Cell Separation: Ethanol‐Dispersed Polymer Nanofibers as a Highly Selective Cell Isolation and Release Platform for CD4⁺ T Lymphocytes (Adv. Funct. Mater. 21/2012)

Jun, Seung‐,Hyun,Kim, Kwanghee,An, Hyo Jin,Kim, Byoung Chan,Sonn, Chung Hee,Kim, Miju,Doh, Junsang,Yee, Cassian,Lee, Kyung‐,Mi,Kim, Jungbae WILEY‐VCH Verlag 2012 Advanced functional materials Vol.22 No.21

<P>Electrospun and alcohol‐dispersed polystyrene‐poly(styreneco‐maleic anhydride) (PS‐PSMA) nanofibers, which allow for facile conjugation of antibodies, are used as an innovative cell isolation/enrichment and support/release platform. As reported by Kyung‐Mi Lee, Jungbae Kim, and co‐workers on page 4448, this work opens up the potential for an innovative immune cell therapy in which specific immune cells are isolated by antibody‐conjugated nanofibers and are directly delivered to the target sites under the controlled and sustained release of immune cells via in vivo activation. </P>

Phase Transformation Modeling for Hypo Peritectic Steel in Continuous Cooling

Jun‑hyun Jo,Kyung‑woo Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.7

Phase change of steel during cooling affects the slab qualities in continuous casting. Especially, crack susceptibility of hypoperitectic steel is high because large volume shrinkage occurs by peritectic phase transformation during solidification andcooling. In continuous cooling, phase change is different from the behaviors under the equilibrium condition, such as undercoolingand extend of peritectic reaction, etc. Therefore, we develop a new phase change model considering thermodynamics,empirical equations, and carbon diffusion in each phase to predict phase change behavior during continuous cooling. Inthis model, phase change of hypo peritectic steel comprises 5 stages until all phases become the γ phase. The velocities ofthe δ/γ interface and phase fractions during cooling are calculated according to cooling rate, undercooling of the γ phase,and carbon contents. The results show that if solidification ends by the δ phase during dTp,the γ phase is formed by massivetransformation. On the contrary, if peritectic reaction starts with liquid, the γ phase is formed and grows by diffusionaltransformation. In latter case, massive transformation of remaining δ phase can occur with high undercooling or very fastcooling rates. This analysis shows that there are several different paths depending on carbon contents of hypo peritectic steels.

Numerical Analysis on Crack Generation Behavior of Hypo Peritectic Steel in Continuous Casting Process

Jun‑hyun Jo,Min‑seok Park,Kyung‑woo Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.11

Hypo peritectic steels exhibit a high possibility of longitudinal crack during continuous casting. Therefore, many researchershave studied the mechanisms of crack generation in hypo peritectic steel. Stress in solidified shell, or volume contractionwith small liquid fractions were suggested as the mechanisms of crack generation. A new model was developed for predictingpossibility of crack generation by calculating strain rates in solid, volume contraction rate during solidification, and theprobability of liquid unfilling in continuous cooling processes. The results show that massive transformation from the δphase to the γ phase, and peritectic transformation during solidification can be the main crack generation mechanisms. Furthermore,a linear relationship exists between the amount of undercooling for peritectic transformation (dTp) and the carboncontent of the boundary for dividing the two crack generation mechanisms. Additionally, the longitudinal crack ratios ofthe field results are analyzed through strain rates in solid and liquid unfilling possibilities. Relative positions in the range ofhypo peritectic steel and effective carbon contents are suggested to analyze the crack ratio of steels with alloying elements. This analysis shows that the results obtained from the new models for crack generation possibility are usable, and dTpcangenerate the behavioral differences in crack generation according to the conditions.

