사료중 Blended Essential Oil(CRINA^(�)) 첨가가 육계의 생산성과 영양소 이용률, 소장 내 미생물 균총 및 계육내 지방산 조성에 미치는 영향

석종찬,임희석,백인기 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.5

An experiment was conducted to investigate the effects of supplementary Blended essential oil(CRINA^(�)) on the performance, nutrient availability, fatty acid composition of leg muscle, small intestinal microflora and blood parameters in broiler chickens. One thousand unsexed day-old broiler chickens were assigned to five treatments : control(T1), 5? avilamycin(starter diet) & 5? flavomycin(grower diet) T2, 5? avilamycin(starter diet) & 50? CRINA^(�)(grower diet) T3, 50? CRINA^(�)(starter & grower diet) T4, 50? CRINA^(�) +500? lactic acid^(�) (starter & grower diet) T5. Each treatment had four replications of 50 birds each. Growth performance was significantly improved by dietary supplements(T2-T5). There were no significant differences among treatment T2, T3, T4 and T5. Feed intake was not significantly different among treatments. Dietary supplementation of CRINA^(�) (T3, T4, T5) resulted in significant(p<0.05) improvement in feed/gain(F/G) during finishing period (4-5 weeks). The birds fed CRINA^(�) supplemented diet(T4) showed significantly(p<0.05) higher availability of crude fat, menthionine and methionine + cystine than those fed antibioties supplemented diet(T2). Mortality was not significantly affected by treatments. The colony forming unit(CFU) of E. coli in small intestinal content was significantly lower in antibioties & CRINA^(�)(T3) compared to CRINA^(�) treatment(T4)(P<0.05). CFU of CI. perfringens was low in CRINA^(�)(T4) but not different significantly with other treatments. Serum triglyceride level of birds fed CRINA^(�) + lactic acid diets(T5) was significantly lower(p<0.05) than those fed antibiotics supplemented diet(T2). Cholesterol level of the birds fed antibiotics(T2) or CRINA^(�) + lactic acid supplemented diet(T5) was significantly higher(p<0.05) than other treatments. HDL level of birds fed control diet was significantly lower(p<0.05) than that of others. The levels of serum IgG were not significantly different among treatments. Major fatty acids composition of leg muscle fat was significantly influenced by treatments. Control group showed significantly higher palmitic acid(C_(16:0)) and steraric acid(C_(18:0)) content than other treatments(p<0.05). Content of oleic acid(C_(18:1)), however, was significantly lower in the control than others treatments. Content of linolenic acid(C_(18:3)) was significantly higher in CRINA^(�) + lactic acid(T5) than antibiotics & CRINA^(�)(T3) treatments. Total saturated fatty acids content was higher and total unsaturated fatty acids were lower in the leg muscle fat of the control than that of other treatments. It is concluded that CRINA^(�) supplementation improved growth rate and F/G ratio in broilers. The combination of CRINA^(�) with either antibiotics or lactic acid did not show any additive or synergistic effects in broiler chickens.

