다공성 미립 담체에서의 동물세포 성장 및 부착 속도와 바이러스 백신의 생산

임현수 麗水水産大學校 産業技術硏究所 1996 産業基術硏究所 論文集 Vol.5 No.-

본 실험실에서 개발한 젤라틴 다공성 담체(K-beads)와 상업용 다공성 담체인Cultispher-G를 이용하여 Chinese Hamster Overy(CHO)세포와 African Green Monkey Kidney(Vero)세포에 대한 세포의 담체 부착 속도와 성장성을 살펴보았다. 양 세포주의 담체에 대한 초기 부착 속도는 시간에 따라 일차 함수 관계를 보였으며, 부착율은 접종 세포량의 90%에 달했다. Vero세포의 K-beads에서의 성장은 140시간 배양후 최종농도가 5.6×??cells/ml이었으나, Cultispher-G에서는 세포의 초기 성장이 늦고 최종 세포 농도도 3.5×??cells/ml로 나타났다. Vero세포의 성장이 최고농도에 도달직전에 Vesicular Stomatitis Virus(VSV)를 0.1MOI(Multiplicity of Infection)로 접종하여 이틀 뒤 그 생성농도를 살펴본 결과 K-beads에서 5.7×??pfu/ml로 Cultispher-G 보다 높게 나타났다. 결과적으로 K-beads가 세포의 고농도 배양 및 백신의 고농도 생산에 적합한 담체임을 확인하였다.

PDT(Photodynamic Therapy) 레이저 시스템의 방사모드 제어 장치 개발

임현수 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

A new control device for Photodynamic Therapy(PDT) laser system is proposed in this paper. The accuracy measurement of light dose in cancer therapy using the laser is very important role, so the laser output require that high speed and statistical output control. The developed control device is possible to accurate and statistical control output using constant current control. The final beam power is 300mW max. at the 600nm wavelength. The laser power supply was designed to protect the resonator from the over-current and in rush-current etc. The experimental result show that laser beam power increase linearly from 10mW to 300mW for input current. The radiation type are CW, LONG PULSE, SHORT PULSE, SUPER PULSE, BURST PULSE. We can adjust the exposure time from several milli-second to several minute, and according to this experiment, we can make the variable type of power, radiation, exposure time that requested by the PDT system.

하악골 비대칭과 측모두부방사선사진상 이중영상 간의 관계

임현대,한경수 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

This study was performed to investigate the affecting factors to double images on the cephalometric radiograph. For this study, 28 patients with temporomandibular disorders and 31 healthy dental students without any signs and symptoms of temporomandibular disorders were selected, and the cephalometric and the panoramic radiographs were taken. The observed and measured points related to double images on the cephalometric radiograph were Or, Go1, Go2, Go3, and C1. Both mandibular ramus height were measured on the panoramic radiograph. Natural head and body posture in the frontal and the sagittal plane were observed with CROM?? and with posture measuring board, with regard to several parameters. The data obtained were processed with SPSS Windows?? program. The result were as follows : 1. There were no correlation between the difference of both mandibular ramus height and the length of cephalometric double image at observed points. 2. The length of double image in Or and Go2 in the subjects with more headtilt in frontal plane(≥2˚ )were different from the subjects with less headtilt(≤1˚ ). 3. Difference of angulation of both sternocleidomastoid muscles in sagittal plane did not affect the length of cephalometric double image in all the measured points. 4. There were negative correlation between the length of cephalometric double image in Go1 and C1 and canthotragus angle. 5. There were no correlation between the length of cephalometric double image and the frontal parameters, but there were significant correlation between the length of double image and the sagittal parameters such as sagittal angle, degree of forward head posture(FHP), and canthotragus angle.

