분자동역학법에 의한 기액계면 분자의 운동특성에 관한 고찰

김혜민,박권하,최현규,최순호,Kim Hye-Min,Park Kweon-Ha,Choi Hyun-Kue,Choi Soon-Ho 한국마린엔지니어링학회 2005 한국마린엔지니어링학회지 Vol.29 No.1

An experimental study of molecular motions on a liquid-vapor interface is limited due to micro-scale characteristics of a system with an angstrom or a nanometer size Therefore, in recent, many studies for micro-scale systems have been conducted by a computer simulation because it is free from experimental limitations. In this study, through the molecular dynamic (MD) method. molecular behavior was clarified on a liquid-vapor interface and a criterion to distinguish between liquid and vapor was suggested by a potential energy and the number of neighboring molecules. At an interface. the potential energy of a molecule was increased but the number of neighboring molecules was decreased when the molecule moved into a vapor region from a liquid region, and vice versa.

불안장애의 치료추구시간에 대한 공존 정신질환의 영향 : 사회불안장애와 공황장애 간 비교

김혜민,하주원,임세원,오강섭,Kim, Hye-Min,Ha, Juwon,Lim, Se-Won,Oh, Kang-Seob 대한불안의학회 2012 대한불안의학회지 Vol.8 No.2

Objective : Individuals with anxiety disorders experience a wide range of time to seeking treatment (TST) as well as various comorbid mental disorders. The present study examined the TST in social anxiety disorder (SAD) and panic disorder. This study aimed to find out the influence of comorbid mental disorder on TST of anxiety disorder through the comparison of SAD and panic disorder. Methods : This study included 311 SAD and 378 panic disorder patients at the initial visit of psychiatric clinic. Contribution of clinical (number of comorbidity, comorbid type and onset age) and demographic (current age) factors to TST were investigated by multivariate analysis. Results : The median length of TST was 14.03 years in SAD and 2.26 years in panic disorder. In social anxiety disorder, fewer comorbidity, younger onset age, and older age were factors associated with delayed TST. In panic disorder, only younger onset age was associated with delayed TST. In both disorders, comorbid depressive disorder was associated with shorter TST. Conclusion : Our data provided the differences in illness behavior needing help based on comorbid mental disorders between SAD and panic disorder. In addition to comorbid disorder, factors affecting TST of anxiety disorder requires future investigation.

Lignan contents in Acanthopanax senticosus by HPLC

김혜민,조선행,국순자,이상현,Kim, Hye-Min,Cho, Seon-Haeng,Kook, Soon-Ja,Lee, Sang-Hyun Institute of Agricultural Science 2011 Korean Journal of Agricultural Science Vol.38 No.3

A reverse-phase system of HPLC using a linear gradient of acetonitrile and deionized water was developed for the quantification lignans, eleutherosides B and E, in Acanthopanax senticosus. The HPLC system consisted of linear gradient of acetonitrile and deionized water, and UV/VIS detection was set at 210 nm. Both eleutherosides B and E contents in different parts of A. senticosus were determined. As a result, the contents of eleutherosides B and E were measured in the leaves (trace amounts and 0.029 mg/g, respectively), stems (0.107 and 1.015 mg/g, respectively), roots (0.026 and 0.390 mg/g, respectively), and fruits (0.022 and 0.043 mg/g, respectively). Moreover, eleutherosides B and E in the water extract were found 0.011 and 0.171 mg/g, respectively.

Aldose reductase inhibitory activity of the methanol extracts from Korean folk plants

김혜민,한샘,최경,구자정,박광우,조은주,이상현,Kim, Hye-Min,Han, Saem,Choi, Kyung,Ku, Ja-Jung,Park, Kwang-Woo,Cho, Eun-Ju,Lee, Sang-Hyun Institute of Agricultural Science 2012 Korean Journal of Agricultural Science Vol.39 No.2

To search for the aldose reductase (AR) inhibitors from Korean folk plants, the inhibition of rat lens AR in vitro using the methanol (MeOH) extracts from Korean folk plants was investigated. Among fifty four Korean folk plants tested, the MeOH extract of Cedrela sinensis showed highest inhibition of AR ($IC_{50}$ value, 2.52 ${\mu}g/ml$). The plant C. sinensis has a possibility of new natural resources for the development of AR inhibitor for the prevention of diabetic complications.

