Latin Hypercube Sampling Based Probabilistic Small Signal Stability Analysis Considering Load Correlation

Jian Zuo,Yinhong Li,Defu Cai,Dongyuan Shi 대한전기학회 2014 Journal of Electrical Engineering & Technology Vol.9 No.6

A novel probabilistic small signal stability analysis (PSSSA) method considering load correlation is proposed in this paper. The superiority Latin hypercube sampling (LHS) technique combined with Monte Carlo simulation (MCS) is utilized to investigate the probabilistic small signal stability of power system in presence of load correlation. LHS helps to reduce the sampling size, meanwhile guarantees the accuracy and robustness of the solutions. The correlation coefficient matrix is adopted to represent the correlations between loads. Simulation results of the two-area, four-machine system prove that the proposed method is an efficient and robust sampling method. Simulation results of the 16-machine, 68-bus test system indicate that load correlation has a significant impact on the probabilistic analysis result of the critical oscillation mode under a certain degree of load uncertainty.

Latin Hypercube Sampling Based Probabilistic Small Signal Stability Analysis Considering Load Correlation

Zuo, Jian,Li, Yinhong,Cai, Defu,Shi, Dongyuan The Korean Institute of Electrical Engineers 2014 Journal of Electrical Engineering & Technology Vol.9 No.6

A novel probabilistic small signal stability analysis (PSSSA) method considering load correlation is proposed in this paper. The superiority Latin hypercube sampling (LHS) technique combined with Monte Carlo simulation (MCS) is utilized to investigate the probabilistic small signal stability of power system in presence of load correlation. LHS helps to reduce the sampling size, meanwhile guarantees the accuracy and robustness of the solutions. The correlation coefficient matrix is adopted to represent the correlations between loads. Simulation results of the two-area, four-machine system prove that the proposed method is an efficient and robust sampling method. Simulation results of the 16-machine, 68-bus test system indicate that load correlation has a significant impact on the probabilistic analysis result of the critical oscillation mode under a certain degree of load uncertainty.

제6회 한,중 형법 국제 학술심포지움 : 미성년범에게 무기징역을 적용할 수 있는지 여부를 논함

좌견위 ( Jian Wei Zuo ) 한국비교형사법학회 2008 비교형사법연구 Vol.10 No.2

Structure and electrical properties of Pr6O11-doped CaCu3Ti4O12 NTC ceramics

Zuo Yang,Tian Jian,Tian Yuxin,Miao Guangtan,Fu Peng 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.3

The xPr6O11–(1 − x)CaCu3Ti4O12 (CCTO) ceramics with perovskite structure were prepared by the solid-state reaction method. The effects of Pr 6O11 addition on the microstructure and electrical properties of the CCTO ceramics were studied. The addition of Pr 6O11 promoted the sintering of CCTO ceramics, and the mean grain sizes increased gradually from 2.13 to 5.08 μm with increasing Pr 6O11 content. All the samples had noticeable negative temperature coefficient (NTC) effect, and both the grain and grain boundary effects contributed to their NTC characteristics. The thermistor characteristic parameter B25/75 decreased from 6883 to 5291 K as Pr 6O11 contents increased from 0.00 to 0.08. The analysis shows that the conductivity of Pr 6O11–CCTO ceramics arises mainly from the electron hopping transport mechanism. The GB resistances are noticeably higher than grain resistances at the same Pr 6O11 content. All the samples showed electrical relaxation behavior. The above observations indicate that the structures and electrical properties of CCTO ceramics can be attuned precisely by adjusting the Pr 6O11 concentration.

