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하지훈 The English Linguistic Science Association of Kore 2002 English Linguistic Science Vol.8 No.-
The purpose of this study is to design a model for the development of ‘English lesson plans’ focusing on improvement of cultural understanding in elementary English education utilizing the Internet. This study examined the use of the Internet as a teaching tool for English culture education. The reasons for devising new lesson plans utilizing the Internet are as follows. First, in this fast-paced information era, the Internet allows people to study beyond time and space. The Internet is a necessity in daily life and will play a more leading role in education in terms of content and will be instrumental in the future. It is necessary for the nation and individuals to use the Internet in order to effectively study English. The Internet not only allows for the sharing of information but also drastically changes education of English. Second, it is important that learners understand English culture. It is necessary for learners to learn the target culture as well as the language in order to get rid of false stereotypes or misunderstandings about the target culture, and successfully communicate with native speakers. Third, learners use the Internet as a main source of educational media. There are many ways to learn the target culture in the process of English learning, but these have a number of limitations. One of the solutions to this program is the learning through the Internet. It is a valuable tool for learning the target culture in English learning, and to introduce the Internet as an efficient too for learning the target culture. In order to achiever the main purpose, a background for using the Internet for English education and culture teaching must be established and an investigation of the actual conditions of elementary schoolchildren should be conducted. From a review of research findings that analyzed students’ actual conditions, and English lesson plan for elementary schoolchildren was designed. The basic principles of this leson plan were based on the 7th English curriculum for elementary schools. The lesson plan combined linguistic competences and culture, the objectives of the unit. In conclusion, the results of this study show that the Internet is the most suitable way to teach and learn English. The contents of lesson plans are made of basic Internet-based activities for learners to experience culture-based activities with interest and practice language functions naturally and effectively. This method can also be adjusted both for on-line classrooms and for traditional off-line classrooms. I expect that this study will help Korean media education fields to research new media including multimedia like that on the Internet and introduce new methods of their own.
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개선된 중성염 전해공정을 이용한 모의 방사성금속폐기물의 제염
이지훈,육완이,양호연,하종현 대한방사선 방어학회 2002 방사선방어학회지 Vol.27 No.2
원자력발전소에서 주로 발생되는 금속폐기물인 탄소강을 중성염전해질인 1.7M의 황산나트륨(Na₂SO₄)과 질산나트륨(NaNO₃)을 이용하여 기존전해제염과 개선된 전해제염공정의 비교실험을 수행하였다. 양극은 인코넬, 음극은 티타늄으로 하여 상온에서 1시간동안 반응시켜 금속폐기물 모재의 weight loss, 두께변화, 전해질 내 침전물농도, SEM을 이용하여 제염전후의 금속폐기물 표면의 형상을 분석하였다. 실험결과 개선된 전해제염 적용시 전해질 종류별 전류밀도 변화에 따른 실험에서는 전류밀도가 0.1∼0.6A/cm²으로 증가함에 따라 1.7M의 황산나트륨 적용시 금속폐기물 모재의 두께변화는 0.48±0.005∼67.7±0.02um, 1.7M의 질산나트륨 적용시에는 0.06±0.005∼17.7±0.05로 나타나 같은 전류밀도에서 황산나트륨 적용시 금속폐기물 모재의 표면 제염효율이 더욱 높은 양상을 보였다. 또한 전류밀도 0.3 A/cm² 및 1.7M의 황산나트륨의 조건에서 개선된 전해제염 적용 시 9.8±0.01um의 금속폐기물 두께변화를 보여 기존전해제염 적용시인 3.7±0.03um의 금속폐기물 두께변화보다 2배 이상의 표면 제염효과를 보였다. Conventional and modified electrolytic decontamination experiment were performed in the 1.7 M solution of sodium sulfate and sodium nitrate for decontamination of carbon steel as the simulated metal wastes which have been produced in large amounts from nuclear power plants. Anode and cathode were used as inconel and titanium respectively. The reaction time and temperature were 1 hr and 25℃. The analyses were performed of the characteristics such as weight loss and thickness change of metal waste, suspended solid in electrolyte and SEM observation. In modified electrolyte decontamination system with increased current density ranged from 0.1 to 0.6 A/cm², the metal waste showed thickness changes of 0.48±0.005 to 67.7±0.02um in 1.7 M sodium sulfate and those of 0.06±0.005 to 17.7±0.05um in sodium nitrate. Metal waste in modified electrolyte decontamination system showed the thickness change of 9.8±0.01um while it reacted up to 3.7±0.03um in conventional system with 0.3 A/cm² of current density and 1.7 M sodium sulfate. Decontamination efficiencies of modified electrolytic process are much higher than that of conventional electrolytic process when both are applied to metal waste.
