한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

알레르기 피부 반응 검사시 판독 시간에 따른 팽진의 크기 변화

박장규,윤소영,이웅재,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

There have been several positive criteria for skin prick test, which has been most commonly used in the diagnosis of allergic diseases. Among them, comparing wheal size induced by allergen to that induced by histamine is logical for criteria of skin prick test positivity. We measured the wheal sizes induced by histamine and various causative allergens with five minutes interval, from 5 minutes to 40 minutes, and compared of the time which the wheal size of both reached at peak. The followings were the summary of the findings. 1. Maximal sizes of wheals induced by histamine reached at 12 minutes in average. 2. Maximal sizes of wheals induced by allergens reached at 15 minutes in average. 3. There was no statistical difference between the time of maximal size of wheal induced by histamine and causative allergen.

여드름양 발진에서의 말라쎄지아 포자 검출 빈도에 관한 연구

박장규,이웅재,김연수,서영준,김경호,이증훈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Steroid acne and pityrosporum folliculitis have similar clinical manifestations. So it was not casy to do differential diagnosis of these two diseases. We have tried to find out the different points between these diseases in clinical characteristics, positive rate of the malassezia spores, and their response to antifungal agents. We studied 21 patients with acneiform eruptions which were distinct from acne vulgaris. Patients were divided into two groups by steroid treatment history. Among 21 patients, 6 were administered steroid just before eruption and 15 were free from steroid within 6 months. We have examined malassezia spores with 10% KOH/Parker blue black ink mount from papules, pustules and comedones according to the patients skin lesions. The malassezia spores detected in 5 paticnts(83.3%) in the former and 9 patients(60%) in the latter. In malassezia folliculitis, the frequency of which showed above the (3+) score of malassezia spore under microscopy was higher than in steroid acne. Mean duration of the disease was 70.4 weeks in latter group, which was longer than 5.2 weeks of the former group. And there were some differences between two groups in the distribution of the lesions. Mean treatment duration was same in two groups (4 wks, 3.5 wks). Steroid acne patients would be treated better with antifungal agents than with acne regimens.

一部 樂器의 演奏音에 의한 暴露歷이 聽力에 미치는 影響

박종안,장봉기,이종화,안규동,이영세 순천향대학교 산업의학연구소 1997 순천향산업의학 Vol.3 No.1

This study was carried out to evaluate the effect of playing musical instruments on hearing threshold level from May to October, in 1997. Pure tone audiometric tests was provided to musical instruments playing group of total 117 subjects(Samullnori; 35, military band; 25, symphony orchestra; 46, piano; 11), and reference group of total 7,477 subjects, selected after excluding workers with history of ear disease, of ototoxic drug administration, of noise induced hearing loss at workplace in Pohang industrial area. In addition, noise exposure levels of musical instrument players were assessed by noise dosimetry(exchange rate; 5dB, threshold level; 80dB, criterion level; 90dB), and produced age-adjusted hearing threshold level(=hearing threshold level of musical instrument player - hearing threshold level in same age of normal population group). The age-adjusted hearing threshold levels were analyzed by musician's career. The results were as follows; 1. The hearing threshold level of reference group was revealed more increased as within 4.98dB to 6.89dB at 1 KHz and within 5.26dB to 14.46dB at 4 KHz by ages than "the Standard of Age-adjusted Hearing Loss by Frequency(OSHA)" used for special health examination in the Ministry of Labour. 2. Equivalent continuous sound exposure level (Leq) by the group of instrumentalist was as following; within 104.95 to 112.62dB in samullnori, the highest, within 100.18 to 103.49dB in military band, within 77.00 to 82.74dB in symphony orchestra and 81.54dB in piano, the lowest. Playing maximum sound level by each musical instrument was as following; 122.8dB in Kkwaenggwari, the highest, 122.7dB in Changgo, 121.8dB in Alto saxophone, 115.5dB in Trumpet, 119.2dB in Horn, 112.8dB in Pungmul Buk and Ching, 112.5dB in Clarinet. 3. Average age-adjusted hearing threshold levels of instrumentalists were -0.65±6.38dB in left ear, -0.92±6.59dB in right ear at 1 KHz, and -1.14±12.88dB in left ear, -1.53±12.77dB at 4 KHz, which were better than normal, but the average age-adjusted hearing threshold levels of Samullnori players were 1.23±5.22dB in left ear, 1.94±6.91dB in right ear at 1KHz, and 8.40±15.75dB in left ear. 7.13±14.97dB in right ear at 4KHz, which were worse than normal. 4. Hearing threshold level in Samullnori players was increased with their career at 4 KHz, especially it increased rapidly when the musicians had played over 10years. It showed that there was a significant relationship between hearing threshold level and the career (P<0.01).

