잉여슬러지 가용화를 위한 Lysozyme 생산 세균의 분리

구오펑페이 ( Peng Fei Guo ),김효상 ( Hyo Sang Kim ),오영기 ( Young Khee Oh ),이상도 ( Sang Do Lee ),장덕진 ( Deok Jin Jahng ) 한국물환경학회 2007 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2007 No.-

A Venture Capital Portfolio Model Based on Considering the allocation of both Capital Investment and management input

Peng Fei,Zhang Wei-guo,Tang Hai-rong 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10

The essence of Venture Capital is to nurture entrepreneurship and development by Capital support and consultive management services, which shows that venture capitalists" management support is of the same importance to the success of venture businesses as the capital support. The inputs of management and the investment of capital will together affect venture capitalists" specific choices of venture businesses. Assume that venture capitalists and venture entrepreneurs can reach an optimal contract, we put forward management input influence coefficient function, discussed its characters and constructed a general venture capital portfolio model and simplified model based on variance analysis by defining an management input impact factor and an expected profit function of a venture capital portfolio which is affected by the management input. A numerical example showed that optimize the allocation of funds and management input synthetically is very important for venture capital porfolio.

A Hierarchical Single-Surface Model for an Unsaturated Soil-Structure Interface

Fei Peng,Xin Li,Meng-fan Lv,Yong-Hui Li,Yuan-Cheng Guo 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.6

In this paper, according to the shear test of the interface between unsaturated soil and steel plate, the modified apparent roughness is used to describe interface roughness. And considering the influence of matrix suction and interface roughness, the stress variable is constructed to improve the yield and plastic potential functions. Then a modified hierarchical single-surface elastoplastic interface constitutive model (HISS-Unsaturated-Int model) is set up. The finite element calculation of HISS-Unsaturated-Int model is achieved by compiling and calling the user subroutine FRIC of ABAQUS. The interface shear test between unsaturated soil and structure with different water contents and the pull-out shear test between unsaturated soil and soil nail are simulated. The calculation results are consistent with those of experiments, which shows the modified interface constitutive model can effectively predict the shear mechanical properties of soil-structure interface under different soil moisture content, normal stress and interface roughness.

Association of XPD and XRCC1 Genetic Polymorphisms with Hepatocellular Carcinoma Risk

Guo, Lian-Yi,Jin, Xu-Peng,Niu, Wei,Li, Xiao-Fei,Liu, Bao-Hai,Wang, Yu-Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Aim: XRCC1 and XPD are two major repair genes involved in nucleotide excision repair (NER), which is reported to be associated with risk of several cancers. We explored the association of XRCC1 and XPD polymorphisms with the risk of HCC. Methods: A total of 410 cases with HCC and 410 health controls were collected. XRCC1 Arg194Trp, XRCC1 Arg399Gln, XPD Lys751Gln and XPD Asp312Asn genotyping was performed by duplex polymerase-chain-reaction with the confronting-two-pair primer (PCR-CTPP) method. Results: XRCC1 194Trp/Trp was strongly significantly associated with an increased risk of HCC cancer when compared with the wide-type genotype (OR=2.26, 95% CI=(1.23-5.38). Individuals carrying the XRCC1 399Gln/Gln showed increased risk of HCC (OR=1.74, 95%CI=1.06-2.74). The XPD 751Gln/Gln and Gln allele genotype were associated with strong elevated susceptibility to HCC (OR=3.51 and 1.42, respectively). Conclusion: These results suggest that polymorphisms in XRCC1 and XPD may have functional significance in risk of HCC.

Dynamic Allocation of Random Access Opportunity for Machine-Type Communication in LTE-Advanced

Peng Li,Yun-jian Jia,Ming-jun Feng,Fei Chen,Pei-hua He,Guo-jun Li 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.2

With the rapid growth of machine-type communications (MTC) devices, the radio access network (RAN) will be overloaded when a large number of MTC devices try to access the radio networks in a short time. In this paper, a combination of a dynamic resource allocation and a random access check mechanism is proposed to solve the overload problems for MTC in LTE-Advanced. An analytical model is presented with the derivation of three metrics, the collision probability, the success probability, and the idle probability to evaluate the method. Simulation and analysis results show the superior performance of the method we proposed to solve the RAN overload problem.

An Improved Conformal Mapping Method for Static Angular Eccentricity Analysis of Axial Flux Permanent Magnet Machines

Baocheng Guo,Yunkai Huang,Fei Peng 한국자기학회 2018 Journal of Magnetics Vol.23 No.1

This paper presents an improved and simple analytical model to study the static angular eccentricity of single stator single rotor axial-flux permanent-magnet (AFPM) machine. The magnetic flux densities in the air gap under normal and static angular eccentricity are calculated by using a combination of Maxwell’s equations and Schwarz-Christoffel (SC) transformation. The original contribution of the model is that angular eccentricity is obtained without extra transformations. Thus the proposed approach is simpler than existing methods. The calculated back electromotive forces (EMFs) and cogging torque by the proposed method are compared with those obtained from the finite element (FE) model, the results show acceptable accuracy of the proposed method. In this way, the effectiveness of the proposed method is verified.

