저해음의 비음화 : 음운론 및 음성학적 접근 Its Phonology and Phonetics

안현기,권순석,김기열 대한언어학회 2000 언어학 Vol.8 No.1

Ahn, Hyunkee, Soon-Suk Kwon, and Ki-Yeol Kim. 2000. Obstruent Nasalization: Its Phonology and Phonetics. Linguistics 8-1, 27-38. This paper discusses a Korean phonological rule, Obstruent Nasalization--i.e., an obstruent is phonologically nasalized when followed by a nasal. As is well known, this rule is productively prevalent in Korean, but not in English. Within the Optimality Theoretic framework, the difference in this phonological pattern between the two languages is well captured by means of adjusting the dominance relationship between two constraints (markedness and faithfulness constraints). This constraint-based explanation, however, doesn't suffice our question of why the phenomenon is phonetically natural in Korean, but cross-linguistically rare. To this question, we will provide one possible answer by suggesting that the markedness constraint is phonetically oriented due to a phonetic constraint on laryngeal feature juxtapositions. (Kyung Hee University)

中風病辨證診斷標準에 의한 臨床的 硏究

任長信,文祥官,高昌男,權正男,曺基湖,金永錫,裵亨燮,李京燮 경희대학교 1997 慶熙醫學 Vol.13 No.3

삼풍백화점 붕괴사고시 혈액형의 결과와 유가족 진술과의 비교고찰

권기석,김영주 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

한국인 관상동맥의 변화양상에 대한 형태학적 연구

권태정,이상용,이한영,고영창,권기석,조재홍,김태공,김유훈,조갑래,서중석,이원태 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

방사선 조사선량에 따른 백서 악하선의 caspase-3 발현양상

권기정,최용석,황의환,이상래,고광준 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.37 No.1

Purpose : To investigate the caspase-3 expression in the acinar and ductal cells of rat submandibular glands after the irradiation of various doses. Materials and Methods: The male Sprague-Dawley rats weighing approximately 250 gm were used for this study. The experimental group was irradiated with a single absorbed dose of 2, 5, 10, and 15 Gy on the head and neck region. The rats were sacrificed on the 1st, 3rd, 7th, 14th, 21st, and 28th day after irradiation. The specimens including the submandibular gland were sectioned and observed using histopathological and immunohistochemical methods. Results : The local destruction of the acinar and ductal cells and the karyopyknotic nuclei of the acinar cells were observed in the 2 Gy and 5 Gy irradiation groups later than in the 10 Gy and 15 Gy irradiation groups. And the expression of caspase-3 was prominent only in the ductal cells in the 2 Gy and 5 Gy irradiation groups. Conclusion : This experiment suggests that radiation-induced apoptosis in the ductal cells of rat submandibular glands was induced by a low dose radiation associated with the activation of caspase-3 and radiation-induced necrosis was induced by a high dose radiation. (Korean J Oral Maxillofac Radiol 2006; 36 : 7-15)

Phenyl-N-benzoylchlorothioformimidate 誘導體의 加水分解 反應 메카니즘

權奇星,金千石,李龍九,成洛道 충남대학교 기초과학연구소 1992 연구논문집 Vol.12 No.-

25℃의 30%(v/v) dioxane-물의 혼합용매 속에서 pH 변화에 따른 X와 Y-치환된 phenyl-N-benzoylchlorothioformimidates(S)들의 가수분해 반응 속도상수를 측정하여 반응속도식을 유도하고, 경계 궤도 함수 상호작용, 용매효과, 일반 염기 촉매효과, 열 역학적 활성화 파라미터, 및 가수분해반응 생성물 분석 등의 결과로부터 pH 10.0 이하의 낮은 pH에서는 azocarbocation 중간체를 지나는 S_N1형 반응, pH 11.0 이상의 높은 pH에서는 사면체 중간체를 지나는 친핵성 첨가-제거(Ad_N-E)반응 그리고 pH 10.0과 11.0 사이에서는 이들 두가지 유형의 궤도 조절 반응이 서로 경쟁적으로 일어남을 제안하였다. The rate constants of hydrolysis of phenyl-N-benzoylchlorothioformimidates were determined by UV. spectrophotometry in 30% (v/v) aqueous dioxane at 25℃. On the basis of rate equation, general base catalysis, solvent effect, substituent effect, thermodynamic parameters, frontier orbital interaction and hydrolysis product analysis, it may be concluded that the hydrolysis of phenyl-N-benzoylchlorothioformimidates proceed through S_N1 mechanism via azocarbocation intermidiate below pH 10.0, while above pH 10.00 the hydrolysis proceeds through nucleophilic addition-elimination (Ad_N-E) mechanism. In the range of pH from 10.0 to 11.0 these two reaction occur competitavely.