철강업체와 용접봉 제조업체에 근무하는 생산직 근로자의 직업성 요통 유병률과 관련 요인

임현술,김수근,김덕수,김두희,이종민,김양호 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

A cross-sectional study was conducted for detecting the risk factors and to propose an effective control program for occupational low back pain. The subjects were 1,665 male production workers employed at a steel factory and a welding material manufacturing factory. The data were collected by a self-reported questionnaire and a medical examination with a rehabilitation specialist for ten days in September, 1997. The contents of the questionnaire were as follows: general characteristics, physical characteristics, employment status, type of work, working environment and the experience of low back pain. The number of cases with symptoms of occupational low back pain were 321, so the point prevalence was 19.3 persons/100 persons. The number of cases with a history of occupational low back pain for one year were 554, so the one year period prevalence was 33.3 persons/100 persons. The point and one year period prevalences of occupational low back pain showed no significant differences in age, marital status, educational level and body mass index. The point and one year period prevalences of occupational low back pain showed no significant differences in alcohol drinking, smoking, stretching exercise and regular exercise. The point and one year period prevalences of occupational low back pain were significantly higher in the unsatisfied group that the satisfied group (p<0.01). However, no significant differences were found among tenures and shift work. The point and one year period prevalences of occupational low back pain were significantly higher in the lifting of heavy materials group than the nonlifting group(p<0.01). However, no significant differences were found among posture of the waist and the working posture. Through the multivariate logistic regression, significantly associated factors with occupational low back pain were found to be dissatisfaction with job (point prevalence: OR=1.78, 95% CI: 1.21-2.61: one year prevalence : OR=1.76, 95% CI: 1.26-2.47), lifting of heavy materials(point prevalence OR=1.94 95% CI : 1.44-2.61; one year prevalence: OR=2.17, 95% CI : 1.70-2.77) and tenure (point prevalence : OR=1.03, 95% CI : 1.01-1.06; one year prevalence : OR=1.02, 95% CI : 1.00-1.05).

Salmonellosis에 대한 細菌學的硏究

林賢植,朴京洙,朴悅 조선의대 1983 The Medical Journal of Chosun University Vol.8 No.1

채용시 건강진단에서 요ㆍ천추부 단순 방사선 검사의 평가

임현술,김수군,김덕수,이현경,최대섭 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : A study was conducted for investigating the status of simple X-rays on lumbo-sacral regions at pre-employment health examination and analysing the effectiveness of simple X-rays on lumbo-sacral regions. Methods : The study data were pre-employment health examination data in a university hospital from Jan 3, 1993 through October of 1997. And, 97 newly employed workers who claimed no low back pawn at pre-employment health examination of a certain company were follow-up survey about low back pain and related factors in April, 1995 and October of 1997. The data were collected by a self-reported questionnaire and a medical examination with a rehabilitation specialist. Results : 1. Taking the simple X-rays on lumbo-sacral regions was 1,591 workers (10.5%) among 15,166 pre-employment health examination from Jan 3, 1993 through October of 1997. And yearly application rates of these X-ray tests have been significantly statistical increasing (p〈0.01). 2. The abnormal findings of simple X-rays on lumbo-sacral regions at pre-employment health examination were 40 workers. But, there was not significantly statistical difference between normal and abnormal group for the complaint rate of low back pain. 3. The number of case with symptoms of low back pain at the follow-up survey were 46, so The incidence density was 37.1 persons/ 100 person-years. And the incidence density was not significantly statistical difference between normal and abnormal group of simple X-rays on lumbo-sacral regions. 4. Through the multivariate logistic regression, significantly associated factors with low back Pain were found to be tenure(OR=0.36, 95%CI : 0.17-0.79), lifting of heavy materials (OR=5.86, 95%CI : 1.58-21.74) . Conclusion : The simple X-rays on lumbo-sacral regions at pre-employment health examination is required further research for utilizing pre-employment health examination according to above results.

