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      • The CharacterIzation of ornithine decarboxylase (CaOCD1) and ascorbate peroxidase (CaAPX1) genes in TMV-resistant hot pepper

        Yoo, Tae Hyoung,Park, Chang-Jin,Han, Sang-Je,Lee, Gil-Je,Shin, Ryoung,Yun, Ji-Hyun,Kim, Ki-Jeong,Peak, Kyung-Hee 충북대학교 한국과학재단 지정 첨단원예기술개발 연구센터 2002 연구보고서 Vol.6 No.-

        CaAPX1와 CaODC1의 발현 양상과 발현양을 조사하고 병저항성에 관련하여 각가의 유전자가 작용하는 기능을 알아보기 위해 담배에 형질전환체를 만들고 있는 중으로 현재 CaODC1이 형질전환체로 생산되었다. Capsicum annuum L. is infected by a number of viruses including tobacco mosaic virus (TMV). To study the defense-related genes induced against TMV in hot pepper, the leaves of pepper plant which is susceptible to P1.2 but resistant to P0 pathotype of TMV were inoculated with TMV-P0, and genes specifically up- or down-regulated during hypersensitive response were isolated by differential screening. Of those, two cDNA clones, CaODC1 and CaAPX1, were selected for further study. The CaODC1 cDNA clone putatively encoding a polypeptide of ornithine decaroboxylase and the CaAPX1 of ascorbate peroxidase were isolated. The full-length cDNAs, which is 1433 bp for CaODC1 and 972 bp for CaAPX1, contain the open reading frame of 436 and 250-amino aced residues, respectively. The response of these genes upon other pathogen infection was also examined by the bacterial pathogen (Xanthomonas compestris pv. vesicatoria race 3) inoculation. Both genes were induced in a hot pepper (C. annuum cv. ECW 20R) resistnat to this bacterial pathogen but not in a susceptible hot pepper (C. annuum cv. ECW). Especially, the transcript level of CaODC1 gene was increased rapidly in the early time after the inoculation. The result suggests possible role(s) for CaAPX1 and CaODC1 genes in plant defense against pathogens including a virus.

      • SCOPUSKCI등재

        Synthesis of CaS:Eu<sup>2+</sup> Phosphor by using a Sealing Vessel and its Photoluminescence Properties

        Yoo, Hyoung-Sun,Park, Bong-Je,Kang, Jong-Hyuk,Im, Won-Bin,Jeon, Duk-Young The Korean Institute of Electrical and Electronic 2007 Transactions on Electrical and Electronic Material Vol.8 No.6

        We have synthesized $CaS:Eu^{2+}$ phosphor by using a sealing vessel and evaluated its photoluminescence properties. The method using a sealing vessel is simple and economical in comparison with other methods reported up to date. As an activator concentration was increased from 0.1 mol% to 4 mol%, the main emission wavelength of the phosphor was increased from 642 nm to 651 nm due to the crystal field splitting of 5d levels of $Eu^{2+}$ ion. Although the same amount of $Eu_2O_3$ was used, the concentration of the activator ions, which were reduced from $Eu^{3+}\;to\;Eu^{2+}$ and substituted $Ca^{2+}$ ions, was increased with increase of firing temperature. Therefore, the main emission wavelength was also. shifted from 645 nm to 651 nm with increase of firing temperature from $1100^{\circ}C\;to\;1300^{\circ}C$. The critical distance($R_{c1}=20.65\;{\AA}$) between $Eu^{2+}$ ions calculated from the critical concentration was well matched with that($R_{c2}=19.17\;{\AA}$) calculated from the Dexter formula.

      • KCI등재

        Synthesis of CaS:Eu2+ Phosphor by using a Sealing Vessel and its Photoluminescence Properties

        Hyoung Sun Yoo,Bong Je Park,Jong Hyuk Kang,Won Bin Im,전덕영 한국전기전자재료학회 2007 Transactions on Electrical and Electronic Material Vol.8 No.6

        We have synthesized CaS:Eu2+ phosphor by using a sealing vessel and evaluated its photoluminescence properties. The method using a sealing vessel is simple and economical in comparison with other methods reported up to date. As an activator concentration was increased from 0.1 mol% to 4 mol%, the main emission wavelength of the phosphor was increased from 642 nm to 651 nm due to the crystal field splitting of 5d levels of Eu2+ ion. Although the same amount of Eu2O3 was used, the concentration of the activator ions, which were reduced from Eu3+ to Eu2+ and substituted Ca2+ ions, was increased with increase of firing temperature. Therefore, the main emission wavelength was also shifted from 645 nm to 651 nm with increase of firing temperature from 1100 °C to 1300 °C. The critical distance (Rc1 = 20.65 Å) between Eu2+ ions calculated from the critical concentration was well matched with that (Rc2 = 19.17 Å) calculated from the Dexter formula.

