폐경기 여성에서 호르몬 대치 요법시 병행 투여된 프로제스토젠 투여 방법에 따른 골대사의 생화학적 지표에 미치는 영향

이권해,강선영,임경빈,이해혁,구도형,이석민 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Purpose : To evaluate the impact of added progestogen on biochemical markers of the bone turnover undergoing hormone replacement therapy in the postmenopausal women. Materials and Methods : There are 71 postmentopausal women who are divided into three groups (Group I, Group II, Group III). Group I(continuous combined)is given conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 2.5mg, day 1-30), Group II(unopposed estrogen) is given conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 5mg, day 1-12). And there were measured serum osteocalcin, serum total alkaline phosphatase and urinary deoxypyridinoline excretion before starting hormone replacement therapy and 12 months later. Results : The serum osteocalcin, serum total alkaline phosphatase and urinary deoxypyridinoline excretion significantly decreased after hormone replacement therapy (Group, I, II, III). And there was no significance in decreases in biochemical markers of the bone turnover among three groups. Conclusions : It was concluded that the impact of added progestogen on the biochemical markers of the bone turnover undergoing hormone replaced therapy in postmenopausal women was not significant than nothing added group. Thus we concluded that progestogen was not impact on decreasing on the biochemical markers of the bone turnover in postmenopausal women undergoing hormone replacement therapy.

산업보건관리자를 위한 소음성 난청 예방지침서의 개발

이원철,유경혜,장성실,이세훈,구정완,김현욱,노영만,이경재,김형아 가톨릭 대학 산업의학 쎈타 산업의학연구소 1996 韓國의 産業醫學 Vol.35 No.1

Occupational hearing loss became the leading occupational disease by constioution 56% of all work-related diseases in Korea. However, the prevalance rates showed wide variations among the specific medical examination providers and were very low(0.8-1.4%) compared with those 8.4% in Japan. The sources of these variations was regarded in the preview study as 1) Employee audometric estings were primarily conducted by nurses and nurse-aids who had no formal training for audiometry; 2) althought audiometric testing equipment used by the spedific medical examination providers, it should be periodically calibrated, a significant number of them were not properly calibrated : 3) Initial audiometric testings were conducted at any available spaces in workplace or at the testing room without considering bachground noise level. One of solutions that can be done for sloving surrent noise related problems is to provide a noise related manual for the occupational health managers including doctors, nurses and hyginests. This study was done to provide such a manual. The main core of the manual was hearing conservation program. And the contents of the manual was the same as the main frame of hearing conservation program such as noise survey, provided of the diagram showing the core contents of each factor of the hearing conservation program. Hopefully, this manual will be the references of the standardized performances of the specific medical examination providers.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

공원묘지 유실에 의한 대량재해의 개인식별

강신몽,이한영,윤중진,이원태,김종열,이영석,서재관,최득린,서지석,이혜경 大韓法醫學會 1992 대한법의학회지 Vol.16 No.1

Individual identification of severely decomposed or skeletonized bodies is an important part in medicolegal field. 142 bodies were torn up and carried away by flood in a park cemetry, Kwang-Ju, Kyunggi province, Korea at Sept., 10, 1990. The authors examed the 56 bodies, which were gained, through medical, anthropological, odontological, radiological methods, and superimposition for individual identification. Among them, 41 cases were successfully identified, and remaining 15 cases were not identified because of sever destruction and no adequate information.

