혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

Quinlolone 유도체 국소도포에 의한 좌창치료의 임상적 연구

권철욱,노영석,김재홍,조소연,강형철,함정희 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.2

무선 ATM에서 ABR 서비스를 위한 MAC 프로토콜에 관한 연구

강상욱,윤정오,정종혁 경운대학교 산업기술연구소 2000 産業技術硏究論文誌 Vol.3 No.1(A)

In this paper, we describe a wireless MAC protocol named APRMA(Abitrary Period Reservation Multiple Access), which is capable of supporting the ABR type data service and maximizing channel utilization. In original PRMA protocol, data terminals with random data packets cannot reserve slot. That is, slot reservation is applicable too the time constraint voice packet exclusively. But the reservation scheme have to be performed for loss sensitive data packet, so data packets can get their quality of service. The aspects of service, if fixed bandwidth is allocated to data terminals, time constraint voice packets may have a low efficiency. So in this study, the terminal which wants to request for ABR type service, acquires a minimum bandwidth from system for the first time. If the system have extra available bandwidth, ABR terminals would acquire additional bandwidth slot by slot. As a result, APRMA protocol can support the data service with loss sensitivity and maintain their channel utilization highly. Also high priority services like voice can be satisfied with their QoS by APRMA

가토 발치와내에 이식된 자가 막성골과 자가 연골내 골화골의 조직반응에 관한 실험적 비교 연구

강정훈,김경욱 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

The purpose of this study was to compare the tissue response between the autogenous intramembranous bone and the autogenous endochondral bone grafted into the extraction socket of the rabbit. After the anterior teeth extraction, sockets were filled by the particulated cranial bone or by the particulated iliac bone. The rabbits were sacrificed at the 1st day, 3rd day, 1st week, 2nd week, 4th and 6th week after bone grafting. And the specimens were examined with light microscope. The results were as follows : 1. New bone formation with osteoblastic activity was observed on the cranial bone grafting area. 2. Trabecular patterns were shown in the 1st week specimen of the cranial bone grafting group, and were shown in the 2nd week specimen of the iliac bone grafting group. 3. 6th week after iliac grafting, maturation of endochondral bone with compact collagen deposition was observed. 4. 6th week after cranial bone grafting, compact bone pattern with dense fibrous tissue was observed.

腎皮質 電氣 燒灼法에 의한 白鼠 慢性 腎不全症 모델 誘導에 관한 硏究

정민수,김성숙,이강욱,신영태 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

An animal model with experimental uremia is an a important research tool for the study of sequence of pathological events taking place in uremic syndrome. A number of animal models and methods for the induction of chronic uremia have been published. The present study is designed to estabilish usefullness of a new method for the induction of chronic uremia in the rat. This method consist of unilateral destruction of most of the renal cortex by burns and contralateral nephrectomy. To investigate the results of massive renal ablation by this method, we measured serially blood pressure, body weight, BUN, serum creatinine, creatinine clearance, rate and examined renal histology. The results were as follows : 1) Surgical mortality rate was 5% and postoperative mortality of experimental group was 30.8% during 15 weeks of postoperative period. 2) Blood pressure of experimental group was significantly higher than control group after renal ablation(p<0.01). 3) Experimental group showed lower body weight gain than control group(p<0.01). 4) BUN and serum creatinine values increased continuously after renal ablation. However, those of control group were not changed. 5) Creatinine clearence rate of experimental group decreased significantly after renal ablation(p<0.01). 6) Weight of remnant kidney in experimental group was significantly higher than left kidney of control group(p<0.01). 7) Histologically, focal and segmental glomerular sclerosis, mesangeal proliferation, interstitial fibrosis and tubular atrophy appeared in the kidney of most experimental group 15 weeks after renal ablation. In conclusion, experimental rat group shows remarkable uremic appearance 7-11 weeks after renal ablation. This suggests that the unilateral renal cortical electrocoagulation and contralateral nephrectomy was a useful method for inducing experimental CRF rat model.

