The antioxidant components from one north China mountain herb, Ledum palustre L

XU Jiu Liang,SHANG Ya Fang,PEI Shi Chun,LEE Won Jong,KANG Suk Woo,UM Byung Hun 대한약학회 2012 大韓藥學會 總會 및 學術大會 Vol.2012 No.1

Simultaneous roasting and extraction of green coffee beans by pressurized liquid extraction

Xu, Jiu Liang,Kim, Tae Jin,Kim, Jae-Kwang,Choi, Yongsoo Elsevier 2019 Food chemistry Vol.281 No.-

<P><B>Abstract</B></P> <P>Green coffee extracted by pressurized liquid extraction (PLE) was found to undergo a roasting process similar to traditional roasting. Liquid chromatography-tandem mass spectrometry was used to investigate the chlorogenic acid (CGA) composition and profiling changes by PLE under different extraction conditions and showed almost identical generation and degradation of CGAs occurring during traditional coffee roasting. Compared with the traditional extraction of roasted coffee, optimized PLE coffee showed three- and two-fold higher antioxidant activity and total CGA contents, respectively.</P> <P>Composition diversity and the content of volatile compounds in PLE coffee were found to increase as the PLE temperature increased but were lower than those of traditionally roasted coffee. The sensory attributes of PLE coffee were also evaluated to have be associated with a profile change in the volatile compounds and non-volatile CGA compounds.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Green coffee beans were found to undergo a roasting process by pressurized liquid extraction (PLE). </LI> <LI> Optimized PLE conditions showed almost identical compositions of CGAs occurring during traditional coffee roasting. </LI> <LI> PLE roasting process showed three-fold higher antioxidant activity than traditional extraction of roasted coffee. </LI> <LI> PLE roasting and extraction can be utilized for the development of functional coffee products. </LI> </UL> </P>

Differences in the metabolic profiles and antioxidant activities of wild and cultivated black soybeans evaluated by correlation analysis

Xu, Jiu Liang,Shin, Jeong-Sook,Park, Soo-Kwon,Kang, Sungtaeg,Jeong, Soon-Chun,Moon, Jung-Kyung,Choi, Yongsoo Elsevier Science B.V., Amsterdam. 2017 Vol. No.

<P>Wild soybeans are considered a potential resource for soybean domestication and an important source of genetic diversity for soybean crop improvement. Understanding metabolite-caused bioactivity differences between cultivated and wild soybeans is essential for designing a soybean with enhanced nutritional traits. In this study, the non-targeted metabolic profiling of 26 soybean varieties, 15 wild black soybeans (WBS) and 11 cultivated black soybeans (CBS), using liquid chromatography-mass spectrometry (LC-MS) in combination with multivariate analysis revealed significant differences in 25 differential metabolites. Among these, the soyasaponins Ab and Bb were found to be characteristic metabolites expressed more substantially in CBS than in WBS. Three different antioxidant assays and correlation analysis identified major and minor antioxidants that contributed to WBS having an antioxidant activity 4- to 8-fold stronger than that of CBS. Epicatechin, procyanidin B2, and cyanidin-3-O-glucoside were identified by both association analysis and the online LC-ABTS radical scavenging assay as being major antioxidants.</P>

Association study between metabolomic profiling and bioactivity of crop diversity

Jiu Liang Xu,Jeong-Sook Shin,Yongsoo Choi 한국분석과학회 2017 학술대회논문집 Vol.2017 No.11

반응표면분석법을 사용한 가속 용매 추출에 의한 홍삼 지표성분의 추출 최적화

김은옥(Eun Ok Kim),서구량(Jiu Liang Xu),엄병헌(Byung Hun Um) 한국식품영양과학회 2016 한국식품영양과학회지 Vol.45 No.8

본 연구에서는 기능성 홍삼 엑기스 제조를 위해 추출용매, 압력, 온도, 추출시간을 조절하여 가속 용매 추출한 후 기능성 홍삼제품의 지표성분인 진세노사이드 함량, 총페놀화합물 및 벤조피렌 함량 등을 조사하였다. 홍삼 가속 용매 추출 최적화를 위한 독립변수 선택을 위해 에탄올 농도, 압력, 온도 및 추출시간에 따른 기능성 홍삼제품의 지표성분인 진세노사이드 Rb1, Rg1 및 Rg3(20S) 함량의 합을 분석하여 진세노사이드 추출에 가장 최적의 용매를 50% 에탄올로 하고, 영향이 다소 작았던 요인인 압력을 2,500 psi로 설정하였으며, 온도와 추출시간을 독립변수로 설정하였다. 추출 온도 및 시간을 독립변수로 하여 고온고압 처리한 홍삼의 진세노사이드 Rb1, Rg1 및 Rg3(20S) 함량의 합, 총 페놀성 화합물 및 벤조피렌 함량을 측정한 결과, 벤조피렌이 검출되지 않는 조건에서 진세노사이드 Rb1, Rg1 및 Rg3(20S)의 함량 합이 최적화된 조건은 158°C, 20분임을 확인할 수 있었다. 최적화된 조건에서의 가속 용매 추출 시 초음파 및 환류냉각 추출에 비해 적은 용매로 단시간 추출하면서 진세노사이드 Rb1, Rg1 및 Rg3(20S) 함량 합 및 총폴리페놀 함량이 각각 1.5~2배 및 2.2~5배 높게 추출할 수 있어 효율적인 추출방법이 될 것으로 생각된다. A new method based on accelerated solvent extraction (ASE) combined with response surface methodology (RSM) has been developed for optimization of the extraction of ginsenoside [Rb1, Rg1, and Rg3(20S)], total phenolics, and benzopyrene in red ginseng. The RSM method, based on a five level and two variable central composite design, was employed to obtain the optimal combination of extraction conditions. In brief, ginsenosides Rb1, Rg1, and Rg3(20S) and total phenolics with undetectable benzopyrene were optimally extracted with 50% ethanol as an extraction solvent, extraction temperature of 158°C, extraction time of 20 min, extraction pressure of 2,500 psi, flush volume of 60%, and one extraction cycle. The contents of ginsenosides and total phenolics in red ginseng extracted by ASE under optimum conditions were significantly higher than those extracted by sonication and reflux extraction.