한국인 조기난소부전 여성의 배란양상

김혜민,김재령,최은주,박은주,홍서유,이진용,박원일,Kim, Hye-Min,Kim, Jae-Ryoung,Choi, Eun-Joo,Park, Eun-Joo,Hong, Seo-Yu,Lee, Jin-Yong,Park, Won-Il 대한생식의학회 2008 Clinical and Experimental Reproductive Medicine Vol.35 No.3

Objective: Significant portion of premature ovarian failure patients ovulate intermittently and even can achieve pregnancy. The clinical features and reproductive potentials of Korean women with premature ovarian failure have never been elucidated. The purpose of this study is to assess ovarian follicular growth and ovulatory potential. Methods: Complete medical records of fifteen women with idiopathic premature ovarian failure were reviewed retrospectively. Subjects with more than 6 ultrasonographic scans and 36 months of follow-up period were included. Once the ovarian follicle was found by ultrasonography, the follicular growth was serially monitored. The result of ovulation induction of 6 cycles in 4 patients were also evaluated. Rate of positive ovarian follicle by ultrasound, rate of natural follicular growth and response of ovulation induction were assessed. Results: Among the 15 patients, 6 women (40%) had ovarian follicle in random ultrasonography. But the chance of positive follicle per ultrasonography scan was 7% (8 out of 115 scans). One out of 6 women eventually ovulated during the follow-up scan. In remaining 5 subjects, size of follicles remained unchanged. None of 6 ovulation induction cycles resulted successful ovulation. Conclusion: Incidence of positive ovarian follicle in Korean premature ovarian failure patients is lower than that of Western counterpart. This result, however, could not be directly compared because of the differences of study design. The ovulation rate by medical ovulation induction in this group is 0%, which is worse than the reported success rate of Western studies. 목 적: 조기난소부전 환자의 10$\sim$20%에서 난소기능이 회복될 수 있다고 하며 간헐적으로 배란이 되고 심지어는 임신이 가능할 수 있다는 보고가 있다. 그러나 한국의 조기난소부전 여성의 임상적 특징과 배란가능성은 논의된 적이 없다. 이 연구의 목적은 한국인 조기난소부전 환자에서 자연 난포의 발생 빈도와 배란유도의 가능성을 평가하는 것이다. 연구방법: 특발성 조기난소부전으로 진단된 15명 여성의 전체 진료기록을 후향적으로 연구하였다. 환자별로 6번 이상의 초음파 검사를 시행하였고 36개월 이상의 기간 동안 추적관찰을 하였다. 또한 4명의 환자에서 6주기의 배란유도시도를 하였다. 조사항목은 초음파 검사에서 난포의 발견율, 자연 난포 성장률과 배란유도를 시행한 경우에 그 반응을 평가하여 결과를 분석하였다. 결 과: 15명 중 6명은 초음파상 난포가 발견되었나 (40%) 초음파 검사 당 난포 발견 빈도는 7%였다 (115회 중 8회). 6명 중 한 명은 초음파 추적관찰 상 배란이 확인되었고 나머지 5명은 크기에 변화가 없었다. 배란유도를 시도한 6명 중 성공적인 난포 성장이 관찰된 예는 없었다. 결 론: 한국인 조기난소부전 환자에서 난포의 발견율은 이전 서양 연구에 비하여 낮다고 생각되지만 관찰 방법에 차이가 있어 직접비교는 불가능하다. 배란유도의 성공율은 0%로서 이전 연구에서 발표된 수준보다 낮았다.

일반논문 : 일본 커뮤니티 비즈니스 조직의 제도화에 관한 연구: 니가타현 이와후네 지역 사례를 중심으로

김혜민 ( Hye Min Kim ) 한국지방행정연구원 2010 地方行政硏究 Vol.24 No.3

제천시 노인복지시설 요양보호사의 식생활관리 인식과 행동 조사

김혜민 ( Hye Min Kim ),심혜진 ( Hye Jin Sim ),민성희 ( Sung Hee Min ) 한국식품조리과학회 2021 한국식품조리과학회지 Vol.37 No.4

Purpose: This study was conducted to examine the perception and behavior of caregivers in elderly welfare centers. Methods: A total of 84 caregivers performing dietary service at elderly welfare facilities answered this survey. The questionnaire focused on the general characteristics, status of meal services, nutritional knowledge, recognition and behavior of the caregivers. Results: Approximately 63.1% of the subjects were aware of lack of dietary therapy informations for the elderly. Dietary education experiences among caregivers affected the caregiver’s recognitions and behaviors. Recognition scores for ‘awareness of diet for geriatric diseases’, ‘check nutrition label, ingredients and food additives when purchasing foods’, and ‘reheat leftover before eating’ were higher in the dietary education experienced group. Moreover, the education experienced group’s correct answer ratio for nutritional knowledge was higher than that of the unexperienced group. Behavior scores for ‘serve various foods’, ‘exercise elderly to improve appetite’, ‘serve water enough’, ‘serve three times meals and snack exactly’, ‘not to serve greasy foods’, ‘search diet references for elderly’, ‘apply nutrition and hygiene knowledge’, and ‘use sepatate knives and cutting board when cutting meats and vegetables’ were higher in the education experienced group. Conclusion: Education experience has a significant impact on the perception and behavior of caregivers. Therefore, it is necessary to educate caregivers at elderly welfare facilities about dietary expertise.

