급성 뇌경색 환자에서 경색 위치가 심근 효소치 상승에 미치는 영향

윤경호,박현영,박성욱,장혁,김요식,조광호,유남진,김남호,오석규,정진원 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

신도시 개발에 따른 첨두유출량과 토양유실량 변화에 관한 연구 -목포시 남악 신도시 개발지를 대상으로-

우창호 ( Chang Ho Woo ),조남열 ( Nam Yui Cho ) 한국환경영향평가학회 2002 환경영향평가 Vol.11 No.4

The purpose of this study is to explore the hydrological impacts and soil loss variation due to the land use change of Namak New Town development area. The analysis of hydrological effects and soil loss variation has been carried out using GIS in this study. In order to estimate the peak runoff volumn, the Rational Method which is the most popular technique to predict runoff amounts is used. To estimate the soil loss in the study area, Universal Soil Loss Equation(USLE), which is one of the most comprehensive and useful technique to predict soil ersion is adopted. The result of this study has shown that the peak runoff volume and the total soil loss increse according to the land use change. The peak runoff volume and the total soil loss have been incresed about 2 time and about 48 times more than that of pre development. The increasing of the peak runoff volume can be effective erosion, flooding and so on. A careful city planning is the first essential step to minimize the environmental impacts and to construct the ecological city.

Hepatoprotective and Antioxidative Activities of <i>Cornus officinalis</i> against Acetaminophen-Induced Hepatotoxicity in Mice

Lee, Nam-Hun,Seo, Chang-Seob,Lee, Ho-young,Jung, Da-Young,Lee, Jun-Kyung,Lee, Jin-Ah,Song, Kye Yong,Shin, Hyeun-kyoo,Lee, Mee-Young,Seo, Young Bae,Kim, Hokyoung,Ha, Hyekyung Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-

<P>The fruit of <I>Cornus officinalis </I>Sieb. et Zucc. is commonly prescribed in Asian countries as a tonic formula. In this study, the hepatoprotective effect of ethanolic extracts of the fruit of <I>C. officinalis</I> (ECO) was investigated in a mouse model of acetaminophen- (APAP-) induced liver injury. Pretreatment of mice with ECO (100, 250, and 500 mg/kg for 7 days) significantly prevented the APAP (200 mg/kg) induced hepatic damage as indicated by the serum marker enzymes (AST, ALT, and LDH). Parallel to these changes, ECO treatment also prevented APAP-induced oxidative stress in the mice liver by inhibiting lipid peroxidation (MDA) and restoring the levels of antioxidant enzymes (SOD, CAT, and HO-1) and glutathione. Liver injury and collagen accumulation were assessed using histological studies by hematoxylin and eosin staining. Our results indicate that ECO can prevent hepatic injuries associated with APAP-induced hepatotoxicity by preventing or alleviating oxidative stress.</P>

Anti-Inflammatory Effect of By-Products from<i>Haliotis discus hannai</i>in RAW 264.7 Cells

Rho, Ho-Seok,Kim, Hyang,Kim, Jung-Ae,Karadeniz, Fatih,Ahn, Byul-Nim,Nam, Ki-Ho,Seo, Youngwan,Kong, Chang-Suk Hindawi Limited 2015 Journal of chemistry Vol.2015 No.-

<P>Several reports promoted the potential of shellfish due to their ability to act as antioxidant, anti-inflammatory, and antimicrobial agents. Pacific abalone,<I>Haliotis discus hannai</I>viscera is, reported to possess bioactivities such as antioxidative stress and anti-inflammatory. In this study, anti-inflammatory potential of mucus-secreting glands from shell-shucking waste of<I>H. discus hannai</I>was evaluated using RAW 264.7 mouse macrophage cell model. Results indicated that presence of<I>H. discus hannai</I>mucosubstance by-products (AM) significantly lowered the nitric oxide (NO) production along the expressional suppression of inflammatory mediators such as cytokines TNF-<I>α</I>, IL-1<I>β</I>, and IL-6 and enzymes iNOS and COX-2. Also, AM was shown to increase expression of anti-inflammatory response mediator HO-1. Presence of AM also scavenged the free radicals<I>in vitro</I>. In conclusion, by-products of<I>H. discus hannai</I>are suggested to possess notable anti-inflammatory potential which promotes the possibility of utilization as functional food ingredient.</P>

