건설비 절감을 위한 고무차륜 경량전철 상하식분기기 개발 (Development of Up-Down Turnout System of AGT for Reduction of Construction costs)

차정권(Kwon-Jung Cha),윤일로(Il-Ro Yoon),김동활(Dong-Howal Kim),후쿠모토(Yozo Fukumoto) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.5

Light Rail Vehicle(LRT) is “New Transit System” that has transportation capacity as well as physical size of vehicle is in-between bus and subway. The demand of LRT system is increasing rapidly; both domestically and internationally. Reason being is that it is more economical and eco-friendly compare to existing heavy rail vehicle. Especially, Busan Subway Line 4 K-AGT (Rubber-tired LRT) being the first of its kind to start revenue service in Korea, it is very much likely that application of its demand will continue to increase. Considering its trend, study to reduce implementation cost of LRT is being pursued in many different aspects; reducing construction cost is one that aspect. In this study, on-site application of ‘Up-Down Turnout System’ implementation research has been carried out which can replace existing ‘Left-Right Turnout System’. When safety of its type gets verified, application of this system to line which intends to use K-AGT, Shin-Lim Line and Dong-Book Line, expects to save its construction cost. This thesis paper reports ongoing research of AGT ‘Up-Down Turnout System’ development and main component design factors, fundamental principle, performance test result.

Ⅴ. 속담(俗談)ㆍ수수께끼편

임동권(Im Dong-Kwon),박현국(Park Hyun-Kook),김정원(Kim Jung-Won),장정순(Jang Jong-Soon) 중앙대학교 한국문화유산연구소 1995 중앙민속학 Vol.- No.7

신경회로망 제어기를 이용한 PID 파라미터 추정에 관한 연구

權重東,裵銀敬,金恩基,全基英,李承桓,吳鳳煥,李勳九,金容珠,韓慶熙 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

In this paper, supposed to solve these problem to PID parameters controller algorithm using ANN. In the proposed algorithm, the parameters of the controller were adjusted to reduce by on-line system the error of the speed of IM. In this process, EBPA NN was constituted to an output error value of an IM and conspired an input and output. The performance of the self-tuning controller is compared with that of the PH) controller tuned by conventional method (Ziehler-Nichols). The effectiveness of the proposed control method is verified thought the Matlab Simulink and experimental results.

主觀的인 評價에 의한 靑少年의 肥滿傾向 分析

權善鈺,金基學,李東洙,鄭鎭國 慶北大學校 師範大學 體育學硏究會 1992 體育學會誌 Vol.20 No.-

This study was conducted to analyze the tendency of obesity by subjective evaluation method in measuring the skinfold thickness in adolescents. The validity norms were height, weight, the sum of skinfold thickness, Db1, %Fat1, %Fat2, and BMI. The subjects surveyed were 2,442 boy and girl students of middle and high school in medium and small city and big city. The results are summarized as follows; 1. Weight of adolescents evaluated as obesity was over 76㎏ in boy's middle, over 67㎏ in gril's middle school, over 79㎏ in boy's high school, and over 68㎏ in girl's high school, the sum of skinfold thickness was over 40㎜, over 39㎜, over 54㎜, and over 41㎜ respectively. 2. Except the case of height in girl's middle, boy's high and girl's high school, in height in boy's middle, weight, the skinfold thickness, Db1, %Fat1, %Fat2, and BMI, difference among the degree of obesity evaluated subjectively was significant(p<.05). 3. Except heigh in girl's middle, boy's and girl's high school, correlation between the degree of obesity evaluated subjectively and height in girl's middle school, weight, the sum of skinfold thickness, Db1, %Fat1, %Fat2, BMI respectively was high and significant(p<.01 or p<.001) Therefore, on the basis of above results, I think we can evaluate the tendency of obesity in adolescents validly by subjective evaluation method as well.

