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송효경,신유주 가톨릭대학교 자연과학연구소 2003 자연과학논문집 Vol.24 No.-
새로운 비양론적 페로브스카이트(perovskite) 전이금속 산화물 Li_(0.33)Sr_(0.34+x)Sc_(x)Nb_(1-x)O₃, Li_(0.33)Sr_(0.34+x-y)Sc_(x)La_(y)Ta_(1-x)O₃을 고체 합성법으로 고온합성 하였다. 이들은 모두 정방형 구조를 갖고 있으며, 조성에 따라 단위세포와 A-자리 공극의 농도 및 공유결합성의 변화를 보여준다. 이들의 이온전도도는 300-770K 영역에서 AC-impedence 측정법으로 측정되었다. 이들이 상온 전도도는 10^(-5)Scm^(-1)정도를 나타내었고, 온도가 증가하면서 10^(-2)Scm^(-1)정도까지 증가하였다. 이러한 전도도의 변화는 화학결합 특성, 공극율 및 단위세포의 크기와 연관지어 이해할 수 있었다. New non-stoichiomtric perovskite oxides Li_(0.33)Sr_(0.34+x)Sc_(x)Nb(1-x)O₃ and Li_(0.33)Sr_(0.34+x-y)Sc_(x)La_(y)-Ta(1-x)O₃ were directly prepared by solid-state thermal reaction. As prepared samples show the simple cubic structure and a small variation of lattice parameter, the vacancy concentraticn and bond character with the composition. The ionic conductivity were determined around 10^(-5) Scm^(-1) near room temperature but increased up to 10^(-2) Scm^(-1) with temperature. The conductivity behavior has been discussed in relation with the variation of chemical bonding, the vacancy concentration and the effective volume of unit-cell of the lattice.
백병준,유명상,신재민,김효진,박훈,김장묵,오천환 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2
Background and Objectives : Paranasal sinus cancer is rare when compared with cancers of other sites. Because paranasal sinus is anatomically located adjacent to the orbit and skull base, it is difficult to remove the tumor completely with tumor free margin in advanced paranasal sinus cancer. This report was conducted to investigate clinical characteristics, histologic type and treatment outcome of paranasal sinus cancer. Material and Methods : Twenty-six cases with paranasal sinus cancer diagnosed at the Department of otolaryngology-Head and Neck Surgery, Soonchunhyang Cheonan Hospital from January 1991 to September 2000 were studied by chart review, telephone interview and letters retrospectively. Results : The male to female ratio was 4.2 : 1. Most patients were 6th and 7th decade. The maxillary sinus was the most commonly affected site(61.5%), followed by the ethmoid sinus(34.6%). The most common histologic type of malignancy was squamous cell carcinoma(57.6%), followed by adenocarcinoma(19.2%). Most patients presented with T_(3)/T_(4) or locally advanced disease, N_(0)(91.3%), and M_(0)(100%) Sixtynine pertcent of this study group underwent sugery as part of a mutimodality curative treatment plan or alone as curative treatment. Eighteen patients(69.2%) developed recurrent disease at a median time of 278 days after initial treatment. Kaplan-Meier analysis revealed the 5-year disease specific survival was 34.6%. Conclusion : Most patients with paranasal sinus cancer presented with locally advanced disease. Adanced T stage was highly predictive of poor prognosis. Recurrence rate was high and mostly occured within the second year after treatment.
감초 및 동충하초의 단순포진바이러스 (HSV)에 대한 항바이러스 효과
Yu Su Shin,Chan Hum Park,Ji Hye Yoon,Sang won Lee,Hyo Sun Cho,Hyo Jung Kang 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05
Background : Cordyceps militaris is a non-toxic, medicinal mushroom, which is known to possess anti-inflammatory and immunomodulating activities. And also, Glycyrrhiza uralensis is widely used as a crude drug in oriental medicine. However, the effects and mechanism of action of C. militaris and G. uralensis on Herpes simplex virsu (HSV), which is a serious skin disease. This study aimed to evaluate the effect of C. militaris and G. uralensis on Herpes simplex virus. Methods and Results : The results showed that the extracts and major compounds C. militaris and G. uralensis increased the TNF-α product on RAW 264.7. And also, these extracts and major compounds inhibited TNF-α product in RAW 264.7 induced by LPS. Querceitn, which was identified from G. uralensis, was showed Anti-virrus effect of Herpes simplex virus (HSV). Conclusion : Taken together, these results indicate that the anti-stomach cancer effect of C. militaris and G. uralensis in xenograft model implantated Epstein-Barr virus positive-stomach cancer cell line.