林土의 有機物의 分解速度와 無機養料의 垂直分布에 關한 考察

金遵敏,張楠基,鄭玩鎬 서울대학교 교육대학원 학술연구회 1966 論文集 - 서울대학교 교육대학원 Vol.3 No.-

Kim Choon Min, Chang Nam Kee and Chung Whan Ho: Decomposition rate of plant residue and the vertical distibution of mineral nutrients in the woodland soil. The relationship between decomposition rate of litter and the amount of mineral nutrients dispersed to the soil horizons were studied on the oak and pine forest stand. The results are as follows: 1. Decomposition rate of litter was highest in the F horizon of the oak stand, however in the pine stand it was highest in H horizon. 2. The correlation coefficients between decomposition rate and humus, organic carbon, moisture content, calcium, phosphorus, and nitrogen in the pine stand are; 0.90, 0.98, 0.76, 0.98, and 0.88, in oak stand; 0.97, 0.93, 0.92, 0.97, 0.74 and 0.73. 3. Factors which affect the decomposition rate of litter are humus, organic carbon, moisture content, calcium, phosphorus and nitrogen. 4. Among the variables, PH, moisture content and phosphorus under the oak and pine forest showed significant differences in each horizon. 5. C/N ratio of pine stands is higher than that of oak stands studied. 6. The vertical distribution of mineral nutrients is highly related with the amount of humus accumulated on top soil.

통합 차량 네트워크 시스템을 위한 노드 기반 FlexRay-CAN 게이트웨이 설계

김만호(Man Ho Kim),이석(Suk Lee),이경창(Kyung Chang Lee),하경남(Kyong Nam Ha) 한국자동차공학회 2011 한국자동차공학회 부문종합 학술대회 Vol.2011 No.5

As vehicles become more intelligent, in-vehicle networking (IVN) systems such as controller area network (CAN) or FlexRay are essential for the convenience and safety of drivers. To expand the applicability of IVN systems, attention is currently being focused on the communication between heterogeneous networks such as body networking systems or chassis networking systems. Message mapping based gateway was developed to communicate between FlexRay and CAN network to improve exchanging information of vehicle. However, there are obstacles for the wide acceptance of the FlexRay-CAN gateway of vehicle. First, when message ID was changed of network, gateway must be reloaded changed message mapping table. Second, if the exchanging message is increased in the network, software complexity of gateway is increased rapidly. In order to overcome these obstacles, this paper presents a node mapping -based FlexRay-CAN gateway for IVN systems. In addition, this paper presents a node mapping based FlexRay-CAN gateway operation algorithm along with the experimental evaluation for ID change.

적응적인 웹 사이트 설계를 위한 퍼지인식도 시뮬레이션에 관한 연구

이건창(Kun Chang Lee),정남호(Nam Ho Chung) 한국경영학회 2001 經營學硏究 Vol.30 No.2

As the main stream of electronic commerce changes from B2C to B2B, the importance of a strategic web site design is being recognized more than ever. In this sense, this study proposes a new approach to an adaptive design of the web site by using the stratified fuzzy cognitive map (FCM). Its main virtue lies in capability of changing specific components on the web site with its subsequent effects upon other components being objectively considered. By doing so, we can maintain total effectiveness of the website design. This advantage of the proposed approach can be compared with the traditional approach where the web site design has been changed without paying a due attention to the related components. We gathered 134 questionnaire responses. By analysing the questionnaire results, the causal weights of the FCM were computed objectively. Then the FCM was transformed into a stratified FCM by using Lee & Cho (1998)`s approach. On the basis of the stratified FCM and four scenarios, we performed web site design simulation. The simulation results showed that the proposed approach could be used effectively for analyzing the web site design in an adaptive manner when the market situation is changing.