몇 가지 항진균제가 Aspergillus fumigatus에 의한 대식세포의 Cytokine 생산에 미치는 영향

권은영,박철민,박선희,최수미,이동건,유진홍,신완식,최정현 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

배경 : 현재 임상에서 사용되는 서로 다른 계열의 항진균제가 면역세포인 폐 대식세포(alveolar macrophage)에서의 cytokine 생산과 nuclear factor- κB (NF- κB)활성에 미치는 영향을 시험관내에서 파악하고 그 의미를 추론해 보고자 하였다. 재료 및 방법 : AmB, MF, ITZ 등 세 가지 항진균제가 쥐의 폐 대식세포인 RAW264.7 세포의 생존에 미치는 영향과, 이들 항진균제의 전처치가 Aspergillus fumigatus conidia 자극에 의한 RAW264.7 세포에서의 TNF-α, IL-10 생산, NF-κB 활성에 미치는 영향, 그리고 GMCSF와의 상승 작용 등을 WST-1, ELISA, western blot assay를 이용해 통해 측정하였다. 결과 : AmB, MF, ITZ 모두 농도 의존적으로 RAW264.7 세포의 생존을 감소시켰다. A. fumigatus conidia 자극으로 RAW264.7 세포에서 TNF-α 생산이 증가하였으며, 세포 생존에 영향을 미치지 않는 농도의 AmB를 전처치하고 conidia로 자극한 경우 TNP-α 생산에는 차이를 보이지 않았으나, MF와 ITZ을 전처치한 경우에는 TNF-α 생산이 감소하였다. GM-CSF는 AmB 전처치 및 A. fumigatus conidia 자극에 의한 TNF-α 생산에 상승 효과를 보였으나, MF, ITZ은 GM-CSF에 의한 상승 효과를 보이지 않았다. IL-10은 AmB에 의해 생산량이 증가하였으며 GM-CSF와 동시 투여시 IL-10 생산이 유의하게 상승하였다. MF와 ITZ 역시 RAW264.7 세포에서 IL-10 생산을 유도하였으나 AmB에 비해 상승폭이 적었으며 GM-CSF와의 상승 효과는 관찰되지 않았다. A. fumigatus conidia는 NF- κB를 활성화하였으며 항진균제와 GM-CSF 등 약제 처치에 따른 NF-κB의 활성 정도는 분비된TNF-α와 IL-10의 생산 정도와 상관관계를 보였다. 결론 : AmB, MF, ITZ 등 본 연구에 사용된 항진균제는 시험관내에서 A. fumigatus conida로 자극하는 RAW264.7 세포에 전처치함으로써 염증성 cytokine인 TNF-α의 생산을 감소시키고 항염증성 cytokine인 IL-10의 생산을 증가시키는 면역 조절 효과를 나타낼 수 있음이 관찰되었다. 추후 약제간의 면역조절 기능 차이가 항진균효과에 미치는 영향 및 약제에 따른 면역 조절 경로 등에 대한 연구가 필요할 것으로 사료된다. Background : We wanted to evaluate the immunomodulatory effect of three antifungal agents, amphotericin B (AmB), micafungin (MF), itraconazole (ITZ), in the aspect of cytokine production and expression of nuclear factor-κB (NF-κB) in the Aspergillus fumigatus conidia treated-RAW264.7 cells, a murine alveolar macrophage cell line. Materials and Methods : We evaluated cytotoxic effect of antifungal agents using commercial cell proliferation assay. Tumor necrosis factor (TNF)-α and interleukin (IL)-10 production according to stimulation (control, A. fumigatus conidia only, conidia + antifungal drug, conidia + antifungal drug + GM-CSF) was evaluated and compared each using commercial ELISA method. NF-κB activation was evaluated by western blot analysis. Results : AmB, MF, ITZ showed dose-dependent cytotoxic effect on the tested cells. Stimulation of cells by A. fumigatus conidia induced TNF-α production. Pretreatment of AmB at concentration not affecting cellular survival did not change the production of TNF-α compared to conidia treated cells, but pretreament of MF or ITZ showed reduced amount of TNF-α production compared to conidia treated cells. AmB also showed synergistic effect on TNF-α production when simultaneously treated with GM-CSF. IL-10 production was markedly increased when the cells were treated with AmB with conidia. MF and ITZ induced less increase of IL-10 production than AmB. AmB also showed synergistic effect on the production of IL-10 when treated with GM-CSF simultaneously. A. fumigatus conidia enhanced expression of NF-κB. The degree of NF-κB expression was associated with the amount of TNF-α and IL-10 produced. Conclusion : The antifungal agents we used in this experiment showed that decreased TNF-α production and increased IL-10 production from the RAW264.7 cells stimulated by A. fumigatus conidia after pretreatment of antifungal agents. But more studies, such as the association between immunomodulatory effect, antifungal activity and difference of signal pathway of cellular activation according to drugs should be performed.