경희대학교 서울캠퍼스 진입로 및 주변 보행공간 기본계획

김동찬,김영준,마원,김충희,노경식,이가영 경희대학교 부설 디자인연구원 2008 예술· 디자인학연구 Vol.11 No.1

Kyung-Hee University in Seoul accept changing of education environment to deal with World's information technology society so that school had preparing the Masterplan to grow up campus's vision since 2006th. Finally we finish up this plan. However, realization of the Masterplan need a lot of financial resources, much times and phases in improvement. Especially, our school needs symbolized business in 2009 due to school of 60th anniversary. So we made a plan that to construct by design which is going to reshape campus's main road and westside afforest place for future. As a result, purpose of research is to improve an atmosphere conducive to academic pursuit, to show up greatness of school and to deal with changing school's environment rapidlly. That is why the Masterplan is trying to find school of superb scenic and developing of environment to congratulate of our school's 60th anniversary main approach and walking spaces.

경희대학교 국제캠퍼스 걷고 싶은 거리 조성계획

김동찬,김영준,마원,김충희,노경식,이가영 경희대학교 부설 디자인연구원 2008 예술· 디자인학연구 Vol.11 No.1

Kyung-Hee University Global Campus accepted changing of education environment to adapt to the World's information technology society so that school has been preparing the Master plan to grow up campus's vision since 2007. However, realization of the Master plan need a lot of financial resources, much times and phases in improvement. Especially, our university needs symbolized business in 2009 due to the 60th anniversary of our university. Based on this we want to improve the main entrance road environment from school gate to the school of international management and reconstruct the spatial environment beside the main road. The purpose of this research is to construct a pedestrian space environment and reconstruct the campus environment which adapt to the new times' demands. That is why the Master plan is trying to find the landscape scenic which adapts to our school' s main entrance space and the improvement method about the pedestrian space of the Global campus to congratulate of our university's 60th anniversary.

DNA 포렌식에 의한 DNA 증거의 증거능력에 관한 고찰

김동준(Kim, Dong­Jun),오경식(Oh, Kyung­Sik) 한국피해자학회 2018 被害者學硏究 Vol.26 No.1

Advances in forensic DNA analysis have led to tremendous improvements in identifying and confirming perpetrators and victims. This has added credibility to DNA evidence, resulting in cases where criminals are more likely to be forced to own up to their criminality and culpability. This paper addresses scientific and technical theories the DNA analytical technologies are founded on as well as the suitability of individual analytical procedures. Beyond these issues, it went on to discuss the requirements that need to be met in order for DNA evidence, collected through forensic DNA testing, to be admissible in court in Korea. DNA testing results are presented in court in the form of certified expert testimony. And according to Article 313, “Statement, etc.” of the Criminal Procedure Act, as long as the DNA evidence offered is free from errors in laboratory procedures and concluding interpretations of the person responsible for producing the expert opinion recording, such procedures and outcomes will be admissible as legitimate evidence in court. In other words, the aforementioned expert testimony is nothing short of legislative intent at acknowledging the testimony as admissible in court, thus should not be understood as standards with which the scientific evidence concerned is admissible and tried at court. For this reason, admissibility in court of DNA evidence from DNA forensic analysis should not only be based on whether it meets the requirements as expert testimony, but also whether its theories of reasoning and analyses are founded on acceptable scientific principles. Furthermore, the tools and methods used in DNAprofiling need to be validated, allowing the analyzed result in question to be assessed for admissibility in criminal court. Trends of precedents regarding DNA evidence seem to require that the relevancy of DNA analytical theories, suitability of DNA analytical methods that have implemented these theories, and maintenance of the chain of custody of evidence by applying scientific procedures to the targets concerned, be met for the evidence to be admissible in court. Furthermore, it may be fair to say that within the structure of Korea’s criminal prosecution, the processes involved in determining whether or not DNA evidence is credible may be part of what is needed to assess its probative value. At the moment, theoretical foundations of DNA analysis are deemed reliable with the overall approval of scientific circles, however there are improvements made all the time in standard analytical methodologies and procedures regarding their implementation and analytical techniques. This has created an unbridgeable gap between common knowledge and the outcomes of scientific research activities that legal experts, particularly trial judges, are left with no choice but to be more and more dependent on expert testimony when they assess the credibility of DNA evidence. Still, the more weight DNA analysis carries, the more likely serious errors in laboratory testing occur; thus, there is increased emphasis on how to keep the chain of custody in determining the admissibility of DNA evidence, for example, the qualification of those involved in testing, sample collection and preservation, stability of the testing methods that have been utilized, and conformance to analytical procedures. Therefore, if there is evidence that is crucial in determining guilt in crime, and the continuity of its preservation is closely related to the presence and integrity of the evidence concerned, namely DNA evidence, the defendant should be afforded the opportunity for the credibility of evidence to be tried in court during the entire processes of such evidence being collected, stored and analyzed to: prevent wrongful accusations; to make court proceedings more impartial; and to comply with appropriate procedures. To this end, cross examination of witnesses, disclosure of extensive evidence of the parties involved, and cross examinat

