전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

레드머드와 광촉매를 사용한 칼라콘크리트의 생태 도로포장 조성에 관한 실험적 연구

정동영,최경락,홍종현,김문훈 탐라대학교 지역개발연구소 2007 지역개발연구 Vol.2 No.-

정수장슬러지의 고형물량에 대한 예상치의 비교

문용택,김정현 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

The quantity of residuals generated from water treatment plants depends upon the raw water quality, dosage of chemicals used, performance of the treatment process, method of sludge removal, efficiency of sedimentation, and backwashing frequency. Sludge production by the physical separation of SS occurs under quiescent conditions in the primary clarifier, where suspended solids are allowed to settle and to consolidate on the clarifier bottom. Raw primary sludge results when the settled solids are hydraulically removed from the tank. The relative solid and liquid fractions of a slurry are most commonly described by the solids concentration, expressed as ㎎/L or percent solids. The purpose of the present investigation is to correlate predicted value with practical value on the quantity of alum coagulant sludge.

중합 및 미중합 소와열구 전색제의 잔류 단량체 용출에 관한 연구

문현정,임범순,김철위 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

Triethyleneglycol dimethacrylate(TEGDMA), Bis-glycidyl dimethacrylate(Bis-GMA), and Urethane dimethacrylate(UDMA) are components of dental resin-based pit & fissure sealants which may be released and enter the body via skin, dentin and pulp. A recent study reported that hormone-mimicking compound, Bisphenol-A leached into saliva from dental pit & fissure sealants. The purpose of this study was to identify and quantify Bisphenol-A and other leachable components that might be released from polymerized and unpolymerized dental pit & fissure sealants. Seven commercially available light-cured resin-based pit and fissure sealants as the experimental group(Concise, Pit & Fissure sealant, Elite, Fissurit F, Teethmate F-1, Ultraseal XT Plus and Helioseal) and one composite resin (Z100) as the control group were studied. Specimens were polymerized by using a 1 mm (thickness) x 0.5 mm (diameter) acrylic mold which were weighed and immersed in 99.99% ethyl alcohol for 4 min, 2 and 12 hrs., 3 and 7 days. Solutions were analyzed by using High-Performance Liquid Chromatography(HPLC) to detect various leachable components. Three specimens of each sealants were tested. From the experiment, the following results were obtained : Specimen peaks with retention times of 2.28, 3.37, 6.18 and 7.39 min were identified as BPA, TEGDMA, UDMA, and Bis-GMA respectively. BPA was not detected in eluates from unpolymerized specimens(CON, ELI, HEL, Z100). PFS and ELI leached significantly more BPA than other specimens did(p<0.05). Generally, the quantity of TEGDMA leached as a function of aging periods showed no statistically significant difference(p>0.05), but in TFI and UXP group, they showed statistically significant difference after 7 days(p<0.05). The amount of Bis-GMA and UDMA elution after 3 days showed statistically significant difference(p<0.05). The monomers(BPA, TEGDMA, Bis-GMA, and UDMA) of pit and fissure sealants were leached within a range of 0.0023∼2.94% of the original weight of the sealants cured for 4 min, 2 and 12 hours, 3 and 7 days.

LC-MS/MS를 이용한 S.D. Rat 혈장 중 Arctiin 분석법 개발

송병정,채정우,백현문,권광일 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

KIOM-MA128 is a novel oriental herbal medicine which is for atopic dermatitis and asthma. The purpose of this study was to develop on analytical method of arctiin in rat plasma after oral administration of KIOM-MA128. Analyte was separated on a Atlantis dC18 reverse phase column, using gradient mobile phase (A:B = acetonitrile: 0.1% formic acid in water) at a flow rate of 0.3 mL/min. Detection was performed by electrospray positive ionization mass spectrometry using multiple reaction monitoring of the transitions of arctiin at m/z 552.4 → 372.8 and internal standard (carbamazepine) at m/z 237.0 → 194.5. The limit of quantification was 1 ng/mL for arctiin. The precisions were lower than 15% and the accuracy was between – 12.21 and 3.2%. The maximum concentration found in plasma samples was 4.1 ng/mL. The present method was successfully developed for detecting arctiin in plasma and this results would be utilized to the further study.

Expansin으로 형질전환 된 담배의 생장 특성

신하정, 성현정, 백승준, 김보미, 엄유리, 조은정, 정찬문, 이이 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

-본문참고-

남성유방에서 발생한 침윤성 선암종 1 예 : Report of a case

정유경,문현준,전호종 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Male breast cancer is rare compared to female breast cancer, about 1% or all breast cane or. The cause of male breast cancer is as poorly understood, but several etiologic factors have been suggested in the literature. Proposed risk factors include exogenous estrogen exposure, Klinefelter’s syndrome, gynecomastia and familial clustering. All of the microscopic types identified in the female breast have been encountered in males : the most common type is infiltrating duct carcinoma. Most often, it presents as a painless lump and subareolar in origin. Comparison with female breast cancer reveals no difference with regard to incidence of positive axillary lymph nodes. However there is a sightly lower survival rate for men. The stage of disease is the only parameter that significantly affects outcome. We report a case of breast cancer arising right subareolar area in a 57 year-old male. There were no familial history, Klinefelter's syndrome and microscopic evidence of gynecomastia. Histologically, this tumor was infiltrating duct carcinoma disposed in nests sometimes glands .

