The Missional Fourfold Gospel Ministry: Focused on its Theoretical Foundation and Practical Curriculum

Heun Ik Chang 서울신학대학교 글로벌사중복음연구소 2021 World Christianity and the Fourfold Gosepl Vol.6 No.1

水容性造影劑를 使用한 腰椎簡核脫出症의 脊髓腔撮影에 關한 硏究

金載敞,鄭萬翼,李方炘 최신의학사 1975 最新醫學 Vol.18 No.2

For last 5 years (1968-1973) lumbar myelography with water soluble contrast medium (Myelotrast or abrodil, sodium-monoiodomethyl sulphonyl ICH, SO, Na) has been performed in 324 patients who were impressed or diagnosed as lumbar disc herniation in Radiological Department of National Medical Center, Seoul, Korea. The results areas followings. 1) Age and sex distibutions were male 180, female 144 and from 12 to 68 year old. Highest incidence is noted in 30-39 age group (91 cases). 2) In simple film, spondylosis was noted in 96 cases(29.6%). scolisois in 79(24.4%), straightening in 62(19. 1%) and disc space narrowing in 154(48%). 3) The distribution of disc space narrowings (154) in simple film is highest in L,-Ls level (113) and 22 in Ls-S, level, 18 in L3-L, level etc. 4) In lumbar myelography, positive findings in 180 cases (55.5%), non-specific in 124 cases (33.3%) and borderline in 20 cases (6.2 %) . A) The contents of the positive fingings(180) are single disc herniation in 154 cases multiple disc herniation in 26 cases. b) The distribution of single disc herniation (154) are 122 cases in L,-Ls level, 23 cases in Ls-S, level etc. c) In multiple lesions(26), highest incidence in L,-L5-S, level 14 cases and 8 cases in L,-L,-L5 level etc. 5) Surgical operation was performed in 135 cases (41. 6% of all). 6) Comparing myelographic findings with operative findings, false negative(radiologically free but positive in surgery) in 6 cases (5% of operation case), false positive(radiologically positive but free in surgery) in 2 cases(1% of surgery case) and 94%(127) was detactable in myeloraphy preoperatively. 7) Advantages of the water soluble contrast medium in lumbar myelography.For last 5 years (1968-1973) lumbar myelography with water soluble contrast medium (Myelotrast or abrodil, sodium-monoiodomethyl sulphonyl ICH, SO, Na) has been performed in 324 patients who were impressed or diagnosed as lumbar disc herniation in Radiological Department of National Medical Center, Seoul, Korea. The results areas followings. 1) Age and sex distibutions were male 180, female 144 and from 12 to 68 year old. Highest incidence is noted in 30-39 age group (91 cases). 2) In simple film, spondylosis was noted in 96 cases(29.6%). scolisois in 79(24.4%), straightening in 62(19. 1%) and disc space narrowing in 154(48%). 3) The distribution of disc space narrowings (154) in simple film is highest in L,-Ls level (113) and 22 in Ls-S, level, 18 in L3-L, level etc. 4) In lumbar myelography, positive findings in 180 cases (55.5%), non-specific in 124 cases (33.3%) and borderline in 20 cases (6.2 %) . A) The contents of the positive fingings(180) are single disc herniation in 154 cases multiple disc herniation in 26 cases. b) The distribution of single disc herniation (154) are 122 cases in L,-Ls level, 23 cases in Ls-S, level etc. c) In multiple lesions(26), highest incidence in L,-L5-S, level 14 cases and 8 cases in L,-L,-L5 level etc. 5) Surgical operation was performed in 135 cases (41. 6% of all). 6) Comparing myelographic findings with operative findings, false negative(radiologically free but positive in surgery) in 6 cases (5% of operation case), false positive(radiologically positive but free in surgery) in 2 cases(1% of surgery case) and 94%(127) was detactable in myeloraphy preoperatively. 7) Advantages of the water soluble contrast medium in lumbar myelography. a) Completely and quickley resorbed and eXcreted from the body through the urine in d matter of minutes. b) Mixes completely and homogenusly with spinal fiuid. c) It can fill out every little corner of the spinal canal. d) Low incidence of pseudoindentation(1%). e) It is not so dense that fine spinal nerve to be visible through the contrast.

사람 간암의 염색체 이상

장성익(CHANG Sung Ik),백상헌(BAIK Sang Heun),김홍태(KIM Hong Tage) 대한체질인류학회 1995 해부·생물인류학 (Anat Biol Anthropol) Vol.8 No.2

