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Tian, Shu-Bo,Yu, Jian-Chun,Kang, Wei-Ming,Ma, Zhi-Qiang,Ye, Xin,Cao, Zhan-Jiang,Yan, Chao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Our aim was to investigate the value of combined detection of serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA 242 and CA 50 in diagnosis and assessment of prognosis in consecutive gastric cancer patients. Clinical data including preoperative serum CEA, CA 19-9, CA 242, and CA 50 values and information on clinical pathological factors were collected and analyzed retrospectively. Univariate and multivariate survival analyses were used to explore the relationship between tumor markers and survival. Positive rates of tumor markers CEA, CA 19-9, CA 242 and CA 50 in the diagnosis of gastric cancer were 17.7, 17.1, 20.4 and 13.8%, respectively, and the positive rate for all four markers combined was 36.6%. Patients with elevated preoperative serum concentrations of CEA, CA 19-9, CA 242 and CA 50, had late clinical tumor stage and significantly poorer overall survival. Five-year survival rates in patients with elevated CEA, CA 19-9, CA 242 and CA 50 were 28.1, 25.8, 27.0 and 24.1%, respectively, compared with 55.0, 55.4, 56.4 and 54.5% in patients with these markers at normal levels (p<0.01). In multivariate Cox proportional hazards analyses, an elevated CA 242 level was determined to be an independent prognostic marker in gastric cancer patients. Combined detection of four tumor markers increased the positive rate for gastric cancer diagnosis. CA 242 showed higher diagnostic value and CA 50 showed lower diagnostic value. In resectable gastric carcinoma, preoperative CA 242 level was associated with disease stage, and was found to be a significant independent prognostic marker in gastric cancer patients.
Aging Hardening and Precipitation Characteristics of Extruded Mg–9Al–0.8Zn–0.2Mn–0.3Ca–0.2Y Alloy
Fangce Liu,Yue Bi,Chao Wang,Jian Kang,Tong He,Yandong Liu,Guo Yuan 대한금속ᆞ재료학회 2023 METALS AND MATERIALS International Vol.29 No.2
In this paper, high temperature hot rolling and weld simulations were performed in Al-killed and Ti-Zr-killed steels. Themicrostructure and impact toughness of the heat-affected zone (HAZ) of the two experimental steels were investigated, andthe ferrite transformation behavior in HAZ was also observed. The characteristic inclusions in the Ti-Zr-killed steel werestudied using electron probe microanalysis (EPMA) and electron backscatter diffraction (EBSD). The results suggested thatthe HAZ microstructure of the Al-killed steel consisted of coarse bainite ferrite (BF) and granular bainite (GB) packets. TheHAZ microstructure of Ti-Zr-killed steel was significantly refined and mainly contained fine acicular ferrite (AF) and BF. TheTi-Zr-O + MnS inclusions were 0.3–2.1 μm and could effectively promote the formation of AF after the weld simulations. MnS had a specific orientation relationship: {111}MnS║{0001}Ti-Zr-O, < 110 > MnS║ < 2 −1−1 0 > Ti-Zr-O with Ti-Zr-O inclusion,and its precipitation promoted the formation of the Mn-depleted zone (MDZ). AF formed around it. The formation of aninterlocked AF structure in the HAZ of the Ti-Zr-killed steel obviously increased the proportion of high angle grain boundaries(HAGBs) and refined the average effective grain size of the HAZ microstructure. Consequently, the impact toughnessof the Ti-Zr-killed steel had no deterioration, but the impact toughness of Al-killed steel had an obvious loss after the weldsimulation with a heat input of 70 kJ/cm. The impact absorption energy of HAZ of Ti-Zr-killed steel was improved from 6to 219 J compared to Al-killed steel.
Fangce Liu,Yue Bi,Chao Wang,Jian Kang,Tong He,Yandong Liu,Guo Yuan 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.3
In this paper, high temperature hot rolling and weld simulations were performed in Al-killed and Ti-Zr-killed steels. Themicrostructure and impact toughness of the heat-affected zone (HAZ) of the two experimental steels were investigated, andthe ferrite transformation behavior in HAZ was also observed. The characteristic inclusions in the Ti-Zr-killed steel werestudied using electron probe microanalysis (EPMA) and electron backscatter diffraction (EBSD). The results suggested thatthe HAZ microstructure of the Al-killed steel consisted of coarse bainite ferrite (BF) and granular bainite (GB) packets. TheHAZ microstructure of Ti-Zr-killed steel was significantly refined and mainly contained fine acicular ferrite (AF) and BF. TheTi-Zr-O + MnS inclusions were 0.3–2.1 μm and could effectively promote the formation of AF after the weld simulations. MnS had a specific orientation relationship: {111}MnS║{0001}Ti-Zr-O, < 110 > MnS║ < 2 −1−1 0 > Ti-Zr-O with Ti-Zr-O inclusion,and its precipitation promoted the formation of the Mn-depleted zone (MDZ). AF formed around it. The formation of aninterlocked AF structure in the HAZ of the Ti-Zr-killed steel obviously increased the proportion of high angle grain boundaries(HAGBs) and refined the average effective grain size of the HAZ microstructure. Consequently, the impact toughnessof the Ti-Zr-killed steel had no deterioration, but the impact toughness of Al-killed steel had an obvious loss after the weldsimulation with a heat input of 70 kJ/cm. The impact absorption energy of HAZ of Ti-Zr-killed steel was improved from 6to 219 J compared to Al-killed steel.
Sexuality and Quality of Life in Eastern Taiwan People With Schizophrenia
Mei Hua Chung,Jian-Kang Chao,Mi Chia Ma,Ru Wei Lin 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.1
Objective Patients with schizophrenia are living at the border of society and their sexuality is often neglected. The aim of the study is to explore the association among The Brief Psychiatric Rating Scale (BPRS), quality of life (QoL), Taiwanese Depression Questionnaire, and Sexual Desire Inventory in people with schizophrenia (PwS). Methods This study used a cross-sectional design with 277 psychiatric inpatients. A descriptive analysis, difference analysis, and logistic regression model were presented to identify relevant variables that may affect the probability of good QoL. Results The study showed that male PwS had higher scores of standard deviation (SD) than females in PwS. The study also showed that smoking, early illness onset age, and shorter illness duration demonstrated a significantly higher SD. The logistic regression analysis showed that BPRS, depression, and SD significantly affected the probability of QoL. By structural equation model, SD would be positively correlated with mental status and SD would indirectly influence QoL. Conclusion Our results showed psychological and sociological factors interactions may contribute to the QoL and SD for PwS. This study also demonstrated a close relationship between SD, depression, and BPRS. These factors may predict the probability of good life quality for the PwS.