AMPS 시스템과 주파수를 공유하는 CDMA시스템의 링크 해석

문병현,손병국,최정희 대구대학교 과학기술연구소 1999 科學技術硏究 Vol.5 No.5

In this paper, the forward and reverse link cellular capacities analysis of code division multiple access (CDMA) is performed when the systems are sharing the same frequency band. It is assumed that the frequency reuse pattern K=5 is used for the analysis. Formule that describe the relationship between the number of CDMA and AMPS users for a given carrier to interference ratio (GI) of each are presented. In the comparison of the forward and reverse link analysis, forward link is smaller than reverse link. Therefore, the system capacity depends on the forward link rather than the reverse link.

치과용 소와열구 전색제의 조성 용출에 관한 실험적 연구

문현정,임범순,김철위 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

From the recent study, it has raised controversy and concern about an estrogenic chemical, bisphenol-A, which was released from resin-based dental pit and fissure sealants. The purpose of this study was to identify and quantify bisphenol-A and other key leachable components that might be released from dental pit and fissure sealants. Five commercially available light-cured resin-based pit and fissure sealants were studied (CON, PEI, ELI, FSF, and TFI). Specimens were prepared from approximately 50㎕ of each pit and fissure sealants. After curing, specimens were weighed and immersed in two different solution (deionized water and 99.99% ethyl alcohol) for 5 hrs. solutions were analyzed by using High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Mass Spectroscopy (MS), and Ultraviolet Spectrophotometer (US) to detect various leachable components (bisphenol-A ; BPA, triethyleneglycol dimethacrylate ; TEGDMA, bis-glycidyl dimethacrylate ; Bis-GMA). There specimens of each sealant were tested. From the experiment, the following results were obtained : In deionized water, peak with retention time of 2.70 min was identified as TEGDMA and the amount of TEGDMA elution from specimens showed statistically significant difference (p<0.05). In ethyl alcohol, peaks with retention times of 2.70 and 6.04 (4.80) min were identified as TEGDMA and Bis-GMA (UDMA), respectively. TEGDMA eluted from CON, PIF, and ELI showed no statistically significant difference (p>0.05). Also, Bis-GMA eluted from CON, ELI, and FSF showed no statistically significant difference(p>0.05). However bisphenol-A was detected at PIT specimen in ethyl alcohol (retention time : 2.51 min in HPLC and 8.02 min in GC-Mass.). The monomers of pit and fissure sealants were leached within a range of 0.04∼1.94 % of the original weight of the cured sealant for five hours.

政治的 費用의 測定에 관한 實證硏究

鄭文鉉,盧賢燮 부산대학교 상과대학 1991 釜山商大論集 Vol.61 No.-

This paper reviews the positive accounting theory. The positive accounting theory generates an explanation of accounting practice, suggests the importance of contracting costs, and has led to the discovery of some previously unknown empirical regularities. The first objective in this paper is to convey current state of positive accounting theory and to summarize the evidence on systematic empirical regulates in accounting. The second objective is to measure political cost in order to verify the size hypothesis (political cost hypothesis). And, the third objective is to assess the validity of proxy variables of political cost used in positive accounting literature. The size hypothesis is based on the assumption that large firms are more politically sensitive and have relatively larger wealth transfer imposed on them than smaller firm. This costs are called as political costs. This study tests this size hypothesis. The most direct way to transfer corporate asset is via the tax system. And, therefore, explicit taxes (taxes) and implicit taxes quasi-taxes) are one component of political costs borne by firms. This study examines the empirical relationship between corporate income tax rates and proxies of political costs used in positive accounting literatures. In the study, political costs are measured with explicit and implicit taxes reported in the financial statements. Explicit taxes are corporate income taxes and implicit taxes are other taxes and dues, commission, donations and entertainment expenses. The proxy variable of political cost is sales. The results show that the largest firms have lower explicit tax rates and higher implicit tax rates than smaller firms, this relationship is similar over time and across industries. Higher tax rates are observed in the firms above the medium size, lower tax rates of largest firms can be explained by 'diseconomies of scale' in management and 'tax benefits' for the largest firms. This findings suggest that tax components of political cost can be offset by the non-tax component. But, these evidence are resulted only from very restricted data. In the future studies, it is necessary to extend this analysis to alternative sources of data, alternative measures of political costs as well as tax rates.