효소적 방법으로 제조된 키토산 올리고당의 첨가에 따른 김치의 숙성 및 저장 기간 연장에 관한 연구

임현수,김진만,유은정,최명락 여수대학교 1998 論文集 Vol.13 No.2

효소로 처리된 키토산 올리고당의 첨가에 의한 김치의 숙성 기간 연장 효과를 알아보기 위하여 배추김치에는 0.2-0.4%, 2일째에 0.4%를 첨가하여 20℃에서 10일간 관찰한 결과 0.2% 첨가시 대조군에 비해 2일, 0.4% 첨가시는 4일, 2일째에 0.4%를 첨가한 경우는 8일 이후로 연장 효과가 2-4배 있었으며, 0.4% 이상에서는 미생물 생육자체가 억제되므로 풍미 및 유기산의 생성을 고려할 때 2일째 첨가된 0.4%가 젖산균의 수는 어느정도 유지하면서 stationary phage를 연장시킴으로서 더 좋은 결과를 나타냈다. 갓 김치의 경우 0.1%-0.5% 첨가시 대조군에 비해 1.2-1.4배의 연장 효과가 있어서 배추 김치에 비해서는 낮은 효과를 나타냈다. 따라서, 효소로 처리된 키토산 올리고당의 첨가에 의해 배추 김치는 2-4배의 연장 효과, 갓김치는 1.2-1.4배의 연장 효과를 나타내어 미생물 증식 억제에 의한 김치의 숙성 및 저장 기간 연장 효과를 기대할 수 있었다. To prolong the fermenting and preservation period of Kimchi, chitosanoligosaccharide was prepared by chitosanase. Various concentrations of chitosanoligosaccharide were added into Chinese cabbage Kimchi and Gat Kimchi. Chinese cabbage Kimchi was formulated with various chitosanoligosaccharide concentrations(0.2-0.4%) and fermented at 20℃. And Gat Kimchi was prepared with various chitosanoligosaccharide(0.1-0.5%) concentrations during 26 days at 4℃. In this results, the fermentation period was increased 2-2.5 and 1.2-1.4 folds more than control(0% of chitosanoligosaccharide) for Chinese cabbage Kimchi and Gat Kimchi, respectively. Conclusively, adding of chitosanoligosaccharide into Kimchi significantly prolonged the fermentation and preservation period.

대중국의 재해석 : 연극과 영화 <8명의 여인들 Huit emmes> 의 비교 연구

임수현 서울여자대학교 2011 인문논총 Vol.21 No.-

본 논문은 이러한 인식을 토대로 하여, 토마의 연극 <8명의 여인들> 이 지닌 연극성과 대중극으로서 면모가 오종과 스타 여배우들의 영화 <8명의 여인들> 을 통해 어떤 식으로 복합성과 다양성을 지닌 텍스트로 재탄생하게 되는지를 살펴보고자 한다. 연극과 영화라는 매체에 대한 비교는 보다 전문적이고 미학적인 연구가 필요하겠지만, 본 논문은 <8명의 여인들> 한 작품에 국한시켜 각색을 통해 원본의 장점을 강화 하면서도 한계를 뛰어넘는 양상들을 살펴보는 데 초점을 맞추게 될것이다. Notre etude a pour objectif de comparer le théâtre "HuitFemmes" de Robert Thomas avec son adaptation cinématographique de FranÇois Ozon, pour on reconnaître les aspects spécifiques de ce texte et les modalités do sa nouvelle interprétation. Appartenant á la tradition du théâtre de boulevard des années soixante, Thomas met on scéne, dans cette piéce, une famille bourgeoise en crise causée par la mort du “pére” de la maison. Il s’agit d’une comédie policiére, une enquête à suspense menée par les members de la famille, les ‘huit femmes’. les'huit femmes'. L'originalité de cette piéce semble résulte de deux choses, d'une part de l’intrigue 'bien faite' avec nombreux coups de théâtre, a la Agatha Christie ou à la Alfred Hitchcock, et d'autre part, des figures originales des personnages feminins, qui s’impllquent entre elles, chacune se révélant une feminite particuliere.

단시간 푸리에 해석에 의한 근전신호 해석

임현수,이병철 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

In this paper, a method of the measument the degree of the musule fatigue by short Time Fourier Analysis of the EMG signals from human biceps in the action state is proposed. For this purpose, fatigue state and recovery state of 10 persons EMG signals are sampled. And then spectrum centroids are analyzed with respect to the change of sample time window. As result of 10 persons experiment, we know that person A is most good recovery state.

원자력 발전소 근로자에서 업무상 질병으로 인정받은 급성 골수성 백혈병 1예

임현술,정해관,김수근,박병찬,이관 약업신문사 1983 의약정보 Vol.9 No.-