Learning from an Expert Teacher: Feynman's Teaching of Gravitation as an Examplar

Park, Jiyun,Lee, Gyoungho,Kim, Jiwon,Treagust, David F. Science Education Research Institute Kyungpook Nat 2019 科學敎育硏究誌 Vol.43 No.1

An expert teachers' instruction can be helpful to other teachers because good teaching effectively guides students to develop meaningful learning. Feynman is an excellent physics lecturer as well as one of the greatest physicists of the 20th century who presented and explained physics with his unique teaching style based on his great store of knowledge. However, it is not easy to capture and visualize teaching because it is not only the complex phenomena interrelated to various factors with the content to be taught but also the tacit representation. In this study, the framework of knowledge & belief based on the integrated mental model theory was used as a tool to capture and visualize complex and tacit representation of Feynman's teaching of 'The theory of gravitation,' a chapter in The Feynman Lectures on Physics. Feynman's teaching was found to go beyond the transmission of physics concepts by showing that components of the framework of knowledge & belief were effectively intertwined and integrated in his teaching and the storyline was well-organized. On the basis of these discussions, the implications of Feynman's teaching analyzed within the framework of knowledge & belief for physics teacher education are derived. Finally, the characteristics of the framework of knowledge & belief as tools for the analysis of teaching are presented.

Overexpression of Neuron-Specific Enolase as a Prognostic Factor in Patients with Gastric Cancer

Park, Taejin,Lee, Young-Joon,Jeong, Sang-Ho,Choi, Sang-Kyung,Jung, Eun-Jung,Ju, Young-tae,Jeong, Chi-Young,Park, Miyeong,Hah, Young-Sool,Yoo, Jiyun,Ha, Woo-Song,Hong, Soon-Chan,Ko, Gyung Hyuck The Korean Gastric Cancer Association 2017 Journal of gastric cancer Vol.17 No.3

Purpose: Enolase is a cytoplasmic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. The aim of this study was to investigate whether the overexpression of neuron-specific enolase (NSE) can serve as a prognostic factor in patients with gastric cancer (GC). Materials and Methods: To assess its prognostic value in GC, NSE expression was measured by immunohistochemistry in a clinically annotated tissue microarray comprising of 327 human GC specimens. Cytoplasmic NSE expression was scored from 0 to 4, reflecting the percentage of NSE-positive cells. Results: In terms of histology as per the World Health Organization criteria (P=0.34), there were no differences between the NSE overexpression (NSE-OE) and NSE underexpression (NSE-UE) groups. The NSE-OE group showed a significantly lower rate of advanced GC (P<0.01), lymph node metastasis (P=0.01), advanced stage group (P<0.01), cancer-related death (P<0.01), and cancer recurrence (P<0.01). Additionally, a Kaplan-Meier survival analysis revealed that the NSE-OE group had longer cumulative survival times than the NSE-UE group (log-rank test, P<0.01). However, there were no significant differences in the serum levels of NSE expression in patients with GC and healthy volunteers (P=0.28). Conclusions: Patients with NSE overexpressing GC tissues showed better prognostic results, implying that NSE could be a candidate biomarker of GC.

Scaling of binding affinities and cooperativities of surfactants on carbon nanotubes

Park, Minsuk,Park, Junmo,Lee, Jiyun,Ju, Sang-Yong Elsevier 2018 Carbon Vol.139 No.-

<P><B>Abstract</B></P> <P>High-end applications of single-walled carbon nanotube (SWNT) require detailed understanding of their binding affinity (<I>K</I> <SUB>d</SUB>) with surfactants. Here, we quantitatively determined the comprehensive <I>K</I> <SUB>d</SUB> and aggregation number (γ) of nine nonionic and anionic surfactants according to SWNT chirality. Photoluminescence (PL)-based titration using flavin mononucleotide (FMN)-SWNT complexes showing the largest redshifted optical transition enabled quantitative comparison of the surfactants and displayed distinct first and second regimes which correspond to partial and full replacements of FMN, respectively. Especially, the second transition exhibited sigmoidal PL change whose middle point denoted by the inverse of <I>K</I> <SUB>d</SUB> slightly differs from critical micelle concentration of surfactant alone, depending on its functional groups. Moreover, nonionic surfactants displayed larger <I>K</I> <SUB>d</SUB> and lower γ values than the anionic did. Specifically, <I>K</I> <SUB>d</SUB> values between Pluronic F108 and sodium dodecyl sulfonate differ by four orders of magnitude. Such differences were rationalized in terms of the occupied volume of the micelle based on the hydrodynamic volume and γ. During the replacement, <I>K</I> <SUB>d</SUB> and γ were affected by the degree of surfactant rearrangement induced by aging process, leading to more stable complex. Scaling the interactions between surfactant and SWNT provides useful guidelines to design novel SWNT sorting method using more than two surfactants.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

The physical and emotional health of South Korean mothers of preterm infants in the early postpartum period: a descriptive correlational study

Jiyun Park,Kyung-Sook Bang 한국아동간호학회 2022 Child Health Nursing Research Vol.28 No.2