간암에 있어서 HBV와 관련된 암화과정을 알기위하여 원 발성 간암과 간암 세포 주(Hep 3B PLC/PRF/5 Hep G2)를 대상으로 간암조직 및 간암 세포 주를 배양하여 G-band법으로 염색체를 조작하여 세포유전학적으로 분석한 결과를 요약하연 원 발성 간암에서는 염색체 이상은 발견되었지만 모두 10% 미만으로 clone화 되어 있지 않았다. 반면에 간암 세포 주에서는 염색체 이상이 모두 clone화 되어 있었는데 Hep 3B 에서는 1p21 부위의 결손과 6q14 부위의 결손과 t(1 11)(p11 q13)의 전좌 형이 특징 이었다。 이들 염색체 이상 부위에는 AMYIA CGA 및 SEA 와 HSTF1 유전자가 존재하였다. PLC/PRF/5 세포 주에서는 1p21 및 6q14의 결손은 Hep 3B와 같았으며 그 외 1q32 및 1p32의 결손이 clone화 되어 있었고 이부위에는 CRI과 MYCL1 유전자가 각각 존재하는 부위였다. Hep G2 세포 주에서는 1p31 및 1q22 부위의 결손이 특징이었고 GSTI과 DAF 유전자가 6q11 및 1p22의 결손 부위에는 CGA 및 SKI 유전자가 각각 존재하는 부위였다. 위의 결과로 미루어 보아 간암의 암화과정은 HBV가 AMYIA 유전자 부위나 근처에 삽입되어 이 유전자의 기능장애를 일으키고 다음 CGA 유전자가 세포조절능력을 상실시켜 암화과정을 짧기 시작하였고 SEA HSTF1이나 MYCL1 같은 암유전자는 더욱 악성 쪽으로 진행시킨 것으로 생각되며 Hep G2 같은 HBsAg(-) 암에서는 어떤 원인이 GSTI 과 DAF에 기능장애를 일으켜서 CGA에 의한 세포조절능력을 상실하여 암화과정을 짧기 시작하였고 SKI 암유전자가 악성 쪽으로 작용했을 것으로 추측된다. 어떤 원인이든 CGA 유전자의 기능장애와 관계있는 듯 하므로 향후 CGA 유전자와 간암과의 관계를 계속 연구하는 것이 필요할 것 같다.

성상신경절 차단요법에 의한 돌발성난청의 치료효과

장한익,조태환,전일훈,김정수,이상흔,성창섭 釜算慶南耳鼻咽喉科學會 1990 임상이비인후과 Vol.1 No.2

B형 간염 virus 양성 간암과 음성 간암의 세표유전학적 차이

김홍태,백상헌,장성익 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.4

To a better understanding for molecular mechanism of oncogenesis in hepatoma, primary hepatocellular carcinoma and hepatoma cell lines(Hep 3B, PLC/PRF/5, Hep G2) were subjected to detailed cytogenetic analysis with G-banding method after cell cultures. No cloned chromosomal abnormalities were found in the primary hepatoma(below 10%). On the other hand, all hepatoma cell lines were cloned, the specific chromosomal abnormalities in Hep 3B were del(1p21), del(6q14) and t(1 : 11) (p11 : q13). Gen of AMYLA, CGA, SEA and HSTFl were located on 1p21 and 6q14 respectively. SEA and HSTFl were located on 11q13. Regions of chromosome abnormalities in PLC / PRF / 5 were the same found in Hep 3B. Besides, del(1q32) and del(1p32) were also cloned. Gene of CRl and MYCLl were located on 1q32 and 1p32 respectively. The characteristic findings of chromosome abnormalities in Hep G2 were del(1p31) and del (1q22). And GSTl and DAF were located on these regions each other. Del(6q11) and del(1p22) were also found in Hep G2. From the above results, it is presumed that HBV may integrate to AMYlA gene or near this gene and leads to ioss of functions to this gene. And impaired regulation of CGA occurs in next step. SEA, HSTFl and MYCLl oncogenes may act as a progressing factor of tumourgenesis in HBsAg(+) hepatoma, Some factors like chemical agents may cause functional loss of GSTl and DAF at first and functional loss of cell regulation of CGA occurs in next step. SKI oncogene may promote the progression of carinogenesis in this cell line. Whether any causative agents are involed in carcinogenesis of hepatoma, fuctional loss of CGA gene is the most important factor in tumour-genesis in hepatoma.

후천성 면역 결핍증 환장서 발생한 뇌톡소플라즈마증 1례

김보현,이승익,이창훈,차승헌,이태홍,이선희,정주섭,조군제 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

뇌톡소플라즈마증은 후천성면역결핍증 환자에서 발생하는 중추신경계 기회감염증의 가장 흔한 원인 중의 하나이다. 그 빈도는 지역마다 다양하지만 우리나라에서는 매우 드물게 보고되고 있다. 지금까지 우리나라에서 보고된 후천성면역결핍증 환자에서 발생한 뇌톡소플라즈마증 증례들은 모두 혈청학적으로 진단한 것으로 조직학적으로 증명된 경우는 없었다. 저자들은 HIV 감염 후 약 10년 동안 특별한 치료를 받지 않고 지내다 뇌의 다발성 종괴로 내원하여 조직학적으로 확진된 뇌톡소플라즈마증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Toxoplasrnosis is one of the most common opportunistic infection of the central nervous system in patients with acquired immunodeficiency syndrome(AIDS). There have been few reports of cerebral toxoplasmosis in patients with AIDS in Korea. In most cases, the diagnosis was assisted by serology and neuroradiologic findings. Making a reliable diagnosis of acute cerebral toxoplasmosis is difficult in patients with AIDS because of the lack of specificity of serologic data and neuroradiological findings. We report a case of 32-year-old man who presented with decreased mentality and fever. Brain MRI showed multiple ill-defined mass-like lesions in both basal ganglia and right thalamus. Stereotatic brain biopsy revealed small parasitic cysts which were filled with toxoplasmic bradyzoites in inflammatory brain tissue.