서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조

서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국하천호수학회 2014 생태와 환경 Vol.47 No.special

In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.

아닐린으로부터 탈아미노반응과 니트로반응을 이용한 이소퀴놀린(Isoquinoline) 유도체의 합성

이한섭,최성부 용인대학교 자연과학연구소 2008 自然科學硏究所論文誌 Vol.13 No.1

This study is to develop a new synthetic method for the nitroarenes vis non-electrophilic substitution. Direct nitration at the C-1 position of isoquinoline has never been reported and substitution in isoquionoline under the normal nitration condition occurs at C-5 and C-8. We have demonstrated a facile one-step sythetic method for the nitration of isoqunolines at the C-1 position, which involves the electrophilic attack of a DMSO-Ac2O complex, followed by nucleophilic addition of nitrate ion the this intermeddiate. Since the reaction is simple and mild, this method has preparative merit since 1-nitroisoqunolines are nto readily accessible by other methods. Application to the synthesis of poly nitroarenes from the corresponding anilines was also described.

BOD_5측정의 영향인자에 관한 연구

이한섭 용인대학교 자연과학연구소 2000 自然科學硏究所論文誌 Vol.5 No.1

This study was showed to accuracy and confidence of BOD5 measurement in sewage and wastewater analysis. Under the influence of factor to BOD5 with variation of pH, light and incubation temperatur was measured. The result of pH and light was not affected of BOD5 value by same condition, but incubation temperatur was affected in 20 ℃ basis with ±10 ℃ to BOD5 value increase and decrease ± 15 %, At same condition, the BOD5 value of one sample raised degree with several times measurement and step dilution, but a low confience.

체류시간 및 하수분할유입에 따른 질소 제거효율

이한섭 용인대학교 2007 용인대학교 논문집 Vol.25 No.-

The amount of waste water generated in Korea is constantly an increasing trend in proportion to economic growth, and the conventional activated sludge process is widely being used for general waste water treatment. But the ministry of environment is rapidly strengthening the treatment standards of N and P (less than 20㎎/L of N, 2㎎/L of P from Jan. 1, 2008 in the whole nation) to prevent the eutrophication of lake water, and therefore highly advanced treatment technology is required not only in the existing treatment plants where the activated sludge process is being used, but also in newly constructed treatment plants for the treatment of N and P. This study is aimed at highly operating the engineering technology method was developed by domestic D company to eliminate N at the same time. Experiments were conducted in the G treatment plant located in Y city. The treatment process of the bioreactor was started from the principal equipment for the elimination of N, nitrification and the elimination of organic compounds. And it has an internal recycle piping from the end of the aerobic tank to the anoxic tank and external recycle piping from the final settling basin to the denitrification tank. By experiment of 4 types separate inflow of waste water to the denitrification tank and the anaerobic tank, and changes in staying time at the anoxic tank and the aerobic tank, the elimination of organic compounds in each type and the relationship in the efficiency between the elimination of N were researched.

천연 Gum의 생체적합성에 대한 연구

이한섭,최성부 용인대학교 자연과학연구소 2008 自然科學硏究所論文誌 Vol.13 No.1

Natural gum films were prepared by solution blending method in the weight ratio of natural gums(Xanthan, Locust bean and Guar) for the purpose of useful bio-compatibility materials. The possibility of bio-compatibility materials, which prepared from natural gums as a skin substitute of rats were evaluated by measuring biodegradability. This biodegradable films were inserted in the back of rats and their of biodegradability were investigated by hematological change evaluation as a function of time to the bio-transformation. These values of bio-compatibility materials films, which prepared from natural gums measured in this study were some stable results at short period with those of ideal skin with bio-compatibility materials.

점토성분에 의한 Pb^2+ 및 Cd^2+의 흡착특성에 관한 연구

이한섭 龍仁大學校 自然科學硏究所 1999 自然科學硏究所論文誌 Vol.4 No.2

This study deals with the adsorption characteristics of heavy metal by adsorbents, kaolinite, momtmollinite and bentonite in aquous solution. The adsorption of Pb2+ and Cd2+ to eqilibrium adsorption reached approximately 1 hour. In acid pH range were more favorable increasing adsorptivity. Generally, the adsortivity of Pb2+ besser than that of Cd2+ .The adsorption isotherm equation of Pb2+ agreed with the Freundlich isotherm, the Freundlich constant(1/n) of kaolinite, montmollinite and bentorlite was 0.195, 0.274 and 0.34. Its value meaned a good adsorbent for the remove of Pb2+.

지방족 C -아민류 추출제에 의한 유기산의 반응 추출

이한섭,강안수,류운형 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

The effects of extractant species, concentration, solvent and temperature on the degree of extraction were investigated, and also the effects of concentration of stripping phase and temperature on the degree of re-extraction were investigated in physical and reactive extraction system using equilibrium extraction unit. The used organic acids were acrylic acid, methacrylic acid, pyruvic acid, α-ketoglutaric acid, and the extractants were n-octylamine(OA, primary amine), di-n-octylamine(DOA, secondary amine), tri-n-octylamine(TOA, tertiary amine) and Aliquat 336. (TOMAC, quaternary ammonium salt). N-butylacetate(n-BAc), methyl-isobutyl-ketone(MIBK), chloroform, xylene and kerosene were used as solvents. The effect of the degree of re-extraction was investigated using alkaline solution of NaOH and Na₂CO₃. We found that the degree of extraction for reactive extraction was 2∼9 times than that for physical extraction and that the effect of extractants on the degree of extraction of organic acid was the order of OA>TOMA>DOA>TOA. And the degree of extraction was increased with increasing the concentration of extractants. In solvent effect, solubility parameter was more effective than dielectric constant of solvent, and the degree of extraction increased as the difference of solubility parameter of solvent and solute decreased, therefore the order was kerosene>xylene>chloroform>MIBK>n-BAc. Also, the degree of re-extraction increased with decreasing basicity of stripping phase, therefore, the degree of re-extraction for re-extraction of organic acid was higher in Na₂CO₃solution than in NaOH solution. As a result of the effect of temperature, the degree of extraction was decreased and re-extraction was increased with increasing temperature, respectively.

Glutaraldehyde를 이용한 설파제의 합성과 지속성에 관한 연구

이한섭,최성부 용인대학교 자연과학연구소 2007 自然科學硏究所論文誌 Vol.12 No.1

Dual actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against Gram(+) and Gram(-) of 4 strains and a long durability supposing that the stomach and blood.

확산계수에 미치는 용매의 영향

이한섭,강안수,강삼룡 明知大學校 産業技術硏究所 1984 産業技術硏究所論文集 Vol.3 No.-

Diffusion coefficients of dye was increased by adding organic components and electrolytes as solvent to dye-water system. We measured diffusion coefficients by treating the ternary system of dye-solvent-water as a pseudo-binary system of dye-water and solvent. All experiments were made with the diaphragm cell of Whatman 42 filter paper and sintered glass when solvent was organic components and electrolytes respectively. The experimental results showed that diffusion coefficients of dye nearly agreed with the approximate equation related to the solubility of dye. Diffusion coefficients of dye were increased when solubility of dye to the water was larger than that of organic component to the water. There was similar tendency between diffusion coefficients of orange Ⅱ and that of electrolyte when solvents were electrolytes. In order to increase diffusion coefficients of dye, electrolytes were more favorable than organic components as solvent. But in the case of urea as solvent, diffusion coefficients of orange Ⅱ were increased maximum seven times.