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Abbreviated chemotherapy for limited-stage diffuse large B-cell lymphoma after complete resection
조정민,윤덕현,이상욱,박찬식,Jooryung Huh,Kyoungmin Lee,강은희,Shin Kim,서철원 대한혈액학회 2014 Blood Research Vol.49 No.2
Background Abbreviated chemotherapy followed by radiotherapy or full cycles of chemotherapy is recommended as a standard treatment for limited-stage (LS) diffuse large B-cell lymphoma (DLBCL). After complete resection of tumors, however, Burkitt and childhood B-cell Non-Hodgkin lymphoma show favorable outcomes, even after abbreviated chemotherapy of only 2 or 3 cycles. We investigated the effectiveness of abbreviated chemotherapy in patients with LS DLBCL after complete tumor resection. Methods We retrospectively reviewed 18 patients with LS DLBCL who underwent complete tumor resection followed by either 3 or 4 cycles of chemotherapy between March 2002 and May 2010. Results With a median follow-up period of 57.9 months (range, 31.8‒130.2 months), no patients experienced disease relapse or progression; however, 1 patient experienced secondary acute myeloid leukemia during follow-up. The 5-year progression-free survival rate and overall survival rate were 93.3% and 94.1%, respectively. Conclusion These results warrant further investigation into abbreviated chemotherapy as an alternative treatment for patients who have undergone complete resection of LS DLBCL.
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Detection of Epstein - Barr Virus Encoded RNA in Cutaneous T - cell Lymphoproliferative Disorders
Chang, Sung Eun,Huh, Jooryung,Choi, Jee Ho,Sung, Kyung Jeh,Moon, Kee Chan,Koh, Jai Kyoung,Yoon, Ghil Suk 대한피부과학회 2000 Annals of Dermatology Vol.12 No.3
Background: Recent reports suggest that Epstein-Barr virus (EBV) may play an important role in such a wide spectrum of human neoplasia. Recently, peripheral T cell lymphomas and particularly, angiocentric lymphomas (ACL), increasingly are reported to be associated with EBV. Nasal-type and nasal T/NK cell lymphoma (TNKL) have recently been reported to comprise most of ACLs. The prognosis of these tumors has been extremely poor. Objective: The purpose of this study was to investigate EBV association in primary or secondary cutaneous T-cell lymphoproliferative disorders and to identify any prognostic association. Methods: Thirty six patients with primary or secondary cutaneous T-cell lymphoproliferative (CTCL) disorders were examined to evaluate the presence of Epstein-Barr virus using in situ hybridization for EBV-encoded RNA (EBER). Results : EBER was detected in tumor cells in one third of the total cases (13/36); 4/4 secondary skin lymphoma from nasal TNKL, 8/8 primary cutaneous nasal type TNKLs and 1/5 mycosis fungoides (MF). EBER was not detected in the following disease: 6 cases of anaplastic large cell lymphomas (ALCL) including 2 cases of probable NK-like T cell lineage, 3 lymphomatoid papulosis, 2 CD56(-) T cell ACLs and 7 subcutaneous panniculitic T-cell lymphomas (SPTL) by Revised European-American Lymphoma (REAL) classification and recent concept of further classification into NK-cell lineage. One case of T-cell pseudolymphoma as a negative control was also negative in EBER. Conclusion : High incidence of EBV was observed in primary or secondary CTCLs in Koreans, with predilection for nasal and nasal type TNKL. In MFs, an erythrodermic MF with fatal outcome was associated with EBV and the EBV detection might reflect worse prognosis in MFs as seen in an aggressive course of nasal and nasal type TNKLs.
