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      • Landscape Ecological Study on the Habitats of Three Thalictrum Plants and its Distribution

        Kang,Shin-Ho,Ko,Sung-Chul 한국자원식물학회 2004 Plant Resources Vol.7 No.1

        The purposes of this study were to clarify of floristic composition and the landscape structure on the habitats of three Thalictrum plants, which were distributed in Daejeon, Korea. Floristic composition of habitats was organized by living in flatten open space needed a lot of sunlight and humidity. Landscape ecological structure of habitats was defined by soils of loamy skeletal mesic, slope between 25 to 30˚ Vegetation rating was 75 percent of woody coverage at less than 450 m above the sea levels, respectively. Distribution patterns of Thalictrum plants in Daejeon were presented on the 1 km X 1 km grid map.

      • KCI등재

        Cost Management of the K2 Main Battle Tank by Hyundai Rotem Company

        Kang,Ho Shin,Na,In Sung,Jung,DongSuk 韓國防衛産業學會 2008 韓國防衛産業學會誌 Vol.15 No.1

        현대의 전장상황은 네트워크전, 정보전, 로봇전, 우주전 등과 같이 고도로 정밀하고 복잡해짐과 동시에 장비 개발을 위해서 요구되는 비용은 기하급수적으로 급증하고 있는 추세이다. 그러므로 한정된 예산하에서 사업을 성공적으로 수행하기 위해서는 개발 초기부터 목표비용 설정 및 관리와 비용 절감 활동이 필수적으로 요구되고 있다.따라서 본 연구에서는 국방분야에서 추진하고 있는 비용관리 정책을 소개하고 K2 전차를 개발하면서 현대로템에서 적용한 목표비용 개념, 비용관리 절차 및 방법론을 제시하고 대표적인 비용절감 사례를 소개하고자 한다.

      • KCI등재

        Hydrogen Behavior in Ti-Added Reduced Activation Ferritic-Martensitic Steels

        Kang‑Mook Ryu,Dae Geon Lee,Joonoh Moon,Chang‑Hoon Lee,Tae‑Ho Lee,Jae Sang Lee,Dong‑Woo Suh 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.3

        Hydrogen behavior and corresponding mechanical degradation were examined in TaTi-RAFM and EUROFER97 steels. Increased Ta content with Ti addition decelerates the hydrogen diffusion but increases the solubility in the lattice. It ismainly led by the higher fraction of Ta-rich MC carbides and dislocation density in TaTi-RAFM steel. Overall activationenergy of hydrogen trapping of investigated steels is evaluated to be 25.3 ~ 25.6 kJ/mol in the tempered condition. The activationenergy increases to nearly 30 kJ/mol when the steels are re-austenitized and quenched. Higher activation energy withincreased dislocation density indicates that the dislocation provides for trap site with higher activation energy than Ta-richMC carbide. Mechanical degradation by hydrogen with respect to the yield strength, tensile strength and uniform elongationcould not be observed in all investigated steels. The presence of hydrogen only has influence on the loss of post-uniformelongation. For a given charging time, the loss of post-uniform elongation is more remarkable in TaTi-RAFM steel due tothe larger hydrogen uptake.

      • Flora of Mt. Woosanbong, Korea

        Kang,Shin-Ho,Lee,Young-Sim,Ko,Sung-Chul 한국자원식물학회 2003 Plant Resources Vol.6 No.1

        This study was performed to investigate the flora and plant resources of Mt. Woosanbong (537.8 m) from April to October 2002. The collected vascular plants were composed of all 389 taxa including cultivated species, and classified into 329 species, 2 subspecies, 53 varieties, and 5 forms of 248 genera under 81 families. Six taxa of the Korean endemic plants and 4 taxa of the rare and endangered plants were also distributed in this mount. Resource plants were categorized into edible 181, pasturing 160, medicinal 136, stainable 94, ornamental 77, timber 22, fiber 5 and industrial 4 taxa, respectively. Floristic geography of the investigated area was regarded as the boundary between middle and southern parts in floristic pattern of the Korean Peninsula.

      • Landscape Ecological Study on the Habitats of Genus Ranunculus Plants and its Distribution

        Kang,Shin-Ho,Ko,Sung-Chul 한국자원식물학회 2002 Plant Resources Vol.5 No.1

        The purposes of this study were to clarify of floristic composition and the landscape structure on the habitats of each Ranunculus plant, which were distributed in Daejeon, Korea. Three taxa were distributed and investigated in this study. Floristic composition of habitats were organized by living in flatten open space needed a lot of sunlight and humidity species. Landscape ecological structure of habitats were defined by soils of coarse loamy and loamy skeletal, slope of under 15$^{\circ}$ 수식 이미지, under the (five percent of woody coverage at 100-300m above the sea levels. Distribution patterns of Ranunculus plants in Daejeon were presented on the 1km X 1km grid map.

      • Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions

        Lee, Sang Choel,Han, Seung Hyeok,Li, Jin Ji,Lee, Sun Ha,Jung, Dong-Sub,Kwak, Seung-Jae,Kim, Seung Hye,Kim, Dong Ki,Yoo, Tae-Hyun,Kim, Jin Hyun,Chang, Se-Ho,Han, Dae Suk,Kang, Shin-Wook International Society of Nephrology 2009 Kidney international Vol.76 No.8

        Heme oxygenase-1 (HO-1) is an anti-oxidant enzyme normally upregulated in response to oxidant injury. Here we determined the role of HO-1 in podocyte apoptosis in glomeruli of streptozotocin-treated rats and in immortalized mouse podocytes cultured in media containing normal or high glucose. HO-1 expression, its activity, the ratio of Bax/Bcl-2 protein, and active caspase-3 fragments were all significantly higher in isolated glomeruli of diabetic rats and in high glucose–treated podocytes. These increases were inhibited by zinc protoporphyrin treatment of the rats or by HO-1 siRNA treatment of the podocytes in culture. The number of apoptotic cells was also significantly increased in the glomeruli of diabetic rats and in high glucose–treated podocytes. Inhibition of HO-1 accentuated the increase in apoptotic cells both in vivo and in vitro. Our findings suggest that HO-1 expression protects against podocyte apoptosis under diabetic conditions.

      • SCISCIESCOPUS

        Protective Effect of Baicalin Against Carbon Tetrachloride–Induced Acute Hepatic Injury in Mice

        Park, Sang-Won,Lee, Chan-Ho,Kim, Yeong Shik,Kang, Sam Sik,Jeon, Su Jin,Son, Kun Ho,Lee, Sun-Mee The Japanese Pharmacological Society 2008 JOURNAL OF PHARMACOLOGICAL SCIENCES Vol.106 No.1

        <P>This study examined the effects of baicalin, a bioactive flavonoid isolated from <I>Scutellariae Radix</I>, on carbon tetrachloride (CCl<SUB>4</SUB>)-induced liver injury. Mice were treated intraperitoneally with 0.5 ml/kg CCl<SUB>4</SUB> and different groups of animals received 25, 50, 100, and 200 mg/kg baicalin. At 24 h after the CCl<SUB>4</SUB> treatment, the level of serum aminotransferases and lipid peroxidation was significantly elevated, whereas the hepatic glutathione content was decreased. These changes were attenuated by baicalin. The histological studies showed that baicalin inhibited the portal inflammation, centrizonal necrosis, and Kupffer cell hyperplasia, which are the three most common characteristics of CCl<SUB>4</SUB>-induced liver damage. The serum level and mRNA expression of tumor necrosis factor-α were markedly increased by the CCl<SUB>4</SUB> treatment but suppressed by baicalin. The mRNA and protein expression levels of inducible nitric oxide synthase and heme oxygenase-1 increased significantly at 24 h after the CCl<SUB>4</SUB> treatment. Baicalin attenuated the increase in the protein and gene expression of inducible nitric oxide synthase but augmented the increase in those of heme oxygenase-1. These findings suggest that baicalin protects hepatocytes from the oxidative damage caused by CCl<SUB>4</SUB>, and this protection is likely due to the induction of HO-1 expression and the inhibition of the proinflammatory mediators.</P>

      • KCI등재

        성인 쇄골 간부 골절에서 두 가지 수술적 치료군 간의 결과 비교: 금속판을 이용한 관혈적 정복 및 내고정술과 Steinmann Pin을 이용한 경피적 겸자 정복 및 골수강내 고정술의 결과 비교

        허성식 ( Sung Sik Ha ),심재천 ( Jae Chun Sim ),홍기도 ( Ki Do Hong ),김재영 ( Jae Young Kim ),강정호 ( Jung Ho Kang ),박광희 ( Kwang Hee Park ) 대한골절학회 2007 대한골절학회지 Vol.20 No.3