밀폐형 식물생산시스템에서 광질과 광주기에 따른 씀바귀의 생육

김혜민(Hye Min Kim),강정화(Jeong Hwa Kang),정병룡(Byoung Ryong Jeong),황승재(Seung Jae Hwang) 한국원예학회 2016 원예과학기술지 Vol.34 No.1

본 연구는 밀폐형 식물생산시스템 내에서 광질과 광주기에 따른 씀바귀(Ixeris dentata Nakai)의 생육 증진을 위한 적정 생육환경 조건을 구명하고자 수행되었다. 씀바귀 종자는 240구 플러그 트레이에 파종하였고, 밀폐형 식물생산시스템에서 LED(R:B:W = 8:1:1)하에서 24시간 광주기로 3일간 발아 하였다. 묘는 230μmolㆍm<SUP>-2</SUP>ㆍs<SUP>-1</SUP>의 광도의 3종류의 광질(R:B:W = 8:1:1, R:W = 3:7, R:B = 8:2)과 4종류의 광주기[24/0, 16/8, 8/16, 4/20 (명기/암기)]하에서 20cm×20cm의 재식밀도로 난괴법으로 배치 하였다. 씀바귀는 정식 후 온도 21 ± 2°C, 상대습도 70 ± 10% 조건에서 40일 동안 재배 되었다. 관수는 담액식 양액 재순환 방식을 이용하였다(pH 7.0, EC 2.0dSㆍm<SUP>-1</SUP>). 24/0(명기/암기)의 광주기 처리와 RW 광질 처리에서 지상부와 지하부의 생체중과 건물중, 엽장, 엽면적은 가장 우수했다. 16/8(명기/암기)의 광주기 처리와 RB 광질에서 엽수는 가장 많았으며, 잎끝마름 발생률은 24/0(명기/암기)의 광주기 처리에서 다른 처리보다 높게 나타났다. 엽록소 값은 16/8(명기/암기) 광주기 처리에서 가장 높았으며 광질에 따른 차이는 없었다. 엽록소형광은 24/0(명기/암기) 광주기 처리에서 다른 처리구에 비해 현저히 낮은 값을 보였다. 결과적으로, 밀폐형 식물공장 시스템 안에서 씀바귀 재배의 경제적인 실현가능성과 생산적인 측면에서 16/8(명기/암기) 광주기 처리, RW의 광질에서 씀바귀를 재배하는 것이 가장 효과적인 것으로 판단된다. This study was conducted to examine the optimal environmental condition for promoting the growth of sowthistle as affected by light quality and photoperiod in a closed-type plant production system. Seeds were sown in 240-cell plug trays and then germinated for 3 days at a 24-hour photoperiod in a closed-type plant production system with LED lights (R:B:W = 8:1:1). Seedlings were transplanted and grown under 3 types of LED (R:B:W = 8:1:1, R:W = 3:7, or R:B = 8:2) and 4 photoperiods (24/0, 16/8, 8/16, or 4/20 hours) with 230 μmolㆍm<SUP>-2</SUP>ㆍs<SUP>-1</SUP> light intensity at a density of 20 cm × 20 cm. The experimental design was a randomized complete block design. Plants were cultured for 40 days un der the condition of 21 ± 2℃ and 70 ± 10% relative humidity after transplanting. Plants were fed with a recycling nutrient solution (pH 7.0 and EC 2.0 dSㆍ m<SUP>-1</SUP>) contained in a deep floating tank. Fresh weight and dry weight of shoot or root, leaf length, and leaf area were the greatest in the photoperiod of 24/0 (light/dark) with RW LED. The highest number of leaves occurred in the photoperiod of 16/8 (light/dark) with RB LED, while the incidence of tip burn was higher in the photoperiod of 24/0 (light/dark) compared to the other treatments. Chlorophyll value was the highest in the 16/8 (light/dark) photoperiod and there was no significant difference by light quality. Chlorophyll fluorescence was the lowest in the photoperiod of 24/0 (light/dark) compared with other treatments. Therefore, in terms of economic feasibility and productivity for Ixeris dentata Nakai cultivation in a closed-type plant production system, the results obtained suggest that plants grew the best when kept in a photoperiod of 16/8 (light/dark) and light quality of combined LED RW (3:7).