      • 일부 대학생의 담배가격 인상과 금연의지

        유제윤 ( Je Yoon Yoo ),이주형 ( Ju Hyoung Lee ) 전북대학교 의과학연구소 2004 全北醫大論文集 Vol.28 No.2

        본 연구는 일부 지역 대학생들을 대상으로 담배가격 인상에 따른 금연의지 및 관련요인을 파악하고자, 전라북도내 위치한 2개 종합대학 809명의 학생들을 대상으로 2004년 9월 15일부터 10월 10일까지 구조화된 설문지를 이용하여 조사를 실시한 결과는 다음과 같았다. 흡연율은 남성 24.5%, 여성 1.3%이었으며, 흡연자 109명의 79.8%가 담배가격이 인상되면 금연을 시도할 의지가 있는 것으로 조사되었다. 로지스틱 회귀분석 결과 운동을 1주에 3회 이상 실시하는 경우 (OR=3.22, 95% CI 1.05, 9.81)와 현재 금연을 고려하고 있는 경우(OR=7.10, 95% CI 2.35, 21.43) 담배가격 인상이 따른 금연계획에 실제 영향을 주는 것으로 조사되었다. 이상의 결과 운동과 현재 금연계획 여부만이 여향을 미치는 것으로 조사되어, 금연의지 여부에 영향을 주는 것은 담배 가격인상에 대한 경제적 부담이라기보다 평소 금연을 할 의지와 건강에 대한 개인의 가치인 것으로 생각된다. Objective : The purpose of this study was to investigate the associated factors between raising of tobacco price and willingness to quit smoking among university students. Methods : Total 809 students in an Jeollabuk-do`s two universities participated in this study. During the period from Sep 16, 2004 to Oct 10, they was answered the structural questionnaire on smoking, exercise and drinking status and sociopsychological factors. Results : The smoking rate of men was 24.5% and women 1.3%. The 87(79.8%) of 109 smokers would quit smoking if price of tobacco raised, and the factors that affects cessation of smoking was major, execise, allowance, opinion for raising the price of cigarette, self efficacy and current plan to quit smoking. But, exercise more than 3 times a week(OR=3.22, 95% confidence interval 1.05, 9.81) and current plan to quit smoking(OR=7.10, 95% confidence interval 2.35, 21.43) were closely associated with willingness to quit smoking by multivariate logistic regression. Conclusions : The major factors affecting the willingness to quit smoking were not economical burden but current willingness to quit and personal values of health.

      • SCOPUSKCI등재
      • Portable multi-parameter electrical impedance tomography for sleep apnea and hypoventilation monitoring: feasibility study

        Lee, Min Hyoung,Jang, Geuk Young,Kim, Young Eun,Yoo, Pil Joong,Wi, Hun,Oh, Tong In,Woo, Eung Je IOP 2018 Physiological measurement Vol.39 No.12

        <P> <I>Objective</I>: Quantitative ventilation monitoring and respiratory event detection are needed for the diagnosis of sleep apnea and hypoventilation. We developed a portable device with a chest belt, nasal cannula and finger sensor to continuously acquire multi-channel signals including tidal volume, nasal pressure, respiratory effort, body position, snoring sound, ECG and SpO<SUB>2</SUB>. The unique feature of the device is the continuous tidal volume signal obtained from real-time lung ventilation images produced by the electrical impedance tomography (EIT) technique. <I>Approach</I>: The chest belt includes 16 electrodes for real-time time-difference EIT imaging and ECG data acquisitions. It also includes a microphone, accelerometer, gyroscope, magnetometer and pressure sensor to acquire, respectively, snoring sound, respiratory effort, body position and nasal pressure signals. A separate finger sensor is used to measure SpO<SUB>2</SUB>. The minute ventilation signal is derived from the tidal volume signal and respiration rate. <I>Main results</I>: The experimental results from a conductivity phantom, four swine subjects and one human volunteer show that the developed multi-parameter EIT device could supplement existing polysomnography (PSG) and home sleep test (HST) devices to improve the accuracy of sleep apnea diagnosis. The portable device could be also used as a new tool for continuous hypoventilation monitoring of non-intubated patients with respiratory depression. <I>Significance</I>: Following the feasibility study in this paper, future validation studies in comparison with in-lab PSG, HST and end-tidal CO<SUB>2</SUB> devices are suggested to find its clinical efficacy as a sleep apnea diagnosis and hypoventilation monitoring tool.</P>

      • SCOPUSKCI등재

        부신 우연종에서 F-18 FDG PET/CT의 유용성: 악성 종양 환자에서 부신 전이의 감별진단

        이홍제 ( Hong Je Lee ),송봉일 ( Bong Il Song ),강성민 ( Sung Min Kang ),정신영 ( Shin Young Jeong ),서지형 ( Ji Hyoung Seo ),이상우 ( Sang Woo Lee ),유정수 ( Jeong Soo Yoo ),안병철 ( Byeong Cheol Ahn ),이재태 ( Jae Tae Lee ) 대한핵의학회 2009 핵의학 분자영상 Vol.43 No.5

