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운동부하 검사상 무증상 심근 허혈 환자의 관동맥 병변 소견
조인종(In Jong Cho),서정평(Jung Pyung Suh),류문희(Moon Hee Rheu),이명곤(Myung Kon Lee),박종수(Jong Soo Park),박주형(Joo Hyung Park),정명호(Myung Ho Jeong),조정관(Jeong Gwan Cho),박종춘(Jong Chun Park),강정채(Jung Chaee Kang) 대한내과학회 1994 대한내과학회지 Vol.47 No.5
N/A Objectives: Silent myocardial ischemia is defined as the presence of transient ischemic alterations in absence of angina or its equivalents. In recent reports, silent ischemia comprises about 60-80% of total ischemic events in patients with symptomatic angina and its prognosis is similar to typical painful angina, So, we studied to compare the difference of coronary angiographic features between painful angina and silent angina in patients with positive treadmill exercise test. Method: We studied retrospectively coronary angiographic features of 34 patients; 20 patients with painful treadmill exercise test were grouped in A and 14 patients without pain were grouped in B. Both groups were positive in Thallium corynary perfusion scan. Results: 1) There were no significant differences in sex, age, smoking and hypertension between group A and B but diabetes were more prevalent in group A than in B(p< 0,05) 2) Total exercise duration, ST segment deviation and rate pressure product were not different between two groups in treadmill exercise test. Although treadmill score was significantly low in group A (p<0.05), there was no singificant difference between two groups in case of subtracting treadmill angina index from treadmill score. 3) In dipyridamole Tl scan, defect volume ratio was not different in two groups although defect index was significantly greater in group A(p<0.05). 4) In coronary angiographic findings, there were no sigificant differences in number of stenosed vessels, left ventricular ejection fraction and left ventricular end diastolic pressure, but right coronary artery lesion is more common in group A than group B(p<0,05). 5) The most common clinical diagnosis of studied subject was unstable angina, But there were no statistically difference between two groups. Conclusion: This results suggest that patient with silent myocardial ischemia has similar coronary artery disease to those with painful myocardial ischemia, Early detection and treatment of silent ischemia is essential in the management of ischemic teart disease.
철도 차량 유리창에 발열 유리 시스템 사용시 객실 온도 변화에 대한 연구
안종곤(Ahn jong-kon),유석희(Yoo suk-hee),강범수(Kang beom-su),권진(Kwon-jin),임원석(IM won-suk),강주희(Kang ju-hee) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.5월
건축기술의 발달로 유리가 벽의 구조로 일반화되어 건축되고 있으며. 기존 벽의 역할인 수직 하중을 지탱하는 역할이 없어지게 되었다. 기능과 아름다운 면을 강조하게 되어 벽이 커튼의 역할만 하게 되어 객차 실내 유리창에 접근시 차가운 느낌으로 불쾌감을 유발 한다. 그리고 유리창 아래에 바닥 난방을 했음에도 유리창에 외풍 발생으로 결로 현상이 발생하며 즉 유리창 주변에 물방울이 발생(곰팡이 발생 원인)하여 겨울철 난방 에너지와 여름철 외부 온열이 유리를 통해 이동 하게 된다. 그러므로 에너지효율감소에 절대적으로 영향을 준다. 객차에 발열 유리시스템을 적용하면 유리창 표면에는 냉기의 확산이 발생 하지 않으며. 객차의 실내 냉 난방시 에너지 절감 효과가 있다. To the development of construction techniques and construction of glass-walled structure is generalized. Existing wall to support the role of the vertical load was lose. Features and the beautiful side of the curtain wall job was to be highlighted. Carriage access to the interior of the windows will cause pain in the neck with a cold feeling. And in the windows, drafty windows, under floor heating occurs despite the condensation phenomenon occurs. droplets that occurs around the window (the cause of the mold) in summer and winter, the heat energy and move through the glass is warmer outside. Therefore, to reduce energy efficiency affects absolutely. When you apply heat to the carriage window, the surface of the glass system, the spread of the cold air does not occur. Therefore, energy savings cars and heating of the interior is cold.