하악 편악 수술 교정 치료: 술후 하악골의 전상방 회전 재발을 고려한 3차원 수술 시뮬레이션의 활용

김혜민(Hye-Min Kim),임성훈(Sung-Hoon Lim),오지수(Ji-Su Oh),정서린(Seo-Rin Jeong),강신구(Shin-Gu Kang) 대한치과교정학회 2022 대한치과교정학회 임상저널 Vol.12 No.1

Isolated mandibular setback along the occlusal plane inevitably causes the development of the vertical bony step (VBS) between the mesial and distal segments of the mandible due to the angular difference between the occlusal plane and mandibular plane. Because the development of VBS causes postsurgical counterclockwise rotation of the mandible, simulation of this counterclockwise rotation should be incorporated into the simulation of surgery and the determination of surgical occlusion. In this case report, a 27-year-old female was treated to correct mandibular prognathism with asymmetry. During presurgical orthodontic treatment, maxillary molars were intruded to reduce the development of VBS during the isolated mandibular setback surgery. Despite this presurgical molar intrusion, 5.6 mm VBS was still developed at the 3D surgical simulation of single jaw surgery. Ideal jaw position was simulated, reducing this VBS to 2.1 mm, resulting in vertical overlaps of molars. To resolve these vertical overlaps or premature contacts, the distal segment was rotated 3.2° clockwise along the hinge axis. This simulation resulted in a surgical occlusion similar to a Class II open bite. During postsurgical orthodontic treatment, the mandible rotated 5.8° counterclockwise with the center of rotation 13 mm inferior to the hinge axis, resolving the VBS almost completely. This was slightly more than the anticipated amount of postsurgical rotation of the mandible. This case report showed that the isolated mandibular setback surgery can be done more predictably by incorporating the postsurgical counterclockwise rotation of the mandible into the simulation of surgery.

열린 대학 발달장애인에게 고등교육으로써 특수체육의 가치 탐색: 사례연구

김혜민 ( Hye-min Kim ),김재화 ( Jae-hwa Kim ) 한국특수체육학회 2021 한국특수체육학회지 Vol.29 No.2

본 연구의 목적은 발달장애 대학생을 대상으로 고등교육으로써 특수체육 가치를 탐색하는 것으로 프로그램에 참여한 인원은 발달장애 대학생 20명, 지도자 3명, 사회 복지사 2명이었으며, 그 가운데 대학생 6명, 지도자 2명, 사회복지사 2명이 인터뷰에 응하였다. 특수체육프로그램은 파라태권도를 적용하여 총 16주간 주1회(120분)로 진행하였으며. 자료수집은 심층면담, 관찰, 비개입자료로 시행되었다. 자료 분석은 관찰과 면담을 통해 수집된 자료를 분석하여 주제별 약호화(coding)와 분류(classification) 과정을 거쳐 1차 분석하였고, 다음 단계는 자료를 다시 한 번 확인하면서 각각의 내용을 대주제와 소주제에 맞게 정해진 번호를 부여하였다. 이러한 과정은 연구자간 논의를 통해 몇 차레 반복하여 주제 목록을 작성하였다. 그 결과 다음과 같은 결론을 도출하였다. 첫째, 고등교육을 위한 전문특수체육지도자의 필요성, 둘째, 발달장애인에게 고등교육으로서 특수체육의 의미, 셋째, 고등교육에서 특수체육수업 운영의 애로점, 넷째, 특수체육수업 참여를 통한 변화, 이러한 결론에 따라 후속연구에서는 발달장애인을 위한 대학차원에서의 특수체육수업 활성화 및 적용 방안을 선진국의 사례와 함께 모색하는 연구가 필요하다. 또한 발달장애인의 특성을 고려하여 장기간 공급할 수 있는 체계적인 프로그램 개발과 보급이 이루어져 그 효과성을 검정해 나가는 과정이 필요하다고 여겨진다. The purpose of this study is to explore the value of special physical education as higher education for college students with developmental disabilities. The number of participants in the program was 20 college students with developmental disabilities, 3 leaders, and 2 social workers, among which 6 college students and 2 leaders. 1 person and 2 social workers participated in the interview. The special sports program was conducted once a week (120 minutes) for a total of 16 weeks by applying Para Taekwondo. Data collection was conducted through in-depth interview, observation, and non-intervention data. For data analysis, the data collected through observation and interview was analyzed, and the subject-specific coding and classification processes were performed for the primary analysis. The next step was to review the data once again and analyze each content into a major topic and a sub-topic. A number was assigned accordingly. This process was repeated several times through inter-researcher discussions to create a list of topics. As a result, the following conclusions were drawn. First, the necessity of a professional special physical education instructor for higher education, second, the meaning of special physical education as higher education for people with developmental disabilities, third, difficulties in operating special physical education classes in higher education, fourth, changes through participation in special physical education classes, these conclusions Accordingly, in the follow-up study, it is necessary to study the revitalization and application of special physical education classes at the university level for the developmentally disabled along with cases from developed countries. In addition, it is considered necessary to develop and disseminate systematic programs that can be supplied for a long period of time in consideration of the characteristics of persons with developmental disabilities and to test their effectiveness.