노인의 인구통계학적 특성이 여가활동유형에 미치는 영향

정명수,이강욱 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

This study alms to examine the relationship among the types of Leisure activities of the aged, their satisfaction with Leisure, their concentration on leisure and their loneliness. The subject of this study is the aged over 65 years old residing In Jeollanamdo and Gwangju by random sampling and total 520 subjects of 238 men (43.3%) and 282 women (51.3%) are used for the final analysis. The examination method accepts self-test recording and questionnaire to analyze the actual conditions and satisfaction of leisure through direct participation In the leisure program conducted by educational agencies for the aged and the statistical methods used for data analysis Include SPSS 10.0 for Windows, t-test and one-way ANOVA. This study obtains the four conclusions through the above methods and procedure as follows: First, It is found that the types of Leisure activities according to the demographical character Is tics of the aged are sports, health activities, hobby and cultural activities, amusement and social activities, there Is no statistical difference according to the presence of spouse, but there are difference in the types of Leisure activities enjoyed by the aged according to general characteristics. Second, it is known that there are statistically significant differences In the degree of subjective health, their satisfaction with pocket money and preparation for their old age and those who enjoy leisure activity show low loneliness, feel a considerable satisfaction with leisure and concentrate on the leisure activities.

광대역 CDMA 시스템을 위한 Transmit Adaptive Array와 전송 안테나 선택 다이버시티 결합 기법

강상욱,윤정오 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(A)

Transmit diversity schemes are an effective capacity improvement method for down link of Wideband Code Division Multiple Access (W- CDMA) systems. In this paper, we propose to use transmit antenna subset selection scheme in conjunction with closed loop Transmit Adaptive Array (TxAA). The proposed scheme selects N_s optimum antennas among N_T transmit antennas in order to maximize diversity gain from selected antennas, and also reduces the cost of RF chains by employing two different types of RF modules for the selected and the unselected antenna group. Under the same limitation on the amount of feedback information and feedback bandwidth as of the 3GPP specifications, the proposed scheme always outperforms the conventional closed loop TxAA with N_S antennas for all the mobile speeds. Moreover, the proposed scheme also shows better results than the TxAA with all the N_T antennas in realistic situations considering feedback delay, feedback bandwidth limitation and quantization.

경북 유학산, 천생산과 성암산 일대의 식물군락유형 분석

박강민,김종현,정현아,강치욱,이종운 嶺南大學校基礎科學硏究所 2002 基礎科學硏究 Vol.22 No.-

At the area of Yuhak, Cheonsaeng and Seongam mountains in Kyeongbuk, we studied the vegetation patterns with 75 plots on the base of Braun-Blanquet methods from March to October 2002. For the analysis of community patterns with 75 plots we used interspecies Affinity analysis method, DECORANA and TWINSPAN. The investigated area was divided into 17 communities with 177 species, and 20∼100% of treelayer, 10∼95% of shrublayer and 20∼100% of herblayer. By toe method of affinity analysis, it showed a big community with 86 species, but divided into 6 small groups by ordination and classification methods. Although it appeared as one group by the affinity test, the area divided into two groups by classification method at second level with eigenvalue of 0.320 and 0.430. It shows that the area of Yuhak, Cheonsaeng and Seongam mountains have own properties and in the process of succession.

적응적 비트평면 분할을 이용한 무손실 쿼드트리의 영상압축

윤정오,조영창,강상욱 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(B)

The transmission and storage of digital images require an enormous enpenditure of bandwidth and memory resources, necessitating the use of compression schemes can be divided into two categories : lossy coding schemes, and lossless coding schemes. In lossy coding schemes some portion of information is irretrievably lost, while in lossless coding schemes. However, the loss of information may not be acceptable in certain applications, such as transmission and storage of medical or scientific images, high-precision image, preservation of art work and historical documents. In this paper, we propose two lossless image compression methods using quadtree. this skill is composed of three steps : in the first step, we use predictive coding. at this course, we can choice the predictor what we want. Then, the second step, prediction error image be sliced by 1bit, 2bit, 4bit, 8bit. Last step, we apply quadtree coding. Experimental results show that the prpposed method (L-JPEG + GAP + quadtree combination method) is better than L-JPEG and close to GAP in compression ratio.

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.