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      • KCI등재

        붕장어 부산물로 제조한 붕장어탕의 식품학적 특성

        허민수(Min Soo Heu),이택상(Take Sang Lee),김혜숙(Hye-Suk Kim),지성준(Seung Joon Jee),이재형(Jae Hyoung Lee),김형준(Hyung Jun Kim),윤민석(Min Seok Yoon),박신호(Shin Ho Park),김진수(Jin-Soo Kim) 한국식품영양과학회 2008 한국식품영양과학회지 Vol.37 No.4

        붕장어 가공부산물인 머리와 frame를 효율적으로 이용하기 위한 일련의 연구로 붕장어 부산물을 이용한 붕장어탕의 개발을 시도하였고, 아울러 이의 식품성분 특성에 대하여도 살펴보았다. 살균조건 및 가온일수에 따른 붕장어탕의 저장성 부여를 위한 최적 살균조건은 F? value=8분으로 판단되었다. 붕장어탕의 일반성분은 수분의 경우 90.7%, 조단백질의 경우 4.8%, 조지방의 경우 2.6%, 조회분의 경우 1.5%를 나타내었다. 붕장어탕의 엑스분 질소 함량은 243.1 ㎎/100 g으로 시판 추어탕의 208.0 ㎎/100 g보다 높았다. 붕장어탕의 총 아미노산 함량은 4,310 ㎎/100 g이었고, 주요 구성아미노산은 glutamic acid(637.3 ㎎/100 g, 14.8%), glycine(409.1 ㎎/100 g, 9.5%) 및 alanine(404.4 ㎎/100 g, 9.3%)등이었다. 붕장어탕은 관능적인 비린내는 거의 감지되지 않았고, 맛은 우수하였으며, 항산화능이 인정되었으나 ACE 저해능은 크게 기대할 수 없었다. For the effective use of the conger eel by-products, such as head and frame, Tang, which is the Korean-type soup, from conger eel by-products (TCEB) was developed and its food component characterization was compared with that of commercial Chueotang, loach Tang. According to the results of viable cells and coliform group of TCEB heated at 115oC for various times, the reasonable F0 value was 8 min. The proximate composition of TCEB was 90.7% for the moisture, 4.8% for the protein, 2.6% for the lipid, and 1.5% for the ash. The extractive-nitrogen content of TCEB was 243.1 ㎎/100 g, which was higher than that of commercial Chueotang, 208.0 ㎎/100 g. The total amino acid content of TCEB was 4,310 ㎎/100 g and its major amino acids were glutamic acid (637.3 ㎎/100 g, 14.8%), glycine (409.1 ㎎/100 g, 9.5%) and alanine (404.4 ㎎/100 g, 9.3%). TCEB was not felt in the sensual fish odor and its sensual taste was good. The health functional properties for health of TCEB were 1.29 as a PF (protection factor) for antioxidative activity and 39.4% for angiotensin Ⅰ converting enzyme (ACE) inhibiting activity.

      • SCISCIESCOPUS

        Effect of spark plasma sintering conditions on the thermoelectric properties of (Bi<sub>0.25</sub>Sb<sub>0.75</sub>)<sub>2</sub>Te<sub>3</sub> alloys

        Lim, Sang-Soon,Kim, Ju-Heon,Kwon, Beomjin,Kim, Seong Keun,Park, Hyung-Ho,Lee, Ki-Suk,Baik, Jeong Min,Choi, Won Jun,Kim, Dong-Ik,Hyun, Dow-Bin,Kim, Jin-Sang,Baek, Seung-Hyub Elsevier 2016 JOURNAL OF ALLOYS AND COMPOUNDS Vol.678 No.-

        <P><B>Abstract</B></P> <P>As a field-assisted technique, spark plasma sintering (SPS) enables densification of specimens in a very short period of time compared to other sintering techniques. For high performance thermoelectric material synthesis, SPS is widely used to fabricate nanograin-structured thermoelectric materials by rapidly densifying the nanopowders suppressing grain growth. However, the microstructural evolution behavior of thermoelectric materials by SPS, another important process during sintering, has been rarely studied. Here, we explore SPS as a tool to control the microstructure by long-time SPS. Using p-type (Bi<SUB>0.25</SUB>Sb<SUB>0.75</SUB>)<SUB>2</SUB>Te<SUB>3</SUB> thermoelectric materials as a model system, we systematically vary SPS temperature and time to understand the correlations between SPS conditions, microstructural evolution, and the thermoelectric properties. Our results show that the relatively low eutectic temperature (∼420 °C) and the existence of volatile tellurium (Te) are critical factors to determine both microstructure and thermoelectric property. In the liquid-phase sintering regime, rapid evaporation of Te leads to a strong dependence of thermoelectric property on SPS time. On the other hand, in the solid-phase sintering regime, there is a weak dependence on SPS time. The optimum thermoelectric figure-of-merit (Z) of 2.93 × 10<SUP>−3</SUP>/K is achieved by SPS at 500 °C for 30 min. Our results will provide an insight on the optimization of SPS conditions for materials containing volatile elements with low eutectic temperature.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Spark plasma sintering (SPS) is used to synthesize the thermoelectric (Bi<SUB>0.25</SUB>Sb<SUB>0.75</SUB>)<SUB>2</SUB>Te<SUB>3</SUB>. </LI> <LI> Liquid phase and volatile element are a key for the microstructure and thermoelectric property. </LI> <LI> Thermoelectric figure-of-merit of 2.9 × 10<SUP>−3</SUP>/K is achieved at 500 °C for 30 min. </LI> </UL> </P>