암환자의 건강문제 분류를 위한 횡단적 조사연구 : 서울시내 일개 종합병원 중심으로

김조자,이원희,유지수,허혜경,진혜영,최혜경 연세대학교 간호학연구소 1989 간호학 논집 Vol.12 No.1

The impact of cancer on human life has been recognized and the demand for care for the patient with cancer is ever increasing. Yet very little study around these concerns has been reported. The subjects of this study were 388 patients with cancer who were receiving treatment .in the outpatient department of Yonsei University Cancer Center. The study dealt with the health problems experienced while receiving this treatment. The research method used in this study was the structured interview technique using a questionnaire. Data collection was done between Dec. 1. l986 and June 30. 1987. The questionnaire used in this study was a revision of three questionnaires, one developed by D.W. McCaffrey(coping with cancer), one developed by C.A. Morris(self concept as altered by the diagnosis) and one developed by M.J. Yasko(management of symptoms associated with chemotherapy). Content validity was treated with oncologists and oneology nurses & nursing faculty members. The results and recommendation of the study areas follows: 1. Results. 1) Characteristics of the Sample The diagnoses of the subjects were as follow: The most frequent diagnosis was cancer of the stomach(26.5%), followed by breast cancer, lymphoma, rectal / colon cancer and lung cancer. The average age was 48.6 years. There were an equal number of men and women. There were 116(30.4%) subjects who received chemotherapy and surgery for the treatment of their disease of the total number of subjects. 264(69.5%) were treated for less than 1 year, and 116(30.5%) were treated for more than 1 year. The average Length of treatment was 12.7 months. 2) In Summary Health problems were categorized under four areas: physical. emotional, social and economical. The patients with lymphoma and stomach cancer experienced more health problems than any others in this study. According to the age of the patients, those in their 20's complained of physical and emotional problems most frequently and of those in their 30's social-economical concerns were most evident. In female gender. physical and emotional problems were identified more frequently than male patients. And yet male patients indicated greater concern with economic problems than female patients. Regardless of the treatment method or length of treatment health problems in different areas were similar and statistically not significant. However, economic concern was statistically significant(F = 2.52. p< 0.5) in those with receiving a combination of chemotherapy and radiation Marital status and health problems were also statistically significant. That is patients who were divorced, separated or widowed had more physical, psychological and economical problems than those who were married. 2. Recommendations. 1) Since the physical symptoms of nausea / muscle weakness and malnutrition were major health problems, the patient's diet and activity need to be carefully detailed and included in the care plan and further research is needed in order to implement physical, psychological. economical & spiritual interventions. 2) A follow up study should be done using a larger number of subjects and indifferent settings to further validate the health problem checklist for cancer patients.

Ektaspeed Plus 방사선사진, 간접 디지털 영상 및 Digora 영상의 치근단 병소의 판독능 비교

이희주,나경수,조봉혜 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.2

The comparative detectability of the artificial periapical defects among Ektaspeed Plus film, digitized and digora images was evaluated. The artifical defects were made in the cancellous bone and cancellous-cortical junction with the size of 1.0×0.8m㎡, 1.4×1.1m㎡ and 2.8×2.2m㎡. The defects in cancellous-cortical junction extended into cortical bone with the depth of 0, 0.5 and 1.0 mm. The results were as follows: 1. In junctional defects Ektaspeed Plus film for 2.8×12.2m㎡ defect showed the highest detectability. But siginificant difference were only found between Ektaspeed Plus films and digitized images(p<0.05). 2. Almost all defects within cacellous bone were not detected except a few digitized and Digora images for the size of 2.8×2.2m㎡. Digora images for them showed significant differences with Ektaspeed Plus films and digitized images(p<0.05). 3.The sensitinity of all imaging modalities were 0.9 or 1.0 in junctional defects for the size of 1.4×2.2m㎡ and 2.8×2.2m㎡. For cancellous defects, Digora image showed the highest sensitivity of 0.6 for the size of 2.8×2.2m㎡. 4. Siginificant differences for change of exposure time were found in most group of Ektaspeed Plus films and digitized images(p<0.05). But there was no significant differences in Digora images for cacellous defects.

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

導入種마늘의 主要形質과 生育特性에 關한 硏究 : Allium sativum L.

