Modulation of Gene Expressions and Enzyme Activities of Methionine Sulfoxide Reductases by Cold, Aba or High Salt Treatments in Arabidopsis

Oh, Jee-Eun,Hong, Suk-Whan,Lee, Yunsook,Koh, Eun-Ji,Kim, Kideok,Seo, Youngwon,Chung, Namhyun,Jeong, Moonsoo,Chang,Chang, Cheolseong,Lee, Byoungcheon,Kim, Kyoung Heon,Lee, Kwangwon,Lee, Hojoung 생명자원연구 2005 생명자원연구 Vol.13 No.-

The Beneficial Effect of Adenophorae Radix on DSS‐induced Colitis in Mice

Ji?Wook Jung,Sa?Rang Oh,Eun?Mi Ahn,Eun?Ju Yang,Su?Jin Kim 대한의생명과학회 2013 Biomedical Science Letters Vol.19 No.3

Ulcerative colitis (UC) is an inflammatory bowel disease, which is a chronic gastrointestinal disorder. Adenophorae Radix (AR) has been used as a traditional medicine for various diseases including strengthening cardiac function, allaying a fever, and easing pain and cough. However, the regulatory effects of AR in intestinal inflammation are not yet understood. This study attempted to determine the effect of AR in dextran sulfate sodium (DSS) ? induced colitis in mice. The colitis mice were induced by drinking water containing 5% DSS for 7 days. The results showed that mice treated with DSS showed remarkable clinical signs, including weight loss, and reduced colon length. Administration of AR attenuated weight loss, colon shortening and inhibited the levels of interleukin (IL) ? 6 in DSS ? treated colon tissues. These results provide experimental evidence that AR might be a useful therapeutic medicine for patients with UC.

The form and function of Inversion in Discourse

( Oh¸ Ji Yung ) 현대영미어문학회 2009 현대영미어문학회 추계학술대회 발표논문집 Vol.2009 No.-

Fine mapping of grain weight QTL, tgw11 using near isogenic lines from a cross between Oryza sativa and O. grandiglumis

Ji‐Min Oh,Sangshetty Balkunde,Paul Yang,Dong‐Beom Yoon,안상낙 한국유전학회 2011 Genes & Genomics Vol.33 No.3

In our previous study, we reported the grain weight (GW)QTL, tgw11 in isogenic lines derived from a cross between Oryza sativa ssp. Japonica cv. Hwaseong and O. grandiglumis. The O. grandiglumis allele at tgw11 decreased GW in the Hwaseong background. To fine-map tgw11, one F5 plant homozygous for the O. grandiglumis DNA in the target region on chromosome 11 was selected from F_4 line,CR1242 segregating for tgw11 and crossed with Hwaseong to produce secondary F_2 and F_3 populations. QTL analysis using 760 F_2 plants confirmed the existence of tgw11 with an R^2 value of 15.0%. This QTL explained 32.2% of the phenotypic variance for GW in 91 F_3 lines. Substitution mapping with 65 F_3 lines with informative recombination breakpoints in the target region was carried out to narrow down the position of the tgw11. The result indicated that tgw11 was located in the 900-kb interval between two SSR markers, RM224 and RM27358. QTLs for grain width and grain thickness were also located in the same interval suggesting that a single gene is involved in controlling these three traits. Analysis of F3 lines indicated that the variation in TGW is associated with variation in grain shape, specifically grain thickness and grain width. Genetic analysis indicated that the O. grandiglumis allele for small seed was dominant over the Hwaseong allele. SSR markers tightly linked to the GW QTL would be useful in marker-assisted selection for variation in GW in breeding program.

