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Im, Won Bin,Kim, Yong-Il,Kang, Jong Hyuk,Jeon, Duk Young,Jung, Ha Kyun,Jung, Kyeong Youl Cambridge University Press (Materials Research Soc 2005 Journal of materials research Vol.20 No.8
<P>We optimized synthesis conditions of blue-emitting CaMgSi2O6:Eu<SUP>2+</SUP> (CMS:Eu<SUP>2+</SUP>) with conventional solid-state reaction and successfully determined structure parameters by Rietveld refinement method with neutron powder diffraction data. The final weighted <I>R</I>-factor <I>R</I>wp was 6.42% and the goodness-of-fit indicator <I>S</I> (= <I>R</I>wp/<I>R</I>e) was 1.34. The refined lattice parameters of CMS:Eu<SUP>2+</SUP> were <I>a</I> = 9.7472(3) Å, <I>b</I> = 8.9394(2) Å, and <I>c</I> = 5.2484(1) Å. The β angle was 105.87(1)°. The concentration quenching process was observed, and the critical quenching concentration of Eu<SUP>2+</SUP> in CMS:Eu<SUP>2+</SUP> was about 0.01 mol and critical transfer distance was calculated as 12 Å. With the help of the Rietveld refinement and Dexter theory, the critical transfer distance was also calculated as 27 Å. In addition, the dominant multipolar interaction of CMS:Eu<SUP>2+</SUP> was investigated from the relationship between the emission intensity per activator concentration and activator concentration. The dipole-dipole interaction was a dominant energy transfer mechanism of electric multipolar character of CMS:Eu<SUP>2+</SUP>.</P>
이재임(Jae Im Lee),이인규(In Kyu Lee),이윤석(Yoon Suk Lee),이도상(Do Sang Lee),장석균(Suk Kyun Chang),원종만(Jong Man Won) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.4
Acute necrotizing pancreatitis is a disease with high morbidity and mortality despite the progress made in intensive care. Gas gangrene of the pancreas, usually caused by anaerobe infection, is an extremely rare, but severe form of acute necrotizing pancreatitis. Several severity-of-illness classifications for acute pancreatitis are used to identify patients at risk for complications. Pancreatic necrosis is diagnosed radiographically by dynamic intravenous contrast-enhanced computed tomography (CT) of the abdomen. Early CT in patients with suspected necrotizing pancreatitis contributes to early intervention and many advantageously enhance survival. We report here on two cases of necrotizing pancreatitis with gas gangrene in 49-year-old male patient and 86-year-old female patient.
Kim, Kwang Jong,Kim, Gyeong Heon,Lampande, Raju,Ahn, Dae Hyun,Im, Joon Beom,Moon, Ji Su,Lee, Jae Kyun,Lee, Jae Yeol,Lee, Ju Young,Kwon, Jang Hyuk The Royal Society of Chemistry 2018 Journal of Materials Chemistry C Vol.6 No.6
<P>In this communication, we report an excellent new highly conjugated and rigid electron donor (diindolocarbazole) for thermally activated delayed fluorescence (TADF) emitters. The donor-acceptor structure with diindolocarbazole donor induces high oscillator strength as well as high probability for the radiative transition, suitable frontier molecular overlap with proper intramolecular charge transfer and a large dihedral angle with out-of-plane structure between electron donor and acceptor; this results in high photoluminescence quantum yield, small singlet-triplet energy splitting, and extremely short delayed fluorescence exciton lifetime. The fabricated organic light emitting diode with new donor applied green emitter exhibits a remarkably high external quantum efficiency of 31.4% without any out-coupling technique. It also shows extremely low efficiency roll-off characteristics with the highest luminance of 71 160 cd m<SUP>−2</SUP> as well as good operational device stability.</P>
Second Korean guidelines for the management of Crohn`s disease
( Jae Jun Park ),( Suk-kyun Yang ),( Byong Duk Ye ),( Jong Wook Kim ),( Dong Il Park ),( Hyuk Yoon ),( Jong Pil Im ),( Kang Moon Lee ),( Sang Nam Yoon ),( Heeyoung Lee ) 대한장연구학회 2017 Intestinal Research Vol.15 No.1
