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        수완진동 증후군에서 신경장해의 조기진단을 위한 객관화된 방법

        윤재국,이헌,최나리,김석환,박형욱,이지호,유철인 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

        목적: 통각과 진동감각 역치검사 및 수부와 수지의 악력, 그리고 수지의 운동기능검사(태평) 등과 근로자들이 호소했던 증상에 대한 HAVS의 스톡홀름 워크샵 분류와의 관련성을 통해 좀 더 객관화된 신경학적 조기검사 방법을 찾고 타당성을 검증하고자 하였다. 방법: 2000년 1월부터 2007년 12월까지 수부진동에 폭로되고 수부의 불편함을 호소하여 진동 장해에 대한 검사를 시행한 497명의 근로자를 대상으로 하였다. 일차적으로 문진을 통해 직업력에 대해 알아보고 과거력을 조사했다. 대상자들의 스톡홀름 워크샵 분류에 따른 소견을 확인하고 수부의 말초 순환기능 검사(손톱압박, 수지피부 온도), 신경기능 검사(통각과 진동각 역치), 운동기능 검사(악력, 태평) 등을 시행하였다. 다른 질환의 감별을 위한 몇 가지 이학적 검사를 실시하고 스톡홀름 워크샵 분류에 따른 검사 결과들을 분석하였다. 결과: 사용 도구는 그라인더 단독 사용이 265명 (67.3%)으로 가장 많았으며 평균 노출 연수는 14.8년이었다. 통각과 진동감각에서 스톡홀름 워크샵 분류 단계에 따른 역치가 증가하는 경향을 보였으나 통각은 양측 모두 통계적인 유의성이 없었고, 진동감각은 125와 250 Hz에서 양측 모두 유의했다(p=0.006-0.038). 수부와 수지의 악력은 단계가 올라갈수록 감소하는 경향을 보였지만 수부와 수지 모두 우측에서만 통계적으로 유의했다 (p=0.041, p<0.01, p=0.034). 태평 첫수는 단계가 올라 가면서 전반적으로 태핑 첫수가 감소하였으며 좌측에서만 통계적으로 유의했다(p=0.002-0.019). 결론: 본 연구는 수부 진동 노출자들의 수부 불편함에 대한 신경계통을 초기에 정량적으로 객관화하여 진단할 수 있는 단일 방법은 아직 없으며 일상생활의 불편함과 스톡홀름 워크샵 분류 등을 통한 주관적인 증상에 더하여 수지 통각과 진동감각 역치검사, 수부와 수지 악력검사, 운동기능검사(태핑) 등을 통합하면 초기에 객관적으로 진단하는 것이 가능할 것으로 판단된다. Objectives: In order to determine find out the best methods for a more objective detection of neurologic abnormality in early hand ann vibration syndrome(HAVS), early with analyzing the validity of each of the detection methods was analyzed. We evaluated the relationships between the sensorineural stage of Stockholm-revised vibration syndrome classification and the results of several tests. Methods: 497 workers were investigated for symptom, exposure duration, the types of tools used, and medical history from January 2000 to December 2007. Pain sense threshold, vibrotactile threshold, hand grasp force, finger grasp force, and a finger tapping frequency test were performed by the workers. Results: The grinder(67.3%) was the most commonly used tool and the mean exposure duration was 14.8 years. Although the pain sense and vibrotactile threshold level tended to increase according to sensorineural stage of the Stockholm classification, there was statistically significant difference in the vibrotactile threshold of 125, 250 Hz (P=0.006~0.038) but not in the pain sense threshold. Hand and finger grasp force tended to decrease according to the sensorineural stage of Stockholm classification and there was statistically significant difference(P=0.041, <0.001, 0.034) only on the right hand side. The tapping frequency also generally decreased according to the sensorineural stage of the Stockholm classification and there was statistically significant difference (P=0.002~0.019) only on the left hand side. Conclusions: Although there is no single standardized method that can objectively diagnose the Sensorineural component of early HAVS early, the combination of subjective symptoms, the sensorineural stage of Stockholm classification, the pain and vibrotactile threshold test, the hand and finger grasp force, and the finger agility (tapping) test can objectively detect sensorineural component of HAVS early.