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권세훈,김형호,강지인,하재하,한경택,이재록,김동민,권용은,윤성호,이승일 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Scrub typhus is a potentially fatal infectious disease caused by the organism Orientia tsutsugamushi. Clinical manifestations are fever, skin rash, eschar and varying degree of respiratory distress. The pleural effusion in scrub typhus is rare and secondary to the destruction of vascular endothelium. Because the respiratory symptoms are generally mild and the pleural effusion in scmb typhus is rare than in interstitial pneumonia, there are few comments about the characteristics of scmb typhus with pleural effusion. So we made the comparative study of scmb typhus patients between with pleural effusion and without pleural effusion. 연구배경 치명적일 수 있는 감염질환 중 하나인 쯔쯔가무시중(Scrub typhus)에서 드문 흉막삼출을 동반한 환자에 대한 고찰은 다른 문헌에서도 자주 언급되지 않았다. 따라서 본 저자들은 흉막삼출이 있는 경우와 없는 경우에 따른 쯔쯔가무시중 환자들을 비교하고자 하였다. 방법 2003년에서 2006년까지 조선대학교 병원 내과에 입원중인 환자 중 쯔쯔가무시중 진단을 받은 총 109명의 환자를 대상으로 하여 흉부 X선 검사 및 혈청학적 검사(CPK, LDH, ESR, CRP, AST, ALT, ADA), 혈액학적 검사(WBC, PLT) 및 백분율 검사등을 실시하였다. 결과 흉막삼출이 있는 환자들의 경우 흉막 삼출이 없는 환자들에 비해 ESR 수치가 통계학적으로 의의있게 높았다(p-vaule < 0.05). 결론 흉막삼출 유무에 따른 쯔쯔가무시중 환자간의 비교에 있어 ESR 수치가 통계학적인 의의를 가졌다.
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이유진,하지훈 The English Linguistic Science Association of Kore 2000 English Linguistic Science Vol.5 No.-
The main purpose of this study is to show a more effective way to study English via the Internet, and to give mare information about how to use it in the class with many students. Using the Internet in English language classroom has lots of advantages and merits. Firstly, it is the best substitute for native spearkers in English education. Secondly, as it offers a virtually real environment to leasers, it is possible for us to communicate with others. Thirdly, it allows English learners to face the culture of English, motivating them to learn English by eliminating the cultural bounds. Fourthly, it helps us overcome the negative attitude which can be easily found in English language classrooms. In this study, I have researched the Internet use in English language learning: vocabularies, communication activity and supplementary materials. A large number of students showed interest and satisfaction in studding English on the Internet. In conclusion, in this study it has been proved that the Internet was a very helpful device in teaching and learning English in school, that a sufficient number of computers should be provided in classes and that further research in this field is urgently needed.
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거꾸로 수업(Flipped Learning)에 대한 과학 교사의 인식 분석
신영준,하지훈 이화여자대학교 교과교육연구소 2016 교과교육학연구 Vol.20 No.2
본 연구의 목적은 거꾸로 수업의 적용에 대한 시사점을 얻기 위해 초·중·고등학교 교사 100명을 대상으로 거꾸로 수업에 대한 교사의 인식을 파악하여 과학교과에 대한 거꾸로 수업의 적용을 위한 정보를 얻는 데 있다. 이를 위해 전문가 집단을 통해 거꾸로 수업에 대한 교사 인식 문항을 개발하였다. 교사의 인식에 대한 조사 결과 거꾸로 수업에 대한 교사의 이해 정도는 기존 연구(Park & Cha, 2015)에 비해 높아졌으며, 교사들이 과학 교과를 거꾸로 수업 적용이 적절한 교과로 인식하고 있다는 사실도 다시 확인하였다. 거꾸로 수업 도입의 영향과 필요성에서 모두 다소 긍정적인 수준인 보통 이상의 응답을 보였지만, 도입 필요성이 교육에 미치는 영향에 비해 다소 낮은 응답을 나타냈다. 수행 준비 정도에 대해 교사들은 전반적으로 다소 부족하다는 의견을 보였고, 기존 수업에 비해 거꾸로 수업이 더 많은 시간과 노력이 필요하다는 인식을 가지고 있었다. 거꾸로 수업을 성공적으로 수행하기 위해 필요한 능력으로 수업설계능력을 선택한 교사가 가장 많았으며, 학습자료 제작 능력이 그 다음이었다. 이는 Shin et al.(2016a)에서 교사들이 부담을 느꼈던 부분과 일치한다. 이와 같은 연구 결과를 통해 거꾸로 수업의 도입에 대해 교사들의 일반적인 인식은 다소 긍정적이나 실제 적용에 대해 거부감을 가지거나 수행을 위한 준비가 부족하다는 인식을 하고 있음을 알 수 있었다. 과학 교과의 경우 다른 교과에 비해 거꾸로 수업 적용에 대한 교사의 저항은 적을 것으로 예상할 수 있었고, 교사들이 기존 과학 수업의 문제점을 해결할 수 있는 대안으로 거꾸로 수업을 인식하고 있음을 확인할 수 있었다. The purpose of this study was to obtain information on the application of flipped learning and confirm the applicability of flipped learning for science class, through investigating perceptions of 100 teachers in elementary, middle and high school. For this purpose, the questions for teacher’s perceptions about flipped learning were developed by the expert group. The results were as follows : The understanding of flipped learning was higher than in previous studies (Park& Cha, 2015), and the fact that teachers are aware of science as an appropriate subject for the application of flipped learning was confirmed again. Most teachers selected instructional design skills as the most needed ability for successful implementation of flipped learning, which is followed by material production skills. Two skills are related to difficulties presented in Shin et al.(2016a). Based on these results, teachers’ opposition to flipped learning applied in science class is expected to be low, compared to other subjects. It was confirmed that the high applicability of flipped learning may be a solution to the current science class in which teachers’ lecture takes up most part of the lesson.