李敬姬,黃海鎭,吳仲烈,韓相政 대구효성가톨릭대학교 응용과학연구소 1995 응용과학연구논문집 Vol.4 No.-

導入育種의 一環으로 中國産 마늘 가운데서 球의 形質로 보아 優秀하다고 認定되는 上海種과 瀋陽種을 우리나라 代表品種인 義城種(寒地型) 및 濟州種(暖地型)과 함께 溫室과 圃場栽培 實驗으로 이들의 性能을 檢討한 결과를 要約하면 다음과 같다. 1) 上海, 瀋陽 및 濟州種은 無低溫區와 2∼3℃의 20日, 40日 및 60日間 低溫處理區에서 모두 播種後 約 1週日이 經過한 10月 20日 頃부터 萌芽하기 始作하였다. 萌芽期間은 上海種이 19∼22日, 그리고 濟州種이 17∼26日로서 低溫處理期間이 延長됨에 따라 短縮되었으나 瀋陽種은 低溫處理 與否에 關係없이 9∼12日 所要되었다. 2) 寒地型인 義城種은 無低溫區에서 播種後 74日이 經過한 12月 27日에 萌芽하기 始作하였으며, 低溫處理期間이 延長됨에 따라 漸次 빨라져서 60日間 處理區에서는 播種後 13日이 經過한 10月 26日에 萌芽가 始作되었다. 그리고 萌芽期間이 延長됨에 따라 顯著히 短縮되었다. 따라서 上海種과 瀋陽種은 暖地型이라고 認定되었다. 3) 圃場栽培에서 瀋陽種이 다른 品種에 比하여 根重, 球重 및 球當鱗片種이 가장 무거웠고, 球當鱗片數가 많았으며 또한 球高, 球徑 및 莖徑이 커서 品種間 差異가 있었으나 莖徑/球徑比는 供試 4品種 모두 0.2였다. 4) 上海種은 草長, 莖長 및 花梗長이 매우 짧으며 珠芽重은 0.3g로서 가장 가볍고 葉數가 많으며 葉幅이 컸다. 또한 暖地型인 上海, 瀋陽 및 濟州種의 추대기는 5月 12日로서 추대율은 100%였으나 寒地型인 義城種의 추대기는 6月 8日로서 추대율은 30%였다. 5) 供試 4品種의 植物全體의 乾物重은 播種後 135日 經過한 4月 7日부터, 그리고 球의 乾物重은 播種後 149日이 經過한 4月 21日부터 急激히 增加하였는데 이들中 瀋陽種이 가장 旺盛한 增加를 보였고 그 다음이 上海種이였다. 6) 供試 4品種의 줄기의 乾物重은 播種後 135日이 經過한 4월 7日부터 急激히 增加하였는데 이들중 上海種이 가장 旺盛하게 增加하였고 그 다음이 瀋陽種이였다. 그리고 잎의 乾物重은 緩慢하게 增加하였으나 瀋陽種이 가장 무거웠다. 葉面積은 瀋陽種이 가장 넓으며, 早期에 增加하기 始作하고 그 速度도 빨랐다. 7) 暖地型인 瀋陽種은 上海와 濟州種보다 早生으로서 生育이 旺盛하여 球重이 무겁고 燁數가 많으며 葉面積이 넓어서 우리나라 濟州道와 南海岸地帶에서 普通栽培와 冬季施設栽培에 利用할 수 있으리라고 믿어졌다. As a part of introduction breeding, two Chinese garlic cultivars, Shanghai and Shenyang, were cultivated in greenhouse and in field with two typical Korean cultivars, Euisung and Cheju, southern and northern ecotype respectively, and the characters and growth characteristics were investigated. 1. Shanghai, Shenyang and Cheju cultivars treated with low temperature of 2 ~ 3℃ for 20, 40 and 60 days and also the nontreated ones began to sprout from Oct. 20, about one week after planting. Sprouting periods were 19 ~ 22 and 17 ~ 26 days in Shanghai and Cheju cultivar, respectively. These periods were shortened as the low temperature treating periods were extended, but Shanghai cultivar needed 9 ~ 12 days for sprouting regardless of low temperature treatment. 2. A northern ecotype, Euisung cultivar, began to sprout on Dec. 27, 74 days after planting in period was extended, for 20 ~ 66 days, and began to sprout Oct.26, 13 days after planting. From this result, Shanghai and Shenyang cultivars were recognized as a southern ecotypes. 3. In field cultivation, root weight, bulb weight and clove weight per bulb were superior in Shenyang among all the four cultivars and had many cloves per bulb and also showed superior bulb height and blub diameter. These characters represented differences among cultivars, but the ratio of stem diameter to bulb diameter was 0.2 in all four cultivars. 4. Heights of plant, stem and flower stalk were the longest and the bulblet weight, 7.0g, were the heaviest in Shanghai cultivar. In Shenyang cultivar, the flower stalk was very short and the bulblet weight was light, 0.3g, but had many leaves and showed wide leaf width Shanghai, Shenyang and Cheju cultivars, southern ecotype ones, bolted on May 12 and the bolting ration was 100%, but Euisung cultivar, nothern ecotype, bolted on Jun. 8 and the bolting ra-tio was 30%. 5. Dry weight of whole plant and the bulb increased markedly from Apr. 7, 135 days after planting, and from Apr. 21, 149 days after planting, respectively, in all four cultivars, and Shenyang showed the most vigorous increment and Shanghai was next. 6. Stem dry weight increased markedly from Apr. 7, 135 days after planting in all four cultivars; and Shanghai showed the most vigorous increment and Shanghai was next. Leaf dry weight increased gradually and that of Shenyang were the heaviest one. Leaf area of Shenyang cultivar was most broad and grew early and rapidly. 7. Shenyang cultivar, a southern ecotype, grew earlier as compared with Shanghai and Cheju cultivars, and grew vigorously, and the bulb weight was heavy and had many broad leaves. It was considered that these two Chinese cultivars are possible to cultivate in Cheju and south coast districts of the Korean Peninsula by common method and in greenhouse during winter season.