Exergo-economic analysis of finned tube for waste heat recovery including phase change heat transfer

Shuang-Ying Wu,Jing-Rui Jiu,Lan Xiao,You-Rong Li,Chao Liu,Jin-Liang Xu 대한기계학회 2013 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.27 No.11

In this paper, an exergo-economic criterion, i.e. the net profit per unit transferred heat load, is established from the perspective of exergy recovery to evaluate the performance of finned tube used in waste heat recovery. Also, the dimensionless exergy change number is introduced to investigate the effect of the flow (mechanical) exergy loss rate on the recovered thermal exergy. Selecting R245fa as a working fluid and exhaust flue gas as a heat source, the effects of the internal Reynolds number Rei, the external Reynolds number Reo, the unit cost of thermal exergy εq, the geometric parameter of finned tube ηoβ and the phase change temperature Tv etc. on the performance of finned tube are discussed in detail. The results show that the higher Tv and ηoβ, and lower Rei may lead to the negligible flow (mechanical) exergy loss rate. There exists an optimal value of Rei where the net profit per unit transferred heat load peaks, while the variations of Reo, εq and Tv cause monotonic change of the net profit per unit transferred heat load. The phase change temperature exerts relatively greater influence on the exergo-economic performance of finned tube in comparison with other parameters. And there exists a critical phase change temperature, where the net profit per unit transferred heat load is equal to zero.

Anti-neuroinflammatory Effects of 12-Dehydrogingerdione in LPS-Activated Microglia through Inhibiting Akt/IKK/NF-κB Pathway and Activating Nrf-2/HO-1 Pathway

Dong Zhao,Ming-Yao Gu,Jiu Liang Xu,Li Jun Zhang,Shi Yong Ryu,양현옥 한국응용약물학회 2019 Biomolecules & Therapeutics(구 응용약물학회지) Vol.27 No.1

Ginger, one of worldwide consumed dietary spice, is not only famous as food supplements, but also believed to exert a variety of remarkable pharmacological activity as herbal remedies. In this study, a ginger constituent, 12-dehydrogingerdione (DHGD) was proven that has comparable anti-inflammatory activity with positive control 6-shogaol in inhibiting LPS-induced interleukin (IL)-6, tumor necrosis factor (TNF)-α, prostaglandin (PG) E2, nitric oxide (NO), inducible NO synthase (iNOS) and cyclooxygenase (COX)-2, without interfering with COX-1 in cultured microglial cells. Subsequent mechanistic studies indicate that 12-DHGD may inhibit neuro-inflammation through suppressing the LPS-activated Akt/IKK/NF-κB pathway. Furthermore, 12-DHGD markedly promoted the activation of NF-E2-related factor (Nrf)-2 and heme oxygenase (HO)-1, and we demonstrated that the involvement of HO-1 on the production of pro-inflammatory mediators such as NO and TNF-α by using a HO-1 inhibitor, Zinc protoporphyrin (Znpp). These results indicate that 12-DHGD may protect against neuro-inflammation by inhibiting Akt/IKK/IκB/NF-κB pathway and promoting Nrf-2/HO-1 pathway.

Designing Co7Fe3@TiO2 Core–Shell Nanospheres for Electromagnetic Wave Absorption in S and C Bands

Na Chen,Jian‑Tang Jiang,Zhen‑Jie Guan,Shao‑Jiu Yan,Liang Zhen,Cheng‑Yan Xu 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.5

Ferromagnetic-dielectric nanocomposites have attracted extensive interests for its high electromagnetic wave absorption(EMA) performance due to the synergetic effects between different components. Herein, we report the design of core–shellstructured Co7Fe3@TiO2 composite particles, which are subsequently annealed in H2/Ar atmosphere to further improve itsEMA performance. The introducing of TiO2dielectric shell together with hydrogen annealing contributes greatly to theelectromagnetic properties due to the increased conductivity and enhanced ferromagnetic resonance. Excellent EMA performanceis achieved in S (2–4 GHz) and C (4–8 GHz) bands in coatings using Co7Fe3@TiO2 as absorbents. Apart from thehigh EMA efficiency, the location of EMA band can be tailored in a wide range through regulating the coating thickness. Specifically, an effective absorption band of 2.0 GHz in C band at a thickness of 2.62 mm, and an effective absorption bandof 1.7 GHz are achieved in S band at thicknesses of 4.0–5.0 mm. The excellent electromagnetic properties are ascribed tothe effective complementary between dielectric loss and ferromagnetic loss.