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Ji-Hoo Yook,Dong-Wook Lee,Min-Seok Kim,Yun-Chul Hong 대한직업환경의학회 2018 대한직업환경의학회지 Vol.30 No.-
Background: Bus drivers are known to be highly at risk of cardiovascular diseases. In this study, we assessed the cardiovascular disease prevalence of bus company employees in Seoul, South Korea, and compared the results to those of general workers. Methods: We analyzed the 2014 Korean National Health Insurance (NHI) data and defined hypertension, diabetes, dyslipidemia, ischemic heart disease, and cerebrovascular disease based on the KCD-6 medical diagnoses. We used bus company employees as surrogate participants of bus drivers due to the characteristics of Korean NHI data. We identified bus company employees in Seoul based on one’s workplace which the insurance is registered. The prevalence of five diseases was compared between the bus company employees and general workers. We also calculated the odds ratios (OR) of five diseases between the bus company employees and general workers. To compensate the vast demographical differences between the two groups, we performed propensity score matching. Results: Bus company employees have higher OR for having hypertension (OR 1.33, 95% CI: 1.28-1.39), diabetes mellitus (1.14, 95% CI: 1.08-1.22), and dyslipidemia (1.23, 95% CI: 1.17-1.29) than the general workers or propensity score matched controls. However, the OR of having ischemic heart disease were not significant. The OR of cerebrovascular disease were lower in bus company employees than in the general workers after adjusting the covariates, but similar in the propensity score matched model. Conclusion: This study showed that the ORs of cardiovascular disease risk factors are high in bus company employees when compared to the general working population. Further studies with the longitudinal design should be conducted to confirm the causal association.
유두주위게실이 내시경유두큰풍선확장술을 이용한 총담관 결석 치료에 미치는 영향
이지원 ( Ji Won Lee ),김정호 ( Jung Ho Kim ),김연석 ( Yeon Suk Kim ),최현석 ( Hyun Seok Choi ),김주승 ( Ju Seung Kim ),정석후 ( Seok Hoo Jeong ),하민수 ( Min Su Ha ),구양서 ( Yang Suh Ku ),김연수 ( Yun Soo Kim ),김주현 ( Ju Hyun K 대한소화기학회 2011 대한소화기학회지 Vol.58 No.4
Background/Aims: Periampullary diverticulum (PAD) causes difficulty in the extraction of common bile duct (CBD) stones with conventional endoscopic therapy. Our study was designed to evaluate the effect of PAD on endoscopic large balloon dilation (EPLBD) with/without limited endoscopic sphincterotomy (EST) for CBD stone treatment. Methods: We retrospectively reviewed cases of 141 patients treated CBD stones by EPLBD with/without limited EST at Gachon Gil Medical Center from September 2008 to February 2010. PAD were classified into three groups according to the location of the papilla and diverticulum. Clinical parameters, endoscopic parameters, and procedure outcomes were analyzed. Results: PAD were identified in 46.1% (65/141), with 23 male (35.4%) and 42 female (64.6%) and a mean age of 72.9±11.1 years. Mean diameter of the stones was 14.8±6.0 mm and mean diameter of CBD was 21.6±7.7 mm. PAD group was significantly older than control group (72.9 vs. 68.6, p=0.043) and the incidence of large stone (≥15 mm) was higher in PAD group (60.0% vs. 42.1%, p=0.034). Success rate of complete removal of stones in the first session was 32/65 patients (49.2%) and overall successful complete stone removal rates was 63/65 (96.9%). There was no significant difference between the PAD and control groups in success rate. Major complications were similar between two groups. Conclusions: PAD is associated with an increased incidence of large bile duct stones and older age. PAD seems to not increase technical failure rate or complication risk on EPLBD with/without limited EST. (Korean J Gastroenterol 2011;58:201-207)
The establishment of KORCC (KOrean Renal Cell Carcinoma) database
Byun, Seok-Soo,Hong, Sung Kyu,Lee, Sangchul,Kook, Ha Rim,Lee, Eunsik,Kim, Hyeon Hoe,Kwak, Cheol,Ku, Ja Hyeon,Jeong, Chang Wook,Lee, Ji Youl,Hong, Sung Hoo,Kim, Yong-June,Hwang, Eu Chang,Kwon, Tae Gyun The Korean Urological Association 2016 Investigative and Clinical Urology Vol.48 No.6
