http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Jing Zhai (검색결과 27 건)
- 무료
- 기관 내 무료
- 유료
-
Jing Zhai,Weishan Chang,Zhenzhen Zhai,Xingliang Ma,Lingling Yang,Jinfeng Ti,Daozhen Song,Shijun Fu,Dapeng Li 한국유전학회 2016 Genes & Genomics Vol.38 No.8
Few studies have attempted to characterize the pheasant (Phasianus colchicus) immunoglobulin Y (IgY) heavy chain constant region. In the present study, fragments of the pheasant IgY heavy chain constant region were cloned, analyzed, and expressed. The cross-reactivity of IgY or immunoglobulin G (IgG)s with antigens from other vertebrate species was determined using dot-enzymelinked immunosorbent assay and western blot analysis. Five peptides of the pheasant IgY heavy chain constant region were synthesized to determine its immunoregulatory activity in vitro. The IgY heavy chain constant region from pheasant showed the highest homology with that from chicken (71.2 %) and duck (49.1 %). Phylogenetic analysis for IgY showed that pheasant was closely related to chicken and duck than to any other analyzed vertebrate species. The rabbit anti-chicken IgG showed immunologic cross-reactivity with recombinant proteins of the pheasant IgY heavy chain constant region. Four peptides were able to induce significant up-regulation of interleukin (IL)-1b, IL-4, and interferon-c in chicken peripheral blood lymphocytes, suggesting a new role of avian IgY in immune regulation.
-
Expression of Annexin A3 in Gastric Cancer and its Correlation with Proliferation and Apoptosis
Zhai, Jing-Ming,Sun, Shi-Jun,Wang, Wei,Zeng, Chao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7
Annexin A3 has been identified as a novel biomarker in different types of cancers. However, little is known about its clinical significances and and biological roles in gastric cancer. In this study, we assessed annexin A3 expression in 80 patients with gastric cancer and explore its correlation with prognosis Moreover, correlations with Ki-67, Bcl-2 and Bax were also investigated. Expression of annexin A3 was increased in gastric cancer compared with that in normal gastric tissues. Annexin A3 expression was significantly associated with tumor volume and TNM stage (p<0.05). and inversely correlation with prognosis of patients. More interestingly, expression of annexin A3 was positive correlated with Ki-67 and Bcl-2 expression. Our study showed annexin A3 might be a potential prognostic marker for gastric cancer and involved in tumorigenesis by regulating apoptosis and proliferation.
-
Zhai Linhan,Wang Qiuxia,Liu Ping,Luo Ban,Yuan Gang,Zhang Jing 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.6
Objective: To evaluate the performance of baseline clinical characteristics and pretherapeutic histogram parameters derived from T2 mapping of the extraocular muscles (EOMs) in the prediction of treatment response to intravenous glucocorticoid (IVGC) therapy for active and moderate-to-severe thyroid-associated ophthalmopathy (TAO) and to investigate the effect of fat-suppression (FS) in T2 mapping in this prediction. Materials and Methods: A total of 79 patients clinically diagnosed with active, moderate-to-severe TAO (47 female, 32 male; mean age ± standard deviation, 46.1 ± 10 years), including 43 patients with a total of 86 orbits in the responsive group and 36 patients with a total of 72 orbits in the unresponsive group, were enrolled. Baseline clinical characteristics and pretherapeutic histogram parameters derived from T2 mapping with FS (i.e., FS T2 mapping) or without FS (i.e., conventional T2 mapping) of EOMs were compared between the two groups. Independent predictors of treatment response to IVGC were identified using multivariable analysis. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive performance of the prediction models. Differences between the models were examined using the DeLong test. Results: Compared to the unresponsive group, the responsive group had a shorter disease duration, lower kurtosis (FSkurtosis), lower standard deviation, larger 75th, 90th, and 95th (FS-95th) T2 relaxation times in FS mapping and lower kurtosis in conventional T2 mapping. Multivariable analysis revealed that disease duration, FS-95th percentile, and FS-kurtosis were independent predictors of treatment response. The combined model, integrating all identified predictors, had an optimized area under the ROC curve of 0.797, 88.4% sensitivity, and 62.5% specificity, which were significantly superior to those of the imaging model (p = 0.013). Conclusion: An integrated combination of disease duration, FS-95th percentile, and FS-kurtosis was a potential predictor of treatment response to IVGC in patients with active and moderate-to-severe TAO. FS T2 mapping was superior to conventional T2 mapping in terms of prediction.
-
Molecularly Imprinted Polymer Coating with Fluorescence on Magnetic Particle
Jing Huang,Haiqing Liu,Haifen Men,Yunyun Zhai,Qihui Xi,Zulei Zhang,Jian Zhang,Zhengzhi Yin,Lei Li 한국고분자학회 2013 Macromolecular Research Vol.21 No.9
In this research, molecular imprinting technology was employed to prepare magnetic, fluorescent molecularly imprinted polymer microspheres (fluorescent M-MIP) for recognition and separation of endocrine disrupting chemicals. The fluorescent M-MIP were prepared using Fe3O4@SiO2 magnetic nanoparticles combined with fluorescein (isothiocyanate) as fluorescent material with the surface molecularly imprinting method. The magnetic fluorescent molecularly imprinted polymers were characterized by fluorescence spectrophotometer, X-ray powder diffraction,vibration sample magnetic field meter, scanning and transmission electron microscopic methods. The results showed that the fluorescent M-MIP not only had excellent superparamagnetism and maintained the crystalline structure of the magnetic nanoparticles, but also stable fluorescence. The recognition selectivity of the magnetic fluorescence polymer was studied for template molecule and analogues. The results indicated that the fluorescent quenches of bisphenol A (the selective target) for fluorescent M-MIP were higher than that of the structural analogues, which illustrated the recognition selectivity for bisphenol A. Simultaneously, the fluorescent magnetic non-imprinted polymers (M-NIPs) had much higher fluorescent quenches than the fluorescent M-NIPs in the processes of rebinding. Therefore, the fluorescent M-MIP technology can be used for the recognition, magnetic separation and detection of bisphenol A by fluorescence spectrometry without any time-consuming elution.