회분식 발효에서의 전기투석에 의한 젖산의 동시분리

이은교,장용근,장호남,김인호 한국산업미생물학회 1995 한국미생물·생명공학회지 Vol.23 No.5

전기투석속도에 영향을 주는 인자로서 전압, 젖산농도, 온도, 젖산염 종류, pH등을 살펴보았다. 전압은 예상대로 전기투석속도에 가장 큰 영향을 주는 인자로 밝혀졌으며, 전압이 높아질수록 전기투석속도가 크게 증가하여 4,6,8 V의 전위차하에서 각각 0.29, 1.81, 4.43 g/h의 평균 전기투석속도를 얻었다. 동일 전압 하에서 source solution 농도가 높아질수록 전기투석속도는 증가하였다. 또한 전기투석실험 말기에 source solution으로부터 침투물 용액으로의 젖산 이동이 두 용액간의 농도차에 의해 제한받는 현상도 관찰되었는데, 이런 현상은 전류에 의한 젖산이온 이동과 농도차에 의한 back-diffusion이 상쇄되기 때문인 것으로 해석되었다. 25℃와 35℃에서의 전기투석실험과에 따르면 10℃ 온도 상승에 대해서 전기투석속도는 약 10% 증가를 보였다. pH를 4.0, 5.0, 6.0로 변화시켜 본 결과, pH 4.0에서의 전기투석속도가 가장 빠르게 나타났고, Na-lactate보다는 NH_4-lactate 형태가 전기투석속도면에서 유리함을 알 수 있었다. 회분식 발효시 전기투석에 의한 in situ 젖산 분리효과를 알아보기 위해 pH 조절만 한 경우, pH 조절없이 전기 투석만 한 경우, pH 조절과 전기투석을 동시에 한 경우 세가지 면에서 살펴보았다. 세가지 경우 중 pH 조절을 하면서 전기투석을 한 발효가 전반적으로 수율이나 생산성 면에서 효과적이었다. 초기 포도당 농도가 50g/l인 경우에는 현저한 차이를 보이지 않았으나, 150g/l인 경우에는 약 1.7배의 생산성 효과를 얻을 수 있었다. Effects of lactate concentration, temperature, counter ions, pH as well as voltage (current) in batch electrodialysis (ED) experiments with a 3-compartment unit were investigated. The applied voltage was found to be the most critical factor as expected. The electrodialysis rate increased with the lactate concentration of the source solution. The amount of lactate transferred was limited by the lactate concentration difference between cathode and permeate compartments. The electrodialysis rate did not heavily depend on temperature change. The electrodialysis rate of NH_4-lactate was faster than that of Na-lactate and both lactates showed the highest electrodialysis rate at a pH of 4.0. A little amount of non-ionic glucose diffused through the anionic membrane to the permeate compartment. To test the effectiveness of the in situ recovery of lactic acid from fermentation broth by ED, three cases of batch culture were carried out; pH control only, ED only, and pH control and ED. The case with both pH control and ED was more efficient than that with pH control only in the aspects of productivity and product yield.

석유 탈황용 미생물 분리 및 디젤유에 대한 탈황능 평가

조경숙,류희욱,장호남,장용근,장제환,손호용 이화여자대학교 환경문제연구소 1997 이화환경연구 Vol.1 No.-

석유 탈황을 위한 생물 촉매 개발 및 이를 사용하는 생물학적 공정에 관한 연구의 일환으로, DBT(Dibenzothiophene)를 모델 화합물로 선정하여, 국내 정유회사 주변의 윈유 누출 오염토양으로 부터 3개월간의 연속배양 및 집식배양을 통해 DBT를 효율적으로 탈황, 제거할 수 있는 60여종의 균주를 분리하였다. 선별된 균들 중 A23-3은 DBT를 유일황원으로 성장 가능하면서, 탄소원으로 hexadecane 은 이용하지 못하였으며, DBT의 포도당을 포함한 기본염 최소 배지에서 만족할 만한 속도로 DBT로 탈황하였다. 또, yeast extract나 trace metal solution을 첨가한 경우 DBT 제거속도는 약 4.5-6.5배 정도 증가하였다. 실제의 디젤유를 직접 처리한 경우, DBT 제거속도는 0.045g DBT/g-cell·hr이었다. 특히, 이 경우, DBT이외의 C₁₄ 이상의 heavy aromatic 화합물의 제거도 효율적으로 이루어짐을 알수 있었다. 따라서 A23-3 균주는 저유황, 저방향족 청정 디젤유 생산에 매우 유용하게 이용되리라 사료된다. For the development of biocatalysis and processes for microbial desulfurization of petroleum, more than 60 microbial strains capable DBT(Dibenzothiophene) degradation were isolated from oil-polluted soils through 3 months of continuous and enrichment cultures. Among them, A23-3 strain could grow on DBT as the only sulfur source, while hexadecane was not utilized as a carbon source. The rate of desulfurizaton b A23-3 in a DBT-glucose medium was satisfactory. The addition of yeast extract or trace metal solution accelerated the rate of desulfurization about 4.5-6.4 times. In case of actual diesel oil treatment, the specific rate of DBT degradation was 0.045g-DBT per g-cell·hour. A number of aromatic compounds heavier than C₁₄ in diesel oil were also degraded by A23-3 strain was evaluated as a good catalyst for the production of low-sulfur, low-aromatic clean diesel oil.

中風病辨證診斷標準에 의한 臨床的 硏究

任長信,文祥官,高昌男,權正男,曺基湖,金永錫,裵亨燮,李京燮 경희대학교 1997 慶熙醫學 Vol.13 No.3