기억의 정치와스토리텔링 근현대 역사에 대한 기억의 보전과 공유 -부산근대역사관 운영 사례를 중심으로-

장경준 ( Kyung Jun Jang ) 대구사학회 2012 대구사학 Vol.106 No.-

Conservation and Share of Memory on Modern History -Focused on Operating Case of the Busan Modern History Museum- Jang, Kyung-jun [Abstract] In this writing, after retrospecting activities of the Busan Modern History Museum on memory conservation during the time and investigating outcomes and problems appearing there, it suggested tasks to share memory on the public and modern history. The Busan Modern History Museum, from 2003 opening to now, through exhibit, acamedic research and investigation, social education, and etc, has thrown its effort to introduce history and culture of modern Busan. In the result, the existence of the Busan Modern History Museum gradually became known and the status as modern specialized museum increased. However, there are still many remaining tasks in front of the Busan Modern History Museum. First, contents fitting to the place should be contained so that historical sites are revived as places of memory. Second, through exhibits and education, it should communicate with the public and local communities endlessly. Regarding museum and exhibition, exhibit and education are main channel and method to communicate with them. Thus, afterwards more materials should be collect and studied, and organized and preserved, containing stories here to convey. Third, through endless self-examination and efforts, the public`s support and cooperation should be drawn. Without their support and cooperation, playing its role as the place of memory is impossible from the start. For this, it should commit itself to its duty such as collecting materials and conservation, investigation research, exhibit, education, and etc, and local governments and etc should help this from the side with the extensive support. At the same time, local communities along with colleges should spare no active support and advice with higher attention at museum and exhibition. By doing this, modern museums and exhibition will settle down as the place of memory to share and communicate the real memories of the public and history.

척추질환 입원환자의 연도별 변동추이에 대한 통계적 고찰

박경수 ( Kyung Su Park ),이준환 ( Jun Hwan Lee ),정석희 ( Seok Hee Chung ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.4

Objectives : The aim of this study was to find the change in the number of inpatient with spine disease, data were reviewed on inpatients who was diagnosed as spine disease in the Kyung-hee Medical Center(KHMC) for 25 years(1980~2004). Methods : Analysis data of the number of spinal disease was based on the KHMC annual report for 25 years(1980~2004). Results : 1. The number of inpatient in KHMC with spine disease has been increasing during 25years from 1980 to 2004(p-value:0.000) 2. The number of inpatient in KHMC with ankylosing spodylitis(AS) is increasing during 25years from 1980 to 2004(p-value=0.000) 3. The number of inpatient in KHMC with spinal stenosis is increasing during 25years from 1980 to 2004(p-value=0.000) 4. The number of inpatient in KHMC with herniated nucleus pulposus of cervical spine(HNP of C-spine) is increasing during 25years from 1980 to 2004(p-value=0.000) 5. The number of inpatient in KHMC with herniated nucleus pulposus of Lumbar spine(HNP of L-spine) is increasing during 25years from 1980 to 2004 (p-value=0.007) Conclusions : It is suggesting that the number of patients of spinal stenosis and HNP of L-spine increase at KHMC.