<P><B>Purpose</B></P><P>The purpose of this article is to report establishment of the 1st Web-based database (DB) system to collect renal cell carcinoma (RCC) data in Korea.</P><P><B>Materials and Methods</B></P><P>The new Web-based DB system was established to collect basic demographic and clinicopahtological characteristics of a large cohort of patients with RCC in Korea. Data from a total of 6,849 patients were collected from 8 tertiary care hospitals that agreed to participate in organizing the Korean Renal Cell Carcinoma (KORCC) study group as of 1 July 2015. Basic demographic and clinicopathological characteristics were collected. The data of patients who underwent surgical treatments were analyzed to characterize Korean RCC.</P><P><B>Results</B></P><P>We established the 1st Web-based DB of Korean RCC, a database comprising renal mass management cases from multiple centers in Korea. The data of 5,281 patients who underwent surgical management (mean follow-up, 32 months) were analyzed. The most common symptom was incidentally detected renal mass (76.9%). Clinical T1a was the most common (54.3%) stage and mean tumor size was 4.8±4.2 cm. Radical nephrectomy accounted for 62.7% of cases and an open approach was used in 50.7% and 52.2% of radical and partial nephrectomies, respectively. The 5-year overall, cancer-specific and recurrence-free survival rates were 88.1%, 92.2%, and 88.0%, respectively.</P><P><B>Conclusions</B></P><P>We report the 1st establishment of a Web-based DB system to collect RCC data in Korea. This DB system will provide a solid basis for the characterization of Korean RCC.</P>
Magnesium sulfate 와 Ritodrine hydrochloride의 조기진통 억제효과 및 안정성에 대한 비교연구
박후철(Hoo Chul Park),왕중서(Joong Seo Wang),최은주(Eun Ju Choi),정지영(Ji Young Jeong),이동규(Dong Gyu Lee),박정석(Jeong Seok Park),강상대(Sang Dae Kang) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.10
목적: 조기진통 치료에 있어서 magnesium sulfate 와 ritodrine hydrochloride의 효과 및 안전성에 대하여 연구하였다. 방법: 1996년 7월 1일부터 1998년 12월 31일까지 만 2년 6개월 동안 마산 파티마병원 산부인과에 입원 가료한 120례의 조기진통 환자 중 magnesium sulfate를 투여했던 40례와 ritodrine hydrochloride를 투여했던 40례를 연구군으로 절대안정요법 및 수액요법만으로 치료했던 40례를 대조군으로 선정하여 효과 및 안전성에 대하여 비교 분석하였다. 결과: 1. 조기진통의 빈도는 6.0∼7.7%를 보였다. 2. 조기진통의 위험인자로는 조기양막파수, 중증 전자간증, 조산의 기왕력, 쌍태아임신, 전치태반, 태아기형, 자궁경관무력증, 태반조기박리, 자궁근종 순 이었으며, 뚜렷한 원인인자가 없는 경우가 28.6%를 차지하였다. 3. 임신지연기간은 magnesium sulfate로 치료했던 군은 14.95±11.98일, ritodrine으로 치료했던 군은 17.48±13.41일로 두 군간에 유의한 (p<0.05) 차이가 없었으나 대조군의 11.60±14.74일에 비해 두 군 모두에서 증가하였으며, 분만시기도 magnesium sulfate군은 35.10±2.81주, ritodrine군은 35.00±2.49주로 역시 두 군간의 유의한 (p<0.01) 차이는 없었으나, 대조군의 34.95±2.71주에 비해 두 군 모두에서 증가하였다. 4. 치료성적은 magnesium sulfate로 치료했던 군은 완전성공률 12.5%, 불완전성공률 35.0%로 총 성공률 47.5%였으며, ritodrine으로 치료했던 군은 완전성공률 7.5%, 불완전성공률 45.0%, 총 성공률 52.5%로 두 군간에는 유사하였으나 대조군에서는 완전성공률 2.5%, 불완전성공률 27.5%, 총 성공률 30%만을 보였다. 5. 부작용으로는 magnesium sulfate 투여군에서 홍조, 태아곤란증, 흉부 불편감, 태반조기박리 순이었으나, ritodrine 투여군에서는 산모의 빈맥, 현기증, 두통 순 이었으며, 전혀 부작용이 없는 경우는 magnesium sulfate군에서 75.0%로 ritodrine군의 7.5% 보다 현저히 많았다. 2차 약제 추가투여가 필요한 경우는 magnesium sulfate군과 ritodrine군이 각각 15.0%, 12.5%로 유사하였으나, 그 주원인은 magnesium sulfate군은 자궁수축이 조절되지 않는 경우가 대부분 이었지만, ritodrine군은 부작용이 심한 경우가 더 많았다. 6. Magnesium sulfate와 ritodrine 투여군 모두에서 혈압에는 별 영향을 미치질 않았는데 반해 (p<0.01), 맥박수에서는 magnesium sulfate 투여군에선 유의한 (p<0.05) 차이가 없었으나 ritodrine 투여 군에선 현저하게 (p<0.05) 증가하였다. 진통억제 후에, 혈당치는 두 군 모두에서 유의한 (p<0.01) 차이를 보이질 않았으나 혈액내 칼륨치와 칼슘이온은 각각 유의하게 (p<0.05, p<0.01) 감소하였다. 결론: magnesium sulfate 와 ritodrine hydrochloride의 안전성과 효과면에서 유의한 차이가 없었다. Objectives: The purpose of this study was to evaluate the efficacy and safety of magnesium sulfate and ritodrine hydrochloride in the management of preterm labor. Methods: This study was undertaken to assess the clinical efficacy & safety of magnesium sulfate and ritodrine hydrochloride on 120 patients admitted with preterm labor from Jul. 1, 1996 to Dec. 31, 1998. Results: 1. The incidence of preterm labor was showed 6.0∼7.7% of total number of delivery. 2. The risk factors of the preterm labor were premature rupture of membrane, severe preeclampsia, previous preterm delivery, twin pregnancy, placenta previa, fetal anomaly, incompetent cervix, placental abruption, and uterine myoma in order, but 28.6% of preterm labor had no apparent risk factors. 