      • 만성 C형 간염 환자에서 페그인터페론 알파2a와 리바비린 병합 치료중 발생한 벨마비 1예

        김일환,장제혁,유충헌,최규남,고정해,김윤정,서광원,김지현,박성재,박은택,이연재,이상혁,설상영 인제대학교 2008 仁濟醫學 Vol.29 No.-

        페그인터페론과 리바비린 병합요법은 만성 C형 간염의 일차 치료법이다. 저자들은 만성 C형 간염 환자에서 페그인터페론 과 리바비린 병합 요법 중에 발생한 벨마비 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 5년 전부터 만성 C형 간염을 앓아온 48세 남자이며, PEG-IFN α-2a 135μgm 피하주사 주1회와 하루 1200㎎의 리바비린을 투여하였다. 치료시작 후 9개월째 환자는 오른쪽 안면의 근력약화를 호소하였으며 벨마비로 진단되었다. 페그인터페론과 리바비린 병합요법을 지속하면서 관찰하였다. 환자의 벨마비는 페그인터페론 치료를 중단하지 않았음에도 3개월후 증상이 회복되고 이후 벨마비 재발 없이 현재 경과관찰 중이다. 만성 C형 간염에서 페그인터페론과 리바비린 병합 요법시 벨마비의 발생 가능성을 염두에 두어야 하겠다. A Case of Bell's Palsy Associated with Combination Therapy of Pegylated Interferon Alfa-2a (PEG-IFN) and Ribavirin for Chronic Hepatitis C Virus Infection Pegylated interferon alfa(PEG-IFN α) and ribavirin therapy is the first line treatment for chronic hepatitis C. Mild complications of the therapy are common, but more serious complications are rare. We report here a case of Bell's palsy that occurred in a patient with chronic hepatitis C virus infection during combination therapy of PEG-IFN α-2a and ribavirin. The patient was 49-year-old man with chronic hepatitis C (genotype 1b) for 8 years. He had compensated liver cirrhosis with splenomegaly. Therapy with PEG-IFN α- 2a 135mcg/week and ribavirin 1200mg/day was initiated. After 9 months of the therapy, the patient showed a loss of muscular tone on the right side of his face. A diagnosis of Bell's palsy was made. The Bell's palsy resolved over 3 months despite continuation of the combination therapy.

      • KCI등재

        긴장증의 임상적 특성에 대한 고찰

        송지영,윤도준,변재영,장환일 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.3

        26 cases(9 males and 17 females) with catatonia features on admission were analyzed in terms of its clinical characteristics. The results obtained were as follows : 1) In the diagnostic distribution, more than a half of the cases were schizophrenic disorders(57.5%) and the others were major depressions(26.9%) and schizophreniform disorders(15.4%). 2) The catatonia signs were nonspecific and evenly distributed among a variety of clinical diagnostic entities. But the signs of negativism, mutism, and posturing appeared frequently in all cases. 3) Acute onset was prevalent(65.4%), ECT was more frequently applied(61.5%) and treatment response was better(70.9%) in the catatonia group than non-catatonia. Although the definition of catatonia is not clear yet, above results support the opinions of previous studies that catatonia should be understood as a heterogenous symptom complex. And not only schizophrenia but also affective disorder are associated with catatonia features. This suggests that we have to re-evaluate the concept of Kahlbaum's old description.

      • 악안면 골격 형태에 따른 교합평면각의 변화에 관한 두부 방사선학적 연구

        오세윤,김웅철,김지환,이준석,김진완,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

        A correlation analysis was made to understand the interaction between the growth patterns of some craniofacial skeletal components and occlusal plane inclination. 5 angular measurements(S.a. Ar.a, Go.a, UGo.a, LGo.a), 6 linear measurements(ACBL, PCBL, RH. MBL. AFH. PFH) and OP/SN. obtained from 83 cephalometric tracing records, were selected and the relationship between the occlusal plane angle and those measurements were analyzed statistically. Ramus Height(r=-0.55), Posterior Facial Height(r=-0.41), were found to be negatively related with Occlusal Plane angle, while Lower Gonial angle(r= 0.35), Saddle angle(r= 0.24) were found to be positively related with Occlusal Plane angle(p(0.05). The results obtained from the above analysis were further assessed with stepwise regression analysis, using Occlusal Plane angle as a dependant variable, and RH, LGo.a and S.a as explanatory variables. Stepwise regression analysis revealed that all the explanatory variables were found to be significant.(p<0.05) [OP/SN] = -8.74-0.33(RH)+0.23(S.a)+0.20(LGo.a). (R²=0.44). This stepwise regression analysis explains, to some extent, the relationship between the growth patterns of some craniofacial skeletal components and the occlusal plane inclination. 1. The inclination of Occlusal Plane angle is noticeably related with the growth patterns of some craniofacial skeletal components, i.e. RH, PFH, Saddle angle and Lower Gonial angle 2. In high Occlusal Plane angle, the Ram us Height tends to be shorter, and the Saddle angle and Lower Gonial angle tend to be obtuse.

      • 와동형태의 설계에 따라 치아에 발생되는 응력의 변화에 관한 연구 : 인레이의 경우

        오세윤,김웅철,김지환,유진호 高麗大學校 倂設 保健大學 保健科學硏究所 1995 保建科學硏究論集 Vol.4 No.1

        Because of the anatomical form of posterior teeth, the amount of tooth reduction near the marginal ridge area in the typical, widely used intracoronal cavity will be inevitably maximal, while occlusal forces on the restoration in this area will be relatively minimal In an attempt to dicrease the amount of tooth reduction at the marginal ridge area, a modified cavity for inlay with a uniform depth of 15mm, just as in amalgam filling was designed in this study. To analize the stress development in the teeth in that cavity design, 2㎏/㎟ distributive forces were applied on the inlay restoratives and obtained results were compared with that in the typical cavity design which had a flat pulpal wall with a depth of 1.5m at the central fossa area. Analysis was done with two dimensional finite technique. The obtained results were as follows : 1. The patterns of stress distribution and displacement showed no apparent differences. 2. The stress values and the amount of displacement developed, both in inlay cast gold and in the teeth, in the cavity with a uniform depth were less than that in the cavity with a flat pulpal wall. 3. Greatest maximum principle values were concentrated around the interface between the base of inlay body and the teeth.