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수종 한약제의 위암세포에 대한 항암작용 효능 검색 및 약리작용에 관한 분자생물학적 연구
김진성,이지향,류봉하,박재훈,지성길,유진화 대한한방종양학회 1999 대한한방종양학회지 Vol.5 No.1
Traditional oriental medicines have ken used for tmament of various kinds of human cancers for long times and some of mem proven to k effective clinical-. However, the pItarmacologica1 actions ad mechanisms related to cancer treatment are generally unknown. In an effort to clarify the action mechanisms of several oriental medicines used for cancer treatments. we planned this experimental praedura. We selected Cadyceps sinensis (동충하초), Punellae Herba (夏柱草), Rehmanniae Radix (熟地黃), Paeoniae Radix (白均案), Oldedamar Herba (白花批告草), Partulaceae Herba (馬首算), Scdopendrasubspinipes mudans (蜈松), Mylabris Phalerara (班藝), Phellinus igniarius(蔡黃), Ganodermae Lignum(靈芝) for evaluation, which have ken used for patients of gastric cancers. The twenty grams of medicines were boiled in 100㎖ of water for 1 hour and filtered with O.2㎛ pore-sized filter unit to remove insoluble particles. Initially we evaluated the effects oriental medicines on growth inhibition in stomach cancer cells. The gastric cancer cell line, AGS, was cultured in RPMI l640 supplemented with lO% heat-inactivated fetal bovine serum and Heated with lO㎕ oriental medicines per l㎖ of medium up to 48 hours. The specimens were subjected to MTT assay for evaluation of growth inhibition. We found mat Mylabris piulema (班 察) markedly supmessed the growth of cancer cells as shown in results. Next, we checked the effects of orielntl medicines on cancer on cell cycles and apMonsis. Mylabrls phalerata (반모) inhibited cell cycle progression of Canea cells a compared with connol cells and cells treated with other medicines. In addition, Mylabri phalerata (반모) induced apptosis in 30-40% of stomch cancer cells within 24 hours. Other oriental medicines used for this experiments did not show apoptosis-inducing effects on cancer cells. Finally, we determined the expmSSion levels of genes associated with cell cycle Md apoptosis. The expressions of bcl-2 and bcl-XL were downregulated by the treamerm of Mylabris phalerata (반모). However, the expression levels of genes related to cell cycles were not altered significantly. In conclusion, we found that Mylams phalerata (반모) has in vivo gowth-inhibiting ad apptosis- inducing effects on stomach cancer cells. However, we think that at least animal experiments are necessay for evduations.
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Ha, Mi-Kyoung,Song, Young Hoon,Jeong, Soo-Jin,Lee, Hyo-Jung,Jung, Ji Hoon,Kim, Bonglee,Song, Hyo Sook,Huh, Jeong-Eun,Kim, Sung-Hoon Pharmaceutical Society of Japan 2011 BIOLOGICAL & PHARMACEUTICAL BULLETIN Vol.34 No.9
<P>Chronic inflammation of rheumatoid arthritis (RA) is promoted by proinflammatory cytokines and closely linked to angiogenesis. In the present study, we investigated the anti-inflammatory effects of emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) isolated from the root of <I>Rheum palmatum</I> L. in interleukin 1 beta (IL-1β) and lipopolysaccharide (LPS)-stimulated RA synoviocytes under hypoxia. Emodin significantly inhibited IL-1β and LPS-stimulated proliferation of RA synoviocytes in a dose-dependent manner under hypoxic condition. Also, enzyme linked immunosorbent assay (ELISA) revealed that emodin significantly reduced the production of pro-inflammatory cytokines [tumor necrosis factor-alpha (TNF-α), IL-6 and IL-8], mediators [prostagladin E<SUB>2</SUB> (PGE<SUB>2</SUB>), matrix metalloproteinase (MMP)-1 and MMP-13] and vascular endothelial growth factor (VEGF) as an angiogenesis biomarker in IL-1β and LPS-treated synoviocytes under hypoxia. Consistently, emodin attenuated the expression of cyclooxygenase 2 (COX-2), VEGF, hypoxia inducible factor 1 alpha (HIF-1α), MMP-1 and MMP-13 at mRNA level in IL-1β and LPS-treated synoviocytes under hypoxia. Furthermore, emodin reduced histone deacetylase (HDAC) activity as well as suppressed the expression of HDAC1, but not HDAC2 in IL-1β and LPS-treated synoviocytes under hypoxia. Overall, these findings suggest that emodin inhibits proinflammatory cytokines and VEGF productions, and HDAC1 activity in hypoxic RA synoviocytes.</P>
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