서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조

서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국하천호수학회 2014 생태와 환경 Vol.47 No.special

In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.

키틴에 의한 염색폐수 색도처리에 관한 연구

이한섭 龍仁大學校 自然科學硏究所 1999 自然科學硏究所論文誌 Vol.4 No.1

Chitin, which are known as final biomasses, a kind of natural resources, and chemically structural properties of chitin and treatment system using chitin for dyeing waste water were investigated. Experimental results showed that the specific surface area were increased and particle size were decreased a little in accordance with the repeating number of treatments, and chitin Ⅰ, treated 4 times, with specific surface area 34.82 ㎡/g and geometric mean particle size 18.25 ㎛ was manufactured. The specific surface area was increased because chains of chitin molecules were cut, and therefore its low molecular weights were resulted. In order to understand the adsorption capacity of water, tea bag method was utilized. It was observed that the maximum water content reached above 20 minutes after dipping in distilled water and the water contents were increased with the repeating number of treatments of chitin. The removal efficiency of suspended solids and the variations of turbidity showed high efficiency regardless of the the repeating number of treatments of chitin, and COD values treated with chitin were rised at the beginning on the contrary but the removal efficiency on COD was increased in proportion to the repeating number of treatments of chitin in case of liquid separated by filtration. The repeating number of treatments of chitin had a little effect on the removal efficiency of colority but stirring speed had a great effect on this, which are most hard to treat dyeing waste water. Colority was decreased to 40~60 ADMI as much as the application of effluence standard(60~80 ADMI), and chitin Ⅰ showed the good removal efficiency of colority than that of commercial Aldrich.

아닐린으로부터 탈아미노반응과 니트로반응을 이용한 이소퀴놀린(Isoquinoline) 유도체의 합성

이한섭,최성부 용인대학교 자연과학연구소 2008 自然科學硏究所論文誌 Vol.13 No.1

This study is to develop a new synthetic method for the nitroarenes vis non-electrophilic substitution. Direct nitration at the C-1 position of isoquinoline has never been reported and substitution in isoquionoline under the normal nitration condition occurs at C-5 and C-8. We have demonstrated a facile one-step sythetic method for the nitration of isoqunolines at the C-1 position, which involves the electrophilic attack of a DMSO-Ac2O complex, followed by nucleophilic addition of nitrate ion the this intermeddiate. Since the reaction is simple and mild, this method has preparative merit since 1-nitroisoqunolines are nto readily accessible by other methods. Application to the synthesis of poly nitroarenes from the corresponding anilines was also described.

천연 Gum의 생체적합성에 대한 연구

이한섭,최성부 용인대학교 자연과학연구소 2008 自然科學硏究所論文誌 Vol.13 No.1

Natural gum films were prepared by solution blending method in the weight ratio of natural gums(Xanthan, Locust bean and Guar) for the purpose of useful bio-compatibility materials. The possibility of bio-compatibility materials, which prepared from natural gums as a skin substitute of rats were evaluated by measuring biodegradability. This biodegradable films were inserted in the back of rats and their of biodegradability were investigated by hematological change evaluation as a function of time to the bio-transformation. These values of bio-compatibility materials films, which prepared from natural gums measured in this study were some stable results at short period with those of ideal skin with bio-compatibility materials.

Glutaraldehyde를 이용한 설파제의 합성과 지속성에 관한 연구

이한섭,최성부 용인대학교 자연과학연구소 2007 自然科學硏究所論文誌 Vol.12 No.1

Dual actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against Gram(+) and Gram(-) of 4 strains and a long durability supposing that the stomach and blood.

탄화수소계 대체세정제를 이용한 스크린 인쇄 세정효율에 관한 연구

이한섭 龍仁大學校 1997 용인대학교 논문집 Vol.14 No.-

Many alternatives cleanser to 1,1,1-TCE & CFC-113 used as cleanser for industrial parts are developed because the cleanser is scheduled to phaseout after 1996. Also, existing cleaner using screen printing are the organic solvents including aromatic compounds carried with poisonous and stench. Besides, cleaning method of current screen printing are for the most part mixed cleaning method of dipping and polish using duster. Accordingly, it had a bad effect to the working environment and the workers body. Therefore, using alternative hydrocarbon cleanser to 1,1,1-TCE & CFC-113 used as cleanser for industrial parts be substituted for existing cleanser against screen printing ink measured the cleaning efficiency according to gravimetric analysis method and property change of gassamer according to Image Analyzer.

환경친화성을 고려한 인쇄용 감광성 고분자 특성 연구

이한섭 龍仁大學校 2003 용인대학교 논문집 Vol.21 No.-

Naphthoquinone diazide derivatives members of quinone diazide compound that are utilizable as photosensitive polymer material were synthesized, and photoresist were prepared by mixing these derivatives with a matrix resin at various weight ratios. Photosensitive characteristics of photoresist were studied by examining UV and IR. relative sensitivity using a Gray scale method, and SEM to analyze if they can be used as photosensitive material in printing process. Experimental results showed that, by UV, NQD derivatives were photo-converted and developer-soluble photoresist were produced. The mixing ratio of 1:4(by mass) of NQD+ballast and m-cresol novolak gave rise to the highest dissolution rate. In addition, photoresist obtained at this condition resulted in the most superior sensitivity and contrast.

Sulfa제를 사용한 합성 향균 polyacrylic acid의 향균 효과

이한섭,강안수 용인대학교 자연과학연구소 2002 自然科學硏究所論文誌 Vol.7 No.1

Antibiotics polymer prepared by chemical bonding and simple blending of antibacterial into polymers have attracted much interest because of their long-lasting and antibacterial activity. Antibiotics polymer can significantly reduce losses associated with dissolution, photolytic decomposition and volatillization. Further more, increased efficiency safety and selectivity are additional benefits which may be realized. In this study, Antibiotics polymer was synthesized by chemical reaction of polyacrylic acid with sulfamethazine by N,N'-dicyclohexylcarbodiimide(DCC) method. Antibacterial susceptibility was determined against Streptococcus pyrogenes [gram(+)]and Esherichia. coli.[gram(-)] using a standardized disc test. As a result, the synthetic antibiotics polymer exhibited the broad susceptibility against Streptococcus pyrogenes and Esherichia. coli. Especially, the antibiotic effect of antibacterial polymer against Gram negative(Esherichia. coli) was much stronger than that against Gram positive(Streptococcus pyrogenes).

확산계수에 미치는 용매의 영향

이한섭,강안수,강삼룡 明知大學校 産業技術硏究所 1984 産業技術硏究所論文集 Vol.3 No.-

Diffusion coefficients of dye was increased by adding organic components and electrolytes as solvent to dye-water system. We measured diffusion coefficients by treating the ternary system of dye-solvent-water as a pseudo-binary system of dye-water and solvent. All experiments were made with the diaphragm cell of Whatman 42 filter paper and sintered glass when solvent was organic components and electrolytes respectively. The experimental results showed that diffusion coefficients of dye nearly agreed with the approximate equation related to the solubility of dye. Diffusion coefficients of dye were increased when solubility of dye to the water was larger than that of organic component to the water. There was similar tendency between diffusion coefficients of orange Ⅱ and that of electrolyte when solvents were electrolytes. In order to increase diffusion coefficients of dye, electrolytes were more favorable than organic components as solvent. But in the case of urea as solvent, diffusion coefficients of orange Ⅱ were increased maximum seven times.