http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Jianbo Chen,Enqi Wu,Hongmei Zhu,이관준,Van Men Chu,조정원,김영호,박용기,이원재,강종성 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
High-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) were used to identify five active components in the modified herbal decoction Bo-Yang-Hwan-O-Tang (mBHT), i.e., amygdalin,decursin, paeoniflorin, salvianolic acid B, and calycosin-7-O-β-D-glycoside. These components were identified by comparing their retention times and mass spectra with those of reference compounds. The conditions of both analytical methods were optimized and validated. Sufficient separation of target analytes was achieved using a buffer consisting of 40 mM sodium borate and 60 mM sodium dodecylsulfate (SDS) containing 10% methanol (pH 9.5) at 250 nm for CE analysis and gradient elution with a water-methanol mobile phase and ultraviolet (UV) photodiode array detector (DAD) at 250 nm for HPLC analysis. The mBHT components were determined within 65 min by HPLC and 16 min by CE. All calibration curves showed high linearity (R > 0.999) within the ranges tested. Intra-day and inter-day precision were less than 1.6% and 1.8% for HPLC and 2.5% and 4.8% for CE, respectively. The accuracy of the methods ranged from 98.8% to 102.3% for HPLC and from 95.9% to 108.2% for CE.
Chen, Jianbo,Yan, Xitao,Kim, Tae-Jin,Kim, Sang-Hyuck,Kim, Kyung-Tae,Lee, Young-Keun,Cho, Cheong-Weon,Baek, Jong-Suep,Park, Yong-Ki,Kim, Young-Ho,Lee, Won-Jae,Kang, Jong-Seong Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.5
The pharmacokinetics of prunasin after oral administration of amygdalin or a decoction of peach seeds was determined and compared in rats. A $C_{18}$ column was used for separation at a column temperature of $25^{\circ}C$. The mobile phase consisted of 20% aqueous acetonitrile, and the flow rate was 0.5 mL/min. After oral administration of a decoction of peach seeds, prunasin was absorbed rapidly, reaching a maximum plasma concentration ($C_{max}$) of 62.1 mg/L within 45 min. After oral administration of amygdalin, the absorption of prunasin was delayed. The $C_{max}$ of prunasin was 42.9 mg/L and was reached at 60 min. Values for the pharmacokinetic parameters of prunasin, including $T_{max}$, $C_{max}$, AUC, $T_{1/2}$, CL/F, and V1/F, were significantly different for the oral administration of amygdalin compared with that of a decoction of peach seeds.
Chen, Jianbo,Li, Meijia,Chen, Lixue,Wang, Yufang,Li, Shanshan,Zhang, Yuwei,Zhang, Lei,Song, Mingjie,Liu, Chang,Hua, Mei,Sun, Yinshi The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.1
Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.
Chen, Jianbo,Wu, Enqi,Zhu, Hongmei,Lee, Kwan-Jun,Chu, Van Men,Cho, Cheong-Weon,Kim, Young-Ho,Park, Yong-Ki,Lee, Won-Jae,Kang, Jong-Seong Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
High-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) were used to identify five active components in the modified herbal decoction Bo-Yang-Hwan-O-Tang (mBHT), i.e., amygdalin, decursin, paeoniflorin, salvianolic acid B, and calycosin-7-O-${\beta}$-D-glycoside. These components were identified by comparing their retention times and mass spectra with those of reference compounds. The conditions of both analytical methods were optimized and validated. Sufficient separation of target analytes was achieved using a buffer consisting of 40 mM sodium borate and 60 mM sodium dodecylsulfate (SDS) containing 10% methanol (pH 9.5) at 250 nm for CE analysis and gradient elution with a water-methanol mobile phase and ultraviolet (UV) photodiode array detector (DAD) at 250 nm for HPLC analysis. The mBHT components were determined within 65 min by HPLC and 16 min by CE. All calibration curves showed high linearity (R > 0.999) within the ranges tested. Intra-day and inter-day precision were less than 1.6% and 1.8% for HPLC and 2.5% and 4.8% for CE, respectively. The accuracy of the methods ranged from 98.8% to 102.3% for HPLC and from 95.9% to 108.2% for CE.