한반도 통일에 대비한 안보의식 강화 방안

이경태,이해두 대구대학교 평화통일연구소 1993 平和統一硏究 Vol.10 No.-

前頭洞의 放射線學的 特徵에 依한 個人識別에 關한 硏究

李惠敬,文國鎭 고려대학교 의과대학 1987 고려대 의대 잡지 Vol.24 No.1

Individual identification procedure is one of the most important part in medicolegal field. Recently, radiological investigation methods have been widely applicated to the medicolegal field for the purpose of individual identification. So the author attempted to classify the types, size indices and indices of frontal sinuses by use of radiological patterns and measurements, and also investigated their distributions in Korean population according to sex and age by analysis of 967 cases of simple skull anteroposterior and lateral films. The results could be summarized as follows. 1. Anteroposterior frontal sinuses could be classified into 15 types according to their locations, numbers and relations, namely 0, L1, R1, R2, B1, B2U, B2N, B3U, B3N, B4U, B4N, B5U, B5N, B6U, and B9U types. 2. Lateral frontal sinuses could be classified into 9 types, according to their numbers and relations, namely, X, I, IIU, IIN, IIIU, IIIN, IVU, IVN, and VU types. 3. B2 types, which had 2 chambers in both sides, including B2U and B2N tyeps, occupied more than 1/2 (59.1%) of all cases. B2U type was more frequent in male, and B2N type, in female. Unilateral types occupied only 5.4%. 4. Lateral frontal sinus types showed no differences between male and female. IIU type was most frequent (38.3%). 5. O and X types, which did not identified in simple anteroposterior and lateral films revealed significant differences in frequency between those groups under 15 and over 15, so it should be interpreted that pneumatization of frontal sinuses proceed continuously upto 15. O and X types were more frequent in female than male over 15. 6. Size indices were greater in male than female in both anteroposterior and lateral films. They showed significant differences between under 15 and over 15 groups. 7. Frontal sinus indices were calculated by proportion of longitudinal and horizontal plane of quadriangle covering whole frontal sinuses. Anteroposterior indices showed no difference between both sexes, but lateral indices showed higher values in female than male. This study suggested the possibility of forensic indicator system of frontal sinuses by use of their types, size indices, and sinus indices revealed in simple anteroposterior and lateral views. The forenisc indicator system of frontal sinus would be useful in individual identification.