사다리꼴 핀에 대한 해석적 방법과 실험의 비교

조철현,한영민,강형석 江原大學校 産業技術硏究所 2005 産業技術硏究 Vol.25 No.A

A trapezoidal fin is analyzed by using one-dimensional analytic method. For two boundary conditions, the heat transfer rate is given instead of specified temperature at the fin base and heat conduction into the fin tip is equal to heat convection from the tip. Temperatures at three different points within the trapezoidal fin are measured by using experimental apparatus. A comparison of the temperature between one-dimensional analytic method and experimentation is made as a function of dimensionless fin length under both free convection and forced convection conditions. The ratio of heat loss from the fin tip surface to that through the fin base is presented as a function of dimensionless fin length and Biot number. One of results shows that the relative error increases as the air velocity increases for forced convection conditions.

黃菊과 黑薔薇를 이용한 기능성 花茶 개발 Ⅱ.花茶의 품질특성

조경숙,서정근,정형석 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.2

본 연구는 화차의 비율별 제조공정에 따른 화차의 관능적 품질을 평가하기 위해서 수행되었다. 녹차와 꽃의 시료에 대한 색도중 L, a, b값은 녹차가 29.93, -8.24, 9.27로 녹색을, 황국은 47.20, -1.69, 29.12로 밝은 황색을, 흑장미는 37.18, 4.47, 4.12로 흑적색을 띠웠다. 색상과 채도는 황국이 -17.23과 29.17로 가장 높아 색상이 가장 밝고 선명하였으며, 흑장미는 0.92와 6.08로 색상이 어둡고 둔탁한 적색을 띠워 녹차에 꽃을 혼합할 경우 시각적으로 황국은 쉽게 구별이 되었으며 흑장미는 쉽게 구별되지 않았다. 황국 화차는 꽃의 비율이 증가할수록 국화향, 상쾌하고 개운한 단맛의 증가와 더불어 떫은 맛이 감소하였으나, 혼합비율이 9:2 이상일 경우에는 쑥냄새와 같은 강한 국화향이 증가하여 녹차 고유의 향은 거의 상쇄되는 경향이었다. 장미 화차는 장미꽃이 증가할수록 시큼한 장미향이 강하게 증가하였고, 탄닌성분이 많아 떫고 텁텁한 맛과 시큼한 맛이 강한 것으로 평가되었다. 녹차에 알맞은 꽃의 혼합율은 9:1이하의 비율로 혼합했을 때 황국과 흑장미의 꽃잎색이 녹차와 어울려 전체적인 조화성과 풍미, 시각적 아름다움을 증가시켰다. 녹차에 꽃을 혼합한 화차는 녹차 단일의 차보다는 시각적 즐거움과 독특한 방향성이 부가되어 맛과 향이 풍부한 기능성 꽃차 개발에 좋은 재료로 평가되었다. This experiment was carried out to investigate the effect of mixed ratio on the sensory evaluation in manufacture of functional flower tea. Among the chromaticity about green-tea and material flower, the amount of L, a, b of green tea was 29.93, -8.24, 9.27 with green, the amount of a yellow chrysanthemum(C.indicum) was 47.20, -1.69, 29.12 with bright yellow, the amount of a black rose(Rosa hybrida)is 37.18, 4.47, 4.12 with dark red. The yellow chrysanthemum has brightest and most distinct color with -17.23 hue and 29.17 chrome value, but the black rose has dark dead red color with 0.29 hue 6.08 chrome value. When the yellow chrysanthemum mixed with green tea, it was easily distinguished with naked eye. But the black rose was not distinguishable easily. As the retio increase, the yellow chrysanthemum tea has more chrysanthemum scent, increase of refreshing and relieved sweetness, and less astringent taste. If the mixed rate was over 9:2, original scent of green tea was almost offset with strong chrysanthemum scent like mugwort's. As the ratio increase, the rose tea has strongly increased sourish, and because of the tannin it was appraised strong astringent, unpleasant, sourish taste. The best-mixed ratio of green tea and flower is 9:1. When it mixed at this ratio, the yellow chrysanthemum and petal color of black rose was well matched with green tea, and the tea has general harmony and flavor and it is visually beautiful. Flower tea, green tea from flower, has added visually joy and unique fragrance, it was valued as fine material for rich taste and scent technical tea development.