백반증의 PUVA치료반응에 관한 연구(제1보)

박장규,성열훈,성범진,김영호,이증훈 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

The authors evaluated response to PUVA therapy in 44 vitiligo petients who did'nt show the spontaneous re-pigmentation. In the responded group to PUVA therapy after systemic administration of 8-methoxy psoralen, average MPD of female patients was 3.4 times higher than males, interestingly. Number of irradiation of UVA was similar between male and female, but total doses of female patients group were about 2 times than males till the first re-pigmented spots were noted. The response to PUVA therapy was quite different according to duration of disease and site of lesion. Therefore, we suppose that it is necessary to consider sex of patient, duration of disease, location of vitiligo before making a plan of PUVA therapy.

국민학교 아동의 체력실태 : 형태와 운동능력 중심으로 Based on Physique and Motor Fitness

朴庄平,李光宰,盧成圭,洪寬伊,李京濟 江原大學校附設體力硏究所 1980 江原大學校附設體育科學硏究所論文集 Vol.- No.5

대전에서 연중 태양광선의 UVA와 UVB양에 대한 조사 (예비보고)

박장규,김경훈,이우재,서기범 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Ultraviolet A(355 nm) and ultraviolet B(290 nm) doses were measured at Taejon from March to September, 1993, on four different weather conditions(clear, relatively clear, relatively cloudy and cloudy). And the results were compared with the doses of Kongju area measured in 1985. The followings were the summary of the findings. 1. UVA(1.98± 0.35 × 10 exp(-3) w/㎠) and UVB(17.62+ 5.72 X 10 exp(-6) w/㎠ doses were peak at noon on clear weather. 2. Average doses of UVA(2.36±0.70 × exp(-3) w/㎠) and UVB(24.28±8.83 × exp(-3) w/㎠) were peak at noon in August on clear weather. 3. The doses of UVA and UVB were influenced by yellow sand, fog and other pollutants. 4. The doses of UVA on clear weather in Daejoen were lower than Kongju about 40%, in contrast those of UVB were not different in statistical values.

The Protein and Isozyme Patterns During in vitro Plant Regeneration of Yooja (Citrus junos Sieb.) and Trifoliate Orange (Poncirus trifoliata Rafin.)

Park,Min-Hee,Jang,Hyun-Kyu,Cha,Young-Ju,Kim,Ho-Bun,Lee,Sook-Young 한국자원식물학회 2002 Plant Resources Vol.5 No.1

In this study, plant regeneration through in vitro culture from plantlet stems of Yooja (C. junos Sieb.) and trifoliate orange (P. trifoliata Rafin.) was attempted to make mass-production system of virus-free plants having the same genotype with mother plant. In order to investigate physiological change depending on the developmental stage of plant regeneration, the changes of total protein, peroxidase and esterase activity and their isozyme patterns as well were examined in 1/2 MS medium. The results are as follows : 1. The MS medium for the optimal callus induction and shoot formation was utilized. The medium was supplemented either with 2,4-D and Kinetin or with BA and NAA. The optimal concentrations were the combination of 1.0mg/ 2,4-D +0.3mg/ Kinetin and 1.0mg BA +0.3mg NAA in callus induction and shoot formation, respectively. 2. For the plant regeneration from somatic embryos, 1/2 MS medium was used with supplements of growth regulators (free, 1.0mg/ IBA +1.0mg/ BA ,0.5mg/ IBA +0.5mg/ BA). Shooting and rooting were the best in the treatment of 0.5mg/ IBA and 0.5mg/ BA combination. 3. The total protein content has a tendency of increase with the developmental stage of embryo, but it was decreased at the plantlet. Also it was the highest at 8 and 6 weeks stage in C. junos Sieb. and P. trioliata Rafin, respectively. In the SDS-PAGE pattern of protein, C. junos Sieb. showed bands of 29.0 and 40kDa at 10 weeks. The 45,66 and 97.4 kDa bands at 10 weeks of culture were shown in P. trifoliata Rafin. 4. The highest esterase activity was shown at the 6 and 8 weeks of culture in C.junos Sieb. and P. trifoliata Rafin.., respectively. 5. Esterase isozyme patterns were shown difference according to the developmental stage. In C. junos Sieb. a new band was observed at pl 7.7 following 4 weeks culture. On the other hand, new bands in P. trifoliata Rafin. were observed at pl 7.5~6.5 following 4 and 6 weeks culture, respectively.