The effect of neuropeptides on secretion of Interleukin-8(IL-8)

Kim, Kyung-Jun,Park, Sang-Hyuk,Choi, Kyoung-Kyu,Park, Sang-Jin 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.3

본 연구는 치수조직, 치은, 치주인대로부터 배양된 조직을 SP (Substance P)로 4시간, SP, CGRP (Calcitonin Gene-related Peptide), Tumor necrosis factor-α (TNF-α)로 8시간 자극 후 RNase Protection Assay를 시행하고, IL-8의 분비량을 측정해 다음 결과를 얻었다. 1. IL-8 mRNA는 모든세포에서 발현됐다. 2. IL-8 mRNA 발현은 SP (10^(-5)M)와 SP (10^(-8)M)로 4시간 자극 시 증가되지 않았다. 3. IL-8 mRNA 발현은 SP (10^(-4)M)와 CGRP (10^(-6)M)로 8시간 자극 시 증가되지 않았다. 4. TNF-α (2 ng/㎖) 자극 시, IL-8 mRNA 발현이 증가됐다. 5. 치은 세포를 CGRP (10^(-6)M)로 8시간 자극 시, IL-8 분비량이 증가했다 (p < 0.05). 6. 치주인대 세포를 SP (10^(-4)M)로 8시간 자극 시 IL-8 분비량이 증가했다 (p < 0.05). We investigated the secretion of Interleukin-8 (IL-8) from ginviva and periodontal ligament stimulated with Substance P (SP) and Calcitonin Gene-related Peptide (CGRP). Gingiva (GF), periodontal ligament (PDLF) and pulp (PF) tissues were collected from extracted instact 3rd molars. Cultured cells were stimulated with different concentrations of SP for 4 hrs, and stimulated with SP, CGRP and Tumor Necrosis Factor-α (TNF-α) for 8 hrs. Then RNase Protection Assay was carried out. ELISA was performed using supernatants of stimulated cells for quantitative analysis of IL-8. Results were assessed using supernatants of stimulated cells for quantitative analysis of IL-8. Results were assessed using student t-test with significance of P < 0.05. According to this study, the results were as follows: 1. IL-8 mRNA was detected in all type of cells studied (PF, GF and PDLF). 2. IL-8 mRNA expression was not increased after stimulating 4 hrs with SP (10^(-5)M) and SP (10^(-8)M) compared with Mock stimulation in all type of cells studied. 3. IL-8 mRNA expression was not increased after stimulating 8 hrs with SP (10^(-4)M) and CGRP (10^(-6)M) compared with Mock stimulation in all type of cells studied. 4. TNF-α (2 ng/㎖) increased the expression of IL-8 mRNA in all kind of cells studied. 5. The secretion of IL-8 from GF was increased 8 hrs after the stimulation with CGRP (10^(-6)M) (p < 0.05). 6. The secretion of IL-8 from PDLF was increased 8 hrs after the stimulation with SP (10^(-4)M) (p < 0.05). Calcitonin Gene-related Peptide (CGRP) increased Interleukin-8 (IL-8) which plays an important role in chemotaxis of neutrophil in Calcitonin Gene-related Peptide (CGRP) gingival tissue, whereas Substance P increased the secretion of IL-8 from periodontal ligament.

‘쓰이는 텍스트’로서의 『별건곤』과 대중문학 독자의 형성

전은경(Jun, Eun-kyung) 한국어문학회 2014 語文學 Vol.0 No.125

This paper aims to investigate the Magazine Byulgungon as “a Scriptible Text” and the formation of readers for Popular literatures. Especially readers in the Magazine Byulgungon were connected to new popular literature in 1930’s. The Magazine Byulgungon was published in Oct. 1926, and has been discontinued as Vol. 73. in Jun. 1934. At the first place, it was very first magazine for “tastes” in colonized Chosun. Tastes were related with readers’s who were the people of the middle classes or the lower classes. Actually editors in the Magazine Byulgungon would like to educate readers of the middle or low classes, reading the practical contents in the magazine. However, readers’ desires were different from intellectual editors and authors. They had desired to change the Magazine Byulgungon owing to regard it as “a Scritible Text” by Roland Gerard Barthes. According to The Reader, the Text, the Poem written by Louis M. Rosenblatt, editors’ desires and readers’ had caused “the transaction” with each other in the Magazine Byulgungon. Therefore the Magazine Byulgungon is very important text as “a Scriptible Text” that readers and editors continuously created it together. This transaction has led to several popular narratives and modern popular readers. At the same time, the Magazine Byulgungon had made popular readers prepare be able to be reders for modern literatures.