        목적: 악성 종양 환자의 F-18 FDG PET/CT에서 우연히 발견된 부신 종양의 특성에 대해 알아보고 양성 및 악성 부신 종양을 감별하는 데 있어서 F-18 FDG PET/CT의 진단 능력에 대해 평가해 보았다. 대상 및 방법: 2005년 3월부터 2008년 8월까지 시행한 F-18 FDG PET/CT에서 우연히 부신 종양이 발견된 75명의 악성 종양 환자들(89개의 부신 종양)을 대상으로 하였다. 평균 연령은 60.8±10.2 (35-87)세였으며, 남자는 46명, 여자는 29명이었다. 정량 분석을 위해 89개의 부신 종양의 장경(cm), HU, SUVmax, SUVratio를 각각 측정하였다. 부신 종양의 SUVmax를 간의 8번 분절의 SUVmax인 SUVliver로 나눈 값을 SUVratio로 하였다. 부신 종양은 조직학적 확진, 방사선학적 평가(HU<0: 양성), 임상적 판단에 따라 최종 진단하였다. 결과: 양성과 악성 부신 종양을 감별하는데 크기, HU, SUVmax, SUVratio의 4가지 변수는 모두 유의한 차이가 있었다(p<0.05). 그리고, SUVratio가 가장 정확도가 높았다. SUVratio는 cut-off value 1.0에서 민감도 90.9%, 특이도 75.6%를 보였다. 1.5 cm 크기 이하의 작은 부신 종양에서는 양성과 악성 부신 종양을 감별하는데 SUVratio만 통계적으로 유의한 차이가 있었다(p<0.05). SUVratio는 cut-off value 1.0에서 민감도 80.0%, 특이도 86.4%를 보였다. 결론: 악성 종양 환자에서 우연히 발견된 부신 종양을 양성과 악성으로 감별 진단하는데 있어서 정량 분석을 통해 F-18 FDG PET/CT가 비조영증강(nonenhanced) CT에 비해서 더 정확한 정보를 제공할 수 있다고 생각된다. Purpose: We have evaluated characteristics of adrenal masses incidentally observed in nonenhanced F-18 FDG PET/CT of the oncologic patients and the diagnostic ability of F-18 FDG PET/CT to differentiate malignant from benign adrenal masses. Materials and Methods: Between Mar 2005 and Aug 2008, 75 oncologic patients (46 men, 29 women; mean age, 60.8±10.2 years; range, 35-87 years) with 89 adrenal masses incidentally found in PET/CT were enrolled in this study. For quantitative analysis, size (cm), Hounsfield unit (HU), maximum standardized uptake value (SUVmax), SUVratio of all 89 adrenal masses were measured. SUVmax of the adrenal mass divided by SUVliver, which is SUVmax of the segment 8, was defined as SUVratio. The final diagnosis of adrenal masses was based on pathologic confirmation, radiologic evaluation (HU<0:benign), and clinical decision. Results: Size, HU, SUVmax, and SUVratio were all significantly different between benign and malignant adrenal masses.(P<0.05) And, SUVratio was the most accurate parameter. A cut-off value of 1.0 for SUVratio provided 90.9% sensitivity and 75.6% specificity. In small adrenal masses (1.5 cm or less), only SUVratio had statistically significant difference between benign and malignant adrenal masses. Similarly a cut-off value of 1.0 for SUVratio provided 80.0% sensitivity and 86.4% specificity. Conclusion: F-18 FDG PET/CT can offer more accurate information with quantitative analysis in differentiating malignant from benign adrenal masses incidentally observed in oncologic patients, compared to nonenhanced CT.(Nucl Med Mol Imaging 2009;43(5):421-428)

      • KCI등재후보

        충청지역 ‘정신건강 전문가 학교방문지원사업’에 참여한 초등학생 중 학교폭력 경험군의 임상적 특성

        유세영 ( Se Young Yoo ),강윤형 ( Yun Hyoung Kang ),홍현주 ( Hyun Ju Hong ),이종국 ( Jonggook Lee ),손정우 ( Jung-woo Son ),이제정 ( Je Jung Lee ) 한국정신병리진단분류학회 2020 精神病理學 Vol.24 No.2

        Objectives: This study examined the characteristics of elementary school students who were referred to the Professional school visits outreach project in 2017 and 2018 and analyzed the emotional and behavioral characteristics of the students who experienced school violence. Methods: 160 elementary students were included in the analysis and the participant’s parents were asked to complete the Child Behavior Checklist 6-18. To obtain general information and experience of bullying, a semi-structured interview with the student, parents and the teacher was conducted. Results: The participants had a high proportion of vulnerable groups, and the main presumptive diagnoses were ADHD and depression, which were similar to those of the clinical group. Experiences of child abuse increased the risk of experiencing bullying (OR=2.16, p,0.5). The median scores of rule-breaking (p=.03) and aggressive behaviors (p=.01), externalization (p=.01) and conduct problems (p<.01) were significantly different among bullying participant roles. Bullies exhibited the most serious emotional behavior problems. Conclusion: The group with experience of school violence had more social immaturity and behavior problems, and less social and adaptability than the group without experience. Bullies had severe rule-breaking, aggression, externalization, and behavior problems, and showed the most problems in emotional behavior, and victims showed a tendency to have poor social and adaptation skills.

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