경피적 자궁동맥 색전술로 치료한 산후 출혈 1례

정명철,김호성,김경철,노지현,고재환,김용봉,권동일 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Postpartum hemorrhage remains one of the leading causes of maternal deaths. The major causes of postpartum hemorrhage include uterine atony, retained placental fragment, placenta accreta, and lower genital tract lacerations. Conservative treatment is based on administration of uterotonic drugs, vaginal packing, and surgical repair of genital tract lacerations. When bleeding fails to respond to conservative treatment, surgical ligation of uterine vessels or hemostatic hysterectomy is performed. We present a case of postpartum bleeding treated by selective uterine arterial embolization with a brief review of previous literatures of postpartum hemorrhage & uterine arterial embolization.

후방순환계 뇌동맥류의 임상분석

임동준,이훈갑,정흥섭,김봉룡,권택현,이기찬,서중근 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.11

국내 혈액질환 환자에서 침습성 아스페르길루스증의 구제치료로서 Voriconazole의 효과와 안전성

권재철,김시현,최수미,최재기,이동건,박선희,최정현,유진홍,신완식 대한감염학회 2010 감염과 화학요법 Vol.42 No.1

Background: Invasive aspergillosis (IA) is associated with significant morbidity and mortality in patients with hematologic malignancies. We investigated the efficacy and safety of voriconazole (VCZ) when used as salvage therapy for IA in Korean adults with hematologic malignancies who had not responded to prior antifungal therapy. Materials and Methods: We retrospectively reviewed data, collected from January 2007 to October 2008, from patients with proven or probable cases of IA. All were probable IA cases, except for one proven case. All cases were refractory or intolerant to antifungal therapy prior to administration of VCZ. Efficacy and safety were assessed in patients treated with VCZ for more than 3 days and for more than one dose, respectively. A favorable response [complete (CR) or partial (PR)] was defined by significant improvement of all clinical symptoms, signs, and radiologic abnormalities. Results: Fifty patients who met the inclusion criteria were enrolled. There were 27 male and 23 female patients with mean age of 44.4 years (range, 15-65 years). Underlying diseases were acute leukemia (35 cases), chronic myelogenous leukemia (4 cases), myelodysplastic syndrome (3 cases), lymphoma (3 cases) and other hematologic diseases (5 cases). Twenty-two patients had received chemotherapy and 13 patients had undergone hematopoietic stem cell transplantation. The lung was the main infection site (94%) followed by the sinus (6%). Amphotericin B deoxycholate alone was the most frequent previous antifungal therapy. The mean duration of antifungal therapy prior to VCZ therapy was 13.9±8.8 days (2-44 days). The median duration of VCZ therapy was 19 days (interquartile range, 49 days). Sixteen patients (32.0%) showed favorable responses (CR:PR=8:8) at the end of VCZ therapy. The numbers of patients with stable disease, progression and death were, 6 (12%), 6 (12%) and 22 (44%) respectively. Most of those with unfavorable responses had relapsed underlying malignancies or refractory graft versus host diseases. Twelve patients developed drug-related adverse events but only one patient stopped VCZ treatment prematurely. Conclusions: VCZ demonstrated an acceptable level of toxicity in patients with hematologic malignancies but further studies are required to prove its efficacy as salvage therapy.