-
Finite Frequency Fault Detection for T-S Fuzzy Singular Multiple Timedelay Systems
Ding Zhai,Li-Wei An,Jing-Hao Li,Qing-Ling Zhang 제어·로봇·시스템학회 2016 International Journal of Control, Automation, and Vol.14 No.4
This paper focuses on the problem of fault detection (FD) for a class of nonlinear systems describedby the T-S fuzzy singular model with multiple time delays and actuator faults. Two finite-frequency performanceindices are introduced to measure fault sensitivity and disturbance robustness. To reduce the conservatism of theexisting results, a finite frequency domain approach to fuzzy singular multiple time-delay systems is proposed. Then based on the approach, filter design conditions for the solvability of this problem are presented in terms oflinear matrix inequalities (LMIs). Finally, simulation studies are provided to demonstrate the application of theproposed method.
-
Xiang Zhai,Xin-yang Li,Yu-jing Wang,Ke-ru Qin,Jin-rui Hu,Mei-ning Li,Hai-long Wang,Rui Guo 대한내분비학회 2022 Endocrinology and metabolism Vol.37 No.3
Background: It is well-established that serum testosterone in men decreases with age, yet the underlying mechanism of this changeremains elusive. Methods: The expression patterns of Fancd2 opposite-strand (Fancd2os) in BALB/c male mice and testicular tissue derived celllines (GC-1, GC-2, TM3, and TM4) were assessed using real-time polymerase chain reaction (RT-PCR), Western blot and immunofluorescence. The Fancd2os-overexpressing or knockdown TM3 cells were constructed by infecting them with lentivirus particlesand were used to evaluated the function of Fancd2os. The testosterone production was measured using enzyme linked immunosorbent assay (ELISA) and the steroidogenic enzymes such as steroidogenic acute regulatory protein (StAR), P450 cholesterol sidechain cleavage (P450scc), and 3β-hydroxysteroid dehydrogenase (3β-HSD) were analysed using RT-PCR. The apoptosis of TM3cells induced by ultraviolet light or testicular tissues was detected using flow cytometry, Western blot or dUTP-biotin nick end labeling (TUNEL) assays. Pearson correlation analysis was used to assess the correlation between the Fancd2os expression and TUNELpositive staining in mouse testicular Leydig cells. Results: The Fancd2os protein was predominantly expressed in mouse testicular Leydig cells and its expression increased with age. Fancd2os overexpression inhibited testosterone levels in TM3 Leydig cells, whereas knockdown of Fancd2os elevated testosteroneproduction. Fancd2os overexpression downregulated the levels of StAR, P450scc and 3β-HSD, while Fancd2os knockdown reversed this effect. Fancd2os overexpression promoted ultraviolet light-induced apoptosis of TM3 cells. In contrast, Fancd2os knockdown restrained apoptosis in TM3 cells. In vivo assays revealed that higher Fancd2os levels and mouse age were associated with increased apoptosis in Leydig cells and decreased serum testosterone levels. Pearson correlation analysis exhibited a strong positivecorrelation between the expression of Fancd2os and TUNEL-positive staining in mouse testicular Leydig cells. Conclusion: Our findings suggest that Fancd2os regulates testosterone synthesis via both steroidogenic enzymes and the apoptoticpathway.
-
-
IL-35 Over-expression is Associated with Genesis of Gastric Cancer
Fan, Yong-Gang,Zhai, Jing-Ming,Wang, Wei,Feng, Bing,Yao, Guo-Liang,An, Yan-Hui,Zeng, Chao Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7
Overexpression of interleukin (IL)-35 has been found in a variety of malignancies, but the expression status in gastric cancer has yet to be elucidated clearly. In the present study, positive expression of EBI3 and p35 was 63.3% and 70.0% of cases, respectively. EBI3 expression was strongly related with larger tumor size and invasion depth (P<0.05). Similarly, expression of p35 was also correlated with larger tumor size (P<0.05). These results indicate that IL-35 might be involved in growth of gastric cancer. Interestingly, EBI3 and p35 expressions were positive correlated with Ki-67 expression. Moreover, EBI3 immunoreactivity was associated with Bcl-2 staining. Our data suggest IL-35 is correlated with genesis of gastric cancer by regulating growth and apoptosis.
-
Ding, Kun,Wang, Xiang,Zhai, Quan-Xin,Xu, Jun-Wei,Zhang, Jing-Wei,Liu, Hai-Hao The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.4
The power-voltage (P-V) curve of photovoltaic (PV) arrays connected in parallel to bypass diodes would have several local maximum power points (LMPP) under partial shading conditions (PSC). Conventional maximum power point tracking (MPPT) methods fail to search for the global maximum power point (MPP) because the searched peak point may remain at the LMPP on the P-V curve under PSC. This study proposes an improved MPPT algorithm to ensure that PV arrays operate at global maximum power point (GMPP) under PSC. The proposed algorithm is based on a critical study and a series of observations of PV characteristics under PSC. Results show the regularity of voltage interval between LMPPs. The algorithm has the advantages of rapidly reaching GMPP, maintaining stability, and recovering GMPP quickly when the operating condition changes. Simulation and experimental results demonstrate the feasibility of the proposed algorithm.
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