Kang, Tong Ho,Oh, Hye Rim,Jung, Sun Moon,Ryu, Jong Hoon,Park, Mee Won,Park, Yong Kon,Kim, Sun Yeou Pharmaceutical Society of Japan 2006 Biological & pharmaceutical bulletin Vol.29 No.2
<P>Several neurological disorders such as Alzheimer's and Parkinson's diseases have been attributed to γ-aminobutyric acid (GABA) depletion in the brain. In order to provide a pharmacological basis for the neuroprotective actions of the enhanced accumulation of GABA in mulberry leaves (ML) against cerebral ischemia <I>in vitro</I> and <I>in vivo</I>, a process was developed to enhance the accumulation of GABA in mulberry leaves (GAML) as a result of the various anaerobic treatments. The GABA concentrations were changed by N<SUB>2</SUB> gas purging, the reaction temperature, reaction time, pH and the leaf size. GABA enhanced the potential of neuroprotection in the PC12 cells damaged by H<SUB>2</SUB>O<SUB>2</SUB>-induced oxidation. GAML reduced the cytotoxicity in the PC12 cells against oxygen glucose deprivation-induced cerebral ischemic condition. The neuroprotective effect of GAML was further demonstrated <I>in vivo</I> using middle cerebral artery occlusion brain injury model. GAML significantly decreased the infarct volume of the brain compared with than control group. Overall, these results suggest that the anaerobic treatment of ML makes GAML enhance the neuroprotection effect against <I>in vivo</I> cerebral ischemia such as <I>in vitro</I>.</P>
Characterization of Heat Reformed Naphtha Cracking Bottom Oil Extracts
Jong-Hyun Oh,Jae-Young Lee,Seok-Hwan Kang,Tai-Hyung Rhee,Seung-Kon Ryu 한국탄소학회 2008 Carbon Letters Vol.9 No.4
Naphtha Cracking Bottom (NCB) oil was heat reformed at various reforming temperature and time, and the volatile extracts were characterized including yields, molecular weight distributions, and representative compounds. The yield of extract increased as the increase of reforming temperature (360~420℃) and time (1~4 hr). Molecular weight of the as-received NCB oil was under 200, and those of extracts were distributed in the range of 100-250, and far smaller than those of precursor pitches of 380-550. Naphtalene-based compounds were more than 70% in the as-received NCB oil, and most of them were isomers of compounds bonding functional groups, such as methyl (CH3-) and ethyl (C2H5-). When the as-received NCB oil was reformed at 360℃ for 1 hr, the most prominent compound was 1,2-Butadien, 3-phenyl- (24.57%), while naphthalene became main component again as increasing the reforming temperature.
Kang, Chang Wan,Choi, Jaewon,Ko, Ju Hong,Kim, Sung-Kon,Ko, Yoon-Joo,Lee, Sang Moon,Kim, Hae Jin,Kim, Jong Pil,Son, Seung Uk Royal Society of Chemistry 2017 Journal of Materials Chemistry A Vol.5 No.12
<P>Pure silica zeolite (Silicalite-1) bricks with a 2D morphology were assembled on a slide glass and used as templates for the preparation of microstructured organic network films (MONFs) with a hollow space and holes by the Sonogashira coupling of tetrakis(4-ethynylphenyl)methane and 1,4-diiodobenzene and silica etching. The MONFs were adhesive to polyethylene terephthalate (PET) films due to their unique structural effects. Cu was loaded on the MONF/PET by electroless deposition. The Cu/MONF/PET showed excellent retention of conductivities in repeated severe bending.</P>
Kang, Doo Seok,Yang, Jun Hyuek,Kim, Hyun Soo,Koo, Bon Kon,Lee, Cheol Min,Ahn, Yeon-Soon,Jung, Jong-Hyeon,Seo, Young Rok Korean Society of Cancer Prevention 2018 Journal of cancer prevention Vol.23 No.3
<P>As industry develops in modern society, many chemicals are being used. The safety of chemicals is an important issue because humans are constantly exposed to chemicals throughout their daily life. Through a risk assessment, the hazardous human effects of chemicals can be identified. Recently, the adverse outcome pathway (AOP) framework has been used to predict the adverse effects of chemicals. As a conceptual framework for organizing existing biological knowledge, the AOP consists of a molecular initiating event, key events, and an adverse outcome. These independent elements represent biological responses and are connected by key event relationships. This AOP framework provides intuitive hazard identification that can be helpful for carcinogenic risk assessment of chemicals. In this review, we introduce the application of the AOP framework to risk assessment for predicting carcinogenicity of chemicals and illustrate the utility of this approach for cancer prevention.</P>