탈진적 수영운동과 Selenium투여가 혈액 내 지질과산화물과 항산화효소 활성도에 미치는 영향

조형숙,김문희 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.4

This study investigates the blood MDA(malondialdehyde), SOD(superoxide dismutase), CAT(catalase) and GPX(glutathione peroxidase) activity in response to acute exhaustive swimming and selenium administration in rats. The animals in this study were chosen fourty-eight rats (Sprague -Dawley, male, 10 weeks, 300g), they were separated selenium group and placebo group. Selenium (sodium selenite, 2ppm/300g) solved in distilled water 1.0ml was administrated to them using by zoned needle at before 10 minutes swimming. The blood sampling time of two groups were three times (rest, after 30min swimming, exhaustion), 6ml blood were collected by abdominal aorta after the ethyl ether inhalation. The blood samples were centrifuged 3,000rpm for serum CAT, plasma SOD, plasma GPX and blood MDA activities analyzing. The statistical method was used by 2-way ANOVA. In summary, selenium, as a component of GPX, as a lipid soluble free radical scavenger serve and biological antioxidant defense system. selenium supplementation and acute exhaustive swimming within blood in rats enzyme activities (SOD,CAT,GPX) increase but MDA decrease. Also, our findings indicate that selenium have a positive effects to prevent the exercise induced increase in oxidative stress. Acute exhaustive swimming the improved of the body's defense capacities against free radical generation, likely as a result of adaptable increase in activities of antioxidant enzyme system.

重化學工業機械의 國産化方案에 關한 硏究 : 特히 窯業에 있어서의 燒成爐, 粉碎機, 排風機, 冷却機, 電氣集마器 自動枰量供給器 等의 製作을 目的으로

趙哲衡,朴碩喆,丁太權,宋鐵,桭達福,金基玉,朴煥奎,趙煥從,朴善鐘,金種一,李茂錫 朝鮮大學校 1977 綜合論文集 Vol.1977 No.-

This is to investigate the posibility of home manufacturing of heavy chemical industry machines, such as rotary kiln, crusher, blower, cooler, electrostatic precipitator and weighing feeder of cement plant. It is concluded that even though we can not make all of them (some of them are made now and some others are going to be made in the near future, some of them are made whole and some others are made partially), we can build or export the cement plant by importing the important machines which we can not make now and by substituting them with ours gradually.

유한세프라딘 캅셀(세프라딘 500 mg)에 대한 브로드세프 캅셀의 생물학적 동등성

조혜영,이석,강현아,오인준,임동구,문재동,이용복 전남대학교 약품개발연구소 2002 약품개발연구지 Vol.11 No.-

Cepharadine is a first generation cephalosporin and has broad spectrum antibacterial activity against gram-positive and gram-negative microorganisms, through inhibition of bacterial cell wall synthesis. Cephradine is useful for treatment of infections of the urinary and respiratory tract, skin and soft tissues. The purpose of the present study was to evaluate the bioequinalence of two cepharadine capsules, Cefradine Yuhan (Yuhan Corporation) and Broadcef (Ilsung Pharmaceuticals Co. Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The cephradine release from the two cephradine capsules ?? was tested using KP Ⅶ Apparatus Ⅱ method with various different kinds of dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty normal male volunteers, 23.10±2.90 years in age and 67.69±8.04 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After one capsule containing 500 ㎎ as cephradine was orally administered, blood was taken at predetermined time intervals and the concentrations of cepharadine in serum were determined using HPLC method with UV detector. The dissolution profiles of two cephradine capsules were very similar at all dissolution media. Besides, the phaemacokinetic parameters such as AUC_t, C_max and T_max were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_t and C_max and untransformed T_max. The results showed that the differences in AUC_t, C_max and T_max between two capsules based on the Cefradine Yuhan were -2.87%, -0.96% and -4.85%, respectively. There were no sequence effects between two capsules in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.93)∼log(1.02) and log(0.88)∼log(1.13) for AUC_t, and C_max, respectively). the 90% confidence interval using untransformed data was within ±20% (e.g., -17.54∼7.78 for T_max). All parameters met the criteria of KFDA guideline for bioequivalence, indicating that Broadcef capsule is bioequivalent to Cefradine Yuhan capsule.