      • 우리나라 치과 기공사의 건강 습관에 영향을 미치는 요인

        오세윤,김웅철,김지환 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

        This investigation was carried out to evaluate the relations between the levels of health practices and their attributable factors in Korean dental laboratory technicians A questionnaire listing six groups of health practices and their related factors was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental laboratory technicians filled out the questionnaires and returned them. Before the start of main survey, a pilot survey was carried out for validity test of the questionnaire. All the data obtained were corded and analyzed with PC/SAS 6.12 program. The level of inappropriate health practices was the highest in irregular exercise(85.3%), and followed by smoking(61.0%), drinking of alcohol(59.1%), irregular eating habits(45.6%), inappropriate sleep duration(32.2%), and obesity(9.4%). Statistically significant factors by multiple logistic regression analyses were sex. work part in obesity: age. work area. number of employees in hours of sleeping: sex, self assessed health status, health examination, work area, work hours in eating habits: sex, marital status, education in smoking : sex in drinking of alcohol : self assessed health status : health examination, work hours in exercise '. and sex, work hours in health practice index. With the above considerations in mind, the levels of health practices in Korean dental laboratory technicians was relatively low and that was attributable to most of the sociodemographic characteristics, health examination and health status and work history. It is suggested that health promotion programs for promoting self-assessed health status, carrying out health examination, reducing work hours, and measures for elevating the level of health practice of male techinicians be necessary.

      • 치과기공사의 직업만족도 측정을 위한 설문도구의 개발

        오세윤,김웅철,김지환,이병기,유진호,김태석,이준석,이주호 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.2

        Conflicts between individuals are quite natural and they can act as an positive contributing factor not only to the development of an individual but also to the organization to which one belongs. But too much conflicts will always induce dissatisfaction and stresses, which will be destructive and harmful to all of them, and that is why we are always tying to seek(find) out the causes for the origination of conflicts and remedies to cope with them effectively. The present study, as the first one in a series of studies which our researchers contemplate executing, was designed to develop a measure of job satisfaction for dental laboratory technicians. One job satisfaction measure and two job satisfaction related measures, one for faithfulness for the job and the other for environmental characteristics of dental laboratory were newly developed. The newly developed measures were comprised of a total of 38 items, which were each 12 items for job satisfaction and faithfulness for the job and 14 items for environmental characteristics of dental laboratory With the aid of factor analysis for principal components and categorization of items by panel of professionals, items of each measure were grouped into 2-4 subscales. Contribution to internal consistency was the fina) criterion for an item's inclusion in a subscale. Internal consistency reliability of each item was attested through the statistical analysis on the data obtained from 55 structured questionnaires. Reliability of internal consistency of subscales in each measure of job satisfaction and faithfulness for the job ranged from 0.74 to 0.79 and 0.90-0.91 respectively. The result from this research came to draw the following conclusions. 1. Validity and internal consistency reliability of all the items of each measure was attested. 2. The newly developed measure of job satisfaction was found to be appropriate for (measuring the degree of job satisfaction of) dental technicians, as well as for (other) dental office personnels.

      • 와동형태의 설계에 따라 치아에 발생되는 응력의 변화에 관한 연구 : 1. 온레이의 경우

        오세윤,김웅철,김지환 高麗大學校 倂設 保健大學 保健科學硏究所 1994 保健科學論集 Vol.20 No.1

        Because of the anatomical form of posterior teeth, the amount of tooth reduction at the cuspal area in the typical intracoronal cavity will be inevitably maximal, while stress development on the restoration in this area will be relatively minimal. In an attempt to decrease the amount of tooth reduction at the cuspal area, two modified cavities were newly designed in this study. They had a decreased pupal depth of 1mm at the cuspal area and offsets with the depth of 0.5 ~ 1.0mm were formed at the central fossa area. The Von Mises stresses developed in the gold restoratives and in the teeth were compared with that in the typical intracoronal cavity, which had a simple flat pulpal floor with 1.5mm pulpal depth at the central fossa area. Stress analysis was done with two dimensional finite technique. The obtained results were as follows: 1. The newly modified cavity designs were found to be more advantageous in stress distribution. 2. The effect of offset depth was not significant, but some relationship between the offset depth and stress distribution was found.

      • Systemic Lupus Erythematosus를 동반한 Multiple sclerosis

        이지현,이기주,윤성호,부귀범,손현화,박유환,정춘해,김진호,정원영 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

        Multiple sclerosis and lupus erythematosus are chronic, potentially disabling diseases of unknown cause. It is a rare occasion that the finding of both diseases occurs in one patient. Because both diseases may affect the central nervous system, it may be difficult at times to differentiate symptoms of lupus erythematosus from those of multiple sclerosis. As far as we know, there was no case report of SLE in multilple sclerosis in Korea. We report a case of multiple sclerosis accompanied by SLE.

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