Two - Step Ammoniation of By - Product Fluosilicic Acid to Produce High Quality Amorphous Silica
Yu, Hyo Shin,Rhee, Kang In,Lee, Churl Kyoung,Yang, Dong Hyo 한국화학공학회 2000 Korean Journal of Chemical Engineering Vol.17 No.4
A two-step ammoniation was applied to neutralize the fluosilicic acid generated in the production of superphosphate fertilizer, and to recover high-quality amorphous silica in the second step. A fluosilicic acid solution at 12.6% or 25.3 wt% H₂SiF_6 was reacted with aqueous ammonia, precipitating silica and subsequently leaving NH₄F behind in the filtrate. Based on a fixed total of 7.2 moles of ammonia per mole of H₂SiF_6 (120% stoichiometry), ammonia at a molar ratio of ammonia to H₂SiF_6 of 2 to 6 was charged in the first step and the balance of 5.2-1.2 in the second step in four combination sets of ammonia addition. At a combination of 3 and 4.2 molar ratios in the respective first and second steps, amorphous silica of 99.7% purity was readily produced in the second step while a majority of the impurities were precipitated in the first step. The two-step ammoniation was near completion despite a non-equilibrium reaction. However, rapid ammoniation favored the crystallization of ammonium fluosilicate. A sharp pH change occurred between 1.5 and 2.5 NH₃/H₂SiF_6 molar ratios, indicating the rapid disappearance of SiF^(2-)_6 ion from the solution.
Studies on Mosquito Control Effectiveness of Bacillus thuringiensis var. israelensis Formulations
Shin, Yoo-Hang,Yu, Hyo-Sok,Kim, Heung-Chul 慶熙大學校 1985 論文集 Vol.14 No.-
1984年 1月 부터 1985年 4月까지 微生物 毒性製劑 Bacillus thuringiensis var. israelensis를 利用한 모기 幼蟲 感受性 및 驅除效果에 關한 屋內 및 小規模 野外實驗을 實施하였다. 1. 屋內 感受性實驗은 WHO International Center로부터 供給받은 B.T.I. 15種의 藥劑를 對象으로 빨간집모기 Culex pipiens 幼蟲은 LD_50致死率에서 토고숲모기 Aedes togoi 幼蟲에 比해 높은 感受性을 나타내었다. LD_50와 LD_90를 比較해 보면 ; Culex pipiens는 0.012-0.015㎎/1 과 0.024-0.030 ㎎/1이었으며, Aedes togoi는 0.037-0.379㎎/1와 0.069-0.671㎎/1이었다. 2. 모기幼蟲 以外의 他 水棲動物인 2種의 모기天敵 捕食魚, 왜 몰개 Aphyocypris chinensis 및 송사리 Aplocheilus latipes와 2種의 天敵無脊椎動物, 밀잠자리 Orthetrum triangulare melania 및 물방개 Cybister sp. 에 對한 B.t.i.의 安全性實驗에서는 B.t.i.. 處理濃度 1, 5, 10 및 100㎎/1의 濃度에서 모두 어떠한 致死效果도 나타내지 않아 比較的 넓은 範圍의 安全性을 確認할 수 있었다. 3. 小規模 野外實驗에서는 B.t.i. ABG-6018 藥劑로 下水池에서 2.5㎏/㏊의 濃度로 處理한 24時間 後에 58.7%, 72時間後에 68.0%의 상당한 防除效果를 나타내었으며, B.t.i. R 153.78 藥劑로 1.0㎏/㏊의 濃度로 處理한 結果 24時間後에 99.5%의 滿足할 만한 防除效果를 나타내었다. 本 實驗結果를 綜合해 보면 모기幼蟲에 對한 數種의 微生物 毒性製劑의 優秀한 感受性 및 防除效果로 앞으로의 繼續的인 硏究開發이 切實히 要求되며, 숲모기類에서 보다 집모기類에서 그 活用 및 效果가 期待되는 바이다.