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( Haibo Yuan ),( Yanfeng Liu ),( Xueqin Lv ),( Jianghua Li ),( Guocheng Du ),( Zhongping Shi ),( Long Liu ) 한국미생물 · 생명공학회 2018 Journal of microbiology and biotechnology Vol.28 No.12
The compound 2,5-furandicarboxylic acid (FDCA), an important bio-based monomer for the production of various polymers, can be obtained from 5-hydroxymethylfurfural (HMF). However, efficient production of FDCA from HMF via biocatalysis has not been well studied. In this study, we report the identification of key genes that are involved in FDCA synthesis and then the engineering of Raoultella ornithinolytica BF60 for biocatalytic oxidation of HMF to FDCA using its resting cells. Specifically, previously unknown candidate genes, adhP3 and alkR, which were responsible for the reduction of HMF to the undesired product 2,5- bis(hydroxymethyl)furan (HMF alcohol), were identified by transcriptomic analysis. Combinatorial deletion of these two genes resulted in 85.7% reduction in HMF alcohol formation and 23.7% improvement in FDCA production (242.0 mM). Subsequently, an aldehyde dehydrogenase, AldH, which was responsible for the oxidation of the intermediate 5-formyl-2-furoic acid (FFA) to FDCA, was identified and characterized. Finally, FDCA production was further improved by overexpressing AldH, resulting in a 96.2% yield of 264.7 mM FDCA. Importantly, the identification of these key genes not only contributes to our understanding of the FDCA synthesis pathway in R. ornithinolytica BF60 but also allows for improved FDCA production efficiency. Moreover, this work is likely to provide a valuable reference for producing other furanic chemicals.
A Theoretical Framework on Logistics Outsourcing Performance Appraisal
Haibo Yuan,Hui Chen 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10
The wroldwide usage and importance of logistics outsourcing has grown dramatically over the last decades and will continue to do so, so clearly understanding the drivers of logistics outsourcing performance is critical knowledge for managers to have in today"s competitive business environment. In earlier time, firms aiming purely at cost reductions in the logistics outsourcing arrangement but now they emphasize other aspects. In this paper, by analyzing the benefits and risks of logistics outsourcing, we propose a method of how to make the decison of finding the optimal outsourcing scopes with respective firm. Based on the discussion of KSF and KPI of logistics outsourcing, we develop a logistics outsourcing performance appraisal system from the perspective of balance scorecard. We also address the challenges, future trends and some additional research needs in this area.
Distributed Finite-time Regulation of a Class of Networked Heterogeneous Multi-agent Systems
Yuan Liu,Shicheng Wang,Haibo Min,Long Ma,Dacheng Luo 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.1
In this paper, we investigate the finite-time regulation problem for heterogeneous multiagent system composed of linear first-order, second-order integrator agents and nonlinear Euler- Lagrange (EL) dynamical agents. Based on homogeneity approach, a continuous finite-time controller is designed. A distinctive feature of this work is to address the finite-time consensus problem of firstorder, second-order integrator agents and nonlinear EL agents in a unified theoretical framework. Simulation results are also provided to illustrate the effectiveness of the controller.
Jiankun Xiong,Haibo Zhang,Fuheng Nie,Fen He,Jianping Yang,Zhan Hu,Zhongbo Wen,Haiyan Zhao,Xinjian Yuan 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7
The formation mechanisms for two carbides with co-existence and increasing stacking faults nearby the carbides duringsurfacing welding were investigated in this study. The results indicated that the surfacing layer had a two-phase structure ofa matrix phase and a second phase, the density of the second phase was relatively small and the second phase was discontinuous,by contrast with the as-received welding wire. Relatively uniform microstructure of surfacing layer and the weldinginterface without melting of base metal were obtained, resulting in an inapparent change in the microhardness. A few carbideswith blocky shape were identified in the surfacing layer. The mechanisms for (Cr,Co)23C6 of face-centered cubic crystalstructure co-existing with (Cr,Co)7C3 of hexagonal close-packed crystal structure and (Cr,Co)23C6 subsequently forming closeto the pre-formed (Cr,Co)7C3 during the cooling process were discussed in alloying element, calculated equilibrium phasediagram, Gibbs energy, etc. The relatively higher density of the stacking fault present around the carbides was understoodfrom forming energy of stacking faults.
