구개열 아동 언어의 진단 평가

신효근,고승오,홍기환,서정환,고도흥,김현기 大韓顎顔面成形再建外科學會 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.1

유치레진치의 전치부 색조연구

현홍근 大韓小兒齒科學會 2007 大韓小兒齒科學會誌 Vol.34 No.4

유전치의 조기상실시 가철성 또는 고정성 공간유지장치의 제작이 필요하며, 보다 심미적인 결과를 얻기 위해서는 자연치아의 색조에 부합하는 레진치의 사용이 요구된다. 현재 가장 많이 사용되는 유치레진치는 Resin Natural Teeth™ (Nissin dental, Japan)로, A형 1번 색조와 A형 2번 색조로 구성되어 있다. 본 연구는 유치레진치의 전치부 색조특성을 이해하고 자연치아와의 색조비교를 위한 기본 자료를 만들기 위한 목적으로, Al 색조군과 A2 색조군의 유치레진치의 상악 4전치부의 순면을 각각 17 set에 대해 치아분광측색장치(spectrophotometer)인 ShadeEye NCC™(Shofu, Japan)로 각 3회씩 측정하여 CIE 표색계의 L^(*), a^(*), b^(*)값을 구하고 Kruskall-Wallis Test, Mann-Whitney U Test를 이용해 95%의 신뢰도(P<0.05)로 분석하여 다음과 같은 결과를 얻었다. 1. ΔE값 및 L^(*)값, b^(*)값의 분포로 볼 때, Al 색조군이 A2 색조군보다 치아위치별 색조차이가 작았다. 각 색조군내에서 a^(*)값의 치아위치별 색조차이는 거의 없었다(P>0.05). 2. Al 및 A2 색조군내에서의 ΔE값이 매우 작아(최대 ΔE≤1.23) 육안으로 그 차이를 구분하기 어려운 것으로 보이며, Al과 A2 색조군의 대표값 간의 ΔE값은 3.97로 육안으로 군 간의 차이를 구분할 수 있었다. 3. A1 색조군의 측정평균값은 L^(*)=73.8, a^(*)=-1.8. b^(*)=-4.7이었으며, A2 색조군의 측정평균값은 L^(*)=75.8,a^(*)= -2.7, b^(*)=-1.4이었다. 향후 자연 유전치에 대한 색조특성을 연구하여 본 결과와의 차이점을 비교해 색조적합성이 좋은 레진치의 개발이 필요할 것으로 사료된다. Removable or fixed space maintainer could be needed if one or some anterior primary teeth were missing, where resin pontics well-matched to natural primary teeth should be demanded to get an esthetic satisfaction. Resin Natural Teeth™(Nissin dental. Japan) is available currently in Korea, which consists of two shades ofcolors: type Al and A2. The purpose of this study is to elucidate the colors of the anterior primary resin teeth and to establish the data to compare those with the natural anterior primary teeth. CIE L^(*)a^(*)b^(*)s were measured each three times labially from 17 sets of maxillary four anterior teeth for type Al and A2 Resin Natural Teeth™ using ShadeEye NCC™(Shofu, Japan) which is one of spectrophotometers. The data were analysed statistically using Kruskall-Wallis Test and Mann-Whitney U Test. The results were as follows : 1. There were smaller teeth color differences in group Al than in group A2 when it comes to distributions of ΔE, L^(*)and b^(*). There were no statistically significant differences of a^(*) between teeth in the same group(P>0.05). 2. ΔE in group Al and A2 (maximum ΔE≤1.23) were very small, which could not be discerned by eyesight. ΔE between mean CIE L^(*)a^(*)b^(*)s of group Al and A2 was 3.97, which could be discernible by eyesight. 3. Mean measurements of group Al were L^(*)=73.8, a^(*)=-1.8, b^(*)=-4.7, and those of group A2 were L^(*)=75.8, a^(*)=-2.7, b^(*)=-1.4. It would be recommended that resin teeth compatible to the colors of the natural primary ones needed to be developed by investigating in vivo study.