아급성 갑상선염의 임상적 고찰

홍기석,고창순,정준기,이홍규,김삼용,석창호,박성회,김용일 대한핵의학회 1978 핵의학 분자영상 Vol.12 No.2

저자들은 서울대학교 병원 내과에서 108례의 갑상선 침생검을 시행하여 8례(7.9%)의 아급성갑상선염을 진단할 수 있었다. 이를 임상경과, 갑상선기능 등으로 본 임상단계와 비교한 결과 다음과 같은 결론을 얻었다. Czernick 등이 시도하였던 임상단계와 침생검의 조직소견이 비교적 잘 대응하였다. 임상경과가 길거나 갑상선기능이 낮을수록 갑상선의 섬유화가 심하였고 여포성분의 감소를 보였다. 갑상선의 기능상태와 옥소섭취율 혹은 갑상선주사상의 섭취율은 역 상관관계를 보였다. 임상단계의 초기에 발견된 환자들은 기능항진증의 증상을 보였다가 기능저하증의 양상을 보인 후 회복되는 이형적인 경과를 보였다. 임상단게의 후기에 발견된 환자들은 4명중 3명이 기능저하증을 보였는데, 이는 경과로 보아 질환의 최종단계로 생각되었다. $quot; 8 cases of subacute thyroiditis was diagraiosed amormg 108 needle biopsy of the thyroid during the period from April 1976 to August 1978. Correlation of the histologic findings with the clinical staging proposed by Czernick was relatively well matched; cases with long clinical course or low thyroid hormone levels showed greater fibrosis and reduction of follicular elements in thyroid. Thyroid (131)^I uptake or the uptake as seen on the thyroid scanning correlated inversely with the thyroid hormone levels. The clinical course of the patients seen in their initial stage of disease followed the classical pattern; hyperthyroid-like, hypothyroid-like and recovery. 3 among the 4, who were seen in their later clinical course showed hypothyroidism, which seemed the final outcome of their diseases.

SA350 LF3 강 수송용기의 동적파괴인성평가

김국철(K.C. Kim),석진익(J.I. Suk),권희경(H.K. Kwon) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.11

A spent nuclear fuel cask should safe in the case of most severe accident loading during transportation. Therefore, in order to verify the integrity of the shipping cask manufactured by doosan heavy industries for the first time in Korea, rapid loading K1C tests has performed as material property evaluation. In this paper, the dynamic fracture toughness obtained by rapid loading K<SUB>IC</SUB> tests is discussed. The procedure of the integrity evaluation of the shipping cask is as follow: First, the maximum flaw size for the full area of forging product of the shipping cask is measured by nondestructive examination. Second, the dynamic fracture toughness test is carried out at -40℃. Third, FEM is performed for the model of the shipping cask with the maximum size flaw measured by NDE under seismic loading. Finally, the integrity of the shipping cask is evaluated by comparing maximum stress intensity factor calculated by FEM with dynamic fracture toughness measured by the experiment. In the integrity evaluation, our company has carried out nondestructive examination and dynamic fracture toughness test, and GNB Company in Germany has carried out FEM analysis. From the evaluation, the integrity of shipping cask was confirmed.

클러스터 중심 왜곡 저감을 위한 클러스터링 기법

정혜천(Hye C. Jeong),서석태(Suk T. Seo),이인근(In K. Lee),권순학(Soon H. Kwon) 한국지능시스템학회 2008 한국지능시스템학회논문지 Vol.18 No.3

클러스터링은 주어진 임의의 데이터 중에서 유사한 성질을 지닌 데이터를 복수개의 그룹으로 조직화하는 기법이다. 이를 위해 K-Means, Fuzzy C-Means(FCM), Mountain Method(MM) 등과 같은 많은 기법들이 제안되었고 또한 널리 사용되어 지고 있다. 그러나 이러한 기법들은 초기값에 따라 클러스터링 결과가 크게 달라지는 단점이 있다. 특히 가장 널리 사용되는 FCM 기법은 잡음 데이터에 취약하며, 주어진 입력 데이터의 클러스터 내부분산을 최소화 하는 방법을 사용하기 때문에 클러스터링 중심의 왜곡 현상이 발생한다. 본 논문에서는 데이터 가중치에 근거한 비례적 근접데이터 병합을 통하여 클러스터 중심 왜곡을 저감하며 초기값에 영향을 받지 않는 클러스터링 기법을 제안한다. 그리고 FCM으로 얻어진 클러스터 중심과 제안기법을 적용하여 얻어진 클러스터 중심에 대한 비교 검토를 통하여 제안기법의 효용성을 확인한다. Clustering is a method to classify the given data set with same property into several classes. To cluster data, many methods such as K-Means, Fuzzy C-Means(FCM), Mountain Method(MM), and etc, have been proposed and used But the clustering results of conventional methods are sensitively influenced by initial values given for clustering in each method. Especially, FCM is very sensitive to noisy data, and cluster center distortion phenomenon is occurred because the method dose clustering through minimization of within-clusters valiance. In this paper, we propose a clustering method which reduces cluster center distortion through merging the neal-est data based on the data weight, and not being influenced by initial values. We show the effectiveness of the proposed through experimental results applied it to various types of data sets, and comparison of cluster centers with those of FCM.