      • KCI등재

        Influence of Al2O3 Content and Cooling Rate on Crystallization in Fe2O3–CaO–SiO2–Al2O3 Systems

        Tae Jun Park,Joon Sung Choi,Dong Joon Min 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

        The behavior of silico-ferrite of calcium and aluminum (SFCA) phases and the influence of sintered ore quality were investigatedusing a confocal laser scanning microscope to understand how the Al2O3content of iron ore affects the sintered orestructure and the crystallization behavior of SFCA in a Fe2O3–CaO–Al2O3–SiO2 pseudo-quaternary system. The experimentalresults were used to inform simulations of the heterogeneous dynamic behavior in response to the rapid temperature changesand various chemical compositions typically encountered in actual sintering processes. Increasing the Al2O3content in theFe2O3–CaO–Al2O3–SiO2 pseudo-quaternary system led to the hematite content decreasing, which affects the reducibilityof the sintered ore. The correlation between the creation of SFCA and the cooling effect associated with varying the Al2O3is discussed in detail.

      • KCI등재

        다양한 냉동 및 해동공정 조합이 표고버섯의 품질에 미치는 영향

        심준보 ( Jun Bo Shim ),조연지 ( Yeon Ji Jo ),최미정 ( Mi Jung Choi ),민상기 ( Sang Gi Min ),유선미 ( Seon Mi Yoo ),천지연 ( Ji Yeon Chun ) 한국산업식품공학회 2015 산업 식품공학 Vol.19 No.3

        본 연구는 다양한 냉동방법(강제송풍식냉동, 극저온냉동, 일반냉동)과 해동방법(자연해동, 유수해동, 초음파해동, 전자레인지해동)을 조합하여 처리했을 때 표고버섯의 물리적 품질에 미치는 영향을 관찰하고, 표고버섯의 품질을 유지하는 가장 효과적인 냉·해동 공정을 탐색하는 것이 목적이었다. 급속냉동법(강제송풍식냉동, 극저온냉동)으로 처리한 경우 표고버섯의 해동감량, 보수력, 수분함량은 큰 변화 없이 품질을 유지 하는데 효과적인 것으로 관찰되었다. 특히 보수력은 저속냉동(일반냉동) 및 저속해동(자연해동) 처리의 유무가 영향을 미치는 것으로 나타났다. 전단력의 경우 냉동방법에 의한 영향보다, 전처리 및 해동방법에 더 영향을 받는 것을 판단된다. pH 및 색도는 냉동방법 및 해동방법에 따라 거의 차이가 없는 것으로 관찰되었다. 표고버섯의 물리적 특성을 효과적으로 유지 할 수 있는 처리 조합은 급속냉동(극저온냉동) 및 급속해동(유수해동, 초음파해동, 전자레인지해동)을 한 경우이며, 또한 유지하고 하는 물리적 특성에 따라 냉동 및 해동방법을 다양하게 조합하여 처리한다면, 식품의 품질을 보존하는데 더욱 효과적일 것으로 사료된다. In this study, the potential of various freezing and thawing combinations was investigated for frozen storage of mushroom (Lentinula edodes). Lentinula edodes were sliced (5×5×50 mm) and then blanched in boiling water for 1 min. Samples were frozen by either natural air convection freezing (NCF, -24℃), air-blast freezing (ABF, -45℃), or liquid nitrogen freezing (LNF, -100℃). Frozen Lentinula edodes were thawed to a central temperature of 4℃ using either flowing water thawing (FT, 10℃), microwave thawing (MT, 400 W), sonication thawing (ST, 40 kHz, 10℃), or natural air convection thawing (NT, 20±5℃). In LNF Lentinula edodes, MT showed the most rapid thawing within 2.5 min followed by ST (30 min), FT (37 min), and NT (75 min). Quality attributes were evaluated by thawing loss, texture (hardness), water content, water holding capacity, pH, and color. A combination of LNF and MT induced the lowest thawing loss among tested combinations of each freezing and thawing. Thawing loss of frozen Lentinula edodes by LNF method was the lowest by MT. pH values NT of ABF method were significantly higher than blanched Lentinula edodes. In our study, MT minimized the quality changes of frozen Lentinula edodes when it was combined with ABF or LNF.