백련결사 보현도량의 의미에 관한 고찰

오지연(Oh, ji-yeon) 불교학연구회 2012 불교학연구 Vol.33 No.-

백련결사와 정혜결사는 한국불교사에서 대표적인 두 결사이다. 정혜결사의 뜻은 간화(看話)의 선맥을 통해서 지금까지도 계승되어 오고 있지만, 법화예참도량이었던 백련결사의 취지는 오늘날 찾아보기가 힘들다. 원묘의 비문에서는, 우리나라에 불교가 전래된 이래로 보현도량을 열어서 널리 선관[禪]과 송경[誦]을 행하도록 권한 것은 처음이었다고 한다. 백련사의 보현도량은 근본적으로 법화 일불승(一佛乘)의 뜻을 천명하며 그것을 실현하고자 한 도량이었다. 그것을 네 측면으로 말하면, 삼승의 가르침들을 묘법(妙法)으로 회통해내는 교일(敎一), 송경(誦經)과 선정 등의 여러 수행법들이 모두 한결같이 성불도(成佛道)라고 하는 행일(行一), 모든 사람이 신분차이나 남녀노소에 관계없이 모두 부처와 다름없다고 인식하는 인일(人一), 사(事)법과 이(理)법이 둘이 아니라고 깨닫는 이일(理一) 등의 네 가지 일승[四一]을 그대로 실현하고자 한 도량이었다고 할 수 있다. There have been two famous and important Buddhist practice communities in Korean dynasties, one was the practice community of the Meditation and wisdom (定慧結社) by Ji-nul (知訥), the other was the practice community of White Lotus (白蓮結社) by Yo-sae (了世). Even if the point of the former still exists through Koan meditation, the purpose of the latter which was the gathering of the repentance method of the Lotus Samadhi would be hard to find these days. The epitaph of Yo-sae, the first president of the community of White Lotus, says: ‘It was the first time to recommend dhyāna-contemplation (禪觀) and reciting sūtras (誦經) to the public through opening the practicing site of Samantabhadra since the introduction of Buddhism in Korea.’ In essence, the community of White Lotus was the meeting to clarify and actualize the essential of the One Vehicle in Lotus sutra. Again in four aspects, the four ones [四一]: the first, to unite the three other teachings in one subtle dharma is called ‘the teaching of one vehicle (敎一)’, the second, including many other practices like recitation or meditation are one and the same way to the ultimate enlightenment called ‘the sole Buddha procedure (行一)’, the third, the thinking that everybody regardless of sex, age or class is none other than Buddha is called ‘men all and only as Buddha (人一)’, the fourth, the understanding that Noumenon and phenomena are non-dual is called ‘one ultimate truth of the reality of all existence (理一)’.

捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響

Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.

유방암의 위와 대장전이

유현아,김은영,서민지,정은,조민정,오현진,장지혜,박지찬,이정의,박석영 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2

Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.

방사선치료를 받은 후두암 환자의 특성 및 치료 결과

오윤경,장지영,도남용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Pmpose: To present the characteristics and treatment outcome of laryngeal cancer patients who were treated by radiation therapy with or without surgery and chemotherapy. Materials and Melhods: A total of 23 patients with laryngeal cancer treated from 1998 through 2003 were available for analysis. The primary site of the cancer was the glottis in 12 patients, the supraglottis in 10 patients, and the subglottis in 1 patient. The stages were Ⅰ in 7 patients (30%), Ⅱ in 5(22%), Ⅲ in 3(13%), IV in 6(26%), and recurrent in 2(9%). The minimum follow-up period in surviving patients is 3 years after the radiation therapy. They were treated by radiation therapy at least 44 Gy with or without surgery and chemotherapy. Results: The overall survival at 1, 2, 3, 5 years in total patients were 95.6%, 82.6%, 78.2%, 73.9%. The overall survival at 1, 2, 3, 5 years in the glottic cancer patients were 100%, 100%, 91.6%, 91.6%. The overall survival at 1, 2, 3, 5 years in the supraglottic cancer patients were 90%, 70%, 70%, 60%. The 3-year overall survival showed the significant difference according to the primary site (glottic vs. supraglottic), cervical lymph node status (negative vs. positive), and overall time of radiation therapy (<50 days vs. 50-59 days vs. ≥60 days), Conclusion: The overall survival rate of laryngeal cancer patients in this analysis seems to be similar in early glottic cancers and relatively good in supraglottic cancers as compared with the results of other studies even though the total number of patients is small.