법랑질 표면처리방법에 따른 치면열구전색재의 미세누출에 관한 비교연구

현홍근,김정욱,이상훈 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.3

최근 air-abrasion기술이 새로운 법랑질 표면처리법으로 소개되고 있는데, 이것이 산부식 처리한 것보다 치면열구전색 전처리에 있어 더 나은 결과를 보이는지 연구할 목적으로.저자들은 표면처리법 및 재료에 따른 미세누출도의 차이를 비교해 보고자 하였다. 9개의 군으로 나눈 시편치아에 산부식(1, 4, 7군). air-abrasion(2. 5, 8군). ail·-abrasion후 산부식(3. 6. 9군) 처리한 후, 3종의 치면열구전색재(1∼3군 : Teethmate-F.4∼6군 Ultraseal XT plus, 7∼9군 : DenSeal)로 전색, 중합하여 색소침투도를 관찰하였으며, 각 시편의 전색재를 분리, 주사전자현미경으로 관찰하여 다음과 같은 결과를 얻었다. 1 표면처리법에 따른 미세누출도는 air-abrasion군, 산부식군 air-abrasion 후 산부식군 순으로 작아졌다(p<0.05) . 단. 7군과 9군간의 유의차는 없었다. 2.미세누출도는 산부식군에서 7군, 4군, 1군, air-abl·asion군에서 8군, 5군, 2군, air-abrasion후 산부식군에서 9군, 3군. 6군 순으로 작아졌으나. 각각 4군과 7군 2군과 5군 3군과 6군간의 유의차는 없었다. 3. SEM상에서, 산부식군은 비교적 긴 레진돌기가 규칙적으로, air-abrasion군은 �裏�레진돌기가 불규칙적으로, air-abrasion후 산부식군에서는 이들이 혼재되어 있는 모습으로 관찰되었다. Recently, the reintroduction of air-abrasion technology in dentistry has added a new potential method of pre-treating teeth prior to placing sealants. The purpose of this in vitro study was to investigate microleakages of several pit and fissure sealants following various surface pre-treatment methods to the enamel , because there was a question concerning the validity of claim that this method was better than the conventional acid etching. Permanent molars were divided randomly into nine groups and treated accordingly: acid etching(group 1, 4, 7), airabrasion(group 2, 5. 8), acid etching after airabrasion(group 3, 6, 9). Then the authors placed and cured the three kinds of sealants(group 1∼3 : Teethmate-F, group 4∼6: Ultraseal XT plus, group 7~9: Denseal) according to the manufacturer's order. They were observed to determine the degree of microleakage . And these specimens were separated from the corresponding enamels and examined by Scanning Electron Microscope. The following results were obtained : 1. In comparing microleakage among tooth surface treatment methods. air-abrasion group (group 2, 5, 8) showed the greatest microleakage. while combination(air-abrasion + acid etching) group showed the least (p<0.05) . However, no significant differences were found between group 7 and 9. 2. The mean microleakages were ranked as follows(p<0.05) : In acid etching groups. group 7> group 4> group 1. In air-abrasive groups. group 8 > group 5 > group 2. In combination groups, group 9 > group 3 > group 6. However. no significant differences were found between group 4 and 7. between group 2 and 5, and be-tween group 3 and 6. 3. SEM showed that comparably longer resin tags were distributed regularly in acid etching groups and that shorter ones irregularly in airabrasion groups. It also showed that these two kinds of tags were distributed simultaneously in combination groups.

한국 어린이에서 하악 유절치와 그 계승 영구치의 선천적 결손 간의 관계

김현진,현홍근,김정욱,이상훈,김종철,한세현,장기택 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.1