      • SCIESCOPUSKCI등재

        Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells

        ( Ji Yong Kim ),( Jai Sung Lee ),( Yong Seok Han ),( Jun Hee Lee ),( Inhyu Bae ),( Yeo Min Yoon ),( Sang Mo Kwon ),( Sang Hun Lee ) 한국응용약물학회 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.6

        Human mesenchymal stem cells (MSCs) have been used in cell-based therapy to promote revascularization after peripheral or myocardial ischemia. High levels of reactive oxygen species (ROS) are involved in the senescence and apoptosis of MSCs, causing defective neovascularization. Here, we examined the effect of the natural antioxidant lycopene on oxidative stress-induced apoptosis in MSCs. Although H2O2 (200 mM) increased intracellular ROS levels in human MSCs, lycopene (10 μmM) pretreatment suppressed H2O2-induced ROS generation and increased survival. H2O2-induced ROS increased the levels of phosphorylated p38 mitogen activated protein kinase (MAPK), Jun-N-terminal kinase (JNK), ataxia telangiectasia mutated (ATM), and p53, which were inhibited by lycopene pretreatment. Furthermore, lycopene pretreatment decreased the expression of cleaved poly (ADP ribose) polymerase-1 (PARP-1) and caspase-3 and increased the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax), which were induced by H2O2 treatment. Moreover, lycopene significantly increased manganese superoxide dismutase (MnSOD) expression and decreased cellular ROS levels via the PI3K-Akt pathway. Our findings show that lycopene pretreatment prevents ischemic injury by suppressing apoptosis-associated signal pathway and enhancing anti-oxidant protein, suggesting that lycopene could be developed as a beneficial broad-spectrum agent for the successful MSC transplantation in ischemic diseases.

      • 습식텍스쳐를 이용한 단결정 실리콘 광학적 · 전기적 특성 연구

        한규민(Han Kyu-min),유진수(Yoo Jin-su),유권종(Yoo Kwon-jong),이희덕(Lee Hi-deok),최성진(Choi Sung-jin),권준영(Kwon Jun-young),이준신(Yi Jun-sin) 한국태양에너지학회 2010 한국태양에너지학회 학술대회논문집 Vol.2010 No.4

        The presence of ultrasonic wave in caustic cleaning process enhances the remove pollutants, and more homogeneous, textured structure. The silicon wafers, cleaning in Deconex OF 145 solution (0.5~2wt %) with DIW under ultrasonic environment for 5 min. The presence of uniform thin layer of SiO2 on c-Si surface enhances etching rate in the caustic etching mixture solution of NaOH (1.5 wt %), DI water and IPA (6 wt %) at 90℃ for 20 min and results in a fine, more homogeneous and small textured structure.

      • KCI등재

        Effects of Regular Exercise and L-Arginine Intake on Abdominal Fat, GH/IGF-1 Axis, and Circulating Inflammatory Markers in the High Fat Diet-Induced Obese Aged Rat

        Sok Park(박석),Ki Woon Sung(성기운),Jin Lee(이진),Cheon Ho Lee(이천호),Young Jun Lee(이영준),Young June Yoo(유영준),Kyoung Shil Park(박경실),Byung Jin Min(민병진),Yong Sub Shin(신용업),Jung Suk Kim(김정석),Hun Jung(정훈) 한국생명과학회 2012 생명과학회지 Vol.22 No.4