Biotransformation, a Promising Technology for Anti-cancer Drug Development

Gao, Fei,Zhang, Jin-Ming,Wang, Zhan-Guo,Peng, Wei,Hu, Hui-Ling,Fu, Chao-Mei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

With the high morbidity and mortality caused by cancer, finding new and more effective anti-cancer drugs is very urgent. In current research, biotransformation plays a vital role in the research and development of cancer drugs and has obtained some achievements. In this review, we have summarized four applications as follows: to exploit novel anti-cancer drugs, to improve existing anti-cancer drugs, to broaden limited anti-cancer drug resources and to investigate correlative mechanisms. Three different groups of important anti-cancer compounds were assessed to clarify the current practical applications of biotransformation in the development of anti-cancer drugs.

Structural Damage Identification Based on Convolutional Neural Network Group Considering the Sensor Fault

Yong-Peng Luo,Linkun Wang,Xu Guo,Jinlin Zheng,Fei-Yu Liao,Zixiong Guo 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.8

This article proposes a structural damage identification method based on one-dimensional convolutional neural network group considering sensor faults. The method aims to reduce the damage misjudgment caused by sensor faults. In the proposed method, according to the sensor layout, some convolutional neural network sub-models are established to extract the features from raw vibration data for sensor fault diagnosis and structural damage identification; then two convolutional neural networks groups, namely the sensor fault diagnosis group and the damage identification group are designed on the basis of the functions of each sub-model. The sensor fault diagnosis group determines whether the sensor data is abnormal and truncates the abnormal signal. The remaining normal signal are entered into the damage identification group and the final damage identification results are calculated according to the statistical decision module. The effectiveness of the devised method is verified by the IASC–ASCE benchmark structure and laboratory experiments. The results demonstrate that the sensor fault diagnosis and damage identification accuracy of each sub-model ranges from 98.54% to 99.77% and from 87.21% to 91.74% respectively at different noise levels; the damage identification group can reduce the impact of sub-model misjudgment on the structural damage identification. The accuracy of the final damage identification results is 100%. The identification time of all samples in the test set is 53.09 s and 22.93 s, respectively, for SHM benchmark and Laboratory experiment cases. And the average judgment time of each submodel in the sensor fault diagnosis group was 278 and 94 ms, and that of each submodel in the damage identification group was 294 and 105 ms, respectively, for a single test sample, which fulfills the requirements of online damage identification for structural health monitoring.

Recoil reduction design of gas-controlled side-jet gun based on bifurcated twophase flow model

Ming Qiu,Fei Guo,Jie Song,Zhenqiang Liao,Peng Si 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.4

The high recoil force of a high-power gun produces a strong impact on the carrier, which severely limits the application of the high-power gun mounted on vehicles. A gascontrolled side-jet gun was designed to reduce the recoil force, and the gas-solid transient flow in the bifurcated tube of the gun was studied. First, a one-dimensional two-phase interior ballistics model was established considering the gas-solid coupling between the propellant gas and the valve in the front gas tube. Then, the propagation of the rarefaction wave in the barrel was studied, and the flow field distribution in the bifurcated tube was obtained. Finally, the mechanism of recoil reduction was analyzed. Results show that the bifurcated two-phase flow model can be used to accurately analyze the effect of the gas-controlled side-jet gun's parameters on the projectile velocity and the recoil reduction efficiency. The projectile velocities of the gascontrolled side-jet gun and the traditional gun are 955.7 m/s and 960 m/s, respectively. The projectile velocity loss of the gas-controlled side-jet gun is less than 0.5 %. The recoil momentum of the traditional gun and the gas-controlled side-jet gun are 538.62 N·s and 336.68 N·s, respectively. The recoil momentum of the gas-controlled side-jet gun decreases by 37.49 %. Additionally, the single firing time of the gas-controlled side-jet gun (18.91 ms) is less than that of the traditional single-barrel gun (more than 60 ms). Therefore, the newly designed gascontrolled side-jet gun significantly reduces the recoil momentum without losing the projectile velocity and continuous firing mode.

Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells

Xiaoxin Li,Lizhong Guo,Fei Huang,Wei Xu,Guiqing Peng 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.6

Cornuside is a secoiridoid glucoside compound extracted from the fruits of Cornus officinalis. Cornuside has immunomodulatory and anti-inflammatory properties; however, its potential therapeutic effects on diabetic nephropathy (DN) have not been completely explored. In this study, we established an in vitro model of DN through treating mesangial cells (MMCs) with glucose. MMCs were then treated with different concentrations of cornuside (0, 5, 10, and 30 μM). Cell viability was determined using cell counting kit-8 and 5-ethynyl-2′-deoxyuridine assays. Levels of proinflammatory cytokines, including interleukin (IL)-6, tumor necrosis factor-α, and IL- 1β were examined using enzyme-linked immunosorbent assay. Reverse transcription quantitative real-time polymerase chain reaction and Western blotting were performed to detect the expression of AKT and nuclear factor-kappa B (NF-κB)-associated genes. We found that cornuside treatment significantly reduced glucose-induced increase in MMC viability and expression of pro-inflammatory cytokines. Moreover, cornuside inhibited glucose-induced phosphorylation of AKT and NF-κB inhibitor alpha, decreased the expression of proliferating cell nuclear antigen and cyclin D1, and increased the expression of p21. Our study indicates that the anti-inflammatory properties of cornuside in DN are due to AKT and NF-κB inactivation in MMCs.