Purpose: This study investigated the physical and emotional health of South Korean mothers of preterm infants in the early postpartum period. Methods: In this descriptive correlational study, the participants included 91 mothers of preterm infants who were admitted to the neonatal intensive care unit of a tertiary hospital in South Korea. Physical health status was measured using a self-reported questionnaire, postpartum depression using the Edinburgh Postnatal Depression Scale, anxiety using the State-Trait Anxiety Inventory, and guilt using a 4-item scale. Results: Fatigue had the highest score among mothers' physical health problems, followed by shoulder pain, nipple pain, neck pain. The average postpartum depression score was 11.02 points, and 44% of women had postpartum depression with a score of 12 or above. Postpartum depression significantly was correlated with physical health (r=.35, p=.001), anxiety (r=.84, p<.001), and guilt (r=.75, p<.001) and was significantly higher for women with multiple births, and preterm infants who required ventilator and antibiotic treatment. Anxiety also showed a significant difference according to preterm infants’ condition. Conclusion: The significant correlations between postpartum depression and physical health, anxiety, and guilt indicate a need for nursing interventions that provide integrated management of mothers’ physical and emotional health.

Metal Ion Effect on the Switch of Mechanism from Direct Oxygen Transfer to Metal Ion-Coupled Electron Transfer in the Sulfoxidation of Thioanisoles by a Non-Heme Iron(IV)−Oxo Complex

Park, Jiyun,Morimoto, Yuma,Lee, Yong-Min,Nam, Wonwoo,Fukuzumi, Shunichi American Chemical Society 2011 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.133 No.14

<P>The mechanism of sulfoxidation of thioaniosoles by a non-heme iron(IV)−oxo complex is switched from direct oxygen transfer to metal ion-coupled electron transfer by the presence of Sc<SUP>3+</SUP>. The switch in the sulfoxidation mechanism is dependent on the one-electron oxidation potentials of thioanisoles. The rate of sulfoxidation is accelerated as much as 10<SUP>2</SUP>-fold by the addition of Sc<SUP>3+</SUP>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2011/jacsat.2011.133.issue-14/ja200901n/production/images/medium/ja-2011-00901n_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja200901n'>ACS Electronic Supporting Info</A></P>

Scandium Ion-Enhanced Oxidative Dimerization and <i>N</i>-Demethylation of <i>N</i>,<i>N</i>-Dimethylanilines by a Non-Heme Iron(IV)-Oxo Complex

Park, Jiyun,Morimoto, Yuma,Lee, Yong-Min,You, Youngmin,Nam, Wonwoo,Fukuzumi, Shunichi American Chemical Society 2011 Inorganic Chemistry Vol.50 No.22

<P>Oxidative dimerization of <I>N</I>,<I>N</I>-dimethylaniline (DMA) occurs with a nonheme iron(IV)-oxo complex, [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP> (N4Py = <I>N</I>,<I>N</I>-bis(2-pyridylmethyl)-<I>N</I>-bis(2-pyridyl)methylamine), to yield the corresponding dimer, tetramethylbenzidine (TMB), in acetonitrile. The rate of the oxidative dimerization of DMA by [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP> is markedly enhanced by the presence of scandium triflate, Sc(OTf)<SUB>3</SUB> (OTf = CF<SUB>3</SUB>SO<SUB>3</SUB><SUP>–</SUP>), when TMB is further oxidized to the radical cation (TMB<SUP>•+</SUP>). In contrast, we have observed the oxidative N-demethylation with <I>para</I>-substituted DMA substrates, since the position of the C–C bond formation to yield the dimer is blocked. The rate of the oxidative N-demethylation of <I>para</I>-substituted DMA by [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP> is also markedly enhanced by the presence of Sc(OTf)<SUB>3</SUB>. In the case of <I>para</I>-substituted DMA derivatives with electron-donating substituents, radical cations of DMA derivatives are initially formed by Sc<SUP>3+</SUP> ion-coupled electron transfer from DMA derivatives to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>, giving demethylated products. Binding of Sc<SUP>3+</SUP> to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP> enhances the Sc<SUP>3+</SUP> ion-coupled electron transfer from DMA derivatives to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>, whereas binding of Sc<SUP>3+</SUP> to DMA derivatives retards the electron-transfer reaction. The complicated kinetics of the Sc<SUP>3+</SUP> ion-coupled electron transfer from DMA derivatives to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP> are analyzed by competition between binding of Sc<SUP>3+</SUP> to DMA derivatives and to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>. The binding constants of Sc<SUP>3+</SUP> to DMA derivatives increase with the increase of the electron-donating ability of the <I>para</I>-substituent. The rate constants of Sc<SUP>3+</SUP> ion-coupled electron transfer from DMA derivatives to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>, which are estimated from the binding constants of Sc<SUP>3+</SUP> to DMA derivatives, agree well with those predicted from the driving force dependence of the rate constants of Sc<SUP>3+</SUP> ion-coupled electron transfer from one-electron reductants to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>. Thus, oxidative dimerization of DMA and N-demethylation of <I>para-</I>substituted DMA derivatives proceed via Sc<SUP>3+</SUP> ion-coupled electron transfer from DMA derivatives to [Fe<SUP>IV</SUP>(O)(N4Py)]<SUP>2+</SUP>.</P><P>Competition between binding of Sc<SUP>3+</SUP> ion to <I>N</I>,<I>N</I>-dimethylaniline (DMA) derivatives and a non-heme iron(IV)-oxo complex results in overall enhancement of electron transfer from DMA derivatives to a non-heme iron(IV)-oxo complex, leading to oxidative dimerization of DMA and N-demethylation of para-substituted DMA.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/inocaj/2011/inocaj.2011.50.issue-22/ic201545a/production/images/medium/ic-2011-01545a_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ic201545a'>ACS Electronic Supporting Info</A></P>