        목적: 성인 쇄골 간부 골절에서 금속판을 이용한 관혈적 정복 및 내고정술과 Steinmann pin을 이용한 경피적 겸자 정복 및 골수강내 고정술의 결과를 분석하여 비교하였다. 대상 및 방법: 2002년 3월부터 2006년 1월까지 본원에서 치료한 총 68예의 쇄골 간부 골절을 대상으로 하였으며, 금속판을 이용한 33예, Steinmann pin을 이용한 35예의 치료 결과를 분석하였다. 최종 결과 판정은 강 등의 기준에 의한 임상적 결과와 방사선학적 골유합 기간으로 하였고, 수술 시간을 비교하였다. 결과: 임상적 결과는 우수 이상의 예가 금속판을 이용한 군의 경우 총 33예 중 29예로 88%, Steinmann pin을 이용한 군의 경우 총 35예 중 32예로 91%의 결과를 보였다. 방사선학적 골유합 시기는 각각 평균 8.9주와 9.1주였고, 수술 시간은 금속판 군에서 평균 72분, Steinmann pin 군에서 평균 18분이었다. 결론: 성인 쇄골 간부 골절의 치료에 있어 금속판을 이용한 수술 군과 Steinmann pin을 이용한 수술 군은 임상적, 방사선학적 결과 면에서 통계학적으로 큰 차이를 보이지 않았으나, Steinmann pin을 이용한 수술 군에서 수술 시간 및 회복기간의 감소로 인하여 경제적인 면과 수술반흔의 감소에 따른 미용적인 면에서 더 만족스런 결과를 보였다. Purpose: To evaluate the results between open reduction and internal fixation with the plate and percutaneous reduction by towel clip and intramedullary fixation with Steinmann pin for clavicle shaft fractures in adult. Materials and Methods: We have studied the results in 33 cases with the plate. 35 cases with the Steinmann pin among total 68 cases of clavicle shaft fracture. The patients were followed up over a period of at least 12 months. The final postoperative outcome was analyzed with the clinical outcomes using Kang`s criteria. radiological union time and operation time. Results: The clinical outcome that was good or excellent according to the Kang`s criteria showed a distribution of 88% in the group using the plate with 29 cases out of total 33 cases. 91% in the group using the Steinmann pin with 32 cases out of total 35 cases. The mean radiological union time was 8.9 weeks in the group using the plate. 9.1 weeks in the group using Steinmann pin. The mean operation time was 72 minutes in the group using the plate, whereas was 18 minutes in the group using Steinmann pin. Conclusion: In the treatment of adult clavicle shaft fracture. two groups did not show a significant statistical difference in clinical and radiological outcomes. However, the operation time and postoperative functional recovery was significantly shorter and faster in the group using Steinmann pin. Additionally economic and cosmetic aspect was more satisfactory in the group using Steinmann pin.

      • KCI등재후보

        Effects of dietary supplementation with probiotic CS-A on performance in broiler chickens

        Seong Soo Kang1*, Se Eun Kim, Ara Go, Kyung Mi Shim, Chun Sik Bae, Chang Jong Moon, Sung-Ho Kim, Jong-Choon Kim, Jin-Cheol Yoo, Seung Sik Cho 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

        Probiotics, enzymes, organic acids, oligosaccharides, antioxidants, and other functional materials are actively being explored as alternatives to antibiotics. Probiotics include live beneficial microorganisms that colonize the intestinal tract and competitively inhibit attachment and growth of harmful microbes. Probiotics also increase feed efficiency by assisting in nutrient absorption and digestion. The current study was conducted in order to evaluate the effect of a new probiotic, CS-A, as a dietary supplement of a fermented product on growth performance, feed intake, and feed conversion efficiency in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Antibacterial and anti-inflammatory effects of CS-A were investigated in vitro and the in vivo effects of a constant concentration of supplemented CS-A on growth rate and feed efficiency were evaluated. In addition, the safety of CS-A was assessed by examination of common symptoms and mortality. Determination of minimal inhibitory concentration revealed an excellent antibacterial effect of CS-A. Cytotoxicity was low and anti-inflammatory effects were achieved at the effective concentration of CS-A. Supplementation with 0.1% CS-A resulted in a feed efficiency score of 1.84 in broilers, compared to 2.00 in the control group. There were no adverse clinical findings, necropsy findings, hematology, and altered serum biochemistry parameters, and no mortality. Thus, it is concluded that CS-A is safe and effective as a feed additive.

      • SCIESCOPUSKCI등재

        Regulatory Roles of Chrysanthemum zawadskii Roots in Nuclear Factor E2-related Factor 2/Antioxidant Response Element Pathway

        Hye-Sook Kang,Min-Ji Park,Kyong-Suk Jin,Young-Hun Kim,Mira Jun,Ho-Jin Lim,Wan-Kuen Jo,Jong-Sang Kim,Woo-Sik Jeong 한국식품과학회 2008 Food Science and Biotechnology Vol.17 No.2

        Cellular protection against carcinogens could be achieved by the induction of phase 2 detoxifying and antioxidant enzymes such as glutathione S-transferase (GST), NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1). Nuclear transcription factor E2-related factor 2 (Nrf2) binds to antioxidant response element (ARE) in the promoter region of these genes and the resulting transactivation occurs. In the present study the effect of gujeolcho (Chrysanthemum zawadskii) roots on the Nrf2-ARE pathway were investigated. C. zawadskii root extract was fractionated with a series of organic solvents and their ability to induce Nrf2-ARE pathway was examined. We separated the most potent dichloromethane (DCM) fraction into 12 sub-fractions and found several sub-fractions with strong effects on the Nrf2-ARE pathway. Fraction 4 strongly induced the ARE-reporter gene activity as well as Nrf2 expression. Sitosterol was isolated as a major compound in fraction 4 although its activity was not as potent as its mother fraction. These results indicate that C. zawadskii roots might be used as a potential natural chemopreventive source.

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