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국내 진로교육학 연구동향(1993-2017): 초‧중‧고등학생을 중심으로
김도희(Kim Dohee),박주령(Park Jooryung) 학습자중심교과교육학회 2018 학습자중심교과교육연구 Vol.18 No.23
본 연구는 초 중 고등학생을 대상으로 한 국내 진로교육 연구의 동향을 살펴보고, 향후 발전 방향을 모색하는 데에 그 목적이 있다. 이를 위하여, 1993년부터 2017년 사이에 “진로교육연구”에 게재된 논문 649편을 검토한 후 연구목적에 맞게 초 중 고 등학생을 대상으로 한 224편의 논문을 선별하였으며, NetMiner 4.3 프로그램을 사용하여 텍스트 네트워크 분석을 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, 초등학생을 대상으로 한 논문에서 나타난 주요 텍스트는 진로에 대한 흥미와 포부, 학습, 자아개념, 성 역할, 부모양육 태도인 것으로 나타났다. 그리고 중학생을 대상으로 한 논문에서 나타난 주요 텍스트는 진로에 대한 정보탐색, 체험과 경험, 의사결정, 자아개념, 진로준비 행동인 것으로 나타났다. 한편, 고등학생을 대상으로 한 논문에서 나타난 주요 텍스트는 진로 결정, 진학과 취업준비 행동, 진로성숙, 정체감인 것으로 나타났다. 둘째, 고등학생을 대상으로 한 논문에서 추출된 텍스트의 네트워크 구조는 적절한 분화와 응집을 이루는 형태로 구성된 것으로 나타나 연구 분야가 체 계적으로 축적되고 있는 것으로 나타났다. 그러나 초등학생과 중학생을 대상으로 한 논문에서 추출된 텍스트의 경우에는 단일 네트워크의 형태로 나타나 연구 분야가 체계화되지 않은 것으로 나타났다. 이러한 결과를 바탕으로 향후 진로교육의 발전 방향과 시사점을 논의하였다. The purpose of this study is to examine the current status of korean career education research for elementary, middle, and high school students and to explore the development direction of career education field. The final 224 papers on elementary, middle, and high school students were selected to analysis from the 649 papers published in Career Education Research from 1993 to 2017. The researchers conducted a text network analysis using NetMiner 4.3 program. The results of this study are as follows. First, in the papers on elementary school students, the texts about career interest, aspiration, learning, self concept, gender role, and parenting attitude was mainly dealt with. And in the papers on middle school students, the texts about information search, experience and experience, decision making, self-concept, and career preparation behaviors were mainly dealt with. In the papers on high school students, the texts about career decision, career advancement, job preparation behavior, career maturity, and identity were mainly dealt with. Second, the network structure of the text extracted from the papers on high school students is composed of appropriate differentiation and cohesion, so that the research fields are accumulating systematically. However, in the case of elementary and middle school research literature, it has not been systemized in the form of a single network. Based on the results of this study, future directions and implications of career education were discussed.
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성인여성의 우울 수준에 따른 얼굴자극평가법(FSA) 반응 차이 연구
고은정(Ko, Eun-Jung),박주령( Park, Jooryung),이근매(Lee, Keun-Mae) 한국미술치료학회 2020 美術治療硏究 Vol.27 No.3
본 연구는 성인여성의 우울수준에 따라 얼굴자극평가법(FSA)의 자극그림 1과 2의 반응 차이를 검토하여 우울선별도구로 활용 가능성을 제시하는데 그 목적이 있다. 경기도에 거주하는 성인여성 200명으로 통합적 한국판 CES-D척도(우울증간이선별도구)를 실시한 후 얼굴자극평가법(FSA)을 실시하여 자료를 수집하였다. 우울 수준에 따라 우울집단 69명과 비우울집단 114명을 선별하여 얼굴자극평가법(FSA) 채점매뉴얼 2판 채점항목에 근거하여 교차분석을 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, Betts(2016)의 ‘FSA RATING MANUAL 2nd EDITION’의 평가 기준은 Cohen’s Kappa 상관계수에서 높은 수준의 신뢰도를 나타냈다. 둘째, 성인여성의 우울 수준에 따라 자극그림 1, 2의 ‘색칠 정도’, ‘색의 적절성’, ‘내적 에너지’, ‘논리성’, ‘발달단계’, ‘보속성’의 항목에서 유의미한 반응 차이가 나타났다. 우울 성인여성은 색을 칠하지 않고 선으로만 표현하거나 적절하지 않은 색을 사용하는 빈도가 많았다. 또한 낮은 수준의 내적 에너지를 나타내었고, 비논리적이거나 기괴한 요소가 있는 그림을 그리는 반응을 보였다. 끝으로 본 연구를 통한 연구의 시사점과 얼굴자극평가법(FSA)의 활용가능성을 제시하였다. The purpose of this study was to examine the applicability of Face Stimulus Assessment(FSA) as a supplementary indicator of the level of depression among adult women. The researchers recruited 200 adult women who volunteered to be tested using the Center for Epidemiologic Studies Depression Scale (CES-D) and the FSA. Of these, 69 depressed women and 114 non-depressed women were selected as participants, and cross-analysis was performed based on their scores on the second edition of the FSA. The results of the study are as follows. First, the significantly high level of the evaluation criteria of Bett’s (2016) Rating Manual (2nded.) was confirmed by an absolute inter-rater agreement based on Cohen’s Kappa Coefficient. Second, significant differences in the response characteristics of adult women who took the FSA were categorized by in categories of “Color Prominence,” “Color Fit,” “Implied Energy,” “Logic,” “Developmental Level,” and “Perseveration.” The drawings of the depressed women showed the high frequency of using only lines without colors or using inappropriate colors. In addition, low implied energy and non-logical or odd elements were found in their drawings. Last, the authors suggested the implications for research and availability of FSA for future studies.
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