A Pilot Study about Possible Gluten Sensitivity in Korean Urticaria Patients

( Jiyun Park ),( Daewook Lee ),( Seung Hwi Kwon ),( Jin Young Song ),( Yoo Sang Baek ),( Jiehyun Jeon ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.5

Learning from an Expert Teacher: Feynman’s Teaching of Gravitation as an Examplar

( Jiyun Park ),( Gyoungho Lee ),( Jiwon Kim ),( David F. Treagust ) 경북대학교 과학교육연구소 2019 科學敎育硏究誌 Vol.43 No.1

An expert teachers’ instruction can be helpful to other teachers because good teaching effectively guides students to develop meaningful learning. Feynman is an excellent physics lecturer as well as one of the greatest physicists of the 20th century who presented and explained physics with his unique teaching style based on his great store of knowledge. However, it is not easy to capture and visualize teaching because it is not only the complex phenomena interrelated to various factors with the content to be taught but also the tacit representation. In this study, the framework of knowledge & belief based on the integrated mental model theory was used as a tool to capture and visualize complex and tacit representation of Feynman’s teaching of ‘The theory of gravitation,’ a chapter in The Feynman Lectures on Physics. Feynman’s teaching was found to go beyond the transmission of physics concepts by showing that components of the framework of knowledge & belief were effectively intertwined and integrated in his teaching and the storyline was well-organized. On the basis of these discussions, the implications of Feynman’s teaching analyzed within the framework of knowledge & belief for physics teacher education are derived. Finally, the characteristics of the framework of knowledge & belief as tools for the analysis of teaching are presented.

Near-lossless Image Compression Algorithm to Reduce the Memory Bandwidth of Display Devices

Jiyun Park,Jihoon Choi,Dong Yoon Choi,Byung Cheol Song 대한전자공학회 2019 IEIE Transactions on Smart Processing & Computing Vol.8 No.6

Recently, as the spread of ultra-high definition (UHD) display devices has become more active, considerable data bandwidth is required between the display and external memory. Compression of data can be applied to reduce memory bandwidth, but that can lead to degradation of image quality. So, in this paper, we propose a near-lossless compression algorithm that reduces memory bandwidth and minimizes image quality degradation for hardware implementation. The proposed algorithm is based on two-line memory–based prediction and transformation. Also, it improves the performance of quantization through one-dimensional (1-D) discrete cosine transform (DCT). In rate control, quantization parameters are determined using both horizontal and vertical information to improve efficiency. Finally, a partial update is implemented to enable selective decoding of images. Experimental results show that the proposed method is superior in terms of peak signal-to-noise ratio while maintaining a high compression ratio.

Identification of a novel PSEN1 mutation (Leu232Pro) in a Korean patient with early-onset Alzheimer's disease and a family history of dementia

Park, Jiyun,An, Seong Soo A.,Giau, Vo Van,Shim, Kyuhwan,Youn, Young Chul,Bagyinszky, Eva,Kim, SangYun Elsevier 2017 NEUROBIOLOGY OF AGING Vol.56 No.-

<P><B>Abstract</B></P> <P>In the present study, a novel mutation in exon 7 of presenilin 1 (Leu232Pro) was discovered in a Korean patient with early-onset Alzheimer's disease, who represented memory decline at 37 years of age, followed by impairment in spatial activity and concentrations and personality changes. Imaging analyses with magnetic resonance scan showed diffuse atrophy in the frontoparietal regions. Targeted next generation sequencing and Sanger sequencing identified a heterozygous T to C transition at position 695 (c.695T>C) of in presenilin 1 gene (<I>PSEN1</I>), resulting in a novel missense mutation at codon 232 from leucine to proline (L232P). Several family members of the patient developed dementia, suggesting an autosomal dominant inheritance; however, we were unable to perform a segregation analysis to confirm this. Since the proline may play a role as a helix breaker, this mutation could significantly disturb the transmembrane helix domain-V of PSEN1 and perturb its protein functions. This hypothesis was supported by the results from the in silico analyses, predicted a major kink on this helix. Several leucine>proline substitutions in other PSEN1 transmembrane helices revealed aggressive AD phenotypes. Future functional studies would be needed to evaluate the pathogenicity of this mutation in AD.</P>