Anti-Tumor Effect of a Novel DOX/GA-CdTe QD was Mediated by Apoptotic and Autophagic Cell Death

Huaqin Zuo,Fan Wang,Di Zhou,Yi Zhou,Bing Chen,Jian Ouyang,Peipei Xu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.1

Burkitt's lymphoma is a highly proliferative B-cell malignancy characterized by MYC oncogene translocation. Intensive short-cycle chemotherapy could effectively improve the outcome of this disease. However, drug resistance limits the treatment of refractory/relapsed disease. Thus, we constructed and investigated a novel cadmium–tellurium quantum dot conjugated with doxorubicin and gambogic acid (DOX/GA-CdTe QDs) for cancer cell combined treatment in Raji, a Burkitt's lymphoma cell line. Results showed that DOX/GA-CdTe QDs could significantly improve anti-tumor effects compared with drugs alone in the Raji cell line. Flow cytometry, transmission electron micrographs and overexpression of Beclin1 and LC3 II/I showed that apoptosis and autophagy were involved in the process. However, DOX/GA-CdTe QDs did not cause cell cycle arrest, whereas DOX alone or combined with GA could cause apparent G2/M phase arrest. Hence, the novel DOX/GA-CdTe QDs offer a promising approach of drug delivery into cancer cells.

A component mode synthesis method for 3-D finite element models of aero-engines

Yanfei Zuo,Jian-jun Wang 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.12

Because of the complicated configuration of aero-engines, 3-D finite element models are convenient and accurate to to simulate the vibrationperformance of the aero-engines, and are now widely used with a high order of Degrees of freedom (DOFs). A Component modesynthesis (CMS) method is introduced to reduce the computational effort of rotors and stator modeled by 3-D finite element. By additionalmaster DOFs in substructures it’s more convenient than traditional CMS to get the inner response of substructures without modeexpansion and is validated as being as accurate as traditional CMS. Rotating substructure of rotors with variable spinning speed can alsobe reduced by the method. Reduced gyroscopic matrix depended by variable spinning speed can be easily obtained by multiplying aspeed coefficient to unit condensed gyroscopic matrix. A reduction example of an aero-engine model including casing model, bearingsand counter-rotating rotors shows the accuracy and efficiency of the method. The method greatly decreases RAM and solution time usedfor dynamic analysis, which brings possibilities of a great number of repeatability analyses.

Stigmast-4-en-6β-ol-3-one decreases viability and induces apoptosis and ferroptosis in liver cancer cells by reducing E2F1

Zhiyun Zhang,Jian Wang,Weiping Wan,Zhengchao Shen,Aixue Zuo,Rong Chen,Qinyi Wu,Enli Cai,Feng Huang,Rongping Zhang,Xinan Shi 한국통합생물학회 2023 Animal cells and systems Vol.27 No.1

Hepatocellular carcinoma (HCC) is a frequently occurring malignant gastrointestinal cancer. The 5-year survival rate of HCC is still below 8%, and thus, identifying more effective therapeutic methodsis needed. Here, we evaluated the effects of Stigmast-4-en-6β-ol-3-one (S463) on the viability andcolony formation of liver cancer cells. S463 treatment decreased the viability and inducedapoptosis and ferroptosis in liver cancer cells, and also increased cellular malondialdehyde(MDA) and lipid peroxidation levels. In S463 treated cells, the expression level of Bax wasincreased, and the expression level of GPX4 was reduced, and the cleavage of PARP wasimproved. We also found that S463 treatment downregulated E2F1 and upregulated p53 atboth the mRNA and protein levels. Importantly, rescue experiments revealed thatoverexpression of E2F1 partially restored S463-induced Bax and p53 upregulation and GPX4downregulation and counteracted the S463-induced decrease in cell viability and colonyformation and the S463-induced increase in MDA and lipid peroxidation levels. Our findingssuggest that S463 significantly inhibits viability and colony formation and induces apoptosisand ferroptosis in liver cancer cells via E2F1.

Simulation analysis and evaluation of decontamination effect of different abrasive jet process parameters on radioactively contaminated metal

Zhong Lin,Deng Jian,Zuo Zhe-wen,Huang Can-yu,Chen Bo,Lei Lin,Lei Ze-yong,Lei Jie-heng,Zhao Mu,Hua Yun-fei 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.11