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent.

Krishnan, Navasona,Jeong, Dae Gwin,Jung, Suk-Kyeong,Ryu, Seong Eon,Xiao, Andrew,Allis, C David,Kim, Seung Jun,Tonks, Nicholas K American Society for Biochemistry and Molecular Bi 2009 The Journal of biological chemistry Vol.284 No.24

<P>In mammalian cells, the DNA damage-related histone H2A variant H2A.X is characterized by a C-terminal tyrosyl residue, Tyr-142, which is phosphorylated by an atypical kinase, WSTF. The phosphorylation status of Tyr-142 in H2A.X has been shown to be an important regulator of the DNA damage response by controlling the formation of gammaH2A.X foci, which are platforms for recruiting molecules involved in DNA damage repair and signaling. In this work, we present evidence to support the identification of the Eyes Absent (EYA) phosphatases, protein-tyrosine phosphatases of the haloacid dehalogenase superfamily, as being responsible for dephosphorylating the C-terminal tyrosyl residue of histone H2A.X. We demonstrate that EYA2 and EYA3 displayed specificity for Tyr-142 of H2A.X in assays in vitro. Suppression of eya3 by RNA interference resulted in elevated basal phosphorylation and inhibited DNA damage-induced dephosphorylation of Tyr-142 of H2A.X in vivo. This study provides the first indication of a physiological substrate for the EYA phosphatases and suggests a novel role for these enzymes in regulation of the DNA damage response.</P>

생약제제(미라클^(�))첨가가 이유 자돈의 성장률, 영양소 이용율, 분내 미생물균총 및 면역기능에 미치는 영향

석종찬,임희석,백인기 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.5

An experiment was conducted to investigate the effects of dietary herbal product(Miracle^�) supplementation on the performance, nutrient digestibility, fecal microflora and blood parameters in pigs. Forty eight cross bred(Y×L×D) weanling pigs (average initial body weight 7.84㎏±0.17, 28 d old) were used in 35 d feeding trial. Pigs were allotted to 16 raised floor cages(W 35.5㎝ × L45㎝ ×H55㎝). EAch treatment had four replications of 3 pigs each. Treatments were: control (T1), CTC 100? (T2), Miracle^� 0.15% (T3) and CTC 100? + Miracle^� 0.15% (T4). The herbal product supplementation(T3) tended to improve the weight gain, feed intake, feed/gain but there were no significant differences among treatments. Nutrient digestibility was significantly(P<0.05) affected by dietary treatments. The pigs fed T3 diet showed the lowest digestibility of DM, crude protein, NFE, P, and amino acids among treatments. Serum cholesterol level of pigs fed T3 diet was lowest and significantly(p<0.05) lower than those fed antibiotic supplemented diet(T2). Triglyceride and HLL level of the pigs fed T3 diet were also lower than those of others but the differences were not significant. The level of serum IgG was significantly(p<0.05) different among treatments. The level of serum IgG was highest in T4, followed by T1, T2 and T3. Serum AST(Aspartate aminotransferase) level of the control(T1) was lower than other treatments. Levels of serum total protein, albumin and ALT(Alanine aminotransferase) were not significantly different among treatments. The colony forming units (CFU) of Lactobacillus. CI. perfringens and E. coli in feces were not significantly different among treatments but those of CL. perfringens of T2 (CTC 100?) showed the lowest count at both 3rd and 5th wk. It is concluded that herbal product Miracle?) does not significantly affect growth performance of weanling pigs but it influenced the digestibility, serum IgG, cholesterol and AST level. The combination of the herbal product Miracle^� with antibiotic(CTC) showed no synergistic effects.

Gilles de la Tourette氏 病의 1例

石在鎬,尹昌範,李根厚,高炳鶴,權吉祐 大韓神經精神醫學會 1971 신경정신의학 Vol.10 No.1

The authors report A Case of Gilles de la Tourette's Syndrome seen in 20 years old man. The manifesting syndromes were controlled with Neuroleptics(Perphenazine, Chlorpromazine), Meprobamate and regular psychiatric interview on the basis of hospitalized. The several literiture are reviewed and clinical aspects of this syndrome are discussed.

