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Lee, Heeju,Kim, Kunhee,Woo, Jeong‐,Jun,Jun, Doo‐,Jin,Park, Youngsoo,Kim, Yunsoo,Lee, Hong Won,Cho, Yong Jai,Cho, Hyun Mo WILEY‐VCH Verlag 2011 Chemical vapor deposition Vol.17 No.7
<P><B>Abstract</B></P><P>Thin films of gallium oxide (Ga<SUB>2</SUB>O<SUB>3</SUB>) are prepared by using a new gallium precursor, dimethylgallium isopropoxide (DMGIP), employing both atomic layer deposition (ALD) and metal‐organic (MO)CVD. The gallium precursor DMGIP, a gallium analogue of dimethylaluminum isopropoxide (DMAIP) that has been successfully used for MOCVD and ALD of aluminum oxide, is likewise a non‐pyrophoric liquid at room temperature with a reasonably high vapor pressure. Using water as the oxygen source, DMGIP shows an ALD temperature window in the range 280–300 °C with a growth rate of ∼0.3 Å per cycle. On the other hand, using oxygen as the reactant gas in the MOCVD of Ga<SUB>2</SUB>O<SUB>3</SUB>, films are grown in the temperature range 450–625°C with the apparent activation energy of 225.5 kJ mol<SUP>−1</SUP>. This study shows that DMGIP can be utilized as a new source for the preparation of Ga<SUB>2</SUB>O<SUB>3</SUB> thin films.</P>
Jin-Seok Bae,Jihye Bae,Heeju Woo,Bumjae Lee,Euigyung Jeong 한국탄소학회 2018 Carbon Letters Vol.25 No.-
This study suggests the novel thermoplastic toughening agent, which can be applied in the monomer forms without increasing the viscosity of the epoxy resin and polymerized during the resin curing. The diazide (p-BAB) and dialkyne (SPB) compounds are synthesized and mixed with the epoxy resin and the carbon fiber reinforced epoxy composites are prepared using vacuum infusion process (VIP). Then, flexural and drop weight tests are performed to evaluate the improvement in the toughness of the prepared composites to investigate the potential of the novel toughening agent. When 10 phr of p-BAB and SPB is added, the flexural properties are improved, maintaining the modulus as well as the toughness is improved. Even with a small amount of polytriazolesulfone polymerized, due to the filtering effect of the solid SPB by the layered carbon fabrics during the VIP, the toughening and strengthening effect were observed from the novel toughening agent, which could be added in monomer forms, p-BAB and SPB. This suggests that the novel toughening agent has a potential to be used for the composites prepared from viscosity sensitive process, such as resin transfer molding and VIP.
양모섬유의 세섬화 및 Ionic Liquid와 전처리 조건에 따른 염색특성 연구
우희주,조민희,정재석,박형호,정의경,배진석,Woo, Heeju,Cho, Minhui,Jeong, Jae-Seok,Park, Hyung-Ho,Jeong, Euigyung,Bae, Jin-Seok 한국섬유공학회 2017 한국섬유공학회지 Vol.54 No.3
By producing fine denier wool fibers using the continuous drawing machine, the price can be lowered and high quality can be achieved. In this study, dyeing characteristics were examined in comparison with general fine denier wool which dyeability decreases when drawn. In the scouring and bleaching process to remove impurities of wool fibers and to increase dyeability, the K/S values of yellow and blue colors were decreased by about 0.5 on average. In this regard, the scouring and bleaching process can be skipped since they did not greatly affect the dyeability of the fibers before and after drawing. The dye exhaustion of wool fiber after drawing showed 99.6% on average and the K/S value was increased by an average 2 compared with the fibers before drawing. The dyeing properties of damaged wool fibers after pretreatment using oxidizing agents were investigated when ionic liquid was used. As a result, the dyeability of yellow and red color was improved when ionic liquid was used as solvent while the dyeability of blue color was maintained. It seems that it is necessary to study the correlation between the structure of dyes and ionic liquids used.
Depletion of adipocyte Becn1 leads to lipodystrophy and metabolic dysregulation
Yaechan Song,Young Jin,Yul Ji,Sung Sik Choe,Yong Geun Jeon,Heeju Na,Tae Wook Nam,Hye Jeong Kim,Hahn Nahmgoong,Sung Min Kim,Jae-woo Kim,Ki Taek Nam,Je Kyung Seong,Daehee Hwang,Chan Bae Park,In Hye Lee 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Macroautophagy is a catabolic process that delivers damaged and unnecessary cytosolic contents to lysosomes for removal of defective subcellular organelles and proteins. Becn1 is a key regulator of autophagy, forming a complex with class III phosphatidylinositol 3-kinase (PI3K-III) to initiate autophagosome formation. Although Becn1 has been implicated in numerous diseases such as cancer, aging, and neurodegenerative disease, its function in mature adipocytes remains elusive. In this study, we implemented Adipoq-Cre to generate adipocyte-specific Becn1 KO (BaKO) mice to identify the function of autophagy in adipose tissue homeostasis. BaKO mice naturally developed severe lipodystrophy and metabolic dysregulation, which were exacerbated upon high dietary fat intake. These mice also acquired adipose tissue inflammation, hepatic steatosis, and insulin resistance which advanced to early mortality. Immortalized stromal vascular cells (imSVCs) were established in-vitro to conditionally knock-out Becn1 upon tamoxifen treatment. Ablation of Becn1 in adipocytes led to programmed cell death in a cell-autonomous manner, accompanied by elevated endoplasmic reticulum (ER) stress gene expression. Furthermore, we observed that Becn1 depletion sensitized mature adipocytes to ER stress through activation of protein kinase R-like ER kinase (PERK) – eukaryotic initiation factor 2α (eiF2α) axis. This led to excessive unfolded protein response (UPR) and accelerated cell death through notable induction of C/EBP homologous protein (CHOP) and Bax expression. Taken together, these data suggest that adipocyte-Becn1 would serve as a crucial player for adipocyte survival and adipose tissue homeostasis.