A new method of numerical simulating prediction and decontamination effect evaluation for abrasive jet decontamination to radioactively contaminated metal is proposed. Based on the Computational Fluid Dynamics and Discrete Element Model (CFD-DEM) coupled simulation model, the motion patterns and distribution of abrasives can be predicted, and the decontamination effect can be evaluated by image processing and recognition technology. The impact of three key parameters (impact distance, inlet pressure, abrasive mass flow rate) on the decontamination effect is revealed. Moreover, here are experiments of reliability verification to decontamination effect and numerical simulation methods that has been conducted. The results show that: 60Co and other homogeneous solid solution radioactive pollutants can be removed by abrasive jet, and the average removal rate of Co exceeds 80%. It is reliable for the proposed numerical simulation and evaluation method because of the well goodness of fit between predicted value and actual values: The predicted values and actual values of the abrasive distribution diameter are Ф57 and Ф55; the total coverage rate is 26.42% and 23.50%; the average impact velocity is 81.73 m/s and 78.00 m/s. Further analysis shows that the impact distance has a significant impact on the distribution of abrasive particles on the target surface, the coverage rate of the core area increases at first, and then decreases with the increase of the impact distance of the nozzle, which reach a maximum of 14.44% at 300 mm. It is recommended to set the impact distance around 300 mm, because at this time the core area coverage of the abrasive is the largest and the impact velocity is stable at the highest speed of 81.94 m/s. The impact of the nozzle inlet pressure on the decontamination effect mainly affects the impact kinetic energy of the abrasive and has little impact on the distribution. The greater the inlet pressure, the greater the impact kinetic energy, and the stronger the decontamination ability of the abrasive. But in return, the energy consumption is higher, too. For the decontamination of radioactively contaminated metals, it is recommended to set the inlet pressure of the nozzle at around 0.6 MPa. Because most of the Co elements can be removed under this pressure. Increasing the mass and flow of abrasives appropriately can enhance the decontamination effectiveness. The total mass of abrasives per unit decontamination area is suggested to be 50 g because the core area coverage rate of the abrasive is relatively large under this condition; and the nozzle wear extent is acceptable

Case-control Study of Single Nucleotide Polymorphisms of PSCA and MUC1 Genes with Gastric Cancer in a Chinese

Li, Fang,Zhong, Mei-Zuo,Li, Jian-Huang,Liu, Wei,Li, Bin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

Aims: A case-control study of 300 gastric cancer patients and 300 controls was conducted to investigate whether the polymorphisms rs2294008 in PSCA and rs2070803 in MUC1 might be associated with risk of gastric cancer in a Chinese population. Methods: Single nucleotide polymorphisms (SNPs) were genotyped using the Sequenom MassARRAY platform. Results: The data showed that the rs2294008 TT genotype increased gastric cancer risk to an adjusted odds ratio (OR) of 2.26 (95%CI 1.25-4.07), TC to 1.72 (95%CI 1.23-2.42) and TC/TT to 1.81 (95% CI 1.31-2.50), while the rs2070803 GA genotype was associated with a decrease in risk to an adjusted OR of 0.42 (95% CI 0.28-0.62) and rs2070803 GA / AA to 0.46 (95% CI 0.32-0.67). Further stratification analysis revealed that rs2294008 in PSCA consistently increased risk of both intestinal and diffuse-type gastric cancers. The effect of rs2070803 in MUC1 was noteworthily also consistent with both subtypes. Conclusions: Our study suggested rs2294008 in the PSCA gene to be associated with increased risk of gastric cancer and rs2070803 in MUC1 to play a protective role in a Chinese population.

Apoptin Induces Apoptosis in Human Bladder Cancer EJ and BIU-87 Cells

Zhan, Hui,Wang, Jian-Song,Wang, Hai-Feng,Zuo, Yi-Gang,Wang, Chun-Hui,Ding, Ming-Xia Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

Objective: To investigate whether apoptin is a apoptosis-inducing protein with a potential for bladder cancer therapy. Methods: We constructed a PCDNA3/Apoptin eukaryotic expression vector, and transfected this vector into bladder cancer cell lines BIU-87 and EJ, then observed the results by RT-PCR, transmission electron microscopy, MTT assay and the flow cytometry (TUNEL method). Results: PCDNA3/Apoptin successfully induced a high level apoptosis in both bladder cancer cell lines, compared with the controls (p<0.05). Conclusions: Apoptin can induce high level apoptosis in human bladder cancer EJ and BIU-87 cells, which suggests a potential for human bladder cancer therapy.