급성 ST 분절 상승 심근경색증의 표준진료지침 설계

권선옥,김우식,오명기,나종천,이홍기,조욱현,최석구 인제대학교 2006 仁濟醫學 Vol.27 No.-

The use of critical pathways for a variety of clinical conditions has grown rapidly in recent years, particularly pathways for patients with acute myocardial infarction. We intend to determine the impact of a clinical pathway on ST-elevation myocardial infarction (STEMI) and to evaluate the efficacy and safety of facilitated percutaneous coronary intervention (PCI) compared with primary PCI. Low risk STEMI patients (ST elevation >0.1mV in more than 2 limb leads or ST elevation >0.2mV in contiguous precordial lead, chest pain lasting more than 30 min without response to nitroglycerin) will be included. All patients will be also treated medically according to critical pathway. STEMI is one of the common diseases in emergency medicine and so it is necessary to establish realistic treatment guidelines. The use of critical pathways will improve the quality of care.

N-(benzoyl)-C-(N-methylanilino)imidoylchloride 유도체의 가수분해 반응메카니즘

權奇星,李龍九,成洛道,金千石 충남대학교 기초과학연구소 1993 연구논문집 Vol.13 No.-

25℃의 50%(v/v) 메탄올-물의 혼합용매 속에서 pH 변화에 따른 X-치환된 N-(benzoyl)-C-(N-methylanilino)imidoylchloride(s)들의 가수분해 반응속도상수를 측정하여 반응속도식, 치환기효과, 용매효과, 염효과, 열역학적 활성화 파라미터 및 가수분해반응 생성물 분석 등의 결과로부터 pH3.0∼10.0까지의 사이에서는 azocarbonium ion 중간체를 지나는 S_N1형 반응, pH3.0 이하와 pH10.0 이상의 pH에서는 사면체 중간체를 지나는 친핵성 첨가-제거반응(Ad_N-E)이 일어남을 제안하였다. Rate constants of hydrolysis of N-(benzoyl)-C-(N-methyl-anilino)imidylchlorides were determined by UV spectrophotometry in 50% (v/v) aqueous methanol at 25℃. On the basis of rate equation, substituent effect, solvent effect, salt effect, thermodynamic parameters and hydrolysis product analysis, it may be concluded that the hydrolysis of N-(benzoyl)-C-(N-methyl-anilino)imidylchlorides proceed through S_N1 mechanism via azocarbonium ion intermediate in the range of from pH 3.0 to pH 10.0, while above pH 10.0 and below pH 3.0 the hydrolysis proceeds through nucleophilic addition-elimin ation (Ad_N-E) mechanism.

금호강 저질(sediment)중에 함유된 중금속의 분포와 오염원과의 상관성 검토

윤능기,이충원,서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

The sieved sampling of the sediments of the Kumho river was carried out along 5 minor tribrtaries to study the distribution of the heavy metals according to particle size and to locate the source of heavy metals contributing to the pollution of the Kumho river which flows through the Taegu city April in 1988. The results were as follows; The heavy metal concentrations generally increased with the decreasing size of sediments and were higher in lower portion of sediment than in upper one at the same particle size. The coefficients of variation of each heavy metal in the same particle size were similar generally, but those among heavy metals showed markedly different values. It was found that the main source of pollution of the Kumho river was the Third Industrial Complex, but the contribution of Palge should no be underestimated.

대구시 모 보건소에 내소한 성병환자에 대한 연구

윤능기,서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

The authors selected the medical records of the 2,346 diagnosed urethritis and syphilis patients from those who visited to a public health center in Taegue City, 1, January 1985 to 31, December 1987 to treat their urologic symptoms. Their medical records were used to investigate distribution status of the infection by demorgaphic and temporal variables. The results were as follows: 1. The most frequent age group was 20-29 years of age, 65.6%, and the less than 20 years of age group was 10.2%. In 30-39 age group, males 17.9% and females 23.0% and in 40-49 group, males 4.5% and females 12.2%. The female excess prevalence remained the same after that age group. 2. The order of relative frequency of the infection by month in which 3-year cases were combined was August, 11.3%, July 10.9%, January, 10.3% and the monthly distribution of the student was August, 16.0%, January, 11.6%, March, 10.7%, which suggests a coincidence with the periods of the school vacations. The seasonal distribution was summer 31.2%, spring 25.5%, autumn 21.7%, winter 21.5%. 3. The relative frequency of infection by martial status showed the unmarried was 70.3% and the married 29.37%, which was a significant difference. 4. The distribution by occupation was merchants 25.5%, office workers 19.2% and students 15.5% which was unexpectedly high. 5. In the distribution by source of infection of the males, friends was the most frequent source with 28.7%, restaurant employees 25.2%, prostitutes 16.8%, prostitutes 16.8%, and employees of lodging service 12.4%. 6. In the distribution by age and source of infection, friends were the most frequent source of infection(63.1%) in the less than 20 years of age group. In 20-29 years of age group, friends were 28.6%, restaurant employees 24.5%, prostitutes 17.8%, where showed increasing proportions of employees of the service trade. In 30-39 years of age group, restaurants employees 35.9%, employees of the lodging service 15.9%, prostitutes 14.9%, which means that most of sources of infection were employees of the service trade. In 4.-49 years of age group, restaurant employees 39.7%, prostitutes 17.2% and in 50-59 group, spouse was the most frequent(27.3%) and in the more than 60 years of age group prostitutes was 50%, but the total cases of that age group were too small to tabulate meaningfully. 7. The relative frequency of infection by infection history showed the inexperienced ws 48.4% and the experienced 51.6% and in the inexperienced, males 47.9% and females 78.1%.