Jianbo Ji,Wen Chen,Shanlin Sun 한국통신학회 2013 Journal of communications and networks Vol.15 No.6
In this paper, we investigate the capacity of a multipointto-point cognitive radio network. In existing works, the asymptoticcapacity is only obtained in the high peak power region at secondarytransmitter (ST) or obtained without considering the interferencefrom primary transmitter (PT) for easy analysis. Here, weanalyze the asymptotic capacity by considering an arbitrary peakpower at the ST and the interference from the PT based on extremevalue theory. Simulation results show that our approximatedcapacity is well-matched to the exact capacity. Furthermore, thescaling law of our capacity is found to be double logarithm of thenumber of secondary users.
Next Location Prediction with a Graph Convolutional Network Based on a Seq2seq Framework
( Jianwei Chen ),( Jianbo Li ),( Manzoor Ahmed ),( Junjie Pang ),( Minchao Lu ),( Xiufang Sun ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.5
Predicting human mobility has always been an important task in Location-based Social Network. Previous efforts fail to capture spatial dependence effectively, mainly reflected in weakening the location topology information. In this paper, we propose a neural network-based method which can capture spatial-temporal dependence to predict the next location of a person. Specifically, we involve a graph convolutional network (GCN) based on a seq2seq framework to capture the location topology information and temporal dependence, respectively. The encoder of the seq2seq framework first generates the hidden state and cell state of the historical trajectories. The GCN is then used to generate graph embeddings of the location topology graph. Finally, we predict future trajectories by aggregated temporal dependence and graph embeddings in the decoder. For evaluation, we leverage two real-world datasets, Foursquare and Gowalla. The experimental results demonstrate that our model has a better performance than the compared models.
Ji, Jianbo,Chen, Wen,Sun, Shanlin The Korea Institute of Information and Commucation 2013 Journal of communications and networks Vol.15 No.6
In this paper, we investigate the capacity of a multipoint-to-point cognitive radio network. In existing works, the asymptotic capacity is only obtained in the high peak power region at secondary transmitter (ST) or obtained without considering the interference from primary transmitter (PT) for easy analysis. Here, we analyze the asymptotic capacity by considering an arbitrary peak power at the ST and the interference from the PT based on extreme value theory. Simulation results show that our approximated capacity is well-matched to the exact capacity. Furthermore, the scaling law of our capacity is found to be double logarithm of the number of secondary users.
Zhuoyuan Chen,Jianbo Zhao,Peiyang Li,Aizhong Qin,Zhihua Gao,Wenfen Zhao,Shaocan Wang,Guanfeng Lia 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.1
In this work, the fabrication and improvement of a lightweight and corrosion-resistant polyurethane (PU) based polymerconcrete are studied. The aggregate in traditional polymer concrete is generally crushed stone. Due to the low bonding strengthbetween polymer matrix and crushed stone, it is easy to fall off between polymer matrix and crushed stone after long-termuse, resulting in the degradation of the performance of polymer concrete. In order to overcome the low bond strength betweencrushed stone and polymer matrix in polymer concrete, modified polyetheramine particles were used to enhance the finalmechanical parameters of PU based polymer concrete. A series of mechanical and environmental tests were carried out, andthe effects of aggregates addition ratio and type on the mechanical properties of polymer concrete were analyzed. Theexperimental results determined the influence mechanism of aggregates proportion and type on the mechanical properties ofpolymer concrete, and obtained the appropriate aggregates type and addition proportion. The current work reveals that usingmodified polyetheramine particles as aggregates of polymer concrete can significantly enhance the bond strength anddurability between polymer matrix and aggregates. The density of this polymer concrete proposed in this paper is about 1.2g/mm3; The density of traditional polymer concrete is about 1.5-1.8 g/mm3, the weight can be reduced by 25%, and there isno problem of falling off between polymer matrix and aggregate.
Seismic Performance Evaluation of the Highway N High-Voltage Substation
Dongming Yan,Jianbo Li,Genda Chen 한국강구조학회 2015 International Journal of Steel Structures Vol.15 No.1
In this study, the Highway N Substation in Missouri was studied with finite element method for its vulnerability underseismic loading. The component of the substation system was modeled with due considerations of mass, stiffness andgeometries. Full-scale shake table experiments were carried out on three electric switches to partially validate the finite elementmodel (FEM). After a systematical modal analysis based on the FEM, response spectrum analyses were performed tocharacterize the dynamic behavior of ‘rigid’ buses and switches of the structure. In time-history analysis, two methods wereemployed to generate the seismic motions: 1) site-specific synthetic ground motion and 2) spectrum compatible ground motion. The results from both ground motions were analyzed and the magnitude and location of the maximum moments in each casewere identified. The effect of slip joints on switches was examined and the maximum relative displacement under the seismicloads was identified.