        본 연구는 비만과 노화가 동시에 유발된 흰쥐에서 12주간의 트레드밀 운동과 L-arginine의 투여가 복부지방량, GH, IGF-Ⅰ, somatostatin, fibrinogen, PAI-1에 미치는 영향을 관찰하고 이를 개선하는데 더욱 효과적인 방법을 제시하는데 그 목적이 있다. 이를 위해 단독 처치 군과 복합 처치 군으로 나누어 실험하여 그 효과를 비교, 분석한 결과 다음과 같은 결론을 얻었다. 1. 복부지방량은 통제집단에 비해 모든 집단에서 유의하게 감소하였다(p<0.01). 2. AG+EX, AG+LA+EX집단에서 통제집단에 비해 GH의 혈중 농도가 유의하게 높게 나타났다(p<0.1). 3. AG+EX, AG+LA+EX집단에서 통제집단에 비해 IGF-Ⅰ의 혈중 농도가 유의하게 증가하였다(p<0.01). The purpose of this study was to investigate the effect of exercise and/or L-arginine on abdominal fat, IGF-1 on GH/IGF-1 axis, fibrinogen, and PAI-1 in aged and obese rats. Male Sprague-Dawley rats were treated with a D-galactose aging inducing agent (50 mg/kg) given intraperitoneally for 12 weeks. Thirty-two male Sprague-Dawley rats were treated and divided into four groups: aging-high fat diet group (AG+HF), AG+HF with L-arginine intake group (AG+LA), AG+HF with exercise group (AG+EX), and AG+EX with L-arginine intake group (AG+LA+EX). The experimental rats underwent treadmill training (60 min/day, 6 days/week at 0% gradient) for 12 weeks. L-arginine was given orally (150 mg/kg/day) for 12 weeks. After the experiment, blood was collected from the left ventricle and abdominal fat was extracted. The results showed that GH was significantly increased in AG+EX and AG+AL+EX. IGF-1 was significantly increased in both the AG+AL+EX and AG+EX group (p<0.05), while fibrinogen and PAI-1 were not significantly different among the groups. Abdominal fat was significantly decreased in the AG+LA, AG+EX, and AG+LA+EX groups (p<0.05) compared with the AG+HF group. In conclusion, this study suggests that exercise alone or L-arginine alone or a combination not only increases the GH and IGF-1 concentration, but also decreases the abdominal fat mass.

      • Totally Laparoscopic Pancreaticoduodenectomy Using 3D Flexible Laparoscopic System

        ( Heon Tak Ha ),( Ja Ryung Han ),( Hyung Jun Kwon ),( Jae Min Chun ),( Sang-geol Kim ),( Yoon Jin Hwang ),( Young Seok Han ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: Robotic PD has not yet been expanded due to the needs of the dedicated teams and the excessive costs. 3D flexible laparoscopic system (3D) with depth perception and spatial orientation allows the precise dissection of the dangerous site and facilitate the comfortable reconstruction. We present experiences regarding the efficacy of L-PD using 3D. Methods: Totally L-PD was attempted in 15 patients from June 2016 to June 2017. However, conversion to open PD was required in one patient with tumor invasion to the superior mesenteric vein. Pancreaticojejunostomy was completed with the dunking procedure in 1 patient and with duct-to-mucosa technique in 13 patients. Results: Mean operation time was 500 min. The replaced right hepatic artery originated from superior mesenteric artery of hepatic artery was identified in one patient and preserved well because of the precise dissection under the excellent visual field. The mean size of pancreatic duct and hepatic duct were 3 mm and 10 mm. There was no major intra-operative complications and post-operative mortality. Postoperative complications were detected in 7 patients, including pancreatic fistula (n=5), and delayed gastric emptying (n=2). All pancreatic fistula was grade A and were recovered with conservative treatment. Conclusions: In selected patients, L-PD is a safe and effective procedure with comparable surgical outcomes to open surgery. Especially, we believe that 3D will play an important role in the expansion of complicated PD surgery and will provide a bridge role for future robot systems.

      • SCIESCOPUSKCI등재

        Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells

        Kim, Ji Yong,Lee, Jai-Sung,Han, Yong-Seok,Lee, Jun Hee,Bae, Inhyu,Yoon, Yeo Min,Kwon, Sang Mo,Lee, Sang Hun The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.6

        Human mesenchymal stem cells (MSCs) have been used in cell-based therapy to promote revascularization after peripheral or myocardial ischemia. High levels of reactive oxygen species (ROS) are involved in the senescence and apoptosis of MSCs, causing defective neovascularization. Here, we examined the effect of the natural antioxidant lycopene on oxidative stress-induced apoptosis in MSCs. Although $H_2O_2$ ($200{\mu}M$) increased intracellular ROS levels in human MSCs, lycopene ($10{\mu}M$) pretreatment suppressed $H_2O_2$-induced ROS generation and increased survival. $H_2O_2$-induced ROS increased the levels of phosphorylated p38 mitogen activated protein kinase (MAPK), Jun-N-terminal kinase (JNK), ataxia telangiectasia mutated (ATM), and p53, which were inhibited by lycopene pretreatment. Furthermore, lycopene pretreatment decreased the expression of cleaved poly (ADP ribose) polymerase-1 (PARP-1) and caspase-3 and increased the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax), which were induced by $H_2O_2$ treatment. Moreover, lycopene significantly increased manganese superoxide dismutase (MnSOD) expression and decreased cellular ROS levels via the PI3K-Akt pathway. Our findings show that lycopene pretreatment prevents ischemic injury by suppressing apoptosis-associated signal pathway and enhancing anti-oxidant protein, suggesting that lycopene could be developed as a beneficial broad-spectrum agent for the successful MSC transplantation in ischemic diseases.

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