 성장한 신흥 세력과 일반 촌락민을 허청안과 하동안으로 분리하면서 신분제적 질서를 정비하는 동시에 이들에 대한 지배적 영향력을 유지해 나가고자 했던 것으로 여겨진다. During the late Joseon Dynasty, Dongyak (Village Covenants) was implemented centered on a few influential families in Beommurya-myeon, Danseong-hyeon, Gyeongsang-do Province. However, with the formation of consanguineous villages by the Sangsan Kim family, the Dongyak in Beommurya-myeon faced many changes in terms of the population composition and regional scope. The Sangsan Kim family, Musong Yun family, and the Jinju Yu family, who led the Dongyak in Beommurya-myeon during the early 18th century, were major influential families in Danseong-hyeon. Although the Dongan (list of names) from Beommurya-myeon was mainly a list of superior names focused on the noble class, it started to include some names from the middle class from the 1730s. The residential areas of those who were listed in the Dongan also became focused in the Pyeongji-chon and Naedang-chon areas during the course of the 18th century. Pyeongji-chon and Naedang-chon were areas where the consanguineous villages of the Sangsan Kim family were formed. Among those who have led the Dongyak in Beommurya-myeon, the Sangsan Kim family was the only family who formed consanguineous villages. With the expansion of the consanguineous villages of the Sangsan Kim family, the Dongyak in Beommurya-myeon seems have changed to represent the family tree of the Sangsan Kim family. The Sangsan Kim family, who had expanded the consanguineous villages centered on the Pyeongji-chon and Naedang-chon areas from the 18th century, transformed the Dongyak in Beommurya-myeon into its family tree. The family also classified newly rising powers and general residents into Heocheongan and Hadongan to organize the status-based order, and intended to maintain their controlling power.

      • KCI등재

        Chitin deacetylase from Absidia coerulea CHK-1 : Mycerial chitin deacetylase of a chitin deacelylase-hyperproducuing fungus, Absidia coerulea CHK-1

        Park, Chun,Kim, Jung Ran,Shin, Jae Kyoung,Kim, June Ki,Lee, Tae Kyun,Chung, Ji Chun,Park, Weon Hwan,Park, Sun Dong,Nam, Kyung Soo,Lee, Young Choon,Kim, Cheorl Ho 한국키틴키토산학회 1997 한국키틴키토산학회지 Vol.2 No.2

        A mycelial chitin deacetylase has been purified from a chitin deacetylase-hyperproducing fungus, Absidiα coerulea CHK-1. The purified enzyme had a molecular mass of about 62 kDa on denaturated and natural conditions. The pI was 5.5. The chitin deacetylase, when resolved by SDS-PAGE, was positive for Schiff staining, suggesting that the enzyme is a glycoprotein. When O-hydroxylated chitin (glycolchitin) was used as a substrate, the enzyme displayed a temperature optimum of around 50℃ and a pH optimum of around PH 5,5. The enzyme was stable to incubation from pH 3.0 to pH 6.5 at 4℃ for 24 hr. The presence of chitin protected the enzyme from heat inactivation, the extent depending upon the substrate concentration. The activity of the enzyme was stimulated by Mn2+ ion. The enzyme is active on chitooligosaccharides with more than two N-acetylglucosamine residues (M-acetylchitobiose). However, the enzyme is not active on N-acetylglucosamine. The enzyme had an apparent Km of 12.4 mM and Kcat of 32.4 /sec for glycol chitin, respectively.

      • SCOPUSKCI등재

        Prognostic analysis of uterine cervical cancer treated with postoperative radiotherapy: importance of positive or close parametrial resection margin

        Yi-Jun Kim,MD,Kyung-Ja Lee,MD,PhD,Kyung Ran Park,MD,PhD,Jiyoung Kim,MD,Yi-Jun Kim,MD,Kyung-Ja Lee,MD,PhD,Kyung Ran Park,MD,PhD,Jiyoung Kim,MD,Woong Ju,MD,PhD,Yun Hwan Kim,MD,PhD,Jihae Lee,MD 대한방사선종양학회 2015 Radiation Oncology Journal Vol.33 No.2

        Purpose: To analyze prognostic factors for locoregional recurrence (LRR), distant metastasis (DM), and overall survival (OS) in cervical cancer patients who underwent radical hysterectomy followed by postoperative radiotherapy (PORT) in a single institute. Materials and Methods: Clinicopathologic data of 135 patients with clinical stage IA2 to IIA2 cervical cancer treated with PORT from 2001 to 2012 were reviewed, retrospectively. Postoperative parametrial resection margin (PRM) and vaginal resection margin (VRM) were investigated separately. The median treatment dosage of external beam radiotherapy (EBRT) to the whole pelvis was 50.4 Gy in 1.8 Gy/fraction. High-dose-rate vaginal brachytherapy after EBRT was given to patients with positive or close VRMs. Concurrent platinum-based chemoradiotherapy (CCRT) was administered to 73 patients with positive resection margin, lymph node (LN) metastasis, or direct extension of parametrium. Kaplan-Meier method and log-rank test were used for analyzing LRR, DM, and OS; Cox regression was applied to analyze prognostic factors. Results: The 5-year disease-free survival was 79% and 5-year OS was 91%. In univariate analysis, positive or close PRM, LN metastasis, direct extension of parametrium, lymphovascular invasion, histology of adenocarcinoma, and chemotherapy were related with more DM and poor OS. In multivariate analysis, PRM and LN metastasis remained independent prognostic factors for OS. Conclusion: PORT after radical hysterectomy in uterine cervical cancer showed excellent OS in this study. Positive or close PRM after radical hysterectomy in uterine cervical cancer correlates with poor prognosi

