하인두 편평세포암에서 후인두림프절 전이의 양상과 의의

유명상,김지희,노종렬,최승호,김상윤,남순열 대한이비인후과학회 2008 대한이비인후과학회지 두경부외과학 Vol.51 No.5

Little information about the incidence of retropharyngeal adenopathy and its impact on prognosis has been published. The purpose of this study is to investigate the incidence and prognostic significance of metastatic retropharyngeal adenopathy in patients with squamous cell carcinoma of the hypopharynx. Subjects and Method:The pretreatment CT/MRI of 121 patients with squamous cell carcinoma of the hypopharynx were reviewed for the presence of metastatic retropharyngeal lymph nodes. All patients were treated between 1996 and 2005. The influence on recurrence (local and regional), distant metastasis, and survival was retrospectively analyzed. Mean follow-up was 28.3 months. Results:Retropharyngeal node involvement was present in 21 (17.4%) patients. The clinical T staging was the most significant factor relating to the incidence of retropharyngeal adenopathy in multivariate analysis (p=0.006). The rates of regional recurrence and distant metastasis were significantly higher in patients with retropharyngeal adenopathy. Disease specific survival rate was significantly lower in the retropharyngeal node positive group (p=0.013). Conclusion:Retropharyngeal node involvement has a negative impact on the prognosis of squamous cell carcinoma of the hypopharynx. Patients are particularly at risk for distant metastasis, resulting in worse disease-specific survival. Retropharyngeal node involvement should be taken into account in designing the treatment plan for these patients. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:453-8)

1P-275 One-step synthesis of VO2 using hydrothermal

유명상,임상혁 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

VO2 (M/R) is traditionally binary compound with different polymorphs. Among them, VO2 (M/R) shows IR reflectance change at about 680C, so it is expected to be able to apply for the smart window. Various technologies have been developed to synthesize VO2(M), however most of them are complicated and need high cost. So they are not suitable for industrial applications. Hydrothermal method has the possibility for application because the route is simple and requires low temperature respectively although heat-treatment process is necessary to make pure phase. To solve this limit, we use VO2 seed which can accelerates the reaction, so it requires less temperature and can remove heat-treatment process. Finally, we synthesize pure Mo-doped VO2 (M) at lower temperature than other research and it is useful to realize for the smart window application.

아카이브 패러다임 변화에 따른 스토리텔링을 활용한 아카이브 대중화 연구

유명상 건국대학교 GLOCAL(글로컬)캠퍼스 스토리앤이미지텔링연구소 2023 스토리&이미지텔링 Vol.25 No.-

This study is a research on the popularization of archives using storytelling according to shifting archival paradigms. For conversion to popular archives in tune with shifting archival paradigms, this study examined the root cause why archives remain unpopular from the past to the present from a historical perspective, and investigated domestic and foreign cases of the operation of archives. Based on the concept of storytelling and storydoing, this study derived space of recording with functions of traditional archives, archives exhibition space for using archives and participation space where education and activities are provided for the public. 본 논문은 아카이브 패러다임 변화에 따른 스토리텔링을 활용한 아카이브 대중화 연구이다. 아카이브 패러다임 변화에 맞춰 대중적인 아카이브로의 전환을 위해 과거부터 현재까지 아카이브가 대중적이지 못한 근본적인 원인을 역사적인 관점에서 살펴보고, 국내외 아카이브 운영사례를 조사하였다. 본 연구는 스토리텔링과 스토리두잉 개념을 바탕으로 전통적인 기록관의 기능을 갖춘 기록 공간, 기록 활용을 위한 아카이브 전시 공간, 대중을 위한 교육 및 활동이 이루어지는 참여 공간을 도출하였다.

굴뚝 배출가스에서의 먼지(PM) 측정방법 비교 연구

유명상,송지한,유정훈,임슬기,이도영,김종호 한국대기환경학회 2018 한국대기환경학회 학술대회논문집 Vol.2018 No.10

기니픽 알레르기 모델에서 Leukotriene 길항제의 효과

유명상,이재형,박진규,이종대,김동욱,이병돈,장혁순,조중생 대한이비인후과학회 2003 대한이비인후과학회지 두경부외과학 Vol.46 No.12

Background and Objectives:The leukotriene (LT) receptor antagonist is subject to an on-going study of alergic rhinitis, nasal polyposis and chronic paranasal sinusitis. This study was designed to evaluate the change of nasal patency and morphological changes by assesing the role of 4-oxo-8-benzopyren-hemihydrate (ONO-1078, BH), a cysLT1 receptor antagonist to treatment of allergic rhinitis. Materials and Method:Sixty-five guinea pigs (GPs) were divided into 3 groups:μg DNP-As containing 1 mL Al (OH)3 and booster injections were given intraperitonealy 2, 4 and 6 weeks after the initial imunization. Measurements of nasal volume were made by acoustic rhinometry. Also transmission electron microscopy was performed to investigate ultrastructural changes of the nasal mucosal membrane in the LTD4 administrated GPs and the BH treated GPs. Results:and 6 hours after instillation of LTD4 in nonsensitized guinea pigs (GPs). However, neither nonsensitized nor sensitized GPs with systemic administration of BH showed any changes in nasal patency. Many neutrophils and eosinophils were sen in periva-scular space after local administration of LTD4 in control GPs. However there are no eosinophil infiltration into the subepithelial space in BH treated GPs in both nonsensitized and sensitized group. Conclusion:The results suggest that BH might be a potent LT receptor antagonist in the alergic model of GPs, which reduces nasal blockage and block chemotaxis of eosinophils to the (Korean J Otolaryngol 2003 ;46 :1028-34)