많은 연구에서, 유치와 그 계승 영구치의 선천적 결손 간에는 상당한 연관관계가 있는 것을 보고하였다. 그러나 하악 전치부에서, 유치의 선천적 결손에도 불구하고, 그 계승 영구치는 정상적으로 존재하는 증례가 임상적으로 종종 관찰되기도 한다. 본 연구의 목적은 한국 어린이에서 하악 유절치와 그 계승 영구치의 선천적 결손 간의 상호 연관관계를 평가하는 데에 있다. 2005년 1월 1일부터 2008년 9월 5일까지 서울대학교치과병원에 내원하여 파노라마 방사선사진을 촬영한 6세 이하의 남녀 어린이 총 14,307명을 대상으로 하악 전치부의 치아양상을 관찰하여 유치와 영구치의 선천적 결손 관계를 평가하여 다음과 같은 결과를 얻었다. 1. 하악 유절치의 결손률은 0.24%였으며, 하악 유절치가 존재 시 후속 영구치가 존재할 승산(odds)은 7163.5였으며, 유절치의 결손 시 후속 영구절치가 존재할 승산(odds) 0.79였다. 2. 하악 유절치 결손의 증례 중 후속 영구치가 모두 존재하는 경우는 44.12%였다. 유절치의 양측 결손 시 후속 영구치가 하나라도 존재할 승산(odds)은 유절치 편측 결손 시에 비하여 1.57 배였다. 3. 유절치 결손이 있을 때 유절치의 편측 결손일 승산(odds)은 여자가 남자에 비해 2.2 배였다. 또한, 유절치 결손이 있을 때 후속 영구절치가 존재할 승산(odds)은 남자가 여자의 경우에 비하여 2.22 배였다. Many studies have shown that there is a strong relationship between the congenitally missing primary teeth and their succedaneous permanent teeth. However, especially in case of lower anterior region, we can observe the existence of permanent teeth even though their precedent primary teeth were missed at times. The purpose of this study was to reveal the relationship between the congenitally missing primary lower anterior teeth and their succedaneous permanent teeth in Korean children. Total of 14,307 children, under 6 years of age, who attended the department of pediatric dentistry, Seoul National University Dental Hospital, Seoul, Korea from January 1st 2005 to September 5th 2008 were radiologically examined using the panoramic x-ray in order to analyze the relationship between the congenitally missing primary lower anterior teeth and their succedaneous permanent teeth. The results were as follows : 1. The prevalence of congenitally missing lower anterior teeth in primary dentition was 0.24%. The odds ratio of both the primary and permanent anterior teeth being present was 7163.5 and only the permanent anterior teeth being present was 0.79. 2. The percentage of all succedaneous permanent teeth being present was 44.12% in cases of missing lower primary anteriors. The odds ratio of at least one succedaneous permanent teeth being present in cases of bilateral primary anterior teeth missing was 1.57 times more common than in cases of unilateral primary teeth missing. 3. The odds ratio of primary missing teeth being unilateral was 2.2 times higher in females. Moreover, the odds ratio of succedaneous permanent teeth being present in cases of primary teeth missing was 2.22 times higher in males.

심실 중격 결손에 의한 감염성 심내막염 환자의 치과치료

양정현,현홍근,김영재,김정욱,장기택,이상훈,한세현,김종철 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

무정자증 환자에 있어서 고환내 Leydig 세포의 변화에 관한 초미세형태학적 연구

기근홍,문현준,최봉남 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

The Leydig cells are identified in a peritubular boundary area of the testicular interstitium. These cells are differentiated in situ from myoid cells within the boundary layer and invaded into the interstitial tissue at puberty. The materials for study consisits of twenty cases of azospermia with cryptorchidism confirmed by sperm analysis at Chosun University Hospital. All cases were performed by hematoxylineosin stain and PAS stain for detection of Leydig cells, and ultrastructural abservation for change of cytoplasmic organelles in azospermic patients. The results obtained are follows. The leydig cells in the interstitial tissue of azospermic testis forming large clusters and showing hypertrophic change. Within the cytoplasm, numerous dilated endoplasmic reticulum, disrrupted mitochondria and osmiophilic round bodies are seen. A few myoid cells within the boundary layer are hypertrophied and show an intermediate pattern between myoid cells and Leydig cells. There are unusual cells, either single or clusters, within the thickened boundary layer. They can be identified as Leydig cells similar to the ordinary Leydig cells in the interstitial tissue. This findings indicated that ordinary function of Leydig cells are intact, but it is thought that the decreased function may be due to damage of the testis in cryptorchidism.

비혈연간 동종골수이식에 의해 치료된 중증 재생불량성빈혈 1예

김현중,이홍기,이방훈,이창근,이종태,정현식,김원석,윤성수,강원기,박근칠,김대식,고영혜,박찬형 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1

비혈연간 동종골수이식은 혈연간 동종골수이식이 불가능한 환자에서 기존의 면역역제요법으로 효과가 없었던 경우나 재발한 경우에 적응증이 될수 있다. 이식 거부와 이식편대숙주병의 발생이 골수 이식의 성공률을 감소시키므로, 보다 강력한 conditioning regimen의 사용과 T cell이 제거된 골수를 사용하는 것이 필요하다. 기존의 high dose corticosteroid나 cyclosporine에 대하여 불응성인 이식편대숙주병의 치료를 위해서 ATG와 Mycophenolate mofetil (Cellcept®) 의 사용이나 Tacrolimus, Methotrexate와 같은 다른 면역억제제치료를 고려해 볼 수 있다. It is known that allogenic bone marrow transplantation is the most effective treatment for aplastic anemia. However, this treatment is only applicable to a minority of patients because the proportion of patients who have HLA-matched siblings about 25% to 30% of all the aplastic anemia patients. In the case of the absence of HLA-matched donor, unrelated allogenic bone marrow transplantation is considered. However, (because of severe acute and chronic GVHD and graft failure) the success rate of this approach is only 20~30%. Recently, it was reported that increased immunosuppressive condition combined with T cell depletion of the marrow graft would result in greater success. There was no case of successfully treated aplastic anemia patient by unrelated allogenic bone marrow transplantation in Korea. Here, we report a case of severe aplastic anemia successfully treated with unrelated allogenic bone marrow transplantation.