      • SCOPUSKCI등재

        Synthesis of Methyl-substituted Bicyclic Carbanucleoside Analogs as Potential Antiherpetic Agents

        Kim, Kyung-Ran,Park, Ah-Young,Lee, Hyung-Rock,Kang, Jin-Ah,Kim, Won-Hee,Chun, Pu-Soon,Bae, Jang-Ho,Jeong, Lak-Shin,Moon, Hyung-Ryong Korean Chemical Society 2008 Bulletin of the Korean Chemical Society Vol.29 No.10

        Novel bicyclo[3.1.0]hexanyl purine nucleoside analogues were synthesized as potential antiherpetic agents via a bicyclo[3.1.0]hexanol (${\pm}$)-8, which was prepared using a highly efficient carbenoid cycloaddition reaction. A highly diastereoselective reduction of ketone and a Mitsunobu reaction for the condensation of glycosyl donor (${\pm}$)-12 with 6-chloropurine were employed.

      • SCIESCOPUS
      • SCISCIESCOPUS

        Enhanced activation of NAD(P)H: quinone oxidoreductase 1 attenuates spontaneous hypertension by improvement of endothelial nitric oxide synthase coupling via tumor suppressor kinase liver kinase B1/adenosine 5&vprime;-monophosphate-activated protein kina

        Kim, Yong-Hoon,Hwang, Jung Hwan,Kim, Kyung-Shim,Noh, Jung-Ran,Gang, Gil-Tae,Oh, Won Keun,Jeong, Kyeong-Hoon,Kwak, Tae Hwan,Choi, Hueng-Sik,Lee, In-Kyu,Lee, Chul-Ho Wolters Kluwer Health | Lippincott Williams Wilkin 2014 Journal of Hypertension Vol.32 No.2

        AIMS:: Guanosine 5&vprime;-triphosphate cyclohydrolase-1 (GTPCH-1) is a rate-limiting enzyme in de-novo synthesis of tetrahydrobiopterin (BH4), an essential cofactor for endothelial nitric oxide synthase (eNOS) coupling. Adenosine 5&vprime;-monophosphate-activated protein kinase (AMPK) is crucial for GTPCH-1 preservation, and tumor suppressor kinase liver kinase B1 (LKB1), an upstream kinase of AMPK, is activated by NAD-dependent class III histone deacetylase sirtuin 1 (SIRT1)-mediated deacetylation. &bgr;-Lapachone has been shown to increase cellular NAD/NADH ratio via NAD(P)H:quinone oxidoreductase 1 (NQO1) activation. In this study, we have evaluated whether &bgr;-lapachone-induced NQO1 activation modulates blood pressure (BP) through preservation of GTPCH-1 in a hypertensive animal model. METHODS AND RESULTS:: Spontaneously hypertensive rats (SHRs), primary aortic endothelial cells, and endothelial cell line were used to investigate the hypotensive effect of &bgr;-lapachone and its action mechanism. &bgr;-Lapachone treatment dramatically lowered BP and vascular tension in SHRs and induced eNOS activation in endothelial cells. Consistent with these effects, &bgr;-lapachone treatment also elevated levels of both aortic cGMP and plasma nitric oxide in SHRs. Meanwhile, &bgr;-lapachone-treated SHRs showed significantly increased levels of aortic NAD, LKB1 deacetylation, and AMPK Thr phosphorylation followed by increased GTPCH-1 and tetrahydrobiopterin/dihydrobiopterin ratio. In-vitro study revealed that AMPK inhibition by overexpression of dominant-negative AMPK nearly abolished GTPCH-1 protein conservation. Enhanced LKB1 deacetylation and AMPK activation were also elicited by &bgr;-lapachone in endothelial cells. However, inhibition of LKB1 deacetylation by blocking of NQO1 or SIRT1 blunted AMPK activation by &bgr;-lapachone. CONCLUSION:: This is the first study demonstrating that eNOS coupling can be regulated by NQO1 activation via LKB1/AMPK/GTPCH-1 modulation, which is possibly correlated with relieving hypertension. These findings provide strong evidence to suggest that NQO1 might be a new therapeutic target for hypertension.

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