외래 환자에서의 정신증상과 월경주기간의 상호관계

안석철,석재호,이규항 大韓神經精神醫學會 1972 신경정신의학 Vol.11 No.3

The authors studied the menstual histories of 100 patients who had sought psychiatric help in order to determine the phase in which they came for help. A total of 100 selected patients were screened in the emergency room and the out patient department of neuropsychiatry of the Sacred heart hospital and Han Gang Sacred heart hospital, College of Medicine, Chung Ang University from Jan. 1. to Apr. 31, 1972. 27 being seen in the Emergency Room & 73 being in the out patient department. The results are following: 1. The seeking of psychiatric help by these 100 patients was found to occur most frequently during midcycle period (21 percent), followed by premenstrual phase (20 percent) and the menstruation (19 percent). 60 percent of our patients came to the hospital for psychiatric help during one of these three phases. 2. In the Emergency Room, patient's help was sought most frequently during the menstruation. It's findings was similar to those of Dalton for psychiatric admission. 3. In the out patient department, it was during the midcycle period (21.9 percent) that most visits were made, followed by the premenstrual period(21 percent), post menstrual period(5-8th day) (17.8 percent) and menstruation (13.5 percent). 4. The author, therefore, guessed that there was the relationship between the phases of the menstrual cycle & the development of psychiatric symptoms. In any case, further study of the frequency with which menstruation acts as a precipitating factor in psychiatric symptoms would seem to be indicated.

Structural and Optical Characterization of Ge Nanocrystals Showing Large Nonvolatile Memories in Metal-Oxide-Semiconductor Structures

Sung Kim,Suk-Ho Choi,C. J. Park,H. Y. Cho,K. H. Cho,R. G. Elliman 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.3

The structural and the optical properties of Ge nanocrystals (NCs) showing large capacitancevoltage hysteresis have been studied by using infrared photoluminescence (PL), high-resolution transmission electron microscopy (HRTEM), high-resolution X-ray diraction (HRXRD). The memory eect strongly depends on the implant dose, the oxide thickness, and the annealing temperature in metal-oxide-semiconductor devices containing Ge NCs. Well-defined C-V characteristics with large hysteresis are found only for annealing temperatures 950 C where Ge NCs are known to form. HRTEM demonstrates the existence of Ge NCs which are almost aligned at an average distance of about 6.7 nm from the SiO2/Si interface. This suggests that the memory eect can be enhanced by accurately controlling the distribution of Ge NCs with respect to the Si/SiO2 interface, although it is also influenced by implantation-induced deep-level defects and SiGe complexes formed at the interface, as confirmed by PL and HRXRD.

레이저 표면열처리가 Zircaloy-4 합금의 산화에 미치는 영향

한정호,임갑순,석호천,정용환,이덕현 대한금속재료학회(대한금속학회) 1988 대한금속·재료학회지 Vol.26 No.8

The effect of heat treatment on the oxidation behavior of Zircaloy-4 plates was investigated in 400 to 600℃ steam for alpha-annealed, beta-quenched, and laser surface beta-treated samples. It was observed that the laser treatment resulted in the formation of surface layer of 40∼50㎛ thick beta-treated structure on the mass of alpha-annealed plates, and the microstructure of laser treated layer was much finer than those of alpha-annealed and beta-quenched samples. The corrosion resistance of laser treated Zircaloy was found to be superior to other two samples in a1l the temperatures. At 600 ℃, the corrosion rate was changed from cubic (W=kt^(1/3)) to linear rate(W=kt) after about 7 hour exposures. The marked improvement in corrosion resistance of laser treated samplers is thought to be due to the change of the second phase particle distribution. The coarse and discrete particles in the alpha-annealed structure changed to the fine and chain-like particles in the laser heat treated samples. In this study, the structure of oxide layer was observed to be only one type of monoclinic ZrO₂.