3. The days gained in uterus was not statistically different between the magnesium sulfate group and the ritodrine group (p<0.05) but longer in the two groups than the control group. And the delivery time was also not statistically different between the magnesium sulfate group and the ritodrine group (p<0.01) but significantly increased in the two groups than the control group. 4. The rate of complete and incomplete success was similar as 12.5% and 35% (total success rate 47.5%) in the magnesium sulfate group, 7.5% and 45% (total success rate 52.5%) in the ritodrine group but only 2.5% and 27.5% (total success rate 30%) was showed in the control group. 5. The side effects were much more in the ritodrine group than the magnesium sulfate group. The patients requiring second-line therapy were similar in the both groups but the main cause was uncontrolled uterine contraction in the magnesium sulfate group, and intolerable side effects in the ritodrine group. 6. The pulse rate was not statistically different in magnesium sulfate group but markedly increased in ritodrine group (p<0.05). After managements of preterm labor, the serum potassium and ionized calcium level was significantly decreased in the two groups (p<0.05, p<0.01). Conclusion: There was not significantly different efficacy and safety of magnesium sulfate and ritodrine hydrochloride in the management of preterm labor.
Lee Ji Min,Lee Kang-Moon,Kang Ho Suk,Koo Ja Seol,Lee Hyun Seok,Jeong Seok-Hoo,Kim Jung Ho,Kim Dae Bum 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.4
Background/Aims: Low-volume preparations for colonoscopy are gaining attention for their higher acceptability. However, the efficacy and safety of oral sulfate solution (OSS) preparations in patients with ulcerative colitis (UC) has not been well known. Therefore, we aimed to compare OSS and 2-L polyethylene glycol with ascorbic acid (PEG+Asc) for bowel preparation in inactive UC. Methods: A multicenter, randomized, single-blind study was conducted at six tertiary referral hospitals in Korea. Outpatients with UC who had stable disease activity were randomly allocated to the OSS group or the 2-L PEG+Asc group for bowel preparation before colonoscopy. The study outcomes included treatment efficacy, safety, tolerability, and acceptability. Bowel cleansing was assessed using the Boston Bowel Preparation Scale and rated as successful cleansing if the score was ≥6. Patient acceptance and tolerability were assessed using a 4-point ordinal scale. Additionally, disease activity and laboratory data before and after colonoscopy were evaluated to check for safety. Results: The OSS and 2-L PEG+Asc groups included 92 and 93 participants, respectively. No significant between-group difference was noted in successful cleansing (OSS [96.7%] vs 2-L PEG+Asc [97.8%], p=0.64). Moreover, the safety, acceptance, and tolerability were not significantly different (all p>0.05). Furthermore, no significant changes were found in serum electrolytes or disease activity in either group. Conclusions: OSS is effective for colonoscopy cleansing, has acceptable tolerability, and does not affect disease activity; thus, it can be used safely for bowel preparation in patients with inactive UC.
Acute Urinary Retention in a 47-month-old Girl Caused by the Giant Fecaloma
Park, Ji Sook,Park, Tae-Jin,Hwa, Jung Seok,Seo, Ji-Hyun,Park, Chan-Hoo,Youn, Hee-Shang The Korean Society of Pediatric Gastroenterology 2013 Pediatric gastroenterology, hepatology & nutrition Vol.16 No.3
We present a case of a 47-month-old female suffering from acute urinary bladder neck obstruction and bilateral hydronephrosis secondary to a fecaloma. Fecaloma is defined as an accumulation of inspissated feces in the colon or rectum giving the appearance of an abdominal mass. A fecaloma can be developed by diverse causes and the causes of the fecaloma in this case were septum reformation after the Duhamel procedure and long-term constipation. Chronic constipation is very common at outpatient clinic. However, acute urinary retention and voiding difficulty caused by fecaloma in the giant Duhamel pouch has never been reported in Korea. We would like to present our case with acute urinary retention due to a fecaloma and suggest that fecaloma might be considered as one of the causes for acute urinary retention, especially in cases with previous Duhamel operation for repair of Hischsprung disease.