Yeast Extract: Characteristics, Production, Applications and Future Perspectives
Tao Zekun,Yuan Haibo,Liu Meng,Liu Qian,Zhang Siyi,Liu Hongling,Jiang Yi,Huang Di,Wang Tengfei 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.2
Yeast extract is a product prepared mainly from waste brewer’s yeast, which is rich in nucleotides, proteins, amino acids, sugars and a variety of trace elements, and has the advantages of low production cost and abundant supply of raw material. Consequently, yeast extracts are widely used in various fields as animal feed additives, food flavoring agents and additives, cosmetic supplements, and microbial fermentation media; however, their full potential has not yet been realized. To improve understanding of current research knowledge, this review summarizes the ingredients, production technology, and applications of yeast extracts, and discusses the relationship between their properties and applications. Developmental trends and future prospects of yeast extract are also previewed, with the aim of providing a theoretical basis for the development and expansion of future applications.
Prediction of black tea fermentation quality indices using NIRS and nonlinear tools
Chunwang Dong,Hongkai Zhu,Jinjin Wang,Haibo Yuan,Jiewen Zhao,Quansheng Chen 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.4
Catechin content, the ratio of tea polyphenols and free amino acids (TP/FAA), as well as the ratio of theaflavins and thearubigins (TFs/TRs) are important biochemical indicators to evaluate fermentation quality. To achieve rapid determination of such biochemical indicators, synergy interval partial least square and extreme learning machine combined with an adaptive boosting algorithm, Si-ELM-AdaBoost algorithm, were used to establish quantitative analysis models between near infrared spectroscopy (NIRS) and catechin content and between TFs/TRs and TP/FAA, respectively. The results showed that prediction performance of the Si-ELM-AdaBoost mixed algorithm is superior than that of other models. The prediction results with root-mean-square error of prediction ranged from 0.006 to 0.563, the ratio performance deviation values exceeded 2.5, and predictive correlation coefficient values exceeded 0.9 in the prediction model of each biochemical indicator. NIRS combined with Si-ELMAdaBoost mixed algorithm could be utilized for online monitoring of black tea fermentation. Meanwhile, the AdaBoost algorithm effectively improved the accuracy of the ELM model and could better approach the nonlinear continuous function.
Effects of solvent properties on cationic dyeing process of acrylic yarn
Zhengyu Zhang,Chunling Zheng,Ailing Yuan,Haibo Wang,Ling Zhu,Hong Xu 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.4
Cationic dye is a special dye for acrylics, but it is very difficult in dyeing through the core. In practice,the price of a special leveling agent for acrylic fiber is high, and uniform staining is poor. By mixing a number of organicsolvents in the dye bath, we can improve the structure of fibers and their deep-dyeing. We used n-propanol, isopropanoland benzyl alcohol as organic solvents, by adjusting the pH value and the appropriate temperature, and with specialdepth and leveling agent for dyeing soaping fastness contrast, to find economically viable process conditions.
Multimodal Sensing with a Three-Dimensional Piezoresistive Structure
Won, Sang Min,Wang, Heling,Kim, Bong Hoon,Lee, KunHyuck,Jang, Hokyung,Kwon, Kyeongha,Han, Mengdi,Crawford, Kaitlyn E.,Li, Haibo,Lee, Yechan,Yuan, Xuebo,Kim, Sung Bong,Oh, Yong Suk,Jang, Woo Jin,Lee, J American Chemical Society 2019 ACS NANO Vol.13 No.10
<P>Sensors that reproduce the complex characteristics of cutaneous receptors in the skin have important potential in the context of artificial systems for controlled interactions with the physical environment. Multimodal responses with high sensitivity and wide dynamic range are essential for many such applications. This report introduces a simple, three-dimensional type of microelectromechanical sensor that incorporates monocrystalline silicon nanomembranes as piezoresistive elements in a configuration that enables separate, simultaneous measurements of multiple mechanical stimuli, such as normal force, shear force, and bending, along with temperature. The technology provides high sensitivity measurements with millisecond response times, as supported by quantitative simulations. The fabrication and assembly processes allow scalable production of interconnected arrays of such devices with capabilities in spatiotemporal mapping. Integration with wireless data recording and transmission electronics allows operation with standard consumer devices.</P> [FIG OMISSION]</BR>