Maxillomandibular Advancement and Upper Airway Stimulation: Extrapharyngeal Surgery for Obstructive Sleep Apnea

유명상,Badr Ibrahim,Robert Wayne Riley,Stanley Yung Chuan Liu 대한이비인후과학회 2020 Clinical and Experimental Otorhinolaryngology Vol.13 No.3

There are many ways to categorize surgery for obstructive sleep apnea (OSA), one of which is to distinguish between intrapharyngeal and extrapharyngeal procedures. While the general otolaryngologist treating OSA is familiar with intrapharyngeal procedures, such as uvulopalatopharyngoplasty and tongue base reduction, extrapharyngeal sleep operations such as maxillomandibular advancement (MMA) and upper airway stimulation (UAS) have evolved rapidly in the recent decade and deserve a dedicated review. MMA and UAS have both shown predictable high success rates with low morbidity. Each approach has unique strengths and limitations, and for the most complex of OSA patients, the two in combination complement each other. Extrapharyngeal airway operations are critical for achieving favorable outcomes for sleep surgeons.

비과 영역에서 머신러닝의 적용

유명상 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.8

The revolutionary development of artificial intelligence (AI) such as machine learning and deeplearning have been one of the most important technology in many parts of industry, and alsoenhance huge changes in health care. The big data obtained from electrical medical records anddigitalized images accelerated the application of AI technologies in medical fields. Machinelearning techniques can deal with the complexity of big data which is difficult to apply traditionalstatistics. Recently, the deep learning techniques including convolutional neural networkhave been considered as a promising machine learning technique in medical imaging applications. In the era of precision medicine, otolaryngologists need to understand the potentialities,pitfalls and limitations of AI technology, and try to find opportunities to collaborate with datascientists. This article briefly introduce the basic concepts of machine learning and its techniques,and reviewed the current works on machine learning applications in the field of otolaryngologyand rhinology.

1P-154 One-pot synthesis of VO₂ using V(IV) seeding

유명상,임상혁 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1

Vanadium oxide(VO₂) has many different crystalline phase. Among them, M-phase vanadium oxide only exhibits reversible conversion of metal-to-insulate at transitional temperature. M-phase is insulator below transition temperature and it can be changed to conductor like metal over transition temperature due to the phase transition from M to R phase. Generally, high temperature and pressure is required to form pure M-phase vanadium oxide. But it is expensive and hard, so that hydrothermal route can be adaptable to synthesize vanadium oxide via solution process. To synthesize pure M-phase VO₂, here we adjusted new hydrothermal method using VO₂ seeding.

들판방황

유명상 한국외국어대학 학도호국단 1982 외대 Vol.17 No.1

성대돌기 육아종의 수술적 치료

유명상,송형민,노종렬,최승호,김상윤,남순열,Yu, Myeong-Sang,Song, Hyung-Min,Roh, Jong-Lyel,Choi, Seung-Ho,Kim, Sang-Yoon,Nam, Soon-Yuhl 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.1

Background and Objectives: Vocal cord granuloma is a exophytic inflammatory mass and caused by gastroesophageal reflux, voice abuse, endotracheal intubation. There has been a controversy in the treatment of vocal cord granuloma. Our aim of study is to know the clinical characteristics and the results of surgical management for vocal cord granuloma. Materials and Methods: We have reviewed and analyzed medical records of 55 patients who were diagnosed and surgically treated as vocal cord granuloma in Asan medical center from 1997 to 2005 retrospectively. Results: 25 cases were intubation granuloma and 30 cases were contact granuloma. In intubation granuloma, the clinical manifestation was hoarseness(70%), foreign body sensation(44%), chronic cough(21%). In contact granuloma, the clinical manifestation was hoarseness(67%), foreign body sensation(60%), throat clearing(21%). The recurrence rate after surgery was 8% in intubation granuloma and 33% in contact granuloma. Mean recurrence time was 4.1months in intubation granuloma and 3.2months in contact granuloma. Conclusion: Although there is no significant difference, recurrence rate after surgery was high in contact granuloma compared to intubation granuloma(p=0.125). Although this study is retrospective, surgical management must be considered in resolving diagnostic doubt, treating airway obstruction, and failure in conservative treatments.