음향방출을 이용한 저어널 베어링의 조기파손감지(Ⅱ) : Part Ⅱ : Intervention of Foreign Particles in Lubrication 윤활유 이물질 혼입의 영향 및 감시

권오양,윤동진,김경웅,정민화 韓國非破壞檢査學會 1994 한국비파괴검사학회지 Vol.14 No.2

일반적으로 회전기기의 저어널 베어링 부분은 윤활유 공급의 부족이나 윤활층에 이물질이 혼입되면 시스템의 고장이나 가동중단 등의 원인이 되기도 한다. 따라서 베어링 손상에 기인하는 사고와 관련된 안전운전 문제와 유지비용의 절감을 위해 여러가지 파괴 및 비파괴시험법들이 사용되어 왔다. 본 연구에서는 저어널 베어링에서 가장 발생하기 쉬운 윤활층에의 이물질이 혼입에 의해 야기되는 베어링 파손의 조기검출을 위해 음향방출 기술을 적용하였으며, 전보의 연구에 이어 좀더 정량적이고 체계적인 실험을 수행하였다. 실험실용으로 직접 제작한 모의베어링 시스템을 이용하여 여러 형태의 인위적인 이물질 흔입 상태를 만들어 실험하였으며 베어링 손상 및 결함 형태의 해석을 위해 AE rms level, 파형분석, AE 변수 등의 여러 파라메터를 사용하여 분석 고찰하였다. 그 결과 AE rms level의 변화가 이물질 흔입의 영향에 민감함을 보여주었으며 AE변수등 다른 정보들로부터 손상 원일별로 신호형태를 확인할 수 있었다. Journal bearings in the rotating machineries are vulnerable to the contamination or the insufficient supply of lubricating oil, which is likely to be the cause of unexpected shutdown or malfunction of these systems. Various destructive and nondestructive testing methods had been used for the reduction of maintenance cost and the operational safety problems due to the accidents related to bearing damages. In this experimental approach, acoustic emission monitoring in employed to the detection of incipient failure caused by intervention of foreign particles most probable in the journal bearing systems. Experimental schedules for the intervention of foreign particles was composed to be more quantitative and systematic than last study in consideration of minimum oil film thickness and particle size . The experiment was conducted under such designed conditions as inserting alumina particles to the lubrication layer in the simulated journal bearing system. Several parameters such as AE rms level, waveform, AE energy distribution and other AE event parameter are used for analysis and characterization of damage source. The results showed that the history of damage was well correlated with the changes of AE rms level and the types of damage source signal can be verified using other informations such an waveform, distribution of AE parameter etc.

마이크로 그루브 가공의 특성 평가

권동희,박진효,김정석,김병민,정융호,강명창 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

As demands for micro parts are on the increase in recent industries such as aerospace, biomedical, electronics, environment, information technology and display, the need for manufacturing such parts is also increasing. Major methods of manufacturing micro parts are based on semiconductor process technology such as lithography and etching and non-traditional machining using lasers, ultrasonic, ion-beams or electrical discharge. However, these methods require lots of time, workpiece materials are limited, and such methods are only applicable to the machining of two-dimensional shapes. Therefore, mechanical machining methods are required for the manufacturing of micro parts with complex shapes. This paper presents an investigation on the characteristics for micro groove machining by using the ultrahigh-speed air turbine spindle, and verifies the properties of mechanical method in fabricating molds for micro barrier ribs. As a result, the optimal machining condition could be found from the investigation of surface roughness according to the kinds of burr shapes in the fabricating of iron mold by using micro endmill.