알레르기성질환의 기인항원에 관한 연구

박장규,구자경 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

To fine out the offending allergens in Chungnam province, we performed skin test with 196 diagnostic allergens (Bencard®) in 83 cases of allergic rhinitis and 26 cases of chronic urticaria from August 1982 to August 1986 at the dermatologic OPD. of Chungnam National University Hospital. The results were: 1. The positive reaction of the skin test to the diagnostic allergens in the cases of the allergic rhinitis and chronic urticaria were 91.6% and 80.8%, respectively. 2. In allergic rhinitis, 25% showed the positive reaction to single allergen and 66% to compound allergens and the offending allergens were D. farinae (56.0%), D. pteronyssinus(43.4%), house dust (35.5%), cat fur (30.3%), hay dust (22.3%) in order. 3. In chronic urticaria, 23% showed the positive reaction to single allergen and 58% to compound allergens and the offending allergens were D. farinae (33.3%), mosquito (33.3%), D. pteronyssinus (24%), mixed threshings (24%), maize pollen (24%) in order.

하악에 발생한 과잉치의 치험례 : A CASE REPORT

박정아,양규호,,최남기,김선미,장희숙 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

과잉치는 정상치판(dental lamina)의 과도한 증식이 결과로 발생되어, 가족적 성향을 보이며, 쇄골두개이형성(Cleidocranial dysplasia), Gardner 증후군 등의 여러 질환과 관련되어 나타나기도 한다. 그 빈도는 유치열에서 0.3~0.8%, 영구치열에서 1.0~3.5% 이고, 남성에서 호발되며(2:1), 상악에서 더 많이 발생한다(9:1). 상악에서는 mesiodens라고 불리는 중절치 사이의 위치가 가장 흔한 부위이고, 그 다음은 fourth molar와 측절치 부위이다. 하악에서는 소구치 부위가 가장 흔한 부위이고 전치부위에서는 약 2%로 매우 드물게 발생한다. 과잉치의 만기 잔존은 치간 이개, 인접한 치아의 맹출 장애, 치근 흡수 등을 야기하고 과잉치와 관련되어 함치성 낭종이 발생될 수 있으므로 조기진단과 적절한 치료가 중요하다. 본 두 증례는 비교적 드물게 나타나는 하악에 발생한 과잉치로, 하악 전치부와 소구치부에 발생한 과잉치를 발거하고 교정치료를 시행하여 양호한 결과를 얻었기에 보고하는 바이다. Supernumerary tooth was resulted from excessive proliferation of dental lamina and associated with familial tendency and a congenital syndrome such as Cleidocranial dysostosis or Gardner's syndrome. Incidence reports identify a range of 0.3~0.8% in primary dentition. 1.0~3.5% in permanent dentistion with males being affected twice as frequently as females. maxilla nine times as frequently as mandible. The most common supernumeraty tooth is the mesiodens, which located between the maxillary central incisors, and the next common site is the fourth molar and lateral incisors. Supernumerary teeth are uncommon in the mendible, but premolars are the most common supernumerary teeth and occurrence is very rare in the incisor region of the mandible of possibility of diastema and cruption failure displacement. rotation of the associated permanent teeth, root resorption and dentigerous cyst with presence of the supernumerary teeth. In this two case, one supernumerary tooth located in the mandibular incisor region, the other supernumerary tooth located in premolar region. We could get normal alignment of mandibular dentition by extraction and orthodontic treatment.