탄수화물에서 syn-과 anti-2, 3-디히드록시 알데히드의 합성 : L-Factor와 Muricatacin의 합성

강석구,조현성,심형수 성균관대학교 기초과학연구소 1993 論文集 Vol.44 No.1

천연물합성에 있어서 합성중간체로서 유용한 광학활성의 O-보호된 syn-과 anti-2, 3-디히드록시 알데히드의 네 가지 입체이성질체들을 쉽게 구할 수 있는 D-글루코스나 D-크실로스에서 유도된 푸라노스를 변형시켜 합성하였다. 예컨대 불포화 퓨라노스계의 이중결합에 수소화붕소 첨가반응-산화반응에 의해 입체선택적으로 히드록시퓨라노스를 얻고 이를 O-베질화후 탈아세톤화, 산화성절단반응에 의해 (2S, 3S)-3-포르옥시-2-벤질옥시알칸알을 얻었으며 그 외 (2S, 3R)-, (2R, 3S)-, (2R, 3R)-디히드록시알칸알을 얻었다. 이러한 중간체들을 이용하여 L-factor와 muricatacin을 합성하였다. Four stereosiomers of optically active O-protected syn- and anti-2, 3-dihydroxy aldehydes, chiral synthons for natutal product synthesis, were synthesized from readily avilable D-glucose and E-Xylose. (2S, 3S)-3-Formylosy-2-benzylxoy alkanals were synthesized by stereoselective hydroboration of the unsaturated furanoses followed by O-benzylation, deprotection, and oxidative cleavage. (2S, 3R)-, (2R, 3S)-, and (2R, 3R)-Dihydroxy alkanals were also synthesized. Using these chiral synthons, (4R, 5S)-(-)- and (4S, 5S)-(+)-L-factors, the proposed autoregulators from Strpiomyces griseus and muricatacin, a biologically active constituent from the seeds of Annona muricata L. were synthesized.

탄수화물에서 광학활성 중간체 O-보호된 (S)-와 (R)-3-히드록시 알데히드의 합성

강석구,조현성,심형수 성균관대학교 기초과학연구소 1993 論文集 Vol.44 No.1

탄수화물로부터 유도된 불포화 퓨라노스 고리계를 입체 선택적인 수소화 반응에 의해 chiral synthon인 광학활성의 (S)-3-포르밀옥시 알데히드를 합성하였고, 탄수화물에서 유도된 3-히드록시 퓨라노스를 Barton-McCombie의 deoxygenation반응에 의해 (R)-3-포르밀옥시 알데히드를 합성하였다. (S)-e-Formyloxyaldehydes, chiral synthons for natural products, were synthesized via highly stereoselective hydrogenation of the unsaturated furanose ring system derived from D-glucose or D-xylose. Alternatively, (R)-3-formyloxyaldehydes were prepared via deoxygenation of 3-hydroxyfuranoses.

대황황련해독탕의 항고지혈증 작용

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

Whangryunhaedok-Tang (WT) is formulated with Coptidis Rhizoma, Phellodendri Cortex, Scutellariae Radix and Gardeniae Fructus, and Daewhang-whangryunhaedok-Tang (DWT) is made by the combination of Rhei Rhizoma, a wellknown anticostipation drug in WT. Therefore, DWT has been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by corn oil and high cholesterol-diet. Oral administration of DWT significantly inhibited the increase of serum triglyceride and LDL-cholesterol levels, and the decrease of serum HDL-cholesterol levels in hyperlipidemic rats induced by corn oil. Also, oral administration of DWT significantly prevented the increase of serum total cholesterol, triglyceride and LDL-cholesterol, and liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that DWT is effective for the treatment of hyperlipidemia.

대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

먹는 물에서의 비소 검출에 관한 연구 : ICP-USN법과 ICP-VGA법의 비교 Comparison ICP-USN method ICP-VGA method

박경선,김형석,조인성 慶熙大學校 地球環境硏究所 1999 지구환경논문집 Vol.10 No.-

Abstract The analysis of arsenic in drinking water with ICP-USN method and ICP-VGA method was studied. In USN method, wavelength of 193.696nm was used and in VGA method, 228.812nm was used. The values of arsenic of same sample in each method, MDL, RPD, recovery, accuracy and precision were studied. The values of 14 sample of drinking water were within 0.05ppm or were not detected. But in one sample high value of 0.044ppm was detected. MDL of USN was 0.013ppm and MDL of VGA was 0.0004ppm. This results showed lower MDL of VGA but RPD of USN was better than VGA. Recovery of two methods was same, but accuracy and precision of USN were better than VGA. Therefore ICP-VGA method could be used according to this result(MDL) when arsenic trace element detection in drinking water should be achieved.