Study of Several Silica Properties Influence on Sapphire CMP

Wang, Haibo,Zhang, Zhongxiang,Lu, Shibin The Korean Institute of Electrical Engineers 2018 Journal of Electrical Engineering & Technology Vol.13 No.2

Colloid silica using as abrasive for polishing sapphire has been extensively studied, which mechanism has also been deeply discussed. However, by the requirement of application enlargement and cost reduction, some new problems appear such as silica service life time, particle diameter mixing, etc. In this paper, several influences of colloid silica usage on sapphire CMP are examined. Results show particle diameter and concentration, pH value, service life time, particle diameter mixing heavily influence removal rate. Further analysis discloses there are two main effect aspects which are quantity of hydroxyl group, contact area for abrasive density stacking between abrasive and sapphire. Based on the discussions, a dynamic process of sapphire polishing is proposed.

Study of Several Silica Properties Influence on Sapphire CMP

Haibo Wang,Zhongxiang Zhang,Shibin Lu 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.2

Colloid silica using as abrasive for polishing sapphire has been extensively studied, which mechanism has also been deeply discussed. However, by the requirement of application enlargement and cost reduction, some new problems appear such as silica service life time, particle diameter mixing, etc. In this paper, several influences of colloid silica usage on sapphire CMP are examined. Results show particle diameter and concentration, pH value, service life time, particle diameter mixing heavily influence removal rate. Further analysis discloses there are two main effect aspects which are quantity of hydroxyl group, contact area for abrasive density stacking between abrasive and sapphire. Based on the discussions, a dynamic process of sapphire polishing is proposed.

Strong, and recyclable thermosets cross-linked by MWCNT/poly(aryl ether ketone) containing furan based on Diels-Alder cycloaddition

Wang Yongpeng,Wang Heng,Zhang Qingwen,Zhang Yingyuan,Yan Pengtao,Liu Mengzhu,Zhang Haibo 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.8

Multi-walked carbon nanotube (MWCNT)/poly(aryl ether ketone) networks cross-linked by Diels-Alder cycloaddition possess outstanding mechanical and rheological properties. Poly(aryl ether ketone) containing pendant furan (PAEK-Fu) was synthesized, which had excellent thermal and mechanical properties, and a series of cross-linked materials with reversible covalent cross-linked crosslinking network were synthesized through a furan/MWCNTs Diels-Alder (D-A) reaction between PAEK-Fu and MWCNTs. Thermal and mechanical properties for MWCNT/PAEK-Fu composites were studied, and after crosslinking, MWCNT/PAEK-Fu composites exhibited good flexibility and resistance against organic solvents. After heating to 180 °C, the cross-linked MWCNT/PAEK-Fu composite membranes could be dissolved in NMP. This work demonstrates that the poly(aryl ether ketone)s can be made into recyclable thermoset materials using the concept of associative dynamic bonding. Given the dramatically increasing interest in environmentally sustainable materials, this MWCNT/poly(aryl ether ketone) interaction mode provides a robust approach to high performance engineering plastics with improved performance compared with the thermoplastic counterparts.

Molecular cloning and functional characterization of Jatropha curcas NCED3 involved in cold resistance

Wang Haibo,Guo Junyun 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.1

The abscisic acid (ABA) plays a crucial role not only in plant development but also in adaptive responses to biotic and abiotic stresses. 9-cis-epoxycarotenoid dioxygenase (NCED), a key rate-limiting enzyme in ABA biosynthesis in plants, is involved in the response of plants to stress. To better understand the roles of ABA and its interactions during cold stress in Jatropha curcas, the JcNCED3 gene was cloned from J. curcas, and its overexpression was functionally verified in yeast and Arabidopsis thaliana. The full-length cDNA of JcNCED3 was 2450 bp and contained an entire open reading frame (ORF) of 1770 bp that encodes a polypeptide of 589 amino acids with a theoretical molecular weight of 65.45 kDa and pI value of 6.97. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis revealed that JcNCED3 was specifically expressed in different organs, abundantly in leaves and cotyledons, but scarcely in stems. The expression of the JcNCED3 gene was remarkably cold-induced in stems and roots, reaching its highest levels after 3 h (1.23-fold) of chilling stress in stems. Interestingly, overexpression of JcNCED3 in yeast could notably enhance the cold resistance of the INVSc1 host strain. Furthermore, transgenic Arabidopsis also showed stronger resistance to cold than the control. The results of this study might provide a theoretical foundation for further studies on the putative application potential of JcNCED3-related genetic engineering in J. curcas.

Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus <i>Paecilomyces variotii</i> J08NF-1

Wang, Haibo,Hong, Jongki,Yin, Jun,Moon, Hyung Ryong,Liu, Yonghong,Wei, Xiaoyi,Oh, Dong-Chan,Jung, Jee H. American Chemical Society 2015 Journal of natural products Vol.78 No.11

Experimental Study on Dynamic Interaction between Large U-Shape Aqueduct and Water

Haibo Wang,Chunlei Li,Lijun Zhao 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.3

Hydrodynamic interaction between water and structure plays an important role in the evaluation of seismic response of aqueducts in area of high seismicity. This interaction differs in axial, lateral and vertical direction of aqueduct. Both impulsive and convective effects of water exist in lateral direction. In presented study, shaking table tests were conducted with a1/10 model of U-shape aqueduct, of 30 m long, to study the hydrodynamic interaction. With the analyses of aqueduct and water responses to stationary White Noise excitations as well as non-stationary excitations, impulsive and convective effects of water were deduced quantitatively. Characteristic frequencies and corresponding modes of aqueduct were identified with the transfer functions of acceleration, sloshing frequencies in lateral direction were recognized with the transfer functions of seat force. Impulsive mass was deduced from the alteration in fundamental frequency and the corresponding modal seat forces of the aqueduct with and without water. Convective mass was obtained from the wave height of sloshing and lateral seat forces recorded, or the lateral modal seat force and damping ratio. Comparison was made with those given in simplified methods for rigid structure. Observed hydrodynamic pressure on the structure in the test was smaller than that based on the rigid assumption.

Efficacy of nano-drugs in muscle injury rehabilitation and fatigue relief

Zicheng Wang,Yanqing Liu,Haibo Wang,Dai Liu,Niuniu Yang,Mengying Lv Techno-Press 2023 Advances in nano research Vol.14 No.1

Gold nanoparticles have recognized a promising drug carriers in many diseases. These nanoparticles could carry anti-inflammatory drugs in the case of muscle injury and for fatigue relief. On the other hand, specific surface of this kind of nanoparticles could be critical in amount of drug they could carry. Therefore, in this study, we explore different methodology and influencing parameters on the specific surface of gold nanoparticles. After specifying the main parameters, different machine learning and artificial neural network are adopted to model the effects of different parameters. Furthermore, response surface methodology is utilized to obtain a quadrilateral relationship between different parameters and specific surface. The results indicate that concentration of the gold salt solution is the most important parameter in increasing the size of gold nanoparticle and, as a consequence, increasing specific surface. Moreover, the ability of gold nanoparticles in prolonging retention of the drugs is discussed in detail.

Impact of Grafting Density on the Self-Assembly and Hydrophilicity of Succinylated Collagen

Wenxin Wang,Feiyi Shu,Lingyu Pan,Shanshan Huang,Xiao Tu,Ping Li,Siman Li,Yuanyuan Li,Chengzhi Xu,Yang Sun,Juntao Zhang,Haibo Wang 한국고분자학회 2020 Macromolecular Research Vol.28 No.6

Modification of protein could give their new functionality but would affect their intrinsic property and activity. In this paper, a series of succinylated collagen (SCol(n/1)) (n≥1) were prepared by modification of collagen with succinic anhydride at different molar ratio to amino groups amount of collagen. The impact of grafting density on the intrinsic self-assembly and additional hydrophilicity of succinylated collagen was explored. The results revealed that excessive grafting density of succinylated collagen would improve their hydrophilicity but weaken their self-assembly property, although the triple helix of collagen could be reserved after succinylation. SCol(1/1) (grafting density of 17%) with self-assembly property and good hydrophilicity was chosen to compare with native collagen. Compared to native collagen, thermostability of SCol(1/1) decreased slightly, however, SCol(1/1) could form softer hydrogel, which was more favorable for the proliferation of NIH/3 T3. The present work would help us to further understand the importance of grafting density for the design of modified collagen with intrinsic self-assembly property and additional new functionality.

Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition

Xian Wang,Shaolei Ma,Haibo Wu,Xiaofeng Shen,Shiqin Xu,Xirong Guo,Maria L Bolick,Shizheng Wu,Fuzhou Wang 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

Our previous works disclosed the contributing role of macrophage migration inhibitory factor (MIF) and dopaminergic inhibition by lysine dimethyltransferase G9a/Glp complex in peripheral nerve injury-induced hypersensitivity. We herein propose that the proinflammatory cytokine MIF participates in the regulation of neuropathic hypersensitivity by interacting with and suppressing the descending dopaminergic system. The lumbar spinal cord (L-SC) and ventral tegmental area (VTA) are two major locations with significant upregulation of MIF after chronic constriction injury (CCI) of the sciatic nerve, and they display time-dependent changes, along with a behavioral trajectory. Correspondingly, dopamine (DA) content shows the reverse characteristic change to MIF with a time-dependent curve in post-surgical behavior. The levels of both MIF and DA are reversed by the MIF tautomerase inhibitor ISO-1, and a negative relationship exists between MIF and DA. The reversed role of ISO-1 also affects tyrosine hydroxylase expression. Furthermore, CCI induces Th promoter CpG site methylation in the L-SC and VTA areas, and this effect could be abated by ISO-1 administration. G9a/SUV39H1 and H3K9me2/H3K9me3 enrichment within the Th promoter region following CCI in the L-SC and VTA was also decreased by ISO-1. In cultured dopaminergic neurons, rMIF enhanced the recruitment of G9a and SUV39H1, followed by an increase in H3K9me2/H3K9me3. These molecular changes correspondingly exhibited alterations in Th promoter CpG site methylation and pain behaviors. In summary, MIF functions as a braking factor in curbing dopaminergic descending inhibition in peripheral nerve injury-induced hypersensitivity by mediating Th gene methylation through G9a/SUV39H1-associated H3K9 methylation.

Research on the Tensile Mechanical Properties and Fracture Characteristics of GFRP Mortar Tubes under Impact Loads

Hao Wang,Qi Zong,Haibo Wang 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.4

To investigate the protective effect of glass fiber-reinforced plastic (GFRP) pipes on cement mortar, dynamic splitting tests were carried out on cement mortar and GFRP-mortar pipe specimens by using a 74 mm diameter Hopkinson pressure bar (SHPB) test device combined with a high-speed video camera device to obtain the crack expansion process and rupture and fragmentation morphology of the specimens. The results show that the tensile strength of cement mortar rings is lower and that the stress?strain curve is single-peaked. Compared with cement mortar rings, the tensile strength of GFRP-mortar ring specimens increases significantly, and the stress-strain curve is bimodal. For 0.5 MPa air pressure and wall thicknesses of 0, 2, 3, and 4 mm, the hollow rate of the 0.187 specimen peak stress is 3.21, 1.02, 1.05, and 1.26 times that of the 0.292 specimen. For 0.5 MPa air pressure and a hollow rate of 0.187, the wall thickness of the 2, 3, and 4 mm specimen peak stress is 1.06, 1.31, and 1.69 times that of the 0 mm specimen. The increase in the wall thickness, the decrease in the hollow rate and the increase in the strain rate make the dynamic tensile strength of the specimens increase. The dynamic modulus of elasticity of the GFRP-mortar pipe specimens was lower than that of the mortar specimens, and the increase in strain rate and the thickness of the GFRP pipe wall resulted in an increase in the dynamic modulus of elasticity of the specimens. The cement mortar specimen under impact load was split and tensile damage occurred; the GFRP-mortar specimen suffered tensile damage at the two ends of the applied force, and the upper and lower ends were crushed. With the increase in the strain rate, the GFRP-mortar specimens transitioned from cracks to the formation of “V” area damage, and the specimen crushing degree increased, but the existence of GFRP pipe can have a protective effect on the mortar, reducing the degree of specimen rupture and crushing. The increase in the hollow ratio reduces the ability of the specimen to resist the external load, and the degree of specimen rupture and fragmentation increases.