법랑아세포성 섬유치아종

장현선,기근홍,김수관 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

Ameloblastic fibro-odontoma consists of ameloblastic fibroma combined with an odontoma. Ameloblastic fibro-odontoma affects somewhat younger patients than ameloblastic fibroma and 62% of patients are younger than 10 years. Clinical, radiologic, and histologic studies were performed in 9-year-old child of ameloblastic fibro-odontoma. Location of the lesion was the upper molar area. Radiographically, the opaque odontomatous tissues was observed in a circumscribed, but otherwise radiolucent area. Histologically, typical ameloblastic fibro-odontoma was associated with the calcifying or calcified dental tissues of an odontoma. In this paper, a case of ameloblastic fibro-odontoma of the maxilla and a review of the literature is presented.

濟州島 方言의 活用語尾에 대한 硏究

姜根保,玄平孝,金洪植 제주대학교 1974 논문집 Vol.6 No.-

In this paper, the conjugational endings of the Cheju-Do Dialect have been examined through the actual utterances of native speakers. The conjugational endings have been classified into two categories-terminal endings and pre-terminal endings. An analytical processing has disclosed that pre-terminal endings are used to show the indicative, retrospective, and presumptive moods, while terminal endings to show the interrogative, imperative, and optative moods. the conjugations forms characteristic of the Cheju-Do Dialect and their special features are as follows: 1. Indicative mood. The basic form of the indicative mood is {-n??-} as seen in '-n??ni'and '-n??nya' however the Cheju-Do Dialect has '-na' to show the indicative mood and it is most peculiar to and characteristic of the dialect. This '-na'can be analyzed into {-n??-}, an indicaive morpheme, and {-a}, a conjugational ending of the declarative mood. The {-ne-}of '-bneda' is another morpheme for the indicative mood characteristic of the Cheju-Do Dialect and '-nye' is another indicative ending which is analyzed into {-ni-} and {-e} 2. Retrosectve mood. The basic ending form in the retrospective mood is {-d??-} as shown in '-d??ra' and '-d??nya'. The Cheju-Do Dialect, however, has many varients, among which {-d??-} and {-de} are ones found also in other regional dialects but peculiar to Cheju-Do are {-de-} of 'bdeda' '{-a/??-}' of '-ara/??r??', {-an/??n} of '-ange/??nge' 3. Presumptive mood. The basic form of the presumptive mood is {-k'-} in 'k'iy??' '-k'??ra' '-k'inya' '-k'uda' and peculiar to the dialect are '-k'iy??' '-k'??ra' '-k'uda' '-k'uga' '-ry??'. also '-k'a' '-lta' '-lti' serve as presumptive endings in the Cheju-Do Dealed. 4. Honorific System. There are two morphemes to be used in the honorific system of the Cheju-Do Dialecd. One is {-b-} which is traceable to 's??b' and the other {-u-}, the indigenous form to Cheju-Do. 5. Imperative mood. The imperative mood of the Cheju-Do Dialect is composed by connecting imperative terminal endings directly to the root forms. '-ra' and '-bs??' are some of these endings. 6. Optative mood. The optative mood is composed by connecting optative endings to the roof forms. These endings are seen in '-ja' and '-bjui'. Viewed from a diachronic standpoint, these conjugational endings range widely in their developments. The endings form of the 7th or 8th century are found in the contemporary dialect along with the ending forms of the 18th or 19th century. This kind of confusion and mixture is another feafure of the Cheju-Do Dialect.

八堂湖 水質에 對한 WQRRS模型의 適用性에 關한 硏究

李弘根,金炫龍 서울大學校 保健大學院 1994 보건학논집 Vol.31 No.1

This study was carried out evaluating WQRRS (Water Quality for River-Reservoir System)model applicability for water quality prediction of the Lake Paldang. Reaction coefficients of WQRRS model was calibrated by using observed data in 1989, and correspondence of fitness of predicted values from the calibrated WQRRSmodel to water quality data observed in 1990 was evaluated and verified by using the Reliability Index(RI). The major results of this study are as follows; 1) the revised reaction coefficients are 0.3 day­¹ for CarbonaceousBOD decay rate, 0.18 day­¹ for Ammonia decay rateand 0.21day­¹ for Nitrite decay rate, and such revisedvalues are more, higher than the default values, 2) the calibrated WQRRS model is adequate to predict the water quality of the Lake Paldang, as results of analysis of RI values and fitness of predicted values to observed values.