한국판 Neuropsychiatric Inventory로 본 치매 단계에 따른 행동ㆍ정신증상 특징

오병훈,차경렬,홍창형,김지혜 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : This study aimed to compare the behavioral psychological symptoms of dementia by stages and to suggest the proper management treatment plan. Methods : We examined behaviral psychological symptoms in 17 dementia patients with mild stage (CDR=0.5, 1), 18 de-mentia patients with moderate stage (CDR=2) and 24 dementia patients with severe stage (CDR=3, 4). We compared the prevalence and the composite scores (frequency x seventy) of each behavioral domain in K-NPI among three groups. The MMSE-K, GDS, Barthel ADL were also administrated to evaluate the general cognitive function, seventy of the patients and activity of daily living. Results : The most common behavioral disturbances were apathy/indifference, depression/dysphoria, and aberrant motor behavior. The mean composite score of aberrant motor behavior increased by stages of dementia severity with statistical significance. The total score of the K-NPI increased with severer stages of dementia the result didn't show statistical significance. The K-NPI score showed the positive correlation with CDR, GDS and the negative correlation with MMSE-K, B-ADL. But, there was no statistically significant correlation. Conclusion : Behavioral and Psychological Symptoms of Dementia (BPSD) change by the stages of dementia. The practical guideline for BPSD management according to dementia stage is needed. Re-evaluation and new therapeutic inter-vention must be considered by the stages of dementia.

선수계약의 불이행과 손해배상책임액의 확정 : 대법원 2004. 6. 24. 선고 2002다 6951, 6968 판결을 중심으로

오지상 이화여자대학교 법학전문대학원 2011 Ewha Law Review Vol.1 No.2

대상판결은 피고인 프로축구 선수가 원고인 프로축구구단과 입단계약을 체결하면서 차후 해외진출 후 국내로 귀국 시에는 원고 구단으로 복귀하겠다는 약정을 체결한 뒤에 이를 위반한 경우, 해당 약정의 법적 성격과 그 손해배상의 산정방법이 문제가 된 사안이다. 원심과 대상판결은 피고와 원고 사이의 복귀약정의 성격을 원고 축구단에 복귀하기 위해 ‘성실하게 교섭에 응할 의무’를 부담 하는 것이라고 해석하여 피고의 채무불이행 책임을 인정하였다. 다만 그 손해배상액의 확정에 관해서는 원심과 대상판결이 의견을 달리한다. 원심은, 원고에게 발생한 손해액을 구체적으로 산정하기 어려우므로 위자료의 보완적 기능을 빌어 위자료의 지급으로서 원고의 손해를 전보케 함에 반하여, 대법원은 손해와 관련된 모든 간접사실들을 종합하여 손해의 범위인 수액을 구체적으로 확정하여야 한다고 한다. 이 글에서는 원고와 피고 사이의 이적료 약정을 복귀의 대가인 동시에 입단조건이라는 이중적 성격으로 파악한 판결 이유의 타당성을 살펴본 후, 손해배상의 범위를 확정하는 것이 곤란한 경우 그 배상액의 증명에 관해 본 판결이 밝힌 법리에 대하여 검토해 보고자 한다. The present case at the Supreme Court deals with a breach of an agreement between a football club owner, the complainant, and a professional football play, the defendant. The agreement stipulated that the defendant should return to the football club of the complainant from a football club overseas, and the legal characteristics of the agreement and the methods of estimation of the damages from the defendant’s breach of such agreement are at dispute. Both the original trial court and the Supreme Court construed the characteristics of the returning agreement between the defendant and the complainant as charging the defendant with default responsibility to return to the football club of the complainant as "an obligation of sincerely responding to the negotiation." Nevertheless, the original trial court and the Supreme Court disagree with the determination of the damages. The original trial court decided that, since the amount of the damages is difficult to be specifically estimated and compensation money serves complementary functions, compensation money should be awarded to the complainant in order to supplement the damages whereas, the Supreme Court ruled that all evidentiary facts related to the damagesshould be comprehensively combined to specifically estimate the range and amount of the damages. In this article, the ratio decidendi of the Supreme Court (i.e. a transfer fee agreement between the complainant and the defendant is understood has dual characteristics:both a reward for returning and a condition to enter the club) is examined. Afterwards, principle of law clarified by such ruling concerning the confirmation of compensation money when the determination of damage compensation range is difficult shall be reviewed.