Crohn`s disease (CD) is a chronic, progressive, and disabling inflammatory bowel disease (IBD) with an uncertain etiopathogenesis. CD can involve any site of the gastrointestinal tract from the mouth to the anus, and is associated with serious complications, such as bowel strictures, perforations, and fistula formation. The incidence and prevalence rates of CD in Korea are still lower compared with those in Western countries, but they have been rapidly increasing during the recent decades. Although there are no definitive curative modalities for CD, various medical and surgical therapies have been applied for the treatment of this disease. Concerning CD management, there have been substantial discrepancies among clinicians according to their personal experience and preference. To suggest recommendable approaches to the diverse problems of CD and to minimize the variations in treatment among physicians, guidelines for the management of CD were first published in 2012 by the IBD Study Group of the Korean Association for the Study of Intestinal Diseases. These are the revised guidelines based on updated evidence, accumulated since 2012. These guidelines were developed by using mainly adaptation methods, and encompass induction and maintenance treatment of CD, treatment based on disease location, treatment of CD complications, including stricture and fistula, surgical treatment, and prevention of postoperative recurrence. These are the second Korean guidelines for the management of CD and will be continuously revised as new evidence is collected. (Intest Res 2017;15:38-67)
Jung Rock Moon,Chang Kyun Lee,Sung Noh Hong,Jong Pil Im,Byong Duk Ye,Jae Myung Cha,Sung-Ae Jung,Kang-Moon Lee,Dong Il Park,Yoon Tae Jeen,Young Sook Park,Jae Hee Cheon,Hyesung Kim,BoJeong Seo,Youngdoe 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.4
Background/Aims: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score ≥11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (β coefficient: –22.1 for depression and –40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC.
항 Tumor Necrosis Factor 제제 치료 중인 염증성 장질환 환자에서 발생한 결핵의 임상적 특징과 예후
김지혜 ( Jihye Kim ),임종필 ( Jong Pil Im ),임재준 ( Jae-joon Yim ),이창균 ( Chang Kyun Lee ),박동일 ( Dong Il Park ),은창수 ( Chang Soo Eun ),정성애 ( Sung-ae Jung ),신정은 ( Jeong Eun Shin ),이강문 ( Kang-moon Lee ),천재희 ( Jae 대한소화기학회 2020 대한소화기학회지 Vol.75 No.1
Background/Aims: Anti-tumor necrosis factor (TNF) therapy is used widely for the treatment of inflammatory bowel disease (IBD). In the present study, the characteristics and outcomes of tuberculosis (TB) in IBD patients treated with anti-TNF therapy were compared with those of non-IBD TB patients. Methods: Twenty-five IBD patients who initially developed TB during anti-TNF therapy were enrolled in this study. Seventy-five ageand gender-matched non-IBD TB patients were selected as controls in a 1:3 ratio. Results: The proportion of non-respiratory symptoms was higher in the IBD patients than in the non-IBD patients (12 [48.0%] in the IBD patients vs. 15 [20.0%] in the non-IBD patients; p=0.009). Eight (32.0%) IBD patients and 19 (25.3%) non-IBD patients had extra-pulmonary lesions (p=0.516). The frequency of positive smear results for acid-fast bacilli (AFB) was significantly higher in the non-IBD patients than in the IBD patients (three [12.0%] IBD patients vs. 27 [36.0%] non-IBD patients; p=0.023). Active TB was cured in 24 (96.0%) patients in the IBD group and in 70 (93.3%) patients in the non-IBD group (p=0.409). The TB-related mortality rates were 4.0% and 1.3% in the IBD patients and non-IBD patients, respectively (p=0.439). Conclusions: The rate of extrapulmonary involvement, side effects of anti-TB medications, and clinical outcomes did not differ between the IBD patients who initially developed TB during anti-TNF therapy and non-IBD patients with TB. On the other hand, the IBD patients had a lower rate of AFB smear positivity and a higher proportion of non-respiratory symptoms.